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Entry version 120 (26 Feb 2020)
Sequence version 2 (25 Nov 2008)
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Protein

Keratin-associated protein 10-5

Gene

KRTAP10-5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6805567 Keratinization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Keratin-associated protein 10-5
Alternative name(s):
High sulfur keratin-associated protein 10.5
Keratin-associated protein 10.5
Keratin-associated protein 18-5
Keratin-associated protein 18.5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KRTAP10-5
Synonyms:KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:22969 KRTAP10-5

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P60370

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Keratin

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134950015

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P60370 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KRTAP10-5

Domain mapping of disease mutations (DMDM)

More...
DMDMi
215274018

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001852131 – 271Keratin-associated protein 10-5Add BLAST271

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P60370

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P60370

PeptideAtlas

More...
PeptideAtlasi
P60370

PRoteomics IDEntifications database

More...
PRIDEi
P60370

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
57199

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000241123 Expressed in skin of leg and 8 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with hair keratins.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-10172150,EBI-10172150
Q5BKY63EBI-10172150,EBI-10243533
Q5XG853EBI-10172150,EBI-10248413
Q9NWL93EBI-10172150,EBI-10315054
Q6UY14-35EBI-10172150,EBI-10173507
Q8WTP83EBI-10172150,EBI-8637627
P433533EBI-10172150,EBI-2558314
Q9Y2J4-43EBI-10172150,EBI-10187270
A8KA133EBI-10172150,EBI-10174813
A8K5713EBI-10172150,EBI-10174327
Q138955EBI-10172150,EBI-358049
Q6NUJ23EBI-10172150,EBI-6660291
Q9H2573EBI-10172150,EBI-751319
Q9H2X03EBI-10172150,EBI-947551
Q8NE013EBI-10172150,EBI-741032
Q02930-35EBI-10172150,EBI-10192698
Q6P1583EBI-10172150,EBI-1051531
P428923EBI-10172150,EBI-2859983
O605733EBI-10172150,EBI-398610
Q9H0I23EBI-10172150,EBI-744099
Q5TZK33EBI-10172150,EBI-10247271
Q5HYJ35EBI-10172150,EBI-751192
O953633EBI-10172150,EBI-2513774
P159763EBI-10172150,EBI-3909284
O760035EBI-10172150,EBI-374781
Q9Y2233EBI-10172150,EBI-4291090
Q0D2H93EBI-10172150,EBI-10181276
Q030143EBI-10172150,EBI-747421
P496395EBI-10172150,EBI-740785
P372353EBI-10172150,EBI-749311
P604093EBI-10172150,EBI-10172290
P599903EBI-10172150,EBI-10210845
P599913EBI-10172150,EBI-10176379
P0C7H83EBI-10172150,EBI-10196781
Q6PEX33EBI-10172150,EBI-3957672
Q9BYR75EBI-10172150,EBI-751260
Q9BQ663EBI-10172150,EBI-739863
Q9BYR57EBI-10172150,EBI-10172511
Q6L8G93EBI-10172150,EBI-10250562
P263719EBI-10172150,EBI-3958099
Q9BYQ45EBI-10172150,EBI-1044640
Q9BYQ25EBI-10172150,EBI-10185730
Q5T7P37EBI-10172150,EBI-10245913
Q5TA795EBI-10172150,EBI-10246607
Q5TA823EBI-10172150,EBI-10246750
Q5T5A86EBI-10172150,EBI-10245291
Q9BYE34EBI-10172150,EBI-6658837
Q5T5B05EBI-10172150,EBI-10245456
Q5TA783EBI-10172150,EBI-10246358
Q7Z4I7-53EBI-10172150,EBI-10257651
Q9P1273EBI-10172150,EBI-10198848
P502223EBI-10172150,EBI-748397
Q138753EBI-10172150,EBI-10230628
A1L3X43EBI-10172150,EBI-10172129
P50539-33EBI-10172150,EBI-10211940
P412273EBI-10172150,EBI-747693
Q926923EBI-10172150,EBI-718419
Q7Z3S95EBI-10172150,EBI-945833
Q9NQX53EBI-10172150,EBI-748927
P227363EBI-10172150,EBI-721550
Q7Z4177EBI-10172150,EBI-1210753
P322425EBI-10172150,EBI-740446
O437413EBI-10172150,EBI-1053424
Q9NZ813EBI-10172150,EBI-740924
Q9BWG63EBI-10172150,EBI-748391
Q9NUL53EBI-10172150,EBI-10313866
Q9UHI73EBI-10172150,EBI-1759386
Q9NP913EBI-10172150,EBI-10311198
P499013EBI-10172150,EBI-750494
Q96E403EBI-10172150,EBI-722584
O436093EBI-10172150,EBI-3866665
O435973EBI-10172150,EBI-742487
O757163EBI-10172150,EBI-749295
Q9P2Z03EBI-10172150,EBI-745404
Q4VB563EBI-10172150,EBI-10241829
Q63HR23EBI-10172150,EBI-949753
O753863EBI-10172150,EBI-5357290
Q86UY03EBI-10172150,EBI-2825190
Q8TAI13EBI-10172150,EBI-742060
Q9BRU93EBI-10172150,EBI-5457544
Q96HA83EBI-10172150,EBI-741158
Q062503EBI-10172150,EBI-10223946
O431673EBI-10172150,EBI-744471
P100743EBI-10172150,EBI-744864
Q9Y2603EBI-10172150,EBI-750052
Q9BQ243EBI-10172150,EBI-2849569
P170243EBI-10172150,EBI-717634
Q14C613EBI-10172150,EBI-2826570
Q145933EBI-10172150,EBI-3922471
Q9HBT8-23EBI-10172150,EBI-10310244
P170413EBI-10172150,EBI-1965483
A2RRD83EBI-10172150,EBI-10173019
Q86UD43EBI-10172150,EBI-7233259
Q8IZ263EBI-10172150,EBI-10264496
Q8TAU35EBI-10172150,EBI-740727
Q8N7K03EBI-10172150,EBI-10267553
Q8NDP43EBI-10172150,EBI-747580
Q9BR843EBI-10172150,EBI-746605
Q7Z3I73EBI-10172150,EBI-10172590
Q96SQ57EBI-10172150,EBI-6427977
Q9BS343EBI-10172150,EBI-745276
Q8IYX03EBI-10172150,EBI-745567
Q8N5083EBI-10172150,EBI-10265733
Q96C283EBI-10172150,EBI-748111
A8K8V03EBI-10172150,EBI-3925400
Q3KQV33EBI-10172150,EBI-10240849
Q9Y5A63EBI-10172150,EBI-10281938
Q166703EBI-10172150,EBI-3920053

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
P60370, 136 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000383223

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P60370 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati26 – 3015
Repeati51 – 5525
Repeati73 – 7735
Repeati78 – 8245
Repeati88 – 9255
Repeati93 – 9765
Repeati98 – 10275
Repeati110 – 11485
Repeati120 – 12495
Repeati130 – 134105
Repeati135 – 139115
Repeati140 – 144125
Repeati152 – 156135
Repeati162 – 166145
Repeati177 – 181155
Repeati187 – 191165
Repeati199 – 203175
Repeati209 – 213185
Repeati214 – 218195
Repeati233 – 237205
Repeati240 – 244215
Repeati251 – 255225

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni26 – 25522 X 5 AA repeats of C-C-X(3)Add BLAST230

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the KRTAP type 10 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JH3R Eukaryota
ENOG4111BSI LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_062832_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P60370

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P60370

TreeFam database of animal gene trees

More...
TreeFami
TF351356

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002494 KAP

The PANTHER Classification System

More...
PANTHERi
PTHR23262 PTHR23262, 4 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13885 Keratin_B2_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P60370-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAACTMSVCS SACSDSWRVD DCPESCCEPP CGTAPCLTLV CTPVSCVSSP
60 70 80 90 100
CCQAACEPSP CQSGCTSSCT PSCCQPACCA SSPCQQACCV PVCCKPVCCL
110 120 130 140 150
PTCSKDSSSC CQQSSCQPTC CASSSCQQSC CVPVCCKPVC CVPTCSEDSS
160 170 180 190 200
SCCQHSSCQP TCCTSSPCQQ SCYVPVCCKP VCFKPICCVP VCSGASTSCC
210 220 230 240 250
QQSSCQPACC TTSCCRPSSS VSLLCRPICR PACCVPISSC CAPASSYQAS
260 270
CCRPASCVSL LCRPACSRLA C
Length:271
Mass (Da):27,626
Last modified:November 25, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i20E32DB102D523ED
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0621134C → S. Corresponds to variant dbSNP:rs5017208Ensembl.1
Natural variantiVAR_01769620D → N1 PublicationCorresponds to variant dbSNP:rs2020221Ensembl.1
Natural variantiVAR_047505183F → C. Corresponds to variant dbSNP:rs380585Ensembl.1
Natural variantiVAR_017697235V → L1 PublicationCorresponds to variant dbSNP:rs464424Ensembl.1
Natural variantiVAR_047506247Y → C. Corresponds to variant dbSNP:rs7509970Ensembl.1
Natural variantiVAR_047507268R → P1 PublicationCorresponds to variant dbSNP:rs464391Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB076352 mRNA Translation: BAD01539.1
AL773602 Genomic DNA No translation available.
BC120949 mRNA Translation: AAI20950.1
BC120950 mRNA Translation: AAI20951.1
AJ566384 mRNA Translation: CAD97464.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS42958.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000400372; ENSP00000383223; ENSG00000241123

UCSC genome browser

More...
UCSCi
uc002zfl.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB076352 mRNA Translation: BAD01539.1
AL773602 Genomic DNA No translation available.
BC120949 mRNA Translation: AAI20950.1
BC120950 mRNA Translation: AAI20951.1
AJ566384 mRNA Translation: CAD97464.1
CCDSiCCDS42958.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiP60370, 136 interactors
STRINGi9606.ENSP00000383223

Polymorphism and mutation databases

BioMutaiKRTAP10-5
DMDMi215274018

Proteomic databases

MassIVEiP60370
PaxDbiP60370
PeptideAtlasiP60370
PRIDEiP60370
ProteomicsDBi57199

Genome annotation databases

EnsembliENST00000400372; ENSP00000383223; ENSG00000241123
UCSCiuc002zfl.2 human

Organism-specific databases

GeneCards: human genes, protein and diseases

More...
GeneCardsi
KRTAP10-5
HGNCiHGNC:22969 KRTAP10-5
neXtProtiNX_P60370
PharmGKBiPA134950015

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410JH3R Eukaryota
ENOG4111BSI LUCA
HOGENOMiCLU_062832_0_0_1
InParanoidiP60370
PhylomeDBiP60370
TreeFamiTF351356

Enzyme and pathway databases

ReactomeiR-HSA-6805567 Keratinization

Miscellaneous databases

PharosiP60370 Tdark

Protein Ontology

More...
PROi
PR:P60370
RNActiP60370 protein

Gene expression databases

BgeeiENSG00000241123 Expressed in skin of leg and 8 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR002494 KAP
PANTHERiPTHR23262 PTHR23262, 4 hits
PfamiView protein in Pfam
PF13885 Keratin_B2_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKR105_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P60370
Secondary accession number(s): Q0VAR7, Q0VAR8, Q70LJ3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: November 25, 2008
Last modified: February 26, 2020
This is version 120 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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