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UniProtKB - P61024 (CKS1_HUMAN)

Entry version 157 (08 May 2019)
Sequence version 1 (26 Apr 2004)
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Protein

Cyclin-dependent kinases regulatory subunit 1

Gene

CKS1B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21
R-HSA-69231 Cyclin D associated events in G1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cyclin-dependent kinases regulatory subunit 1
Short name:
CKS-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CKS1B
Synonyms:CKS1
ORF Names:PNAS-143, PNAS-16
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:19083 CKS1B

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		116900 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P61024

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		1163

Open Targets

More...OpenTargetsi		ENSG00000173207

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38791

Chemistry databases

Drug and drug target database

More...DrugBanki		DB02681 Meta Vanadate

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CKS1B

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002062352 – 79Cyclin-dependent kinases regulatory subunit 1Add BLAST78

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P61024

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P61024

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P61024

PeptideAtlas

More...PeptideAtlasi		P61024

PRoteomics IDEntifications database

More...PRIDEi		P61024

ProteomicsDB human proteome resource

More...ProteomicsDBi		57254

Consortium for Top Down Proteomics

More...TopDownProteomicsi		P61024

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P61024

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P61024

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000173207 Expressed in 90 organ(s), highest expression level in female gonad

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P61024 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P61024 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA003424
HPA030762

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a homohexamer that can probably bind six kinase subunits.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		107582, 59 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		P61024

Database of interacting proteins

More...DIPi		DIP-102N

Protein interaction database and analysis system

More...IntActi		P61024, 60 interactors

Molecular INTeraction database

More...MINTi		P61024

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000311083

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

179
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BUHX-ray2.60B1-79[»]
1DKSX-ray3.20A/B1-79[»]
1DKTX-ray2.90A/B1-79[»]
2ASSX-ray3.00C5-73[»]
2ASTX-ray2.30C5-73[»]
4YC6X-ray2.60B/D/F/H1-79[»]

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P61024

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P61024

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CKS family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3484 Eukaryota
ENOG4111UAN LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00950000182971

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P61024

KEGG Orthology (KO)

More...KOi		K02219

Identification of Orthologs from Complete Genome Data

More...OMAi		SDDTHEY

Database of Orthologous Groups

More...OrthoDBi		1377855at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P61024

TreeFam database of animal gene trees

More...TreeFami		TF101142

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.170.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000789 Cyclin-dep_kinase_reg-sub
IPR036858 Cyclin-dep_kinase_reg-sub_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01111 CKS, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00296 CYCLINKINASE

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01084 CKS, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF55637 SSF55637, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00944 CKS_1, 1 hit
PS00945 CKS_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P61024-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ 
        60         70 
SQGWVHYMIH EPEPHILLFR RPLPKKPKK
Length:79
Mass (Da):9,660
Last modified:April 26, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE64207B140FA38D5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9BZU3Q9BZU3_HUMAN
Cyclin-dependent kinases regulatory...
CKS1B hCG_1739274
63Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5T179Q5T179_HUMAN
Cyclin-dependent kinases regulatory...
CKS1B
67Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X54941 mRNA Translation: CAA38702.1
AF274941 mRNA Translation: AAK07518.1
AF279897 mRNA Translation: AAK07553.1
BT007196 mRNA Translation: AAP35860.1
BC007751 mRNA Translation: AAH07751.1
BC015629 mRNA Translation: AAH15629.1
BC070319 mRNA Translation: AAH70319.1
BC070320 mRNA Translation: AAH70320.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS1077.1

Protein sequence database of the Protein Information Resource

More...PIRi		A36670

NCBI Reference Sequences

More...RefSeqi		NP_001817.1, NM_001826.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000308987; ENSP00000311083; ENSG00000173207

Database of genes from NCBI RefSeq genomes

More...GeneIDi		1163

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:1163

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54941 mRNA Translation: CAA38702.1
AF274941 mRNA Translation: AAK07518.1
AF279897 mRNA Translation: AAK07553.1
BT007196 mRNA Translation: AAP35860.1
BC007751 mRNA Translation: AAH07751.1
BC015629 mRNA Translation: AAH15629.1
BC070319 mRNA Translation: AAH70319.1
BC070320 mRNA Translation: AAH70320.1
CCDSiCCDS1077.1
PIRiA36670
RefSeqiNP_001817.1, NM_001826.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BUHX-ray2.60B1-79[»]
1DKSX-ray3.20A/B1-79[»]
1DKTX-ray2.90A/B1-79[»]
2ASSX-ray3.00C5-73[»]
2ASTX-ray2.30C5-73[»]
4YC6X-ray2.60B/D/F/H1-79[»]
SMRiP61024
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi107582, 59 interactors
CORUMiP61024
DIPiDIP-102N
IntActiP61024, 60 interactors
MINTiP61024
STRINGi9606.ENSP00000311083

Chemistry databases

DrugBankiDB02681 Meta Vanadate

PTM databases

iPTMnetiP61024
PhosphoSitePlusiP61024

Polymorphism and mutation databases

BioMutaiCKS1B

Proteomic databases

EPDiP61024
jPOSTiP61024
PaxDbiP61024
PeptideAtlasiP61024
PRIDEiP61024
ProteomicsDBi57254
TopDownProteomicsiP61024

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		1163
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000308987; ENSP00000311083; ENSG00000173207
GeneIDi1163
KEGGihsa:1163

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		1163
DisGeNETi1163

GeneCards: human genes, protein and diseases

More...GeneCardsi		CKS1B
HGNCiHGNC:19083 CKS1B
HPAiHPA003424
HPA030762
MIMi116900 gene
neXtProtiNX_P61024
OpenTargetsiENSG00000173207
PharmGKBiPA38791

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3484 Eukaryota
ENOG4111UAN LUCA
GeneTreeiENSGT00950000182971
InParanoidiP61024
KOiK02219
OMAiSDDTHEY
OrthoDBi1377855at2759
PhylomeDBiP61024
TreeFamiTF101142

Enzyme and pathway databases

ReactomeiR-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21
R-HSA-69231 Cyclin D associated events in G1

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CKS1B human
EvolutionaryTraceiP61024

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		CKS1B

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		1163

Protein Ontology

More...PROi		PR:P61024

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000173207 Expressed in 90 organ(s), highest expression level in female gonad
ExpressionAtlasiP61024 baseline and differential
GenevisibleiP61024 HS

Family and domain databases

Gene3Di3.30.170.10, 1 hit
InterProiView protein in InterPro
IPR000789 Cyclin-dep_kinase_reg-sub
IPR036858 Cyclin-dep_kinase_reg-sub_sf
PfamiView protein in Pfam
PF01111 CKS, 1 hit
PRINTSiPR00296 CYCLINKINASE
SMARTiView protein in SMART
SM01084 CKS, 1 hit
SUPFAMiSSF55637 SSF55637, 1 hit
PROSITEiView protein in PROSITE
PS00944 CKS_1, 1 hit
PS00945 CKS_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCKS1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P61024
Secondary accession number(s): P33551
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: April 26, 2004
Last modified: May 8, 2019
This is version 157 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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