UniProtKB - P61175 (RL22_ECOLI)
Protein
50S ribosomal protein L22
Gene
rplV
Organism
Escherichia coli (strain K12)
Status
Functioni
This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.1 Publication
The globular domain of the protein is one of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that penetrates into the center of the 70S ribosome where it lines the wall of the exit tunnel. Removal of most of this hairpin (residues 85-95) does not prevent its incorporation into 70S ribosomes. Two of the hairpin residues (91 and 93) seem to be involved in translation elongation arrest of the SecM protein, as their replacement by larger amino acids alleviates the arrest.2 Publications
Miscellaneous
The wild-type allele (erythromycin sensitive) is dominant over the resistant allele, and is also dominant over the temperature-sensitive allele at both low and high temperatures.
GO - Molecular functioni
- rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: GO_Central
GO - Biological processi
- response to antibiotic Source: UniProtKB-KW
- ribosome assembly Source: CAFA
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Biological process | Antibiotic resistance |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10882-MONOMER MetaCyc:EG10882-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L22Alternative name(s): Large ribosomal subunit protein uL221 Publication |
Gene namesi | Name:rplV Synonyms:eryB Ordered Locus Names:b3315, JW3277 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
GO - Cellular componenti
- cytosol Source: EcoCyc
- cytosolic large ribosomal subunit Source: EcoCyc
- large ribosomal subunit Source: CAFA
- polysomal ribosome Source: CAFA
Pathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 82 – 99 | Missing : Incorporated into ribosomes in vivo, but is easily removed by a salt wash. 1 PublicationAdd BLAST | 18 | |
Mutagenesisi | 85 – 95 | Missing : Incorporates into ribosomes in vivo. 1 PublicationAdd BLAST | 11 | |
Mutagenesisi | 91 | G → A, D or S: Abolishes translation elongation arrest of SecM. 1 Publication | 1 | |
Mutagenesisi | 93 | A → S, T or V: Abolishes translation elongation arrest of SecM. 1 Publication | 1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000125153 | 1 – 110 | 50S ribosomal protein L22Add BLAST | 110 |
Proteomic databases
jPOSTi | P61175 |
PaxDbi | P61175 |
PRIDEi | P61175 |
Interactioni
Subunit structurei
Part of the 50S ribosomal subunit.
10 PublicationsBinary interactionsi
P61175
With | #Exp. | IntAct |
---|---|---|
ubiG [P17993] | 3 | EBI-542255,EBI-559367 |
Protein-protein interaction databases
BioGRIDi | 852125, 1 interactor |
ComplexPortali | CPX-3807, 50S large ribosomal subunit |
DIPi | DIP-35983N |
IntActi | P61175, 132 interactors |
STRINGi | 511145.b3315 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P61175 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P61175 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL22 family.Curated
Phylogenomic databases
eggNOGi | COG0091, Bacteria |
HOGENOMi | CLU_083987_3_3_6 |
InParanoidi | P61175 |
PhylomeDBi | P61175 |
Family and domain databases
CDDi | cd00336, Ribosomal_L22, 1 hit |
Gene3Di | 3.90.470.10, 1 hit |
HAMAPi | MF_01331_B, Ribosomal_L22_B, 1 hit |
InterProi | View protein in InterPro IPR001063, Ribosomal_L22 IPR018260, Ribosomal_L22/L17_CS IPR036394, Ribosomal_L22/L17_sf IPR005727, Ribosomal_L22_bac/chlpt-type |
PANTHERi | PTHR13501, PTHR13501, 1 hit |
Pfami | View protein in Pfam PF00237, Ribosomal_L22, 1 hit |
SUPFAMi | SSF54843, SSF54843, 1 hit |
TIGRFAMsi | TIGR01044, rplV_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00464, RIBOSOMAL_L22, 1 hit |
i Sequence
Sequence statusi: Complete.
P61175-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
METIAKHRHA RSSAQKVRLV ADLIRGKKVS QALDILTYTN KKAAVLVKKV
60 70 80 90 100
LESAIANAEH NDGADIDDLK VTKIFVDEGP SMKRIMPRAK GRADRILKRT
110
SHITVVVSDR
Mass spectrometryi
Molecular mass is 12225.3 Da. Determined by MALDI. 1 Publication
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural varianti | 8 | R → C in strain: SK1048; decreases translational rate, tRNA binding and subunit association at 44 degrees Celsius; does not alter 23S rRNA or L4 interactions; not erythromycin resistant. 1 Publication | 1 | |
Natural varianti | 82 – 84 | Missing in strain: N281; confers erythromycin resistance; ribosomes bind erythromycin normally and have normal peptidyltransferase activity; 50S subunits assemble normally, even in the presence of drug; the protein is incorporated into ribosomes in vivo; abolishes translation elongation arrest of SecM. 2 Publications | 3 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X02613 Genomic DNA Translation: CAA26465.1 U18997 Genomic DNA Translation: AAA58112.1 U00096 Genomic DNA Translation: AAC76340.1 AP009048 Genomic DNA Translation: BAE77976.1 |
PIRi | G23129, R5EC22 |
RefSeqi | NP_417774.1, NC_000913.3 WP_000447529.1, NZ_STEB01000038.1 |
Genome annotation databases
EnsemblBacteriai | AAC76340; AAC76340; b3315 BAE77976; BAE77976; BAE77976 |
GeneIDi | 53886463 947813 |
KEGGi | ecj:JW3277 eco:b3315 |
PATRICi | fig|1411691.4.peg.3416 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X02613 Genomic DNA Translation: CAA26465.1 U18997 Genomic DNA Translation: AAA58112.1 U00096 Genomic DNA Translation: AAC76340.1 AP009048 Genomic DNA Translation: BAE77976.1 |
PIRi | G23129, R5EC22 |
RefSeqi | NP_417774.1, NC_000913.3 WP_000447529.1, NZ_STEB01000038.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2J28 | electron microscopy | 8.00 | S | 1-110 | [»] | |
2RDO | electron microscopy | 9.10 | S | 1-110 | [»] | |
3BBX | electron microscopy | 10.00 | S | 1-110 | [»] | |
3J5L | electron microscopy | 6.60 | S | 1-110 | [»] | |
3J7Z | electron microscopy | 3.90 | S | 1-110 | [»] | |
3J8G | electron microscopy | 5.00 | S | 1-110 | [»] | |
3J9Y | electron microscopy | 3.90 | S | 1-110 | [»] | |
3J9Z | electron microscopy | 3.60 | LQ | 1-110 | [»] | |
3JA1 | electron microscopy | 3.60 | LU | 1-110 | [»] | |
3JBU | electron microscopy | 3.64 | s | 1-110 | [»] | |
3JBV | electron microscopy | 3.32 | s | 1-110 | [»] | |
3JCD | electron microscopy | 3.70 | S | 1-110 | [»] | |
3JCE | electron microscopy | 3.20 | S | 1-110 | [»] | |
3JCJ | electron microscopy | 3.70 | R | 1-110 | [»] | |
3JCN | electron microscopy | 4.60 | S | 1-110 | [»] | |
4CSU | electron microscopy | 5.50 | S | 1-110 | [»] | |
4U1U | X-ray | 2.95 | BS/DS | 1-110 | [»] | |
4U1V | X-ray | 3.00 | BS/DS | 1-110 | [»] | |
4U20 | X-ray | 2.90 | BS/DS | 1-110 | [»] | |
4U24 | X-ray | 2.90 | BS/DS | 1-110 | [»] | |
4U25 | X-ray | 2.90 | BS/DS | 1-110 | [»] | |
4U26 | X-ray | 2.80 | BS/DS | 1-110 | [»] | |
4U27 | X-ray | 2.80 | BS/DS | 1-110 | [»] | |
4UY8 | electron microscopy | 3.80 | S | 1-110 | [»] | |
4V47 | electron microscopy | 12.30 | AQ | 1-110 | [»] | |
4V48 | electron microscopy | 11.50 | AQ | 1-110 | [»] | |
4V4H | X-ray | 3.46 | BS/DS | 1-110 | [»] | |
4V4Q | X-ray | 3.46 | BS/DS | 1-110 | [»] | |
4V4V | electron microscopy | 15.00 | BQ | 5-110 | [»] | |
4V4W | electron microscopy | 15.00 | BQ | 5-110 | [»] | |
4V50 | X-ray | 3.22 | BS/DS | 1-110 | [»] | |
4V52 | X-ray | 3.21 | BS/DS | 1-110 | [»] | |
4V53 | X-ray | 3.54 | BS/DS | 1-110 | [»] | |
4V54 | X-ray | 3.30 | BS/DS | 1-110 | [»] | |
4V55 | X-ray | 4.00 | BS/DS | 1-110 | [»] | |
4V56 | X-ray | 3.93 | BS/DS | 1-110 | [»] | |
4V57 | X-ray | 3.50 | BS/DS | 1-110 | [»] | |
4V5B | X-ray | 3.74 | AS/CS | 1-110 | [»] | |
4V5H | electron microscopy | 5.80 | BS | 1-110 | [»] | |
4V5Y | X-ray | 4.45 | BS/DS | 1-110 | [»] | |
4V64 | X-ray | 3.50 | BS/DS | 1-110 | [»] | |
4V65 | electron microscopy | 9.00 | BL | 1-110 | [»] | |
4V66 | electron microscopy | 9.00 | BL | 1-110 | [»] | |
4V69 | electron microscopy | 6.70 | BS | 1-110 | [»] | |
4V6C | X-ray | 3.19 | BS/DS | 1-110 | [»] | |
4V6D | X-ray | 3.81 | BS/DS | 1-110 | [»] | |
4V6E | X-ray | 3.71 | BS/DS | 1-110 | [»] | |
4V6K | electron microscopy | 8.25 | AT | 1-110 | [»] | |
4V6L | electron microscopy | 13.20 | BT | 1-110 | [»] | |
4V6M | electron microscopy | 7.10 | BS | 1-110 | [»] | |
4V6N | electron microscopy | 12.10 | AU | 1-110 | [»] | |
4V6O | electron microscopy | 14.70 | BU | 1-110 | [»] | |
4V6P | electron microscopy | 13.50 | BU | 1-110 | [»] | |
4V6Q | electron microscopy | 11.50 | BU | 1-110 | [»] | |
4V6R | electron microscopy | 11.50 | BU | 1-110 | [»] | |
4V6S | electron microscopy | 13.10 | AU | 1-110 | [»] | |
4V6T | electron microscopy | 8.30 | BS | 1-110 | [»] | |
4V6V | electron microscopy | 9.80 | BW | 1-110 | [»] | |
4V6Y | electron microscopy | 12.00 | BS | 1-110 | [»] | |
4V6Z | electron microscopy | 12.00 | BS | 1-110 | [»] | |
4V70 | electron microscopy | 17.00 | BS | 1-110 | [»] | |
4V71 | electron microscopy | 20.00 | BS | 1-110 | [»] | |
4V72 | electron microscopy | 13.00 | BS | 1-110 | [»] | |
4V73 | electron microscopy | 15.00 | BS | 1-110 | [»] | |
4V74 | electron microscopy | 17.00 | BS | 1-110 | [»] | |
4V75 | electron microscopy | 12.00 | BS | 1-110 | [»] | |
4V76 | electron microscopy | 17.00 | BS | 1-110 | [»] | |
4V77 | electron microscopy | 17.00 | BS | 1-110 | [»] | |
4V78 | electron microscopy | 20.00 | BS | 1-110 | [»] | |
4V79 | electron microscopy | 15.00 | BS | 1-110 | [»] | |
4V7A | electron microscopy | 9.00 | BS | 1-110 | [»] | |
4V7B | electron microscopy | 6.80 | BS | 1-110 | [»] | |
4V7C | electron microscopy | 7.60 | BU | 1-110 | [»] | |
4V7D | electron microscopy | 7.60 | AV | 1-110 | [»] | |
4V7I | electron microscopy | 9.60 | AS | 1-110 | [»] | |
4V7S | X-ray | 3.25 | BS/DS | 1-110 | [»] | |
4V7T | X-ray | 3.19 | BS/DS | 1-110 | [»] | |
4V7U | X-ray | 3.10 | BS/DS | 1-110 | [»] | |
4V7V | X-ray | 3.29 | BS/DS | 1-110 | [»] | |
4V85 | X-ray | 3.20 | BW | 1-110 | [»] | |
4V89 | X-ray | 3.70 | BW | 1-110 | [»] | |
4V9C | X-ray | 3.30 | BS/DS | 1-110 | [»] | |
4V9D | X-ray | 3.00 | CS/DS | 1-110 | [»] | |
4V9O | X-ray | 2.90 | AS/CS/ES/GS | 1-110 | [»] | |
4V9P | X-ray | 2.90 | AS/CS/ES/GS | 1-110 | [»] | |
4WF1 | X-ray | 3.09 | BS/DS | 1-110 | [»] | |
4WOI | X-ray | 3.00 | BS/CS | 1-110 | [»] | |
4WWW | X-ray | 3.10 | RS/YS | 1-110 | [»] | |
4YBB | X-ray | 2.10 | CT/DT | 1-110 | [»] | |
5ADY | electron microscopy | 4.50 | S | 1-110 | [»] | |
5AFI | electron microscopy | 2.90 | S | 1-110 | [»] | |
5AKA | electron microscopy | 5.70 | S | 1-110 | [»] | |
5GAD | electron microscopy | 3.70 | T | 1-110 | [»] | |
5GAE | electron microscopy | 3.33 | T | 1-110 | [»] | |
5GAF | electron microscopy | 4.30 | T | 1-110 | [»] | |
5GAG | electron microscopy | 3.80 | T | 1-110 | [»] | |
5GAH | electron microscopy | 3.80 | T | 1-110 | [»] | |
5H5U | electron microscopy | 3.00 | T | 1-110 | [»] | |
5IQR | electron microscopy | 3.00 | S | 1-110 | [»] | |
5IT8 | X-ray | 3.12 | CT/DT | 1-110 | [»] | |
5J5B | X-ray | 2.80 | CT/DT | 1-110 | [»] | |
5J7L | X-ray | 3.00 | CT/DT | 1-110 | [»] | |
5J88 | X-ray | 3.32 | CT/DT | 1-110 | [»] | |
5J8A | X-ray | 3.10 | CT/DT | 1-110 | [»] | |
5J91 | X-ray | 2.96 | CT/DT | 1-110 | [»] | |
5JC9 | X-ray | 3.03 | CT/DT | 1-110 | [»] | |
5JTE | electron microscopy | 3.60 | BS | 1-110 | [»] | |
5JU8 | electron microscopy | 3.60 | BS | 1-110 | [»] | |
5KCR | electron microscopy | 3.60 | 1W | 1-110 | [»] | |
5KCS | electron microscopy | 3.90 | 1W | 1-110 | [»] | |
5KPS | electron microscopy | 3.90 | S | 1-110 | [»] | |
5KPV | electron microscopy | 4.10 | R | 1-110 | [»] | |
5KPW | electron microscopy | 3.90 | R | 1-110 | [»] | |
5KPX | electron microscopy | 3.90 | R | 1-110 | [»] | |
5L3P | electron microscopy | 3.70 | W | 1-110 | [»] | |
5LZA | electron microscopy | 3.60 | S | 1-110 | [»] | |
5LZB | electron microscopy | 5.30 | S | 1-110 | [»] | |
5LZC | electron microscopy | 4.80 | S | 1-110 | [»] | |
5LZD | electron microscopy | 3.40 | S | 1-110 | [»] | |
5LZE | electron microscopy | 3.50 | S | 1-110 | [»] | |
5LZF | electron microscopy | 4.60 | S | 1-110 | [»] | |
5MDV | electron microscopy | 2.97 | S | 1-110 | [»] | |
5MDW | electron microscopy | 3.06 | S | 1-110 | [»] | |
5MDY | electron microscopy | 3.35 | S | 1-110 | [»] | |
5MDZ | electron microscopy | 3.10 | S | 1-110 | [»] | |
5MGP | electron microscopy | 3.10 | S | 1-110 | [»] | |
5NCO | electron microscopy | 4.80 | T | 1-110 | [»] | |
5NP6 | electron microscopy | 3.60 | q | 1-110 | [»] | |
5NWY | electron microscopy | 2.93 | f | 1-110 | [»] | |
5O2R | electron microscopy | 3.40 | S | 1-110 | [»] | |
5U4I | electron microscopy | 3.50 | T | 1-110 | [»] | |
5U9F | electron microscopy | 3.20 | 21 | 1-110 | [»] | |
5U9G | electron microscopy | 3.20 | 21 | 1-110 | [»] | |
5UYK | electron microscopy | 3.90 | 21 | 1-110 | [»] | |
5UYL | electron microscopy | 3.60 | 21 | 1-110 | [»] | |
5UYM | electron microscopy | 3.20 | 21 | 1-110 | [»] | |
5UYN | electron microscopy | 4.00 | 21 | 1-110 | [»] | |
5UYP | electron microscopy | 3.90 | 21 | 1-110 | [»] | |
5UYQ | electron microscopy | 3.80 | 21 | 1-110 | [»] | |
5WDT | electron microscopy | 3.00 | S | 1-109 | [»] | |
5WE4 | electron microscopy | 3.10 | S | 1-109 | [»] | |
5WE6 | electron microscopy | 3.40 | S | 1-109 | [»] | |
5WFK | electron microscopy | 3.40 | S | 1-109 | [»] | |
6BU8 | electron microscopy | 3.50 | 21 | 1-110 | [»] | |
6BY1 | X-ray | 3.94 | CS/DS | 1-110 | [»] | |
6C4I | electron microscopy | 3.24 | T | 1-110 | [»] | |
6ENF | electron microscopy | 3.20 | S | 1-110 | [»] | |
6ENJ | electron microscopy | 3.70 | S | 1-110 | [»] | |
6ENU | electron microscopy | 3.10 | S | 1-110 | [»] | |
6GBZ | electron microscopy | 3.80 | S | 1-110 | [»] | |
6GC0 | electron microscopy | 3.80 | S | 1-110 | [»] | |
6GC4 | electron microscopy | 4.30 | S | 1-110 | [»] | |
6GC6 | electron microscopy | 4.30 | S | 1-110 | [»] | |
6GC7 | electron microscopy | 4.30 | S | 1-110 | [»] | |
6GC8 | electron microscopy | 3.80 | S | 1-110 | [»] | |
6GWT | electron microscopy | 3.80 | S | 1-110 | [»] | |
6GXM | electron microscopy | 3.80 | S | 1-110 | [»] | |
6GXN | electron microscopy | 3.90 | S | 1-110 | [»] | |
6GXO | electron microscopy | 3.90 | S | 1-110 | [»] | |
6GXP | electron microscopy | 4.40 | S | 1-110 | [»] | |
6H4N | electron microscopy | 3.00 | S | 1-110 | [»] | |
6H58 | electron microscopy | 7.90 | S/SS | 1-110 | [»] | |
6HRM | electron microscopy | 2.96 | S | 1-110 | [»] | |
6I0Y | electron microscopy | 3.20 | S | 1-110 | [»] | |
6I7V | X-ray | 2.90 | CT/DT | 1-110 | [»] | |
6O9J | electron microscopy | 3.90 | S | 1-110 | [»] | |
6O9K | electron microscopy | 4.00 | S | 1-110 | [»] | |
6OFX | electron microscopy | 3.30 | s | 1-110 | [»] | |
6OG7 | electron microscopy | 3.30 | s | 1-110 | [»] | |
6ORE | electron microscopy | 2.90 | S | 1-110 | [»] | |
6ORL | electron microscopy | 3.50 | S | 1-110 | [»] | |
6OST | electron microscopy | 4.20 | S | 1-110 | [»] | |
6OT3 | electron microscopy | 3.90 | S | 1-110 | [»] | |
6OUO | electron microscopy | 3.70 | S | 1-110 | [»] | |
6Q98 | electron microscopy | 4.30 | S | 1-110 | [»] | |
6Q9A | electron microscopy | 3.70 | S | 1-109 | [»] | |
6QDW | electron microscopy | 2.83 | s | 1-110 | [»] | |
6QUL | electron microscopy | 3.00 | T | 1-110 | [»] | |
6S0K | electron microscopy | 3.10 | T | 1-110 | [»] | |
6SZS | electron microscopy | 3.06 | S | 1-110 | [»] | |
6TBV | electron microscopy | 2.70 | L221 | 1-110 | [»] | |
6TC3 | electron microscopy | 2.70 | L221 | 1-110 | [»] | |
6VWL | electron microscopy | 3.10 | Q | 1-110 | [»] | |
6VWM | electron microscopy | 3.40 | Q | 1-110 | [»] | |
6VWN | electron microscopy | 3.40 | Q | 1-110 | [»] | |
6WD6 | electron microscopy | 3.70 | s | 1-110 | [»] | |
6WDB | electron microscopy | 4.00 | s | 1-110 | [»] | |
6WDC | electron microscopy | 4.20 | s | 1-110 | [»] | |
6WDD | electron microscopy | 3.20 | s | 1-110 | [»] | |
6WDE | electron microscopy | 3.00 | s | 1-110 | [»] | |
6WDF | electron microscopy | 3.30 | s | 1-110 | [»] | |
6WDG | electron microscopy | 3.30 | s | 1-110 | [»] | |
6WDH | electron microscopy | 4.30 | s | 1-110 | [»] | |
6WDI | electron microscopy | 4.00 | s | 1-110 | [»] | |
6WDJ | electron microscopy | 3.70 | s | 1-110 | [»] | |
6WDK | electron microscopy | 3.60 | s | 1-110 | [»] | |
6WDL | electron microscopy | 3.70 | s | 1-110 | [»] | |
6WDM | electron microscopy | 3.60 | s | 1-110 | [»] | |
6WNT | electron microscopy | 3.10 | s | 1-110 | [»] | |
6WNV | electron microscopy | 3.50 | s | 1-110 | [»] | |
6WNW | electron microscopy | 3.20 | s | 1-110 | [»] | |
6XZ7 | electron microscopy | 2.10 | S | 1-110 | [»] | |
6Y69 | electron microscopy | 2.86 | S | 1-110 | [»] | |
6YSR | electron microscopy | 3.10 | S | 1-110 | [»] | |
6YSS | electron microscopy | 2.60 | S | 1-110 | [»] | |
6YST | electron microscopy | 3.20 | S | 1-110 | [»] | |
6YSU | electron microscopy | 3.70 | S | 1-110 | [»] | |
7BV8 | electron microscopy | 3.14 | T | 1-110 | [»] | |
SMRi | P61175 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 852125, 1 interactor |
ComplexPortali | CPX-3807, 50S large ribosomal subunit |
DIPi | DIP-35983N |
IntActi | P61175, 132 interactors |
STRINGi | 511145.b3315 |
Proteomic databases
jPOSTi | P61175 |
PaxDbi | P61175 |
PRIDEi | P61175 |
Genome annotation databases
EnsemblBacteriai | AAC76340; AAC76340; b3315 BAE77976; BAE77976; BAE77976 |
GeneIDi | 53886463 947813 |
KEGGi | ecj:JW3277 eco:b3315 |
PATRICi | fig|1411691.4.peg.3416 |
Organism-specific databases
EchoBASEi | EB0875 |
Phylogenomic databases
eggNOGi | COG0091, Bacteria |
HOGENOMi | CLU_083987_3_3_6 |
InParanoidi | P61175 |
PhylomeDBi | P61175 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10882-MONOMER MetaCyc:EG10882-MONOMER |
Miscellaneous databases
EvolutionaryTracei | P61175 |
PROi | PR:P61175 |
Family and domain databases
CDDi | cd00336, Ribosomal_L22, 1 hit |
Gene3Di | 3.90.470.10, 1 hit |
HAMAPi | MF_01331_B, Ribosomal_L22_B, 1 hit |
InterProi | View protein in InterPro IPR001063, Ribosomal_L22 IPR018260, Ribosomal_L22/L17_CS IPR036394, Ribosomal_L22/L17_sf IPR005727, Ribosomal_L22_bac/chlpt-type |
PANTHERi | PTHR13501, PTHR13501, 1 hit |
Pfami | View protein in Pfam PF00237, Ribosomal_L22, 1 hit |
SUPFAMi | SSF54843, SSF54843, 1 hit |
TIGRFAMsi | TIGR01044, rplV_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00464, RIBOSOMAL_L22, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL22_ECOLI | |
Accessioni | P61175Primary (citable) accession number: P61175 Secondary accession number(s): P02423, Q2M6Y0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | July 21, 1986 | |
Last modified: | December 2, 2020 | |
This is version 170 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Ribosomal proteins
Ribosomal proteins families and list of entries