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Protein

60S ribosomal protein L26

Gene

Rpl26

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the large ribosomal subunit.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L26
Alternative name(s):
Silica-induced gene 20 protein
Short name:
SIG-20
Gene namesi
Name:Rpl26
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:106022 Rpl26

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001307891 – 14560S ribosomal protein L26Add BLAST145

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki136Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei139PhosphothreonineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiP61255
PaxDbiP61255
PeptideAtlasiP61255
PRIDEiP61255
TopDownProteomicsiP61255

PTM databases

iPTMnetiP61255
PhosphoSitePlusiP61255

Expressioni

Inductioni

Up-regulated in silica-treated macrophages.1 Publication

Gene expression databases

BgeeiENSMUSG00000060938
CleanExiMM_RPL26
ExpressionAtlasiP61255 baseline and differential
GenevisibleiP61255 MM

Interactioni

Subunit structurei

Component of the large ribosomal subunit (Probable). Interacts with DHX33 (PubMed:26100019).1 Publication1 Publication

Protein-protein interaction databases

BioGridi202973, 4 interactors
CORUMiP61255
IntActiP61255, 6 interactors
MINTiP61255
STRINGi10090.ENSMUSP00000073175

Structurei

3D structure databases

ProteinModelPortaliP61255
SMRiP61255
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3401 Eukaryota
COG0198 LUCA
GeneTreeiENSGT00390000014165
HOGENOMiHOG000216571
HOVERGENiHBG017293
InParanoidiP61255
KOiK02898
OMAiVRIMRGD
OrthoDBiEOG091G0TZX
PhylomeDBiP61255
TreeFamiTF300236

Family and domain databases

Gene3Di2.30.30.30, 1 hit
HAMAPiMF_01326_A Ribosomal_L24_A, 1 hit
InterProiView protein in InterPro
IPR005824 KOW
IPR014722 Rib_L2_dom2
IPR005825 Ribosomal_L24/26_CS
IPR005756 Ribosomal_L26/L24P_euk/arc
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR11143 PTHR11143, 1 hit
PfamiView protein in Pfam
PF00467 KOW, 1 hit
PF16906 Ribosomal_L26, 1 hit
SMARTiView protein in SMART
SM00739 KOW, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
TIGRFAMsiTIGR01080 rplX_A_E, 1 hit
PROSITEiView protein in PROSITE
PS01108 RIBOSOMAL_L24, 1 hit

Sequencei

Sequence statusi: Complete.

P61255-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR
60 70 80 90 100
KDDEVQVVRG HYKGQQIGKV VQVYRKKYVI YIERVQREKA NGTTVHVGIH
110 120 130 140
PSKVVITRLK LDKDRKKILE RKAKSRQVGK EKGKYKEETI EKMQE
Length:145
Mass (Da):17,258
Last modified:May 10, 2004 - v1
Checksum:i049D53AB4E3F46B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X80699 mRNA Translation: CAA56716.1
BC070397 mRNA Translation: AAH70397.1
CCDSiCCDS36187.1
PIRiI48616 S48864
RefSeqiNP_033106.1, NM_009080.2
UniGeneiMm.306548
Mm.3229

Genome annotation databases

EnsembliENSMUST00000073471; ENSMUSP00000073175; ENSMUSG00000060938
ENSMUST00000167436; ENSMUSP00000129072; ENSMUSG00000060938
GeneIDi19941
KEGGimmu:19941
UCSCiuc007joh.1 mouse

Similar proteinsi

Entry informationi

Entry nameiRL26_MOUSE
AccessioniPrimary (citable) accession number: P61255
Secondary accession number(s): Q02877
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: May 10, 2004
Last modified: July 18, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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