Rpl27

Functionⁱ

Component of the large ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (By similarity).By similarity

GO - Molecular functionⁱ

structural constituent of ribosome Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

response to aldosterone
Source: RGD
Inferred from expression patternⁱ
- 24303148
rRNA processing Source: UniProtKB
translation Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Ribonucleoprotein, Ribosomal protein

Molecular function

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 60S ribosomal protein L27
Gene namesⁱ	Name:Rpl27
Organismⁱ	Rattus norvegicus (Rat)
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 10

Organism-specific databases

Rat genome database More...RGDⁱ	621192 Rpl27

RGDⁱ

621192 Rpl27

Keywords - Cellular componentⁱ

Cytoplasm, Endoplasmic reticulum

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000126079	1 – 136	60S ribosomal protein L27Add BLAST		136

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	27	N6-acetyllysineBy similarity		1
Modified residueⁱ	93	N6-acetyllysineBy similarity		1

Keywords - PTMⁱ

Acetylation

Proteomic databases

PaxDbⁱ	P61354
PRIDEⁱ	P61354

PTM databases

iPTMnetⁱ	P61354
PhosphoSitePlusⁱ	P61354
SwissPalmⁱ	P61354

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000020674
Genevisibleⁱ	P61354 RN

Interactionⁱ

Subunit structureⁱ

Component of the large ribosomal subunit (By similarity). Interacts with RRP1B (By similarity). Component of the large ribosomal subunit. Interacts with RRP1B. Interacts with DHX33 (By similarity).By similarity

Protein-protein interaction databases

BioGridⁱ	249021, 3 interactors
IntActⁱ	P61354, 2 interactors
STRINGⁱ	10116.ENSRNOP00000028060

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P61354
SMRⁱ	P61354
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	5 – 40	KOWAdd BLAST		36

Sequence similaritiesⁱ

Belongs to the eukaryotic ribosomal protein eL27 family.Curated

Phylogenomic databases

eggNOGⁱ	KOG3418 Eukaryota COG2163 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000010721
HOGENOMⁱ	HOG000210138
HOVERGENⁱ	HBG050005
InParanoidⁱ	P61354
KEGG Orthology (KO) More...KOⁱ	K02901
OMAⁱ	RYPRKVH
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0YBM
PhylomeDBⁱ	P61354
TreeFamⁱ	TF314648

Family and domain databases

Gene3Dⁱ	2.30.30.770, 1 hit
InterProⁱ	View protein in InterPro IPR005824 KOW IPR038655 L27e_sf IPR001141 Ribosomal_L27e IPR018262 Ribosomal_L27e_CS IPR008991 Translation_prot_SH3-like_sf
PANTHERⁱ	PTHR10497 PTHR10497, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00467 KOW, 1 hit PF01777 Ribosomal_L27e, 1 hit
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD009396 Ribosomal_L27e, 1 hit
SMARTⁱ	View protein in SMART SM00739 KOW, 1 hit
SUPFAMⁱ	SSF50104 SSF50104, 1 hit
PROSITEⁱ	View protein in PROSITE PS01107 RIBOSOMAL_L27E, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P61354-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP 
        60         70         80         90        100
RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDIP LDKTVVNKDV 
       110        120        130 
FRDPALKRKA RREAKVKFEE RYKTGKNKWF FQKLRF

Length:136

Mass (Da):15,798

Last modified:January 23, 2007 - v2

Checksum:ⁱ73F4151495029A32

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X07424 mRNA Translation: CAA30313.1 BC058474 mRNA Translation: AAH58474.1 BC091566 mRNA Translation: AAH91566.1
PIRⁱ	S00401 R5RT27
NCBI Reference Sequences More...RefSeqⁱ	NP_071959.1, NM_022514.1
UniGeneⁱ	Rn.1254

Genome annotation databases

Ensemblⁱ	ENSRNOT00000028060; ENSRNOP00000028060; ENSRNOG00000020674
GeneIDⁱ	64306
KEGGⁱ	rno:64306
UCSC genome browser More...UCSCⁱ	RGD:621192 rat

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
P61354	60S ribosomal protein L27	)	HUMAN		136
60S ribosomal protein L27		BOVIN		136
60S ribosomal protein L27		CERNI		136
60S ribosomal protein L27		CHICK		136
60S ribosomal protein L27		MACFA		136
+55

Protein	Similar proteins		Species	Score	Length
P61354	60S ribosomal protein L27	)	HUMAN		136
60S ribosomal protein L27		BOVIN		136
60S ribosomal protein L27		CERNI		136
60S ribosomal protein L27		CHICK		136
60S ribosomal protein L27		MACFA		136
+57

Protein	Similar proteins		Species	Score	Length
P61354	60S ribosomal protein L27	)	HUMAN		136
60S ribosomal protein L27		BOVIN		136
60S ribosomal protein L27		CERNI		136
60S ribosomal protein L27		CHICK		136
60S ribosomal protein L27		MACFA		136
+83

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X07424 mRNA Translation: CAA30313.1 BC058474 mRNA Translation: AAH58474.1 BC091566 mRNA Translation: AAH91566.1
PIRⁱ	S00401 R5RT27
NCBI Reference Sequences More...RefSeqⁱ	NP_071959.1, NM_022514.1
UniGeneⁱ	Rn.1254

3D structure databases

ProteinModelPortalⁱ	P61354
SMRⁱ	P61354
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	249021, 3 interactors
IntActⁱ	P61354, 2 interactors
STRINGⁱ	10116.ENSRNOP00000028060

PTM databases

iPTMnetⁱ	P61354
PhosphoSitePlusⁱ	P61354
SwissPalmⁱ	P61354

Proteomic databases

PaxDbⁱ	P61354
PRIDEⁱ	P61354

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000028060; ENSRNOP00000028060; ENSRNOG00000020674
GeneIDⁱ	64306
KEGGⁱ	rno:64306
UCSC genome browser More...UCSCⁱ	RGD:621192 rat

Organism-specific databases

CTDⁱ	6155
Rat genome database More...RGDⁱ	621192 Rpl27

Phylogenomic databases

eggNOGⁱ	KOG3418 Eukaryota COG2163 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000010721
HOGENOMⁱ	HOG000210138
HOVERGENⁱ	HBG050005
InParanoidⁱ	P61354
KEGG Orthology (KO) More...KOⁱ	K02901
OMAⁱ	RYPRKVH
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0YBM
PhylomeDBⁱ	P61354
TreeFamⁱ	TF314648

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P61354

PROⁱ

PR:P61354

Gene expression databases

Bgeeⁱ	ENSRNOG00000020674
Genevisibleⁱ	P61354 RN

Family and domain databases

Gene3Dⁱ	2.30.30.770, 1 hit
InterProⁱ	View protein in InterPro IPR005824 KOW IPR038655 L27e_sf IPR001141 Ribosomal_L27e IPR018262 Ribosomal_L27e_CS IPR008991 Translation_prot_SH3-like_sf
PANTHERⁱ	PTHR10497 PTHR10497, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00467 KOW, 1 hit PF01777 Ribosomal_L27e, 1 hit
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD009396 Ribosomal_L27e, 1 hit
SMARTⁱ	View protein in SMART SM00739 KOW, 1 hit
SUPFAMⁱ	SSF50104 SSF50104, 1 hit
PROSITEⁱ	View protein in PROSITE PS01107 RIBOSOMAL_L27E, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RL27_RAT
Accessionⁱ	P61354Primary (citable) accession number: P61354 Secondary accession number(s): P08526, Q5BJ97
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	August 1, 1988
	Last sequence update:	January 23, 2007
	Last modified:	May 23, 2018
	This is version 106 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

UniProtKB

UniParc

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Supporting data

UniProtKB - P61354 (RL27_RAT)

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60S ribosomal protein L27

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Endoplasmic reticulum

Cytosol

Other locations

Cytosol

Endoplasmic reticulum

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ