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Protein

10 kDa chaperonin

Gene

groS

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone

Enzyme and pathway databases

BioCyciTTHE300852:G1GKC-285-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
10 kDa chaperonin
Alternative name(s):
GroES protein
Protein Cpn10
Gene namesi
Name:groS
Synonyms:chpS, groES, hsp10
Ordered Locus Names:TTHA0272
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001748862 – 10110 kDa chaperoninAdd BLAST100

Interactioni

Subunit structurei

Heptamer of 7 subunits arranged in a ring.By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
groLQ5SLM22EBI-15757522,EBI-15757498

Protein-protein interaction databases

DIPiDIP-48332N
IntActiP61493, 1 interactor
STRINGi300852.TTHA0272

Structurei

Secondary structure

1101
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP61493
SMRiP61493
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP61493

Family & Domainsi

Sequence similaritiesi

Belongs to the GroES chaperonin family.Curated

Phylogenomic databases

eggNOGiENOG4105K5Y Bacteria
COG0234 LUCA
HOGENOMiHOG000133897
KOiK04078
OMAiPGRIDDN
PhylomeDBiP61493

Family and domain databases

CDDicd00320 cpn10, 1 hit
Gene3Di2.30.33.40, 1 hit
HAMAPiMF_00580 CH10, 1 hit
InterProiView protein in InterPro
IPR020818 Chaperonin_GroES
IPR037124 Chaperonin_GroES_sf
IPR018369 Chaprnonin_Cpn10_CS
IPR011032 GroES-like_sf
PANTHERiPTHR10772 PTHR10772, 1 hit
PfamiView protein in Pfam
PF00166 Cpn10, 1 hit
PRINTSiPR00297 CHAPERONIN10
SMARTiView protein in SMART
SM00883 Cpn10, 1 hit
SUPFAMiSSF50129 SSF50129, 1 hit
PROSITEiView protein in PROSITE
PS00681 CHAPERONINS_CPN10, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P61493-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAEVKTVIK PLGDRVVVKR IEEEPKTKGG IVLPDTAKEK PQKGKVIAVG
60 70 80 90 100
TGRVLENGQR VPLEVKEGDI VVFAKYGGTE IEIDGEEYVI LSERDLLAVL

Q
Length:101
Mass (Da):10,996
Last modified:January 23, 2007 - v2
Checksum:i49DCA870AC325063
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti20R → K AA sequence (PubMed:1682319).Curated1
Sequence conflicti84 – 87DGEE → APRRT in AAA83440 (Ref. 2) Curated4

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D45880 Genomic DNA Translation: BAA08298.1
U29483 Genomic DNA Translation: AAA83440.1
AP008226 Genomic DNA Translation: BAD70095.1
PIRiB39313
RefSeqiWP_011174076.1, NC_006461.1
YP_143538.1, NC_006461.1

Genome annotation databases

EnsemblBacteriaiBAD70095; BAD70095; BAD70095
GeneIDi3168828
KEGGittj:TTHA0272
PATRICifig|300852.9.peg.272

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D45880 Genomic DNA Translation: BAA08298.1
U29483 Genomic DNA Translation: AAA83440.1
AP008226 Genomic DNA Translation: BAD70095.1
PIRiB39313
RefSeqiWP_011174076.1, NC_006461.1
YP_143538.1, NC_006461.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1WNRX-ray2.90A/B/C/D/E/F/G9-101[»]
ProteinModelPortaliP61493
SMRiP61493
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48332N
IntActiP61493, 1 interactor
STRINGi300852.TTHA0272

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD70095; BAD70095; BAD70095
GeneIDi3168828
KEGGittj:TTHA0272
PATRICifig|300852.9.peg.272

Phylogenomic databases

eggNOGiENOG4105K5Y Bacteria
COG0234 LUCA
HOGENOMiHOG000133897
KOiK04078
OMAiPGRIDDN
PhylomeDBiP61493

Enzyme and pathway databases

BioCyciTTHE300852:G1GKC-285-MONOMER

Miscellaneous databases

EvolutionaryTraceiP61493

Family and domain databases

CDDicd00320 cpn10, 1 hit
Gene3Di2.30.33.40, 1 hit
HAMAPiMF_00580 CH10, 1 hit
InterProiView protein in InterPro
IPR020818 Chaperonin_GroES
IPR037124 Chaperonin_GroES_sf
IPR018369 Chaprnonin_Cpn10_CS
IPR011032 GroES-like_sf
PANTHERiPTHR10772 PTHR10772, 1 hit
PfamiView protein in Pfam
PF00166 Cpn10, 1 hit
PRINTSiPR00297 CHAPERONIN10
SMARTiView protein in SMART
SM00883 Cpn10, 1 hit
SUPFAMiSSF50129 SSF50129, 1 hit
PROSITEiView protein in PROSITE
PS00681 CHAPERONINS_CPN10, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCH10_THET8
AccessioniPrimary (citable) accession number: P61493
Secondary accession number(s): P45747, Q5SLM1, Q60017
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: January 23, 2007
Last modified: October 10, 2018
This is version 93 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
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