UniProtKB - P61289 (PSME3_HUMAN)
Proteasome activator complex subunit 3
PSME3
Functioni
GO - Molecular functioni
- endopeptidase activator activity Source: UniProtKB
- identical protein binding Source: IntAct
- MDM2/MDM4 family protein binding Source: UniProtKB
- p53 binding Source: UniProtKB
GO - Biological processi
- anaphase-promoting complex-dependent catabolic process Source: Reactome
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent Source: Reactome
- apoptotic process Source: UniProtKB-KW
- cell cycle Source: UniProtKB-KW
- Fc-epsilon receptor signaling pathway Source: Reactome
- interleukin-1-mediated signaling pathway Source: Reactome
- MAPK cascade Source: Reactome
- negative regulation of canonical Wnt signaling pathway Source: Reactome
- negative regulation of extrinsic apoptotic signaling pathway Source: UniProtKB
- negative regulation of G2/M transition of mitotic cell cycle Source: Reactome
- NIK/NF-kappaB signaling Source: Reactome
- positive regulation of canonical Wnt signaling pathway Source: Reactome
- positive regulation of endopeptidase activity Source: GO_Central
- post-translational protein modification Source: Reactome
- proteasome-mediated ubiquitin-dependent protein catabolic process Source: Reactome
- protein deubiquitination Source: Reactome
- protein polyubiquitination Source: Reactome
- regulation of cellular amino acid metabolic process Source: Reactome
- regulation of G1/S transition of mitotic cell cycle Source: GO_Central
- regulation of hematopoietic stem cell differentiation Source: Reactome
- regulation of mitotic cell cycle phase transition Source: Reactome
- regulation of mRNA stability Source: Reactome
- regulation of proteasomal protein catabolic process Source: UniProtKB
- regulation of transcription from RNA polymerase II promoter in response to hypoxia Source: Reactome
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Source: Reactome
- stimulatory C-type lectin receptor signaling pathway Source: Reactome
- T cell receptor signaling pathway Source: Reactome
- transmembrane transport Source: Reactome
- tumor necrosis factor-mediated signaling pathway Source: Reactome
- viral process Source: UniProtKB-KW
- Wnt signaling pathway, planar cell polarity pathway Source: Reactome
Keywordsi
Biological process | Apoptosis, Cell cycle, Host-virus interaction |
Enzyme and pathway databases
PathwayCommonsi | P61289 |
Reactomei | R-HSA-1169091, Activation of NF-kappaB in B cells R-HSA-1234176, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1236974, ER-Phagosome pathway R-HSA-1236978, Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-174084, Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174113, SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174154, APC/C:Cdc20 mediated degradation of Securin R-HSA-174178, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174184, Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-180534, Vpu mediated degradation of CD4 R-HSA-180585, Vif-mediated degradation of APOBEC3G R-HSA-187577, SCF(Skp2)-mediated degradation of p27/p21 R-HSA-195253, Degradation of beta-catenin by the destruction complex R-HSA-202424, Downstream TCR signaling R-HSA-211733, Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-2467813, Separation of Sister Chromatids R-HSA-2871837, FCERI mediated NF-kB activation R-HSA-349425, Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-350562, Regulation of ornithine decarboxylase (ODC) R-HSA-382556, ABC-family proteins mediated transport R-HSA-450408, AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-4608870, Asymmetric localization of PCP proteins R-HSA-4641257, Degradation of AXIN R-HSA-4641258, Degradation of DVL R-HSA-5358346, Hedgehog ligand biogenesis R-HSA-5362768, Hh mutants that don't undergo autocatalytic processing are degraded by ERAD R-HSA-5607761, Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607764, CLEC7A (Dectin-1) signaling R-HSA-5610780, Degradation of GLI1 by the proteasome R-HSA-5610783, Degradation of GLI2 by the proteasome R-HSA-5610785, GLI3 is processed to GLI3R by the proteasome R-HSA-5632684, Hedgehog 'on' state R-HSA-5658442, Regulation of RAS by GAPs R-HSA-5668541, TNFR2 non-canonical NF-kB pathway R-HSA-5676590, NIK-->noncanonical NF-kB signaling R-HSA-5678895, Defective CFTR causes cystic fibrosis R-HSA-5687128, MAPK6/MAPK4 signaling R-HSA-5689603, UCH proteinases R-HSA-5689880, Ub-specific processing proteases R-HSA-68827, CDT1 association with the CDC6:ORC:origin complex R-HSA-68949, Orc1 removal from chromatin R-HSA-69017, CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69481, G2/M Checkpoints R-HSA-69601, Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-75815, Ubiquitin-dependent degradation of Cyclin D R-HSA-8852276, The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8854050, FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8939236, RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939902, Regulation of RUNX2 expression and activity R-HSA-8941858, Regulation of RUNX3 expression and activity R-HSA-8948751, Regulation of PTEN stability and activity R-HSA-8951664, Neddylation R-HSA-9010553, Regulation of expression of SLITs and ROBOs R-HSA-9020702, Interleukin-1 signaling R-HSA-9604323, Negative regulation of NOTCH4 signaling R-HSA-983168, Antigen processing: Ubiquitination & Proteasome degradation |
Names & Taxonomyi
Protein namesi | Recommended name: Proteasome activator complex subunit 3Alternative name(s): 11S regulator complex subunit gamma Short name: REG-gamma Activator of multicatalytic protease subunit 3 Ki nuclear autoantigen Proteasome activator 28 subunit gamma Short name: PA28g Short name: PA28gamma |
Gene namesi | Name:PSME3 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000131467.10 |
HGNCi | HGNC:9570, PSME3 |
MIMi | 605129, gene |
neXtProti | NX_P61289 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Nucleus
- nucleoplasm Source: HPA
- nucleus Source: UniProtKB
Other locations
- cytoplasm Source: GO_Central
- membrane Source: UniProtKB
- proteasome activator complex Source: InterPro
- proteasome complex Source: ProtInc
Keywords - Cellular componenti
Cytoplasm, Nucleus, ProteasomePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 188 | K → E, D, A, C, N, Q, H, F, S, I or P: Assembles into less stable hexamers/heptamers and therefore impairs specificity of activation of trypsin-like subunits of the proteasome. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 10197 |
OpenTargetsi | ENSG00000131467 |
PharmGKBi | PA33916 |
Miscellaneous databases
Pharosi | P61289, Tbio |
Chemistry databases
ChEMBLi | CHEMBL4296023 |
Polymorphism and mutation databases
BioMutai | PSME3 |
DMDMi | 47117724 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedCombined sources1 Publication | |||
ChainiPRO_0000161789 | 2 – 254 | Proteasome activator complex subunit 3Add BLAST | 253 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylalanineCombined sources1 Publication | 1 | |
Modified residuei | 17 | PhosphoserineCombined sources | 1 | |
Modified residuei | 24 | PhosphoserineCombined sources | 1 | |
Modified residuei | 195 | N6-acetyllysine; by P300/CBP1 Publication | 1 | |
Modified residuei | 247 | Phosphoserine; by CHEK21 Publication | 1 |
Post-translational modificationi
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | P61289 |
jPOSTi | P61289 |
MassIVEi | P61289 |
PaxDbi | P61289 |
PeptideAtlasi | P61289 |
PRIDEi | P61289 |
ProteomicsDBi | 57290 57291 [P61289-2] |
PTM databases
iPTMneti | P61289 |
PhosphoSitePlusi | P61289 |
SwissPalmi | P61289 |
Expressioni
Inductioni
Gene expression databases
Bgeei | ENSG00000131467, Expressed in tonsil and 240 other tissues |
ExpressionAtlasi | P61289, baseline and differential |
Genevisiblei | P61289, HS |
Organism-specific databases
HPAi | ENSG00000131467, Low tissue specificity |
Interactioni
Subunit structurei
Homoheptamer; the stability of the heptamer is essential for the specific activation of the trypsine-like subunit and inhibition of the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits of the proteasome.
Interacts with p53/TP53 and MDM2.
Interacts with MAP3K3 (By similarity). Associates with the proteasome.
Interacts with CCAR2.
Interacts with PSME3IP1 (via C-terminus); the interaction is direct and promotes the association of PSME3 with the 20S proteasome (PubMed:29934401).
Interacts with COIL; the interaction is inhibited by PSME3IP1 (PubMed:29934401).
By similarity8 Publications(Microbial infection) Interacts with human cytomegalovirus UL27.
1 PublicationBinary interactionsi
Hide detailsP61289
GO - Molecular functioni
- identical protein binding Source: IntAct
- MDM2/MDM4 family protein binding Source: UniProtKB
- p53 binding Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 115492, 276 interactors |
CORUMi | P61289 |
IntActi | P61289, 145 interactors |
MINTi | P61289 |
STRINGi | 9606.ENSP00000293362 |
Miscellaneous databases
RNActi | P61289, protein |
Family & Domainsi
Domaini
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG4470, Eukaryota |
GeneTreei | ENSGT00950000183098 |
InParanoidi | P61289 |
OMAi | PCNKPLC |
OrthoDBi | 1251022at2759 |
PhylomeDBi | P61289 |
TreeFami | TF106236 |
Family and domain databases
Gene3Di | 1.20.120.180, 1 hit 1.20.5.120, 1 hit |
InterProi | View protein in InterPro IPR003186, PA28_C IPR036997, PA28_C_sf IPR036996, PA28_N_sf IPR009077, Proteasome_activ_PA28 IPR003185, Proteasome_activ_PA28_N IPR036252, Proteasome_activ_sf |
PANTHERi | PTHR10660, PTHR10660, 1 hit |
Pfami | View protein in Pfam PF02251, PA28_alpha, 1 hit PF02252, PA28_beta, 1 hit |
SUPFAMi | SSF47216, SSF47216, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 10 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MASLLKVDQE VKLKVDSFRE RITSEAEDLV ANFFPKKLLE LDSFLKEPIL
60 70 80 90 100
NIHDLTQIHS DMNLPVPDPI LLTNSHDGLD GPTYKKRRLD ECEEAFQGTK
110 120 130 140 150
VFVMPNGMLK SNQQLVDIIE KVKPEIRLLI EKCNTVKMWV QLLIPRIEDG
160 170 180 190 200
NNFGVSIQEE TVAELRTVES EAASYLDQIS RYYITRAKLV SKIAKYPHVE
210 220 230 240 250
DYRRTVTEID EKEYISLRLI ISELRNQYVT LHDMILKNIE KIKRPRSSNA
ETLY
Computationally mapped potential isoform sequencesi
There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketK7ENH2 | K7ENH2_HUMAN | Proteasome activator complex subuni... | PSME3 | 179 | Annotation score: | ||
K9J957 | K9J957_HUMAN | Proteasome activator complex subuni... | PSME3 | 231 | Annotation score: | ||
B3KQ25 | B3KQ25_HUMAN | Proteasome activator complex subuni... | PSME3 | 193 | Annotation score: | ||
K7ESG5 | K7ESG5_HUMAN | Proteasome activator complex subuni... | PSME3 | 198 | Annotation score: | ||
K7EKR3 | K7EKR3_HUMAN | Proteasome activator complex subuni... | PSME3 | 118 | Annotation score: | ||
K7EMD0 | K7EMD0_HUMAN | Proteasome activator complex subuni... | PSME3 | 96 | Annotation score: | ||
A0A087WTV2 | A0A087WTV2_HUMAN | Proteasome activator complex subuni... | PSME3 | 170 | Annotation score: | ||
K7EPX6 | K7EPX6_HUMAN | Proteasome activator complex subuni... | PSME3 | 110 | Annotation score: | ||
K7EJF8 | K7EJF8_HUMAN | Proteasome activator complex subuni... | PSME3 | 42 | Annotation score: | ||
B7Z8D3 | B7Z8D3_HUMAN | Proteasome activator complex subuni... | PSME3 | 130 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 25 | E → K in AAB60335 (PubMed:7951316).Curated | 1 | |
Sequence conflicti | 94 | E → K in AAA93227 (PubMed:7545954).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_055047 | 1 – 13 | MASLL…QEVKL → MEKWILKKIKYLQSGGLSAS YYSY in isoform 3. CuratedAdd BLAST | 13 | |
Alternative sequenceiVSP_004516 | 135 | T → TPSGKGPHICFDLQ in isoform 2. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U11292 mRNA Translation: AAB60335.1 BT019386 mRNA Translation: AAV38193.1 AK292618 mRNA Translation: BAF85307.1 AK074999 mRNA Translation: BAG52046.1 AC016889 Genomic DNA No translation available. CH471152 Genomic DNA Translation: EAW60893.1 BC001423 mRNA Translation: AAH01423.1 BC002684 mRNA Translation: AAH02684.1 BC008020 mRNA Translation: AAH08020.1 U25756 Genomic DNA Translation: AAA93227.1 |
CCDSi | CCDS11442.1 [P61289-2] CCDS45689.1 CCDS59290.1 [P61289-3] |
PIRi | I38702, A60537 |
RefSeqi | NP_005780.2, NM_005789.3 [P61289-1] NP_789839.1, NM_176863.2 [P61289-2] |
Genome annotation databases
Ensembli | ENST00000293362; ENSP00000293362; ENSG00000131467 [P61289-2] ENST00000441946; ENSP00000409487; ENSG00000131467 [P61289-3] ENST00000590720; ENSP00000466794; ENSG00000131467 [P61289-1] |
GeneIDi | 10197 |
KEGGi | hsa:10197 |
UCSCi | uc002ibq.5, human |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U11292 mRNA Translation: AAB60335.1 BT019386 mRNA Translation: AAV38193.1 AK292618 mRNA Translation: BAF85307.1 AK074999 mRNA Translation: BAG52046.1 AC016889 Genomic DNA No translation available. CH471152 Genomic DNA Translation: EAW60893.1 BC001423 mRNA Translation: AAH01423.1 BC002684 mRNA Translation: AAH02684.1 BC008020 mRNA Translation: AAH08020.1 U25756 Genomic DNA Translation: AAA93227.1 |
CCDSi | CCDS11442.1 [P61289-2] CCDS45689.1 CCDS59290.1 [P61289-3] |
PIRi | I38702, A60537 |
RefSeqi | NP_005780.2, NM_005789.3 [P61289-1] NP_789839.1, NM_176863.2 [P61289-2] |
3D structure databases
SMRi | P61289 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 115492, 276 interactors |
CORUMi | P61289 |
IntActi | P61289, 145 interactors |
MINTi | P61289 |
STRINGi | 9606.ENSP00000293362 |
Chemistry databases
ChEMBLi | CHEMBL4296023 |
PTM databases
iPTMneti | P61289 |
PhosphoSitePlusi | P61289 |
SwissPalmi | P61289 |
Polymorphism and mutation databases
BioMutai | PSME3 |
DMDMi | 47117724 |
Proteomic databases
EPDi | P61289 |
jPOSTi | P61289 |
MassIVEi | P61289 |
PaxDbi | P61289 |
PeptideAtlasi | P61289 |
PRIDEi | P61289 |
ProteomicsDBi | 57290 57291 [P61289-2] |
Protocols and materials databases
Antibodypediai | 1736, 323 antibodies |
DNASUi | 10197 |
Genome annotation databases
Ensembli | ENST00000293362; ENSP00000293362; ENSG00000131467 [P61289-2] ENST00000441946; ENSP00000409487; ENSG00000131467 [P61289-3] ENST00000590720; ENSP00000466794; ENSG00000131467 [P61289-1] |
GeneIDi | 10197 |
KEGGi | hsa:10197 |
UCSCi | uc002ibq.5, human |
Organism-specific databases
CTDi | 10197 |
DisGeNETi | 10197 |
EuPathDBi | HostDB:ENSG00000131467.10 |
GeneCardsi | PSME3 |
HGNCi | HGNC:9570, PSME3 |
HPAi | ENSG00000131467, Low tissue specificity |
MIMi | 605129, gene |
neXtProti | NX_P61289 |
OpenTargetsi | ENSG00000131467 |
PharmGKBi | PA33916 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG4470, Eukaryota |
GeneTreei | ENSGT00950000183098 |
InParanoidi | P61289 |
OMAi | PCNKPLC |
OrthoDBi | 1251022at2759 |
PhylomeDBi | P61289 |
TreeFami | TF106236 |
Enzyme and pathway databases
PathwayCommonsi | P61289 |
Reactomei | R-HSA-1169091, Activation of NF-kappaB in B cells R-HSA-1234176, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1236974, ER-Phagosome pathway R-HSA-1236978, Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-174084, Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174113, SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174154, APC/C:Cdc20 mediated degradation of Securin R-HSA-174178, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174184, Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-180534, Vpu mediated degradation of CD4 R-HSA-180585, Vif-mediated degradation of APOBEC3G R-HSA-187577, SCF(Skp2)-mediated degradation of p27/p21 R-HSA-195253, Degradation of beta-catenin by the destruction complex R-HSA-202424, Downstream TCR signaling R-HSA-211733, Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-2467813, Separation of Sister Chromatids R-HSA-2871837, FCERI mediated NF-kB activation R-HSA-349425, Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-350562, Regulation of ornithine decarboxylase (ODC) R-HSA-382556, ABC-family proteins mediated transport R-HSA-450408, AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-4608870, Asymmetric localization of PCP proteins R-HSA-4641257, Degradation of AXIN R-HSA-4641258, Degradation of DVL R-HSA-5358346, Hedgehog ligand biogenesis R-HSA-5362768, Hh mutants that don't undergo autocatalytic processing are degraded by ERAD R-HSA-5607761, Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607764, CLEC7A (Dectin-1) signaling R-HSA-5610780, Degradation of GLI1 by the proteasome R-HSA-5610783, Degradation of GLI2 by the proteasome R-HSA-5610785, GLI3 is processed to GLI3R by the proteasome R-HSA-5632684, Hedgehog 'on' state R-HSA-5658442, Regulation of RAS by GAPs R-HSA-5668541, TNFR2 non-canonical NF-kB pathway R-HSA-5676590, NIK-->noncanonical NF-kB signaling R-HSA-5678895, Defective CFTR causes cystic fibrosis R-HSA-5687128, MAPK6/MAPK4 signaling R-HSA-5689603, UCH proteinases R-HSA-5689880, Ub-specific processing proteases R-HSA-68827, CDT1 association with the CDC6:ORC:origin complex R-HSA-68949, Orc1 removal from chromatin R-HSA-69017, CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69481, G2/M Checkpoints R-HSA-69601, Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-75815, Ubiquitin-dependent degradation of Cyclin D R-HSA-8852276, The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8854050, FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8939236, RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939902, Regulation of RUNX2 expression and activity R-HSA-8941858, Regulation of RUNX3 expression and activity R-HSA-8948751, Regulation of PTEN stability and activity R-HSA-8951664, Neddylation R-HSA-9010553, Regulation of expression of SLITs and ROBOs R-HSA-9020702, Interleukin-1 signaling R-HSA-9604323, Negative regulation of NOTCH4 signaling R-HSA-983168, Antigen processing: Ubiquitination & Proteasome degradation |
Miscellaneous databases
BioGRID-ORCSi | 10197, 71 hits in 859 CRISPR screens |
ChiTaRSi | PSME3, human |
GeneWikii | PSME3 |
GenomeRNAii | 10197 |
Pharosi | P61289, Tbio |
PROi | PR:P61289 |
RNActi | P61289, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000131467, Expressed in tonsil and 240 other tissues |
ExpressionAtlasi | P61289, baseline and differential |
Genevisiblei | P61289, HS |
Family and domain databases
Gene3Di | 1.20.120.180, 1 hit 1.20.5.120, 1 hit |
InterProi | View protein in InterPro IPR003186, PA28_C IPR036997, PA28_C_sf IPR036996, PA28_N_sf IPR009077, Proteasome_activ_PA28 IPR003185, Proteasome_activ_PA28_N IPR036252, Proteasome_activ_sf |
PANTHERi | PTHR10660, PTHR10660, 1 hit |
Pfami | View protein in Pfam PF02251, PA28_alpha, 1 hit PF02252, PA28_beta, 1 hit |
SUPFAMi | SSF47216, SSF47216, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PSME3_HUMAN | |
Accessioni | P61289Primary (citable) accession number: P61289 Secondary accession number(s): A8K9A3 Q9BQD9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 10, 2004 |
Last sequence update: | May 10, 2004 | |
Last modified: | December 2, 2020 | |
This is version 174 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families - Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM