Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Metallothionein-1

Gene

MtnA

Organism
Drosophila simulans (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

This protein binds cations of several transition elements. It is thought to be involved in detoxification processes.

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCadmium, Copper, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein-1
Short name:
MT-1
Gene namesi
Name:MtnA
ORF Names:GD20757
OrganismiDrosophila simulans (Fruit fly)
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000304 Componentsi: Chromosome 3R, Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0012845 Dsim\MtnA

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001973541 – 40Metallothionein-1Add BLAST40

Expressioni

Developmental stagei

Late embryogenesis, larva and adult.

Inductioni

Strongly induced by cadmium, copper and mercury.

Gene expression databases

BgeeiFBgn0012845 Expressed in 4 organ(s), highest expression level in adult organism

Structurei

3D structure databases

SMRiP61874
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

All cysteine residues are arranged in C-X-C groups. These are thought to be the metal-binding sites in other metallothioneins.

Sequence similaritiesi

Phylogenomic databases

OrthoDBiEOG091G1A2R
PhylomeDBiP61874

Family and domain databases

InterProiView protein in InterPro
IPR000966 Metalthion_5
PfamiView protein in Pfam
PF02067 Metallothio_5, 1 hit
PRINTSiPR00872 MTDIPTERA

Sequencei

Sequence statusi: Complete.

P61874-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40
MPCPCGSGCK CASQATKGSC NCGSDCKCGG DKKSACGCSK
Length:40
Mass (Da):3,852
Last modified:June 7, 2004 - v1
Checksum:i9182A53CCCAE634A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55407 Unassigned DNA Translation: AAA03345.1
M69016 Unassigned DNA Translation: AAA19877.1
CM000364 Genomic DNA Translation: EDX13558.1
PIRiB61194
RefSeqiXP_002104055.1, XM_002104019.2

Genome annotation databases

EnsemblMetazoaiFBtr0220667; FBpp0219159; FBgn0012845
GeneIDi6728719
KEGGidsi:Dsimw501_GD20757

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55407 Unassigned DNA Translation: AAA03345.1
M69016 Unassigned DNA Translation: AAA19877.1
CM000364 Genomic DNA Translation: EDX13558.1
PIRiB61194
RefSeqiXP_002104055.1, XM_002104019.2

3D structure databases

SMRiP61874
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0220667; FBpp0219159; FBgn0012845
GeneIDi6728719
KEGGidsi:Dsimw501_GD20757

Organism-specific databases

FlyBaseiFBgn0012845 Dsim\MtnA

Phylogenomic databases

OrthoDBiEOG091G1A2R
PhylomeDBiP61874

Miscellaneous databases

ChiTaRSiMtnA fly

Gene expression databases

BgeeiFBgn0012845 Expressed in 4 organ(s), highest expression level in adult organism

Family and domain databases

InterProiView protein in InterPro
IPR000966 Metalthion_5
PfamiView protein in Pfam
PF02067 Metallothio_5, 1 hit
PRINTSiPR00872 MTDIPTERA
ProtoNetiSearch...

Entry informationi

Entry nameiMT1_DROSI
AccessioniPrimary (citable) accession number: P61874
Secondary accession number(s): B4QVX8, P22254
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: June 7, 2004
Last modified: September 12, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Metallothioneins
    Classification of metallothioneins and list of entries
  3. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again