rplX

Functionⁱ

One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. It is not thought to be involved in the functions of the mature 50S subunit in vitro.3 Publications

One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.2 Publications

GO - Molecular functionⁱ

rRNA binding Source: UniProtKB-KW
structural constituent of ribosome
Source: CAFA
Inferred from direct assayⁱ
- 3297162

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

ribosomal large subunit assembly
Source: CAFA
Inferred from direct assayⁱ
- 3297162
translation Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Molecular function

Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCycⁱ	EcoCyc:EG10884-MONOMER MetaCyc:EG10884-MONOMER

BioCycⁱ

EcoCyc:EG10884-MONOMER
MetaCyc:EG10884-MONOMER

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 50S ribosomal protein L24 Alternative name(s): Large ribosomal subunit protein uL241 Publication
Gene namesⁱ	Name:rplX Ordered Locus Names:b3309, JW3271
Organismⁱ	Escherichia coli (strain K12)
Taxonomic identifierⁱ	83333 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Proteomesⁱ	UP000000318 Componentⁱ: Chromosome UP000000625 Componentⁱ: Chromosome

Organism-specific databases

EcoGeneⁱ	EG10884 rplX

EcoGeneⁱ

EG10884 rplX

Subcellular locationⁱ

GO - Cellular componentⁱ

cytosol
Source: EcoCyc
Inferred from direct assayⁱ
- 18304323
cytosolic large ribosomal subunit
Source: CAFA
Inferred from direct assayⁱ
- 3297162

View the complete GO annotation on QuickGO ...

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Initiator methionineⁱ		Removed1 Publication
ChainⁱPRO_0000130654	2 – 104	50S ribosomal protein L24Add BLAST		103

Proteomic databases

EPDⁱ	P60624
PaxDbⁱ	P60624
PRIDEⁱ	P60624

Interactionⁱ

Subunit structureⁱ

Part of the 50S ribosomal subunit (PubMed:391595, PubMed:10094780, PubMed:12809609, PubMed:16272117, PubMed:25310980, PubMed:24844575, PubMed:27934701, PubMed:27906160, PubMed:27906161). Might contact the SecYEG translocation complex when it is docked with the ribosome.1 Publication9 Publications

Protein-protein interaction databases

Database of interacting proteins More...DIPⁱ	DIP-47846N
IntActⁱ	P60624, 61 interactors
STRINGⁱ	316385.ECDH10B_3484

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	10 – 13	Combined sources	4
Turnⁱ	17 – 20	Combined sources	4
Beta strandⁱ	22 – 28	Combined sources	7
Beta strandⁱ	32 – 36	Combined sources	5
Beta strandⁱ	40 – 45	Combined sources	6
Helixⁱ	51 – 53	Combined sources	3
Beta strandⁱ	57 – 62	Combined sources	6
Helixⁱ	67 – 69	Combined sources	3
Beta strandⁱ	70 – 74	Combined sources	5
Turnⁱ	75 – 78	Combined sources	4
Beta strandⁱ	79 – 81	Combined sources	3
Beta strandⁱ	83 – 88	Combined sources	6
Beta strandⁱ	91 – 96	Combined sources	6
Turnⁱ	97 – 100	Combined sources	4

Show more details

3D structure databases

ProteinModelPortalⁱ	P60624
SMRⁱ	P60624
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	P60624

EvolutionaryTraceⁱ

P60624

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the universal ribosomal protein uL24 family.Curated

Phylogenomic databases

eggNOGⁱ	ENOG4105KAR Bacteria COG0198 LUCA
HOGENOMⁱ	HOG000039892
InParanoidⁱ	P60624
KEGG Orthology (KO) More...KOⁱ	K02895
OMAⁱ	PQGGIVE
PhylomeDBⁱ	P60624

Family and domain databases

Gene3Dⁱ	2.30.30.30, 1 hit
HAMAPⁱ	MF_01326_B Ribosomal_L24_B, 1 hit
InterProⁱ	View protein in InterPro IPR005824 KOW IPR014722 Rib_L2_dom2 IPR003256 Ribosomal_L24 IPR005825 Ribosomal_L24/26_CS IPR008991 Translation_prot_SH3-like_sf
PANTHERⁱ	PTHR12903 PTHR12903, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00467 KOW, 1 hit PF17136 ribosomal_L24, 1 hit
SMARTⁱ	View protein in SMART SM00739 KOW, 1 hit
SUPFAMⁱ	SSF50104 SSF50104, 1 hit
TIGRFAMsⁱ	TIGR01079 rplX_bact, 1 hit
PROSITEⁱ	View protein in PROSITE PS01108 RIBOSOMAL_L24, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P60624-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAAKIRRDDE VIVLTGKDKG KRGKVKNVLS SGKVIVEGIN LVKKHQKPVP 
        60         70         80         90        100
ALNQPGGIVE KEAAIQVSNV AIFNAATGKA DRVGFRFEDG KKVRFFKSNS 

ETIK

Length:104

Mass (Da):11,316

Last modified:January 23, 2007 - v2

Checksum:ⁱ0ABF7DD305FA07F5

GO

Mass spectrometryⁱ

Molecular mass is 11186.5 Da from positions 2 - 104. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X01563 Genomic DNA Translation: CAA25716.1 U18997 Genomic DNA Translation: AAA58106.1 U00096 Genomic DNA Translation: AAC76334.1 AP009048 Genomic DNA Translation: BAE77982.1 M10195 Genomic DNA Translation: AAA24050.1
PIRⁱ	H65123 R5EC24
NCBI Reference Sequences More...RefSeqⁱ	NP_417768.1, NC_000913.3 WP_000729185.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaⁱ	AAC76334; AAC76334; b3309 BAE77982; BAE77982; BAE77982
GeneIDⁱ	29456670 947810
KEGGⁱ	ecj:JW3271 eco:b3309
PATRICⁱ	fig\|1411691.4.peg.3422

Protein	Similar proteins		Species	Score	Length	Source
P60624	50S ribosomal protein L24		CROS8		104	UniRef100_A7MPH5
50S ribosomal protein L24		ECO24		104
50S ribosomal protein L24		ECO55		104
50S ribosomal protein L24		ECO57		104
50S ribosomal protein L24		ECO5E		104
+297

Protein	Similar proteins		Species	Score	Length	Source
P60624	50S ribosomal protein L24		SHIFL		104	UniRef90_Q83PY8
50S ribosomal protein L24		CITK8		104
50S ribosomal protein L24		CROS8		104
50S ribosomal protein L24		ECO24		104
50S ribosomal protein L24		ECO55		104
+697

Protein	Similar proteins		Species	Score	Length	Source
P60624	50S ribosomal protein L24		SHIFL		104	UniRef50_Q83PY8
50S ribosomal protein L24		EDWI9		104
50S ribosomal protein L24		PECCP		104
50S ribosomal protein L24		YERP3		104
50S ribosomal protein L24		YERPA		104
+1119

Entry informationⁱ

Entry nameⁱ	RL24_ECOLI
Accessionⁱ	P60624Primary (citable) accession number: P60624 Secondary accession number(s): P02425, P37438, Q2M6X4
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
	Last sequence update:	January 23, 2007
	Last modified:	September 12, 2018
	This is version 156 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

UniProtKB - P60624 (RL24_ECOLI)

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50S ribosomal protein L24

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Molecule processing

Proteomic databases

Interactionⁱ

Subunit structureⁱ

Protein-protein interaction databases

Structureⁱ

Secondary structure

3D structure databases

Miscellaneous databases

Family & Domainsⁱ

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Mass spectrometryⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P60624 (RL24_ECOLI)

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50S ribosomal protein L24

rplX

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports information derived from mass spectrometry experiments done on the entire protein or on biologically active derived peptide(s).<p><a href='/help/mass_spectrometry' target='_top'>More...</a></p>Mass spectrometryi

Sequence databases

Genome annotation databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Mass spectrometryⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ