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Protein

60S ribosomal protein L27

Gene

RPL27

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Component of the large ribosomal subunit.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-GGA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-GGA-72689 Formation of a pool of free 40S subunits
R-GGA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-GGA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-GGA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L27
Gene namesi
Name:RPL27
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 27

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001260802 – 13660S ribosomal protein L27Add BLAST135

Proteomic databases

PaxDbiP61355

Expressioni

Gene expression databases

BgeeiENSGALG00000002837 Expressed in 11 organ(s), highest expression level in female gonad

Interactioni

Subunit structurei

Component of the large ribosomal subunit.By similarity

Protein-protein interaction databases

BioGridi676539, 1 interactor
STRINGi9031.ENSGALP00000038957

Structurei

3D structure databases

ProteinModelPortaliP61355
SMRiP61355
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 40KOWAdd BLAST36

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3418 Eukaryota
COG2163 LUCA
GeneTreeiENSGT00390000010721
HOGENOMiHOG000210138
HOVERGENiHBG050005
InParanoidiP61355
KOiK02901
OMAiRYPRKVH
OrthoDBiEOG091G0YBM
PhylomeDBiP61355
TreeFamiTF314648

Family and domain databases

Gene3Di2.30.30.770, 1 hit
InterProiView protein in InterPro
IPR005824 KOW
IPR038655 L27e_sf
IPR001141 Ribosomal_L27e
IPR018262 Ribosomal_L27e_CS
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR10497 PTHR10497, 1 hit
PfamiView protein in Pfam
PF00467 KOW, 1 hit
PF01777 Ribosomal_L27e, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD009396 Ribosomal_L27e, 1 hit
SMARTiView protein in SMART
SM00739 KOW, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
PROSITEiView protein in PROSITE
PS01107 RIBOSOMAL_L27E, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.iShow all

P61355-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP
60 70 80 90 100
RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDIP LDKTVVNKDV
110 120 130
FRDPALKRKA RREAKVKFEE RYKTGKNKWF FQKLRF
Length:136
Mass (Da):15,798
Last modified:January 23, 2007 - v2
Checksum:i73F4151495029A32
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1L1RW37A0A1L1RW37_CHICK
60S ribosomal protein L27
RPL27
80Annotation score:
A0A1L1RRD6A0A1L1RRD6_CHICK
60S ribosomal protein L27
RPL27
53Annotation score:
A0A1L1RKT9A0A1L1RKT9_CHICK
60S ribosomal protein L27
RPL27
56Annotation score:
A0A1L1RLQ0A0A1L1RLQ0_CHICK
60S ribosomal protein L27
RPL27
121Annotation score:
A0A1L1RTZ2A0A1L1RTZ2_CHICK
60S ribosomal protein L27
RPL27
105Annotation score:
A0A1L1RRZ8A0A1L1RRZ8_CHICK
60S ribosomal protein L27
RPL27
87Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56852 mRNA Translation: CAA40181.1
PIRiS22288
RefSeqiNP_990668.1, NM_205337.1
UniGeneiGga.743

Genome annotation databases

EnsembliENSGALT00000039748; ENSGALP00000038957; ENSGALG00000002837
ENSGALT00000048570; ENSGALP00000044547; ENSGALG00000002837
GeneIDi396280
KEGGigga:396280

Similar proteinsi

Entry informationi

Entry nameiRL27_CHICK
AccessioniPrimary (citable) accession number: P61355
Secondary accession number(s): P08526
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: January 23, 2007
Last modified: September 12, 2018
This is version 93 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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