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Entry version 127 (22 Apr 2020)
Sequence version 2 (17 Oct 2006)
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Protein

Keratin-associated protein 10-8

Gene

KRTAP10-8

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6805567 Keratinization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Keratin-associated protein 10-8
Alternative name(s):
High sulfur keratin-associated protein 10.8
Keratin-associated protein 10.8
Keratin-associated protein 18-8
Keratin-associated protein 18.8
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KRTAP10-8
Synonyms:KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:20525 KRTAP10-8

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P60410

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Keratin

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
386681

Open Targets

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OpenTargetsi
ENSG00000187766

The Pharmacogenetics and Pharmacogenomics Knowledge Base

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PharmGKBi
PA134968895

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P60410 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

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BioMutai
KRTAP10-8

Domain mapping of disease mutations (DMDM)

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DMDMi
116242612

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001852161 – 259Keratin-associated protein 10-8Add BLAST259

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P60410

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P60410

PeptideAtlas

More...
PeptideAtlasi
P60410

PRoteomics IDEntifications database

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PRIDEi
P60410

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
57204

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P60410

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P60410

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000187766 Expressed in skin of leg and 6 other tissues

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000187766 Tissue enriched (skin)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with hair keratins.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

P60410
With#Exp.IntAct
A0A384ME256EBI-10171774,EBI-10211777
itself6EBI-10171774,EBI-10171774
Q5BKY63EBI-10171774,EBI-10243533
Q5XG853EBI-10171774,EBI-10248413
Q6ZVW33EBI-10171774,EBI-10255586
Q9NWL93EBI-10171774,EBI-10315054
ACY3 [Q96HD9]3EBI-10171774,EBI-3916242
ADAM12 - isoform 4 [O43184-4]5EBI-10171774,EBI-12006944
ADAMTS1 [Q9UHI8]3EBI-10171774,EBI-2511802
ADAMTSL3 [P82987]6EBI-10171774,EBI-10221726
ADAMTSL4 - isoform 3 [Q6UY14-3]6EBI-10171774,EBI-10173507
AEBP2 - isoform 2 [Q6ZN18-2]3EBI-10171774,EBI-10255023
AEN [Q8WTP8]3EBI-10171774,EBI-8637627
AK3 [Q9UIJ7]3EBI-10171774,EBI-3916527
ALDH3B1 [P43353]6EBI-10171774,EBI-2558314
ALPI [P09923]3EBI-10171774,EBI-1052631
ALPP [P05187]3EBI-10171774,EBI-1211484
AMMECR1 [Q9Y4X0]3EBI-10171774,EBI-8583355
AMMECR1 - isoform 3 [Q9Y4X0-3]3EBI-10171774,EBI-12823597
ANKS1A [Q49AR9]5EBI-10171774,EBI-11954519
AP1M1 [Q9BXS5]3EBI-10171774,EBI-541426
APOL6 [B3KTP4]3EBI-10171774,EBI-10175904
APOL6 [Q9BWW8]3EBI-10171774,EBI-11574440
AQP1 [P29972]3EBI-10171774,EBI-745213
AREG [P15514]3EBI-10171774,EBI-953674
ARID5A [Q03989]3EBI-10171774,EBI-948603
ASPSCR1 [Q9BZE9]3EBI-10171774,EBI-1993677
ATG9A [Q7Z3C6]3EBI-10171774,EBI-727146
ATG9A - isoform 3 [Q7Z3C6-3]5EBI-10171774,EBI-12006308
ATP5F1D [P30049]3EBI-10171774,EBI-1049505
AVPI1 [Q5T686]3EBI-10171774,EBI-8640233
AXIN2 [Q9Y2T1]3EBI-10171774,EBI-4400025
BAHD1 [Q8TBE0]3EBI-10171774,EBI-742750
BCL6B [A8KA13]3EBI-10171774,EBI-10174813
BEX2 [Q9BXY8]6EBI-10171774,EBI-745073
BMP7 [A8K571]3EBI-10171774,EBI-10174327
BMP7 [P18075]3EBI-10171774,EBI-1035195
C10orf62 [Q5T681]3EBI-10171774,EBI-744052
C11orf87 [Q6NUJ2]6EBI-10171774,EBI-6660291
C17orf50 [Q8WW18]3EBI-10171774,EBI-12877892
C19orf25 [Q9UFG5]3EBI-10171774,EBI-741214
C19orf57 - isoform 2 [Q0VDD7-2]3EBI-10171774,EBI-12040255
C22orf39 [Q6P5X5]5EBI-10171774,EBI-7317823
C2orf68 [Q2NKX9]3EBI-10171774,EBI-11603468
C3 [P01024]3EBI-10171774,EBI-905851
CAMK1G [Q96NX5]3EBI-10171774,EBI-3920838
CARD10 [Q9BWT7]3EBI-10171774,EBI-3866279
CARHSP1 [Q9Y2V2]6EBI-10171774,EBI-718719
CATSPER1 [Q8NEC5]8EBI-10171774,EBI-744545
CCDC26 [Q8TAB7]3EBI-10171774,EBI-10271580
CCNJL [F6RF56]3EBI-10171774,EBI-10177725
CHIC2 [Q9UKJ5]6EBI-10171774,EBI-741528
CHRD [Q9H2X0]6EBI-10171774,EBI-947551
CHRNG [P07510]4EBI-10171774,EBI-9008836
CHRNG - isoform 2 [P07510-2]6EBI-10171774,EBI-11979451
CLK4 [Q9HAZ1]3EBI-10171774,EBI-633400
CNNM3 [Q8NE01]6EBI-10171774,EBI-741032
COL8A1 [P27658]8EBI-10171774,EBI-747133
COX17 [Q14061]3EBI-10171774,EBI-711311
CRCT1 [Q9UGL9]6EBI-10171774,EBI-713677
CREB5 - isoform 3 [Q02930-3]10EBI-10171774,EBI-10192698
CRH [P06850]3EBI-10171774,EBI-3870390
CRY2 [Q49AN0]3EBI-10171774,EBI-2212355
CSF1 [P09603]3EBI-10171774,EBI-2872294
CTRC [Q99895]3EBI-10171774,EBI-10295404
CYP2S1 [Q96SQ9]3EBI-10171774,EBI-8633740
CYSRT1 [A8MQ03]6EBI-10171774,EBI-3867333
DCX [O43602]3EBI-10171774,EBI-8646694
DDX43 [Q9NXZ2]3EBI-10171774,EBI-10316543
DDX55 [Q8NHQ9]3EBI-10171774,EBI-5459844
DDX6 [P26196]6EBI-10171774,EBI-351257
DERL2 [Q9GZP9]3EBI-10171774,EBI-7962814
DHRS1 [Q96LJ7]8EBI-10171774,EBI-746300
DHX57 [Q6P158]6EBI-10171774,EBI-1051531
DMRT3 [Q9NQL9]6EBI-10171774,EBI-9679045
DOCK2 [Q92608]6EBI-10171774,EBI-448771
ECE1 [P42892]3EBI-10171774,EBI-2859983
EFEMP2 [O95967]3EBI-10171774,EBI-743414
EIF4E2 [O60573]3EBI-10171774,EBI-398610
ENKD1 [Q9H0I2]3EBI-10171774,EBI-744099
EPDR1 [Q9UM22]3EBI-10171774,EBI-946972
FADS6 [Q8N9I5]3EBI-10171774,EBI-3943864
FAH [P16930]3EBI-10171774,EBI-4397076
FAM110A [Q9BQ89]3EBI-10171774,EBI-1752811
FAM161A [Q3B820]3EBI-10171774,EBI-719941
FAM221B [A6H8Z2]3EBI-10171774,EBI-12006844
FAM27E3 [Q08E93]3EBI-10171774,EBI-2602739
FAM71C [Q8NEG0]3EBI-10171774,EBI-752049
FAM74A6 [Q5TZK3]3EBI-10171774,EBI-10247271
FAM76B [Q5HYJ3]3EBI-10171774,EBI-751192
FAM76B - isoform 3 [Q5HYJ3-3]3EBI-10171774,EBI-11956087
FAM90A1 [Q86YD7]3EBI-10171774,EBI-6658203
FARS2 [O95363]3EBI-10171774,EBI-2513774
FBXO34 [Q9NWN3]3EBI-10171774,EBI-719816
FBXW5 [Q969U6]6EBI-10171774,EBI-741068
FEZF1 [A0PJY2]3EBI-10171774,EBI-11988727
FOXB1 [Q99853]3EBI-10171774,EBI-3916225
FRS3 [O43559]3EBI-10171774,EBI-725515
FTHL17 [Q9BXU8]3EBI-10171774,EBI-12156897
FZD10 [Q9ULW2]3EBI-10171774,EBI-8803802
GEM [P55040]3EBI-10171774,EBI-744104
GFOD1 [Q9NXC2]3EBI-10171774,EBI-8799578
GLP1R [P43220]3EBI-10171774,EBI-7466542
GLRX3 [O76003]8EBI-10171774,EBI-374781
GLYAT [Q6IB77]3EBI-10171774,EBI-715463
GNAI2 [P04899]3EBI-10171774,EBI-353997
GNE [Q9Y223]3EBI-10171774,EBI-4291090
GNE - isoform 2 [Q9Y223-2]5EBI-10171774,EBI-11975289
GOLGA8DP [Q0D2H9]3EBI-10171774,EBI-10181276
GPANK1 [O95872]3EBI-10171774,EBI-751540
GPHB5 [Q86YW7]3EBI-10171774,EBI-11659720
GRN [P28799]3EBI-10171774,EBI-747754
GUCD1 - isoform 2 [Q96NT3-2]5EBI-10171774,EBI-11978177
H2AFY [O75367]3EBI-10171774,EBI-2868511
HAPLN2 [Q9GZV7]3EBI-10171774,EBI-11956675
HCK - isoform 2 [P08631-2]3EBI-10171774,EBI-9834454
HEL-S-90n [V9HWJ5]3EBI-10171774,EBI-10330335
HHEX [Q03014]6EBI-10171774,EBI-747421
HOXA1 [P49639]9EBI-10171774,EBI-740785
HOXB5 [P09067]3EBI-10171774,EBI-3893317
HOXB9 [P17482]3EBI-10171774,EBI-745290
HOXC8 [P31273]5EBI-10171774,EBI-1752118
HPCAL1 [P37235]6EBI-10171774,EBI-749311
HS6ST1 [O60243]3EBI-10171774,EBI-12294537
HSD3B7 [Q9H2F3]8EBI-10171774,EBI-3918847
HSPA12B [Q96MM6]3EBI-10171774,EBI-10291310
HSPD1 [P10809]3EBI-10171774,EBI-352528
ICAM1 [P05362]3EBI-10171774,EBI-1035358
IGFBP6 [P24592]3EBI-10171774,EBI-947015
IGSF8 [Q969P0]6EBI-10171774,EBI-8293590
IL10 [P22301]3EBI-10171774,EBI-1031632
IL16 - isoform 2 [Q14005-2]3EBI-10171774,EBI-17178971
IL2RG [P31785]3EBI-10171774,EBI-80475
INO80B [Q9C086]3EBI-10171774,EBI-715611
INTS5 [Q6P9B9]3EBI-10171774,EBI-7600112
IP6K3 [Q96PC2]3EBI-10171774,EBI-10990676
ITGB2 [P05107]3EBI-10171774,EBI-300173
ITGB4 - isoform Beta-4A [P16144-2]3EBI-10171774,EBI-11051601
ITGB5 [L7RT22]3EBI-10171774,EBI-10178729
ITGB5 [P18084]3EBI-10171774,EBI-1223434
JOSD1 [Q15040]6EBI-10171774,EBI-2510602
JPH3 [Q8WXH2]3EBI-10171774,EBI-1055254
KLHL38 [Q2WGJ6]6EBI-10171774,EBI-6426443
KLK8 [O60259]3EBI-10171774,EBI-3915857
KPRP [Q5T749]3EBI-10171774,EBI-10981970
KRT20 [P35900]6EBI-10171774,EBI-742094
KRT83 [P78385]3EBI-10171774,EBI-10221390
KRTAP1-1 [Q07627]3EBI-10171774,EBI-11959885
KRTAP10-10 [P60014]3EBI-10171774,EBI-11955579
KRTAP10-11 [P60412]3EBI-10171774,EBI-10217483
KRTAP10-5 [P60370]3EBI-10171774,EBI-10172150
KRTAP10-7 [P60409]6EBI-10171774,EBI-10172290
KRTAP10-9 [P60411]6EBI-10171774,EBI-10172052
KRTAP11-1 [Q8IUC1]3EBI-10171774,EBI-1052037
KRTAP12-1 [P59990]6EBI-10171774,EBI-10210845
KRTAP12-2 [P59991]3EBI-10171774,EBI-10176379
KRTAP12-3 [P60328]3EBI-10171774,EBI-11953334
KRTAP15-1 [Q3LI76]3EBI-10171774,EBI-11992140
KRTAP17-1 [Q9BYP8]3EBI-10171774,EBI-11988175
KRTAP19-7 [Q3SYF9]3EBI-10171774,EBI-10241353
KRTAP3-1 [Q9BYR8]3EBI-10171774,EBI-9996449
KRTAP3-2 [Q9BYR7]3EBI-10171774,EBI-751260
KRTAP4-11 [Q9BYQ6]9EBI-10171774,EBI-10302392
KRTAP4-12 [Q9BQ66]6EBI-10171774,EBI-739863
KRTAP4-2 [Q9BYR5]10EBI-10171774,EBI-10172511
KRTAP4-4 [Q9BYR3]4EBI-10171774,EBI-11958132
KRTAP4-5 [Q9BYR2]3EBI-10171774,EBI-11993254
KRTAP4-7 [Q9BYR0]3EBI-10171774,EBI-10302547
KRTAP5-11 [Q6L8G4]3EBI-10171774,EBI-11993296
KRTAP5-2 [Q701N4]3EBI-10171774,EBI-11958178
KRTAP5-3 [Q6L8H2]3EBI-10171774,EBI-11974251
KRTAP5-4 [Q6L8H1]3EBI-10171774,EBI-11963072
KRTAP5-6 [Q6L8G9]8EBI-10171774,EBI-10250562
KRTAP5-9 [P26371]6EBI-10171774,EBI-3958099
KRTAP9-2 [Q9BYQ4]11EBI-10171774,EBI-1044640
KRTAP9-3 [Q9BYQ3]3EBI-10171774,EBI-1043191
KRTAP9-4 [Q9BYQ2]3EBI-10171774,EBI-10185730
KRTAP9-8 [Q9BYQ0]5EBI-10171774,EBI-11958364
LAGE3 [Q14657]3EBI-10171774,EBI-1052105
LASP1 - isoform 2 [Q14847-2]3EBI-10171774,EBI-9088686
LCE1A [Q5T7P2]6EBI-10171774,EBI-11962058
LCE1B [Q5T7P3]10EBI-10171774,EBI-10245913
LCE1C [Q5T751]3EBI-10171774,EBI-12224199
LCE1D [Q5T752]3EBI-10171774,EBI-11741311
LCE1E [Q5T753]3EBI-10171774,EBI-11955335
LCE1F [Q5T754]6EBI-10171774,EBI-11958008
LCE2A [Q5TA79]8EBI-10171774,EBI-10246607
LCE2B [O14633]6EBI-10171774,EBI-11478468
LCE2C [Q5TA81]3EBI-10171774,EBI-11973993
LCE2D [Q5TA82]8EBI-10171774,EBI-10246750
LCE3A [Q5TA76]5EBI-10171774,EBI-9394625
LCE3B [Q5TA77]3EBI-10171774,EBI-11974495
LCE3C [Q5T5A8]6EBI-10171774,EBI-10245291
LCE3D [Q9BYE3]5EBI-10171774,EBI-6658837
LCE3E [Q5T5B0]11EBI-10171774,EBI-10245456
LCE4A [Q5TA78]9EBI-10171774,EBI-10246358
LCE5A [Q5TCM9]5EBI-10171774,EBI-11955689
LELP1 [Q5T871]3EBI-10171774,EBI-18115868
LENG1 [Q96BZ8]3EBI-10171774,EBI-726510
LMF2 - isoform 2 [Q9BU23-2]3EBI-10171774,EBI-12132296
LNX1 [Q8TBB1]3EBI-10171774,EBI-739832
LOC200261 [Q17RD9]3EBI-10171774,EBI-10239007
LRCH4 [O75427]3EBI-10171774,EBI-718707
LRFN4 [Q6PJG9]3EBI-10171774,EBI-7910762
LUZP4 [Q9P127]3EBI-10171774,EBI-10198848
LYVE1 [Q9Y5Y7]3EBI-10171774,EBI-10329546
MAPKBP1 [O60336]8EBI-10171774,EBI-947402
MATN3 [O15232]3EBI-10171774,EBI-6262458
MEIS2 - isoform 4 [O14770-4]3EBI-10171774,EBI-8025850
MELTF - isoform 2 [P08582-2]3EBI-10171774,EBI-10195914
MEOX2 [P50222]3EBI-10171774,EBI-748397
MEOX2 [Q6FHY5]3EBI-10171774,EBI-16439278
MLLT6 [Q6P2C6]3EBI-10171774,EBI-5773143
MOBP [Q13875]3EBI-10171774,EBI-10230628
MOBP - isoform 3 [Q13875-3]3EBI-10171774,EBI-12013470
MTA1 [Q13330]3EBI-10171774,EBI-714236
MUL1 [Q969V5]3EBI-10171774,EBI-744120
MXI1 - isoform 3 [P50539-3]6EBI-10171774,EBI-10211940
MYPOP [Q86VE0]3EBI-10171774,EBI-2858213
NAB2 [Q15742]3EBI-10171774,EBI-8641936
NAXD [Q8IW45]6EBI-10171774,EBI-8650724
NECTIN2 - isoform Alpha [Q92692-2]3EBI-10171774,EBI-6979889
NECTIN3 [Q9NQS3]3EBI-10171774,EBI-2826725
NECTIN3 - isoform 2 [Q9NQS3-2]3EBI-10171774,EBI-12106440
NEK6 - isoform 4 [Q9HC98-4]3EBI-10171774,EBI-11750983
NKD1 [Q969G9]3EBI-10171774,EBI-1538217
NOTCH2NLA [Q7Z3S9]3EBI-10171774,EBI-945833
NOTCH2NLC [P0DPK4]3EBI-10171774,EBI-22310682
NPDC1 [Q9NQX5]3EBI-10171774,EBI-748927
NR1D2 [Q6NSM0]8EBI-10171774,EBI-10250949
NR4A3 [Q92570]3EBI-10171774,EBI-13644623
NTN4 [Q9HB63]3EBI-10171774,EBI-743459
NUFIP2 [Q7Z417]6EBI-10171774,EBI-1210753
OLIG3 [Q7RTU3]5EBI-10171774,EBI-10225049
OPCML [Q14982]3EBI-10171774,EBI-6447201
OTX1 [P32242]8EBI-10171774,EBI-740446
P2RX7 [Q99572]3EBI-10171774,EBI-1753251
P2RY6 [Q15077]3EBI-10171774,EBI-10235794
PAX5 [Q02548]3EBI-10171774,EBI-296331
PCED1A [Q9H1Q7]3EBI-10171774,EBI-748452
PCSK5 [Q92824]3EBI-10171774,EBI-751290
PCSK5 - isoform PC6A [Q92824-2]6EBI-10171774,EBI-11956269
PDE9A [O76083]3EBI-10171774,EBI-742764
PDE9A - isoform PDE9A2 [O76083-2]3EBI-10171774,EBI-11524542
PDIA4 [P13667]3EBI-10171774,EBI-1054653
PHLDA1 [A2BDE7]3EBI-10171774,EBI-14084211
PIGS [Q96S52]3EBI-10171774,EBI-2908273
PIN1 [Q13526]3EBI-10171774,EBI-714158
PKD2 [Q13563]3EBI-10171774,EBI-7813714
PLSCR4 [Q9NRQ2]3EBI-10171774,EBI-769257
POU1F1 [P28069]3EBI-10171774,EBI-8673859
POU4F2 [Q12837]3EBI-10171774,EBI-17236143
PRKAB2 [O43741]6EBI-10171774,EBI-1053424
PRPF31 [Q8WWY3]9EBI-10171774,EBI-1567797
PRR13 [Q9NZ81]6EBI-10171774,EBI-740924
PRR19 - isoform 2 [A6NJB7-2]3EBI-10171774,EBI-11998870
PTGER3 - isoform 12 [P43115-12]3EBI-10171774,EBI-10234038
PTK7 [Q13308]3EBI-10171774,EBI-2803245
PTPMT1 [Q8WUK0]6EBI-10171774,EBI-7199479
PTPRH [Q9HD43]3EBI-10171774,EBI-1267176
PVR [P15151]6EBI-10171774,EBI-3919694
QPRT [Q15274]3EBI-10171774,EBI-739851
R3HDM2 [Q9Y2K5]5EBI-10171774,EBI-948428
R3HDM2 - isoform 2 [Q9Y2K5-2]3EBI-10171774,EBI-10326419
RAB19 [A4D1S5]3EBI-10171774,EBI-4401710
RAB3A [P20336]3EBI-10171774,EBI-1045943
RALGDS - isoform 6 [Q12967-6]3EBI-10171774,EBI-12005546
RASD1 [Q9Y272]3EBI-10171774,EBI-740818
RECK [Q6P9E2]3EBI-10171774,EBI-10253121
RGL2 [O15211]3EBI-10171774,EBI-712355
RHBDL1 [O75783]3EBI-10171774,EBI-12104986
RHNO1 [Q9BSD3]3EBI-10171774,EBI-9658624
RNF38 [Q9H0F5]3EBI-10171774,EBI-2341200
RNF8 [O76064]3EBI-10171774,EBI-373337
RPS19BP1 [Q86WX3]3EBI-10171774,EBI-4479407
RPS28 [P62857]3EBI-10171774,EBI-353027
RTN4RL1 [Q86UN2]3EBI-10171774,EBI-10258951
SCARF1 [Q14162]3EBI-10171774,EBI-12056025
SCNM1 [Q9BWG6]6EBI-10171774,EBI-748391
SEMA3B - isoform 2 [Q13214-2]3EBI-10171774,EBI-11017428
SH3GLB2 [Q9NR46]3EBI-10171774,EBI-749607
SHFL [Q9NUL5]3EBI-10171774,EBI-10313866
SHFL - isoform 4 [Q9NUL5-4]3EBI-10171774,EBI-11955083
SLC13A5 [Q86YT5]3EBI-10171774,EBI-12002412
SLC22A23 [A1A5C7]3EBI-10171774,EBI-10171756
SLC23A1 [Q9UHI7]4EBI-10171774,EBI-1759386
SLC23A1 - isoform 3 [Q9UHI7-3]3EBI-10171774,EBI-11998660
SLC25A10 [Q9UBX3]3EBI-10171774,EBI-750394
SLC25A31 [Q9H0C2]3EBI-10171774,EBI-6149672
SLC25A42 [Q86VD7]3EBI-10171774,EBI-6598313
SLC6A20 [Q9NP91]6EBI-10171774,EBI-10311198
SLIT1 [O75093]3EBI-10171774,EBI-947791
SMARCE1 [Q969G3]3EBI-10171774,EBI-455078
SMCP [P49901]9EBI-10171774,EBI-750494
SMG9 [Q9H0W8]3EBI-10171774,EBI-2872322
SMOC1 [Q9H4F8]3EBI-10171774,EBI-2801103
SPACA9 [Q96E40]3EBI-10171774,EBI-722584
SPAG8 - isoform 2 [Q99932-2]3EBI-10171774,EBI-11959123
SPATA24 - isoform 2 [Q86W54-2]3EBI-10171774,EBI-12041693
SPATA3 [A0A024R4B0]3EBI-10171774,EBI-14123856
SPRY1 [O43609]6EBI-10171774,EBI-3866665
SPRY2 [O43597]3EBI-10171774,EBI-742487
STK16 [O75716]6EBI-10171774,EBI-749295
SUSD2 [Q9UGT4]3EBI-10171774,EBI-1054721
SUSD6 [Q92537]6EBI-10171774,EBI-2866213
SUV39H1 [O43463]3EBI-10171774,EBI-349968
TACSTD2 [P09758]3EBI-10171774,EBI-4324738
TAPBPL [Q9BX59]3EBI-10171774,EBI-12017416
TBC1D23 [Q9NUY8]3EBI-10171774,EBI-2853126
TCAF1 - isoform 2 [Q9Y4C2-2]3EBI-10171774,EBI-11974855
TCEA2 [Q15560]3EBI-10171774,EBI-710310
TCEANC - isoform 2 [Q8N8B7-2]3EBI-10171774,EBI-11955057
TFAP2D [Q7Z6R9]5EBI-10171774,EBI-11952651
TGFB1 [P01137]3EBI-10171774,EBI-779636
THAP10 [Q9P2Z0]3EBI-10171774,EBI-745404
THAP7 [Q9BT49]6EBI-10171774,EBI-741350
TIE1 [P35590]3EBI-10171774,EBI-2256865
TLE5 [Q08117]3EBI-10171774,EBI-717810
TLE5 - isoform 2 [Q08117-2]3EBI-10171774,EBI-11741437
TMEM140 [Q9NV12]3EBI-10171774,EBI-2844246
TMEM150A [Q86TG1]3EBI-10171774,EBI-2799342
TMEM8A [Q9HCN3]3EBI-10171774,EBI-10310808
TNIP3 [Q96KP6]3EBI-10171774,EBI-2509913
TNP2 [Q05952]3EBI-10171774,EBI-12039775
TNP2 [Q4VB56]3EBI-10171774,EBI-10241829
TNPO3 [Q9Y5L0]3EBI-10171774,EBI-1042571
TNS2 [Q63HR2]3EBI-10171774,EBI-949753
TRIM41 [Q8WV44]3EBI-10171774,EBI-725997
TRIM42 [Q8IWZ5]3EBI-10171774,EBI-5235829
TRPV6 [Q9Y260]3EBI-10171774,EBI-750052
TSPAN4 [O14817]3EBI-10171774,EBI-8652667
TTC23 - isoform 3 [Q5W5X9-3]3EBI-10171774,EBI-9090990
TXNDC5 [Q86UY0]3EBI-10171774,EBI-2825190
TYMSOS [Q8TAI1]3EBI-10171774,EBI-742060
TYRO3 [Q06418]3EBI-10171774,EBI-3951628
UBL5 [Q9BZL1]3EBI-10171774,EBI-607755
UTP23 [Q9BRU9]6EBI-10171774,EBI-5457544
UXT [Q9UBK9]6EBI-10171774,EBI-357355
VASN [Q6EMK4]3EBI-10171774,EBI-10249550
VENTX [O95231]3EBI-10171774,EBI-10191303
VEZF1 [Q14119]3EBI-10171774,EBI-11980193
VGLL3 - isoform 2 [A8MV65-2]3EBI-10171774,EBI-11957216
VPS11 [Q9H270]6EBI-10171774,EBI-373380
VWC2 [Q2TAL6]3EBI-10171774,EBI-11957238
VWC2L [B2RUY7]3EBI-10171774,EBI-11747707
WIF1 [Q9Y5W5]6EBI-10171774,EBI-3922719
WNT11 [O96014]3EBI-10171774,EBI-8058160
WT1 [P19544]3EBI-10171774,EBI-2320534
WT1-AS [Q06250]3EBI-10171774,EBI-10223946
YIPF3 [Q9GZM5]3EBI-10171774,EBI-743787
YY1 [P25490]3EBI-10171774,EBI-765538
ZBTB24 [O43167]6EBI-10171774,EBI-744471
ZBTB25 [P24278]3EBI-10171774,EBI-739899
ZDHHC1 [Q8WTX9]3EBI-10171774,EBI-2818796
ZFYVE21 [Q9BQ24]3EBI-10171774,EBI-2849569
ZIC1 [Q15915]3EBI-10171774,EBI-11963196
ZNF101 [Q8IZC7]3EBI-10171774,EBI-5278328
ZNF107 [Q9UII5]3EBI-10171774,EBI-7234993
ZNF121 [P58317]3EBI-10171774,EBI-1228269
ZNF124 [Q15973]6EBI-10171774,EBI-2555767
ZNF138 [P52744]3EBI-10171774,EBI-10746567
ZNF138 - isoform 2 [P52744-2]3EBI-10171774,EBI-10213071
ZNF165 [P49910]3EBI-10171774,EBI-741694
ZNF20 [P17024]6EBI-10171774,EBI-717634
ZNF23 [P17027]3EBI-10171774,EBI-5657766
ZNF250 - isoform 3 [P15622-3]3EBI-10171774,EBI-10177272
ZNF264 [O43296]3EBI-10171774,EBI-4395808
ZNF266 [Q14584]3EBI-10171774,EBI-7115319
ZNF319 [Q9P2F9]3EBI-10171774,EBI-11993110
ZNF32 [P17041]3EBI-10171774,EBI-1965483
ZNF330 [Q9Y3S2]3EBI-10171774,EBI-373456
ZNF408 [Q9H9D4]3EBI-10171774,EBI-347633
ZNF414 [Q96IQ9]3EBI-10171774,EBI-744257
ZNF417 [Q8TAU3]6EBI-10171774,EBI-740727
ZNF439 [Q8NDP4]6EBI-10171774,EBI-747580
ZNF440 [Q8IYI8]3EBI-10171774,EBI-726439
ZNF444 - isoform 2 [Q8N0Y2-2]3EBI-10171774,EBI-12010736
ZNF473 [Q8WTR7]6EBI-10171774,EBI-751409
ZNF490 [Q9ULM2]3EBI-10171774,EBI-1105370
ZNF491 [Q8N8L2]3EBI-10171774,EBI-12019860
ZNF497 [Q6ZNH5]3EBI-10171774,EBI-10486136
ZNF524 [Q96C55]3EBI-10171774,EBI-10283126
ZNF559 [Q9BR84]3EBI-10171774,EBI-746605
ZNF572 [Q7Z3I7]9EBI-10171774,EBI-10172590
ZNF575 [Q86XF7]3EBI-10171774,EBI-14069183
ZNF578 [Q3MI94]3EBI-10171774,EBI-10241108
ZNF578 [Q96N58]3EBI-10171774,EBI-11955189
ZNF580 [Q9UK33]3EBI-10171774,EBI-746277
ZNF581 [Q9P0T4]3EBI-10171774,EBI-745520
ZNF587 [Q96SQ5]6EBI-10171774,EBI-6427977
ZNF625 - isoform 2 [Q96I27-2]3EBI-10171774,EBI-12038525
ZNF648 [Q5T619]3EBI-10171774,EBI-11985915
ZNF669 [Q96BR6]3EBI-10171774,EBI-12006574
ZNF696 [Q9H7X3]3EBI-10171774,EBI-11090299
ZNF697 [Q8N508]3EBI-10171774,EBI-10265733
ZNF775 [Q96BV0]3EBI-10171774,EBI-7149881
ZNF786 [Q8N393]3EBI-10171774,EBI-10265203
ZNF79 [Q15937]3EBI-10171774,EBI-10237274
ZNF792 [Q3KQV3]3EBI-10171774,EBI-10240849
ZNF837 [Q96EG3]3EBI-10171774,EBI-11962574
ZSCAN12 [O43309]3EBI-10171774,EBI-1210440
ZSCAN21 [Q9Y5A6]6EBI-10171774,EBI-10281938

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
132132, 166 interactors

Protein interaction database and analysis system

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IntActi
P60410, 389 interactors

STRING: functional protein association networks

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STRINGi
9606.ENSP00000335565

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P60410 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati50 – 5415
Repeati60 – 6425
Repeati65 – 6935
Repeati98 – 10245
Repeati108 – 11255
Repeati118 – 12265
Repeati123 – 12775
Repeati133 – 13785
Repeati145 – 14995
Repeati155 – 159105
Repeati165 – 169115
Repeati170 – 174125
Repeati175 – 179135
Repeati187 – 191145
Repeati197 – 201155
Repeati202 – 206165
Repeati221 – 225175
Repeati228 – 232185
Repeati239 – 243195

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni26 – 24319 X 5 AA repeats of C-C-X(3)Add BLAST218

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the KRTAP type 10 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410JBGI Eukaryota
ENOG41118FU LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000163258

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_062832_0_0_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P60410

Identification of Orthologs from Complete Genome Data

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OMAi
CCVSMCS

Database of Orthologous Groups

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OrthoDBi
1583483at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
P60410

TreeFam database of animal gene trees

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TreeFami
TF351356

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002494 KAP
IPR007951 KRTAP_PMG

The PANTHER Classification System

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PANTHERi
PTHR23262 PTHR23262, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13885 Keratin_B2_2, 1 hit
PF05287 PMG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P60410-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADACCTRTY VIAASTMSVC SSDVGHVSRV SSPSTCTGSS WQVDNCQESC
60 70 80 90 100
CEPRSCASSC CTPSCCAPAP CLALVCAPVS CEPSPCQSGC TDSCTPSCCQ
110 120 130 140 150
QSSCQPACCT SSPCQQACCV PVCCKSNCCK PVCCVSICSG ASSPCCQQSS
160 170 180 190 200
CQSACCTFSP CQQACCVPIC CKPICCVPVC SGASSLCCQK SSCQPACCTT
210 220 230 240 250
SCCRPSSSVS LLCRPVCRPA CCVPVPSCCV PASSCQPSCC HPASCLSFLC

RPACSRLAC
Length:259
Mass (Da):26,299
Last modified:October 17, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i180307276CAB4607
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02823426H → R2 PublicationsCorresponds to variant dbSNP:rs411254Ensembl.1
Natural variantiVAR_03656064S → N in a colorectal cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_036561159S → F in a breast cancer sample; somatic mutation. 1 PublicationCorresponds to variant dbSNP:rs763238933Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AB076355 mRNA Translation: BAD01542.1
AL773602 Genomic DNA No translation available.
BC127016 mRNA Translation: AAI27017.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13713.1

NCBI Reference Sequences

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RefSeqi
NP_941968.2, NM_198695.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000334662; ENSP00000335565; ENSG00000187766

Database of genes from NCBI RefSeq genomes

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GeneIDi
386681

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:386681

UCSC genome browser

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UCSCi
uc002zfo.1 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB076355 mRNA Translation: BAD01542.1
AL773602 Genomic DNA No translation available.
BC127016 mRNA Translation: AAI27017.1
CCDSiCCDS13713.1
RefSeqiNP_941968.2, NM_198695.2

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi132132, 166 interactors
IntActiP60410, 389 interactors
STRINGi9606.ENSP00000335565

PTM databases

iPTMnetiP60410
PhosphoSitePlusiP60410

Polymorphism and mutation databases

BioMutaiKRTAP10-8
DMDMi116242612

Proteomic databases

MassIVEiP60410
PaxDbiP60410
PeptideAtlasiP60410
PRIDEiP60410
ProteomicsDBi57204

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
71343 1 antibodies

Genome annotation databases

EnsembliENST00000334662; ENSP00000335565; ENSG00000187766
GeneIDi386681
KEGGihsa:386681
UCSCiuc002zfo.1 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
386681
DisGeNETi386681

GeneCards: human genes, protein and diseases

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GeneCardsi
KRTAP10-8
HGNCiHGNC:20525 KRTAP10-8
HPAiENSG00000187766 Tissue enriched (skin)
neXtProtiNX_P60410
OpenTargetsiENSG00000187766
PharmGKBiPA134968895

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410JBGI Eukaryota
ENOG41118FU LUCA
GeneTreeiENSGT00940000163258
HOGENOMiCLU_062832_0_0_1
InParanoidiP60410
OMAiCCVSMCS
OrthoDBi1583483at2759
PhylomeDBiP60410
TreeFamiTF351356

Enzyme and pathway databases

ReactomeiR-HSA-6805567 Keratinization

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
386681
PharosiP60410 Tdark

Protein Ontology

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PROi
PR:P60410
RNActiP60410 protein

Gene expression databases

BgeeiENSG00000187766 Expressed in skin of leg and 6 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR002494 KAP
IPR007951 KRTAP_PMG
PANTHERiPTHR23262 PTHR23262, 1 hit
PfamiView protein in Pfam
PF13885 Keratin_B2_2, 1 hit
PF05287 PMG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKR108_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P60410
Secondary accession number(s): A0JNW4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: October 17, 2006
Last modified: April 22, 2020
This is version 127 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
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