Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60S ribosomal protein L27

Gene

Rpl27

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Component of the large ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

  • response to aldosterone Source: RGD
  • rRNA processing Source: UniProtKB
  • translation Source: InterPro

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L27
Gene namesi
Name:Rpl27
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi621192 Rpl27

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001260791 – 13660S ribosomal protein L27Add BLAST136

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei27N6-acetyllysineBy similarity1
Modified residuei93N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiP61354
PRIDEiP61354

PTM databases

iPTMnetiP61354
PhosphoSitePlusiP61354
SwissPalmiP61354

Expressioni

Gene expression databases

BgeeiENSRNOG00000020674
GenevisibleiP61354 RN

Interactioni

Subunit structurei

Component of the large ribosomal subunit (By similarity). Interacts with RRP1B (By similarity). Component of the large ribosomal subunit. Interacts with RRP1B. Interacts with DHX33 (By similarity).By similarity

Protein-protein interaction databases

BioGridi249021, 3 interactors
IntActiP61354, 2 interactors
STRINGi10116.ENSRNOP00000028060

Structurei

3D structure databases

ProteinModelPortaliP61354
SMRiP61354
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 40KOWAdd BLAST36

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3418 Eukaryota
COG2163 LUCA
GeneTreeiENSGT00390000010721
HOGENOMiHOG000210138
HOVERGENiHBG050005
InParanoidiP61354
KOiK02901
OMAiRYPRKVH
OrthoDBiEOG091G0YBM
PhylomeDBiP61354
TreeFamiTF314648

Family and domain databases

Gene3Di2.30.30.770, 1 hit
InterProiView protein in InterPro
IPR005824 KOW
IPR038655 L27e_sf
IPR001141 Ribosomal_L27e
IPR018262 Ribosomal_L27e_CS
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR10497 PTHR10497, 1 hit
PfamiView protein in Pfam
PF00467 KOW, 1 hit
PF01777 Ribosomal_L27e, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD009396 Ribosomal_L27e, 1 hit
SMARTiView protein in SMART
SM00739 KOW, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
PROSITEiView protein in PROSITE
PS01107 RIBOSOMAL_L27E, 1 hit

Sequencei

Sequence statusi: Complete.

P61354-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP
60 70 80 90 100
RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDIP LDKTVVNKDV
110 120 130
FRDPALKRKA RREAKVKFEE RYKTGKNKWF FQKLRF
Length:136
Mass (Da):15,798
Last modified:January 23, 2007 - v2
Checksum:i73F4151495029A32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07424 mRNA Translation: CAA30313.1
BC058474 mRNA Translation: AAH58474.1
BC091566 mRNA Translation: AAH91566.1
PIRiS00401 R5RT27
RefSeqiNP_071959.1, NM_022514.1
UniGeneiRn.1254

Genome annotation databases

EnsembliENSRNOT00000028060; ENSRNOP00000028060; ENSRNOG00000020674
GeneIDi64306
KEGGirno:64306
UCSCiRGD:621192 rat

Similar proteinsi

Entry informationi

Entry nameiRL27_RAT
AccessioniPrimary (citable) accession number: P61354
Secondary accession number(s): P08526, Q5BJ97
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 106 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health