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UniProtKB - P60412 (KR10B_HUMAN)

Entry version 122 (10 Feb 2021)
Sequence version 3 (18 May 2010)
Previous versions | rss
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Protein

Keratin-associated protein 10-11

Gene

KRTAP10-11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P60412

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-6805567, Keratinization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Keratin-associated protein 10-11
Alternative name(s):
High sulfur keratin-associated protein 10.11
Keratin-associated protein 10.11
Keratin-associated protein 18-11
Keratin-associated protein 18.11
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KRTAP10-11
Synonyms:KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:20528, KRTAP10-11

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P60412

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000243489.4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Keratin

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000243489

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134873081

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P60412, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		KRTAP10-11

Domain mapping of disease mutations (DMDM)

More...DMDMi		296439312

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001852191 – 298Keratin-associated protein 10-11Add BLAST298

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P60412

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P60412

PeptideAtlas

More...PeptideAtlasi		P60412

PRoteomics IDEntifications database

More...PRIDEi		P60412

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		57206

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000243489, Expressed in quadriceps femoris and 40 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P60412, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000243489, Tissue enriched (skin)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with hair keratins.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details
P60412
With#Exp.IntAct
ADAMTSL4 - isoform 3 [Q6UY14-3]3EBI-10217483,EBI-10173507
ANKS1A [Q49AR9]3EBI-10217483,EBI-11954519
C22orf39 [Q6P5X5]3EBI-10217483,EBI-7317823
CAMK2B [Q13554]3EBI-10217483,EBI-1058722
CATSPER1 [Q8NEC5]6EBI-10217483,EBI-744545
CREB5 - isoform 3 [Q02930-3]6EBI-10217483,EBI-10192698
CYSRT1 [A8MQ03]3EBI-10217483,EBI-3867333
FAM76B [Q5HYJ3]3EBI-10217483,EBI-751192
FAM76B - isoform 3 [Q5HYJ3-3]3EBI-10217483,EBI-11956087
FBXO34 [Q9NWN3]3EBI-10217483,EBI-719816
GLRX3 [O76003]4EBI-10217483,EBI-374781
HOXA1 [P49639]9EBI-10217483,EBI-740785
KRTAP1-1 [Q07627]3EBI-10217483,EBI-11959885
KRTAP10-8 [P60410]3EBI-10217483,EBI-10171774
KRTAP13-3 [Q3SY46]3EBI-10217483,EBI-10241252
KRTAP4-2 [Q9BYR5]3EBI-10217483,EBI-10172511
KRTAP5-9 [P26371]6EBI-10217483,EBI-3958099
KRTAP9-2 [Q9BYQ4]6EBI-10217483,EBI-1044640
KRTAP9-3 [Q9BYQ3]3EBI-10217483,EBI-1043191
LCE1B [Q5T7P3]3EBI-10217483,EBI-10245913
LCE1D [Q5T752]3EBI-10217483,EBI-11741311
LCE1E [Q5T753]3EBI-10217483,EBI-11955335
LCE3B [Q5TA77]3EBI-10217483,EBI-11974495
LCE3C [Q5T5A8]3EBI-10217483,EBI-10245291
MEOX2 [P50222]3EBI-10217483,EBI-748397
MEOX2 [Q6FHY5]3EBI-10217483,EBI-16439278
MOBP - isoform 3 [Q13875-3]3EBI-10217483,EBI-12013470
NOTCH2NLA [Q7Z3S9]3EBI-10217483,EBI-945833
OTX1 [P32242]6EBI-10217483,EBI-740446
PLSCR1 [O15162]3EBI-10217483,EBI-740019
POU4F2 [Q12837]3EBI-10217483,EBI-17236143
PRKAB2 [O43741]3EBI-10217483,EBI-1053424
PRKAG1 [P54619]5EBI-10217483,EBI-1181439
SMCP [P49901]3EBI-10217483,EBI-750494
SPATA3 [A0A024R4B0]3EBI-10217483,EBI-14123856
SPRY1 [O43609]3EBI-10217483,EBI-3866665
SPRY2 [O43597]3EBI-10217483,EBI-742487
TLE5 - isoform 2 [Q08117-2]3EBI-10217483,EBI-11741437
ZNF587 [Q96SQ5]3EBI-10217483,EBI-6427977

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		132129, 38 interactors

Protein interaction database and analysis system

More...IntActi		P60412, 38 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000334197

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P60412, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati26 – 3015
Repeati36 – 4025
Repeati57 – 6135
Repeati79 – 8345
Repeati89 – 9355
Repeati99 – 10365
Repeati104 – 10875
Repeati109 – 11385
Repeati114 – 11895
Repeati119 – 123105
Repeati126 – 130115
Repeati136 – 140125
Repeati146 – 150135
Repeati151 – 155145
Repeati156 – 160155
Repeati168 – 172165
Repeati178 – 182175
Repeati188 – 192185
Repeati193 – 197195
Repeati203 – 207205
Repeati225 – 229215
Repeati230 – 234225
Repeati249 – 253235
Repeati256 – 260245
Repeati267 – 271255

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni26 – 27125 X 5 AA repeats of C-C-X(3)Add BLAST246

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the KRTAP type 10 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4726, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000165026

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P60412

Identification of Orthologs from Complete Genome Data

More...OMAi		SECAGNC

Database of Orthologous Groups

More...OrthoDBi		1622331at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P60412

TreeFam database of animal gene trees

More...TreeFami		TF351356

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002494, KAP

The PANTHER Classification System

More...PANTHERi		PTHR23262, PTHR23262, 3 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13885, Keratin_B2_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P60412-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASTMSVCS SAYSDSWQVD DCPESCCEPP CSAPSCCAPA PSLSLVCTPV 
        60         70         80         90        100
SCVSSPCCQA ACEPSACQSG CTSSCTPSCC QQSSCQPACC TSSPCQQACC 
       110        120        130        140        150
VPVCCKTVCC KPVCCVPVCC GAASSCCRQS SCQPACCASS SCQPACCVPV 
       160        170        180        190        200
CCKPVCCVST CSEDSSSCCQ QSSCQPACCT SSSYQQACCV PVCCKTVYCK 
       210        220        230        240        250
PICCVPVCSR ASSSRCQQPS CQPACCTTSC CRPSSSVSLL CHPVCRSTCC 
       260        270        280        290 
VPVSSCCAPT SSCQSSCCRP ASCVSLLCRP ASSRLACYSL CSGKKSSC
Length:298
Mass (Da):30,243
Last modified:May 18, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i11A332F802EE9222
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti213S → Y in BAD01546 (PubMed:15028290).Curated1
Sequence conflicti269R → C in BAD01546 (PubMed:15028290).Curated1
Sequence conflicti269R → C in AAI31612 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_060056130S → F. Corresponds to variant dbSNP:rs4818952Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB076359 mRNA Translation: BAD01546.1
AL773602 Genomic DNA No translation available.
BC131611 mRNA Translation: AAI31612.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS42962.1

NCBI Reference Sequences

More...RefSeqi		NP_941965.2, NM_198692.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000334670; ENSP00000334197; ENSG00000243489

Database of genes from NCBI RefSeq genomes

More...GeneIDi		386678

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:386678

UCSC genome browser

More...UCSCi		uc002zfr.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB076359 mRNA Translation: BAD01546.1
AL773602 Genomic DNA No translation available.
BC131611 mRNA Translation: AAI31612.1
CCDSiCCDS42962.1
RefSeqiNP_941965.2, NM_198692.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi132129, 38 interactors
IntActiP60412, 38 interactors
STRINGi9606.ENSP00000334197

Genetic variation databases

BioMutaiKRTAP10-11
DMDMi296439312

Proteomic databases

MassIVEiP60412
PaxDbiP60412
PeptideAtlasiP60412
PRIDEiP60412
ProteomicsDBi57206

Genome annotation databases

EnsembliENST00000334670; ENSP00000334197; ENSG00000243489
GeneIDi386678
KEGGihsa:386678
UCSCiuc002zfr.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		386678

GeneCards: human genes, protein and diseases

More...GeneCardsi		KRTAP10-11
HGNCiHGNC:20528, KRTAP10-11
HPAiENSG00000243489, Tissue enriched (skin)
neXtProtiNX_P60412
OpenTargetsiENSG00000243489
PharmGKBiPA134873081
VEuPathDBiHostDB:ENSG00000243489.4

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4726, Eukaryota
GeneTreeiENSGT00940000165026
InParanoidiP60412
OMAiSECAGNC
OrthoDBi1622331at2759
PhylomeDBiP60412
TreeFamiTF351356

Enzyme and pathway databases

PathwayCommonsiP60412
ReactomeiR-HSA-6805567, Keratinization

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		386678, 11 hits in 841 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		386678
PharosiP60412, Tdark

Protein Ontology

More...PROi		PR:P60412
RNActiP60412, protein

Gene expression databases

BgeeiENSG00000243489, Expressed in quadriceps femoris and 40 other tissues
GenevisibleiP60412, HS

Family and domain databases

InterProiView protein in InterPro
IPR002494, KAP
PANTHERiPTHR23262, PTHR23262, 3 hits
PfamiView protein in Pfam
PF13885, Keratin_B2_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKR10B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P60412
Secondary accession number(s): A2RRF9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: May 18, 2010
Last modified: February 10, 2021
This is version 122 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. SIMILARITY comments
    Index of protein domains and families
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