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UniProtKB - P61601 (NCALD_HUMAN)

Entry version 155 (23 Feb 2022)
Sequence version 2 (23 Jan 2007)
Previous versions | rss
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Protein

Neurocalcin-delta

Gene

NCALD

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi73Calcium 1PROSITE-ProRule annotation1
Metal bindingi75Calcium 1PROSITE-ProRule annotation1
Metal bindingi77Calcium 1PROSITE-ProRule annotation1
Metal bindingi79Calcium 1PROSITE-ProRule annotation1
Metal bindingi84Calcium 1PROSITE-ProRule annotation1
Metal bindingi109Calcium 2PROSITE-ProRule annotation1
Metal bindingi111Calcium 2PROSITE-ProRule annotation1
Metal bindingi113Calcium 2PROSITE-ProRule annotation1
Metal bindingi115Calcium 2PROSITE-ProRule annotation1
Metal bindingi120Calcium 2PROSITE-ProRule annotation1
Metal bindingi157Calcium 3PROSITE-ProRule annotation1
Metal bindingi159Calcium 3PROSITE-ProRule annotation1
Metal bindingi161Calcium 3PROSITE-ProRule annotation1
Metal bindingi163Calcium 3PROSITE-ProRule annotation1
Metal bindingi168Calcium 3PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalcium, Metal-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P61601

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-451308, Activation of Ca-permeable Kainate Receptor

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		P61601

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Neurocalcin-delta
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NCALD
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:7655, NCALD

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		606722, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P61601

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000104490

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		83988

Open Targets

More...OpenTargetsi		ENSG00000104490

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA31458

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P61601, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		NCALD

Domain mapping of disease mutations (DMDM)

More...DMDMi		47606440

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000737822 – 193Neurocalcin-deltaAdd BLAST192

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi2N-myristoyl glycineBy similarity1

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P61601

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P61601

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P61601

MaxQB - The MaxQuant DataBase

More...MaxQBi		P61601

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P61601

PeptideAtlas

More...PeptideAtlasi		P61601

PRoteomics IDEntifications database

More...PRIDEi		P61601

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		57324

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P61601

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P61601

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000104490, Expressed in Brodmann (1909) area 10 and 202 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P61601, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P61601, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000104490, Tissue enhanced (salivary)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with GUCY2D.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		123839, 49 interactors

Protein interaction database and analysis system

More...IntActi		P61601, 36 interactors

Molecular INTeraction database

More...MINTi		P61601

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000379256

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P61601, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P61601

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini40 – 58EF-hand 1PROSITE-ProRule annotationAdd BLAST19
Domaini60 – 95EF-hand 2PROSITE-ProRule annotationAdd BLAST36
Domaini96 – 131EF-hand 3PROSITE-ProRule annotationAdd BLAST36
Domaini144 – 179EF-hand 4PROSITE-ProRule annotationAdd BLAST36

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the recoverin family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0044, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000158862

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_072366_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P61601

Identification of Orthologs from Complete Genome Data

More...OMAi		LWSKGWN

Database for complete collections of gene phylogenies

More...PhylomeDBi		P61601

TreeFam database of animal gene trees

More...TreeFami		TF300009

Family and domain databases

Conserved Domains Database

More...CDDi		cd00051, EFh, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR028846, Recoverin

The PANTHER Classification System

More...PANTHERi		PTHR23055, PTHR23055, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13499, EF-hand_7, 1 hit
PF13833, EF-hand_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00054, EFh, 3 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47473, SSF47473, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00018, EF_HAND_1, 3 hits
PS50222, EF_HAND_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All

P61601-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKQNSKLRP EVMQDLLEST DFTEHEIQEW YKGFLRDCPS GHLSMEEFKK 
        60         70         80         90        100
IYGNFFPYGD ASKFAEHVFR TFDANGDGTI DFREFIIALS VTSRGKLEQK 
       110        120        130        140        150
LKWAFSMYDL DGNGYISKAE MLEIVQAIYK MVSSVMKMPE DESTPEKRTE 
       160        170        180        190 
KIFRQMDTNR DGKLSLEEFI RGAKSDPSIV RLLQCDPSSA GQF
Length:193
Mass (Da):22,245
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i20DD8B6FF47C4CBF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E5RI78E5RI78_HUMAN
Neurocalcin-delta
NCALD
116Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RHE8E5RHE8_HUMAN
Neurocalcin-delta
NCALD
112Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RGA9E5RGA9_HUMAN
Neurocalcin-delta
NCALD
194Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RIZ1E5RIZ1_HUMAN
Neurocalcin-delta
NCALD
136Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RHC8E5RHC8_HUMAN
Neurocalcin-delta
NCALD
120Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RIA5E5RIA5_HUMAN
Neurocalcin-delta
NCALD
152Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RIG4E5RIG4_HUMAN
Neurocalcin-delta
NCALD
121Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RJJ6E5RJJ6_HUMAN
Neurocalcin-delta
NCALD
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RGZ0E5RGZ0_HUMAN
Neurocalcin-delta
NCALD
87Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RJT1E5RJT1_HUMAN
Neurocalcin-delta
NCALD
81Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti123E → V in CAB66547 (PubMed:11230166).Curated1
Sequence conflicti166L → M in AAH36098 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF251061 mRNA Translation: AAK34951.1
AL136612 mRNA Translation: CAB66547.1
BC036098 mRNA Translation: AAH36098.1
BC063428 mRNA Translation: AAH63428.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS6292.1

NCBI Reference Sequences

More...RefSeqi		NP_001035714.1, NM_001040624.1
NP_001035715.1, NM_001040625.1
NP_001035716.1, NM_001040626.1
NP_001035717.1, NM_001040627.1
NP_001035718.1, NM_001040628.1
NP_001035719.1, NM_001040629.1
NP_001035720.1, NM_001040630.1
NP_114430.2, NM_032041.2
XP_011515634.1, XM_011517332.2
XP_011515635.1, XM_011517333.2
XP_011515636.1, XM_011517334.2
XP_011515637.1, XM_011517335.2
XP_016869390.1, XM_017013901.1
XP_016869391.1, XM_017013902.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000220931; ENSP00000220931; ENSG00000104490
ENST00000311028; ENSP00000310587; ENSG00000104490
ENST00000395923; ENSP00000379256; ENSG00000104490
ENST00000519508; ENSP00000430476; ENSG00000104490
ENST00000521599; ENSP00000428105; ENSG00000104490

Database of genes from NCBI RefSeq genomes

More...GeneIDi		83988

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:83988

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000220931.11; ENSP00000220931.6; NM_032041.3; NP_114430.2

UCSC genome browser

More...UCSCi		uc003yke.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF251061 mRNA Translation: AAK34951.1
AL136612 mRNA Translation: CAB66547.1
BC036098 mRNA Translation: AAH36098.1
BC063428 mRNA Translation: AAH63428.1
CCDSiCCDS6292.1
RefSeqiNP_001035714.1, NM_001040624.1
NP_001035715.1, NM_001040625.1
NP_001035716.1, NM_001040626.1
NP_001035717.1, NM_001040627.1
NP_001035718.1, NM_001040628.1
NP_001035719.1, NM_001040629.1
NP_001035720.1, NM_001040630.1
NP_114430.2, NM_032041.2
XP_011515634.1, XM_011517332.2
XP_011515635.1, XM_011517333.2
XP_011515636.1, XM_011517334.2
XP_011515637.1, XM_011517335.2
XP_016869390.1, XM_017013901.1
XP_016869391.1, XM_017013902.1

3D structure databases

SMRiP61601
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi123839, 49 interactors
IntActiP61601, 36 interactors
MINTiP61601
STRINGi9606.ENSP00000379256

PTM databases

iPTMnetiP61601
PhosphoSitePlusiP61601

Genetic variation databases

BioMutaiNCALD
DMDMi47606440

Proteomic databases

EPDiP61601
jPOSTiP61601
MassIVEiP61601
MaxQBiP61601
PaxDbiP61601
PeptideAtlasiP61601
PRIDEiP61601
ProteomicsDBi57324

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		42836, 172 antibodies from 27 providers

The DNASU plasmid repository

More...DNASUi		83988

Genome annotation databases

EnsembliENST00000220931; ENSP00000220931; ENSG00000104490
ENST00000311028; ENSP00000310587; ENSG00000104490
ENST00000395923; ENSP00000379256; ENSG00000104490
ENST00000519508; ENSP00000430476; ENSG00000104490
ENST00000521599; ENSP00000428105; ENSG00000104490
GeneIDi83988
KEGGihsa:83988
MANE-SelectiENST00000220931.11; ENSP00000220931.6; NM_032041.3; NP_114430.2
UCSCiuc003yke.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		83988
DisGeNETi83988

GeneCards: human genes, protein and diseases

More...GeneCardsi		NCALD
HGNCiHGNC:7655, NCALD
HPAiENSG00000104490, Tissue enhanced (salivary)
MIMi606722, gene
neXtProtiNX_P61601
OpenTargetsiENSG00000104490
PharmGKBiPA31458
VEuPathDBiHostDB:ENSG00000104490

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0044, Eukaryota
GeneTreeiENSGT00940000158862
HOGENOMiCLU_072366_1_0_1
InParanoidiP61601
OMAiLWSKGWN
PhylomeDBiP61601
TreeFamiTF300009

Enzyme and pathway databases

PathwayCommonsiP61601
ReactomeiR-HSA-451308, Activation of Ca-permeable Kainate Receptor
SignaLinkiP61601

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		83988, 8 hits in 1045 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		NCALD, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		83988
PharosiP61601, Tbio

Protein Ontology

More...PROi		PR:P61601
RNActiP61601, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000104490, Expressed in Brodmann (1909) area 10 and 202 other tissues
ExpressionAtlasiP61601, baseline and differential
GenevisibleiP61601, HS

Family and domain databases

CDDicd00051, EFh, 2 hits
InterProiView protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR028846, Recoverin
PANTHERiPTHR23055, PTHR23055, 1 hit
PfamiView protein in Pfam
PF13499, EF-hand_7, 1 hit
PF13833, EF-hand_8, 1 hit
SMARTiView protein in SMART
SM00054, EFh, 3 hits
SUPFAMiSSF47473, SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018, EF_HAND_1, 3 hits
PS50222, EF_HAND_2, 4 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNCALD_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P61601
Secondary accession number(s): P29554, Q8IYC3, Q9H0W2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: January 23, 2007
Last modified: February 23, 2022
This is version 155 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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