UniProtKB - P61032 (LNT_BDEBA)
Protein
Apolipoprotein N-acyltransferase
Gene
lnt
Organism
Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100)
Status
Functioni
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.UniRule annotation
Catalytic activityi
- a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 1-lyso-glycerophospholipid + H+ + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]UniRule annotationEC:2.3.1.269UniRule annotation
: lipoprotein biosynthesis (N-acyl transfer) Pathwayi
This protein is involved in the pathway lipoprotein biosynthesis (N-acyl transfer), which is part of Protein modification.UniRule annotationView all proteins of this organism that are known to be involved in the pathway lipoprotein biosynthesis (N-acyl transfer) and in Protein modification.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 294 | Proton acceptorUniRule annotation | 1 | |
Active sitei | 364 | UniRule annotation | 1 | |
Active sitei | 418 | NucleophileUniRule annotation | 1 |
GO - Molecular functioni
- N-acyltransferase activity Source: UniProtKB-UniRule
GO - Biological processi
- lipoprotein biosynthetic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | Acyltransferase, Transferase |
Enzyme and pathway databases
BioCyci | BBAC264462:BD_RS05805-MONOMER |
UniPathwayi | UPA00666 |
Names & Taxonomyi
Protein namesi | Recommended name: Apolipoprotein N-acyltransferaseUniRule annotation (EC:2.3.1.269UniRule annotation)Short name: ALP N-acyltransferaseUniRule annotation |
Gene namesi | Name:lntUniRule annotation Ordered Locus Names:Bd1278 |
Organismi | Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100) |
Taxonomic identifieri | 264462 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Oligoflexia › Bdellovibrionales › Bdellovibrionaceae › Bdellovibrio › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 31 – 51 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 71 – 91 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 106 – 126 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 180 – 200 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 210 – 230 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 515 – 535 | HelicalUniRule annotationAdd BLAST | 21 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000178044 | 1 – 547 | Apolipoprotein N-acyltransferaseAdd BLAST | 547 |
Proteomic databases
PRIDEi | P61032 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 247 – 515 | CN hydrolaseUniRule annotationAdd BLAST | 269 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG4105CE8 Bacteria COG0815 LUCA |
KOi | K03820 |
OMAi | PIGEFVP |
OrthoDBi | 1291198at2 |
Family and domain databases
CDDi | cd07571 ALP_N-acyl_transferase, 1 hit |
Gene3Di | 3.60.110.10, 1 hit |
HAMAPi | MF_01148 Lnt, 1 hit |
InterProi | View protein in InterPro IPR004563 Apolipo_AcylTrfase IPR003010 C-N_Hydrolase IPR036526 C-N_Hydrolase_sf |
Pfami | View protein in Pfam PF00795 CN_hydrolase, 1 hit |
SUPFAMi | SSF56317 SSF56317, 1 hit |
TIGRFAMsi | TIGR00546 lnt, 1 hit |
PROSITEi | View protein in PROSITE PS50263 CN_HYDROLASE, 1 hit |
i Sequence
Sequence statusi: Complete.
P61032-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDSLTLYVTN TMMKRWFQFF KHKAYDFRWA ILSGILVGTS YIPFPPWALI
60 70 80 90 100
FCYTPLWIYV TEESSSVKKS FWAGWVTQFI LTLIGFHWIA YTAHEFGQLP
110 120 130 140 150
WAVSYLALLL FCAFMHLYIP VAVAAGTWLR LRFKLSGGQT LFTIALLHAL
160 170 180 190 200
LERTWPVIFE WHLGYTLIWS KIPMYHLADL VGFHGLSAVV LLFNAWMGYV
210 220 230 240 250
WLKQSFVKKA LSHLSLLALT FAALVGWGFW HGKAWNKFDG ETKATVVQAN
260 270 280 290 300
IGNLEKIYAE QGRAYQEVIT RKFLDLSFAA MQKYPQTDIL IWPETAFPDY
310 320 330 340 350
LDQHLLDRKH AQILISGLQP LSRPLITGAY SKDPKADEKQ DTSTYNALFL
360 370 380 390 400
VDPLGNNLDK PYRKTELLAF GEYLPLSEQF PFLLKLLPFV SNFGRGHGPE
410 420 430 440 450
VMKWDTPQGS VRWGGQICYE GLYPSFTRGL AEKGADILVN VTNDSWFGKT
460 470 480 490 500
FEPQQHLYMT LARAIEVRRP LVRSTNTGVS TAVLANGDVL QKSPLHEEWS
510 520 530 540
GQFVIKYLKN APLTFFVQWG HWDWIVILLV LGAVIGRGAL NARSRRS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX842649 Genomic DNA Translation: CAE79175.1 |
RefSeqi | WP_011163777.1, NC_005363.1 |
Genome annotation databases
EnsemblBacteriai | CAE79175; CAE79175; Bd1278 |
KEGGi | bba:Bd1278 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX842649 Genomic DNA Translation: CAE79175.1 |
RefSeqi | WP_011163777.1, NC_005363.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 264462.Bd1278 |
Proteomic databases
PRIDEi | P61032 |
Genome annotation databases
EnsemblBacteriai | CAE79175; CAE79175; Bd1278 |
KEGGi | bba:Bd1278 |
Phylogenomic databases
eggNOGi | ENOG4105CE8 Bacteria COG0815 LUCA |
KOi | K03820 |
OMAi | PIGEFVP |
OrthoDBi | 1291198at2 |
Enzyme and pathway databases
UniPathwayi | UPA00666 |
BioCyci | BBAC264462:BD_RS05805-MONOMER |
Family and domain databases
CDDi | cd07571 ALP_N-acyl_transferase, 1 hit |
Gene3Di | 3.60.110.10, 1 hit |
HAMAPi | MF_01148 Lnt, 1 hit |
InterProi | View protein in InterPro IPR004563 Apolipo_AcylTrfase IPR003010 C-N_Hydrolase IPR036526 C-N_Hydrolase_sf |
Pfami | View protein in Pfam PF00795 CN_hydrolase, 1 hit |
SUPFAMi | SSF56317 SSF56317, 1 hit |
TIGRFAMsi | TIGR00546 lnt, 1 hit |
PROSITEi | View protein in PROSITE PS50263 CN_HYDROLASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | LNT_BDEBA | |
Accessioni | P61032Primary (citable) accession number: P61032 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 26, 2004 |
Last sequence update: | April 26, 2004 | |
Last modified: | May 8, 2019 | |
This is version 87 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - PATHWAY comments
Index of metabolic and biosynthesis pathways