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UniProtKB - P60618 (RL15E_HALMA)

Entry version 118 (23 Feb 2022)
Sequence version 3 (23 Jan 2007)
Previous versions | rss
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Protein

50S ribosomal protein L15e

Gene

rpl15e

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
50S ribosomal protein L15e
Alternative name(s):
50S ribosomal protein LC12
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rpl15e
Ordered Locus Names:rrnAC2065
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri272569 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiArchaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Halobacteriales › Haloarculaceae › Haloarcula ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001169 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001275702 – 19650S ribosomal protein L15eAdd BLAST195

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the 50S ribosomal subunit.

Interacts with protein L7Ae and weakly with L44e.

2 Publications

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		P60618, 2 interactors

STRING: functional protein association networks

More...STRINGi		272569.rrnAC2065

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1196
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P60618

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P60618

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni72 – 93DisorderedSequence analysisAdd BLAST22
Regioni163 – 196DisorderedSequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi72 – 90Basic residuesSequence analysisAdd BLAST19

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eL15 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		arCOG04209, Archaea

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_080796_1_0_2

Identification of Orthologs from Complete Genome Data

More...OMAi		KYMQELY

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.1120.10, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_00256, Ribosomal_L15e, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR024794, Rbsml_L15e_core_dom_sf
IPR000439, Ribosomal_L15e
IPR020926, Ribosomal_L15e_arc
IPR020925, Ribosomal_L15e_CS
IPR012678, Ribosomal_L23/L15e_core_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR11847, PTHR11847, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00827, Ribosomal_L15e, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01384, Ribosomal_L15e, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54189, SSF54189, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01194, RIBOSOMAL_L15E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P60618-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARSAYSYIR DAWKNPGDGQ LAELQWQRQQ EWRNEGAVER IERPTRLDKA 
        60         70         80         90        100
RSQGYKAKQG VIVARVSVRK GSARKRRHKA GRRSKRQGVT RITRRKDIQR 
       110        120        130        140        150
VAEERASRTF PNLRVLNSYS VGQDGRQKWH EVILIDPNHP AIQNDDDLSW 
       160        170        180        190 
ICADDQADRV FRGLTGAGRR NRGLSGKGKG SEKTRPSLRS NGGKGK
Length:196
Mass (Da):22,355
Last modified:January 23, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i502449E0A6BC23BB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti13W → T AA sequence (PubMed:3196689).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY596297 Genomic DNA Translation: AAV46920.1

Protein sequence database of the Protein Information Resource

More...PIRi		H28949

NCBI Reference Sequences

More...RefSeqi		WP_004958369.1, NZ_CP039138.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAV46920; AAV46920; rrnAC2065

Database of genes from NCBI RefSeq genomes

More...GeneIDi		40152982
64821404

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hma:rrnAC2065

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|272569.17.peg.2714

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY596297 Genomic DNA Translation: AAV46920.1
PIRiH28949
RefSeqiWP_004958369.1, NZ_CP039138.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FFKX-ray2.40I37-194[»]
1JJ2X-ray2.40L2-194[»]
1K73X-ray3.01N2-194[»]
1K8AX-ray3.00N2-194[»]
1K9MX-ray3.00N2-194[»]
1KC8X-ray3.01N2-194[»]
1KD1X-ray3.00N2-194[»]
1KQSX-ray3.10L2-194[»]
1M1KX-ray3.20N2-194[»]
1M90X-ray2.80N2-194[»]
1N8RX-ray3.00N2-194[»]
1NJIX-ray3.00N2-194[»]
1Q7YX-ray3.20N2-194[»]
1Q81X-ray2.95N2-194[»]
1Q82X-ray2.98N2-194[»]
1Q86X-ray3.00N2-194[»]
1QVFX-ray3.10L2-194[»]
1QVGX-ray2.90L2-194[»]
1S72X-ray2.40M2-194[»]
1VQ4X-ray2.70M2-194[»]
1VQ5X-ray2.60M2-194[»]
1VQ6X-ray2.70M2-194[»]
1VQ7X-ray2.50M2-194[»]
1VQ8X-ray2.20M2-194[»]
1VQ9X-ray2.40M1-194[»]
1VQKX-ray2.30M1-194[»]
1VQLX-ray2.30M1-194[»]
1VQMX-ray2.30M1-194[»]
1VQNX-ray2.40M2-194[»]
1VQOX-ray2.20M1-194[»]
1VQPX-ray2.25M1-194[»]
1W2BX-ray3.50L2-194[»]
1YHQX-ray2.40M2-195[»]
1YI2X-ray2.65M1-195[»]
1YIJX-ray2.60M1-195[»]
1YITX-ray2.80M1-195[»]
1YJ9X-ray2.90M1-195[»]
1YJNX-ray3.00M1-195[»]
1YJWX-ray2.90M1-195[»]
2OTJX-ray2.90M2-194[»]
2OTLX-ray2.70M2-194[»]
2QA4X-ray3.00M1-194[»]
2QEXX-ray2.90M1-194[»]
3CC2X-ray2.40M1-196[»]
3CC4X-ray2.70M1-196[»]
3CC7X-ray2.70M1-196[»]
3CCEX-ray2.75M1-196[»]
3CCJX-ray2.70M1-196[»]
3CCLX-ray2.90M1-196[»]
3CCMX-ray2.55M1-196[»]
3CCQX-ray2.90M1-196[»]
3CCRX-ray3.00M1-196[»]
3CCSX-ray2.95M1-196[»]
3CCUX-ray2.80M1-196[»]
3CCVX-ray2.90M1-196[»]
3CD6X-ray2.75M1-196[»]
3CMAX-ray2.80M1-196[»]
3CMEX-ray2.95M1-196[»]
3CPWX-ray2.70L1-196[»]
3G4SX-ray3.20M2-195[»]
3G6EX-ray2.70M2-195[»]
3G71X-ray2.85M2-195[»]
3I55X-ray3.11M2-194[»]
3I56X-ray2.90M2-194[»]
4ADXelectron microscopy6.60M1-196[»]
4V9FX-ray2.40M1-196[»]
SMRiP60618
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

IntActiP60618, 2 interactors
STRINGi272569.rrnAC2065

Genome annotation databases

EnsemblBacteriaiAAV46920; AAV46920; rrnAC2065
GeneIDi40152982
64821404
KEGGihma:rrnAC2065
PATRICifig|272569.17.peg.2714

Phylogenomic databases

eggNOGiarCOG04209, Archaea
HOGENOMiCLU_080796_1_0_2
OMAiKYMQELY

Miscellaneous databases

EvolutionaryTraceiP60618

Family and domain databases

Gene3Di3.40.1120.10, 1 hit
HAMAPiMF_00256, Ribosomal_L15e, 1 hit
InterProiView protein in InterPro
IPR024794, Rbsml_L15e_core_dom_sf
IPR000439, Ribosomal_L15e
IPR020926, Ribosomal_L15e_arc
IPR020925, Ribosomal_L15e_CS
IPR012678, Ribosomal_L23/L15e_core_dom_sf
PANTHERiPTHR11847, PTHR11847, 1 hit
PfamiView protein in Pfam
PF00827, Ribosomal_L15e, 1 hit
SMARTiView protein in SMART
SM01384, Ribosomal_L15e, 1 hit
SUPFAMiSSF54189, SSF54189, 1 hit
PROSITEiView protein in PROSITE
PS01194, RIBOSOMAL_L15E, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL15E_HALMA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P60618
Secondary accession number(s): P12740, Q5V0N3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: January 23, 2007
Last modified: February 23, 2022
This is version 118 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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