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Protein

Superoxide dismutase [Mn]

Gene

sodA

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.By similarity

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Mn2+By similarityNote: Binds 1 Mn2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi29ManganeseBy similarity1
Metal bindingi84ManganeseBy similarity1
Metal bindingi167ManganeseBy similarity1
Metal bindingi171ManganeseBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn] (EC:1.15.1.1)
Gene namesi
Name:sodA
Ordered Locus Names:TT_C0189
OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Taxonomic identifieri262724 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000592 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001601072 – 204Superoxide dismutase [Mn]Add BLAST203

Interactioni

Subunit structurei

Homotetramer.By similarity

Protein-protein interaction databases

STRINGi262724.TTC0189

Structurei

3D structure databases

ProteinModelPortaliP61502
SMRiP61502
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CK4 Bacteria
COG0605 LUCA
KOiK04564
OMAiKWGSFDK

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P61502-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPYPFKLPDL GYPYEALEPH IDAKTMEIHH QKHHGAYVTN LNAALEKYPY
60 70 80 90 100
LHGVEVEVLL RHLAALPQDI QTAVRNNGGG HLNHSLFWRL LTPGGAKEPV
110 120 130 140 150
GELKKAIDEQ FGGFQALKEK LTQAAMGRFG SGWAWLVKDP FGKLHVLSTP
160 170 180 190 200
NQDNPVMEGF TPIVGIDVWE HAYYLKYQNR RADYLQAIWN VLNWDVAEEF

FKKA
Length:204
Mass (Da):23,230
Last modified:January 23, 2007 - v2
Checksum:i37B9C1956FD8D46B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB010884 Genomic DNA Translation: BAA25701.1
AE017221 Genomic DNA Translation: AAS80537.1
PIRiT43728
RefSeqiWP_011172643.1, NC_005835.1

Genome annotation databases

EnsemblBacteriaiAAS80537; AAS80537; TT_C0189
KEGGitth:TT_C0189

Similar proteinsi

Entry informationi

Entry nameiSODM_THET2
AccessioniPrimary (citable) accession number: P61502
Secondary accession number(s): P09214
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 74 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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