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Entry version 128 (11 Dec 2019)
Sequence version 1 (28 Nov 2003)
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Protein

Inactive ribonuclease-like protein 9

Gene

RNASE9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Does not exhibit any ribonuclease activity.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Inactive ribonuclease-like protein 9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RNASE9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000188655.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20673 RNASE9

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
614014 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P60153

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000188655

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134887351

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P60153 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RNASE9

Domain mapping of disease mutations (DMDM)

More...
DMDMi
38605140

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 261 PublicationAdd BLAST26
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003095127 – 205Inactive ribonuclease-like protein 9Add BLAST179

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi116 ↔ 168By similarity
Disulfide bondi123 ↔ 130By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi131N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi143N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P60153

PRoteomics IDEntifications database

More...
PRIDEi
P60153

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
57184 [P60153-1]
57185 [P60153-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P60153

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P60153

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

At the mRNA level, widely expressed (PubMed:18992174). At protein level, restricted to epididymis (PubMed:19137000). Expressed in spermatozoa (sperm head and neck), with higher levels on ejaculated and epididymal sperm than on testicular sperm (at protein level). Expressed in the epithelial cells of the epididymal tubule (at protein level). Not detected in muscle.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000188655 Expressed in 2 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P60153 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
133570, 1 interactor

Protein interaction database and analysis system

More...
IntActi
P60153, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000384683

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P60153 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P60153

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the pancreatic ribonuclease family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JD0F Eukaryota
ENOG4111BAS LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013952

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000236243

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P60153

Identification of Orthologs from Complete Genome Data

More...
OMAi
LITCRWQ

Database of Orthologous Groups

More...
OrthoDBi
1271649at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P60153

TreeFam database of animal gene trees

More...
TreeFami
TF338401

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.130.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029741 RNASE9
IPR001427 RNaseA
IPR036816 RNaseA-like_dom_sf
IPR023412 RNaseA_domain

The PANTHER Classification System

More...
PANTHERi
PTHR11437 PTHR11437, 1 hit
PTHR11437:SF14 PTHR11437:SF14, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00074 RnaseA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54076 SSF54076, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: P60153-1) [UniParc]FASTAAdd to basket
Also known as: alpha1, alpha2, alpha12, beta2, beta12

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMRTLITTHP LPLLLLPQQL LQLVQFQEVD TDFDFPEEDK KEEFEECLEK
60 70 80 90 100
FFSTGPARPP TKEKVKRRVL IEPGMPLNHI EYCNHEIMGK NVYYKHRWVA
110 120 130 140 150
EHYFLLMQYD ELQKICYNRF VPCKNGIRKC NRSKGLVEGV YCNLTEAFEI
160 170 180 190 200
PACKYESLYR KGYVLITCSW QNEMQKRIPH TINDLVEPPE HRSFLSEDGV

FVISP
Length:205
Mass (Da):24,307
Last modified:November 28, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEDE63F0727282BF6
GO
Isoform 2 (identifier: P60153-2) [UniParc]FASTAAdd to basket
Also known as: alpha23, alpha123

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MSAGKM

Show »
Length:210
Mass (Da):24,782
Checksum:iFCF929B3261222E6
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_052197148F → S3 PublicationsCorresponds to variant dbSNP:rs12590446Ensembl.1
Natural variantiVAR_034473204S → P3 PublicationsCorresponds to variant dbSNP:rs1243647Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0418561M → MSAGKM in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY665804 mRNA Translation: AAV87182.1
EU414264 mRNA Translation: ACA49544.1
AF382949 mRNA Translation: AAQ02792.1
AY907670 mRNA Translation: AAX86045.1
EF061296 mRNA Translation: ABP97451.1
EF061297 mRNA Translation: ABP97452.1
EF061298 mRNA Translation: ABP97453.1
EF061299 mRNA Translation: ABP97454.1
EF061300 mRNA Translation: ABP97455.1
EF061301 mRNA Translation: ABP97456.1
EF061302 mRNA Translation: ABP97457.1
EF061303 mRNA Translation: ABP97458.1
EF061304 mRNA Translation: ABP97459.1
AL163195 Genomic DNA No translation available.
BC130311 mRNA Translation: AAI30312.1
BC130313 mRNA Translation: AAI30314.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32036.1 [P60153-1]
CCDS53883.1 [P60153-2]
CCDS55904.1 [P60153-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001001673.2, NM_001001673.3 [P60153-1]
NP_001103826.1, NM_001110356.1 [P60153-1]
NP_001103827.1, NM_001110357.1 [P60153-1]
NP_001103828.1, NM_001110358.1 [P60153-2]
NP_001103829.1, NM_001110359.1 [P60153-2]
NP_001103830.1, NM_001110360.1 [P60153-2]
NP_001103831.1, NM_001110361.1 [P60153-2]
NP_001276039.1, NM_001289110.1 [P60153-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000338904; ENSP00000340162; ENSG00000188655 [P60153-1]
ENST00000404716; ENSP00000384683; ENSG00000188655 [P60153-2]
ENST00000429244; ENSP00000409504; ENSG00000188655 [P60153-1]
ENST00000553541; ENSP00000451285; ENSG00000188655 [P60153-1]
ENST00000553706; ENSP00000450570; ENSG00000188655 [P60153-2]
ENST00000554964; ENSP00000450599; ENSG00000188655 [P60153-1]
ENST00000555230; ENSP00000450800; ENSG00000188655 [P60153-1]
ENST00000556208; ENSP00000451160; ENSG00000188655 [P60153-2]
ENST00000557068; ENSP00000451565; ENSG00000188655 [P60153-1]
ENST00000557209; ENSP00000450987; ENSG00000188655 [P60153-2]
ENST00000611135; ENSP00000481786; ENSG00000188655 [P60153-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
390443

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:390443

UCSC genome browser

More...
UCSCi
uc001vxq.4 human [P60153-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY665804 mRNA Translation: AAV87182.1
EU414264 mRNA Translation: ACA49544.1
AF382949 mRNA Translation: AAQ02792.1
AY907670 mRNA Translation: AAX86045.1
EF061296 mRNA Translation: ABP97451.1
EF061297 mRNA Translation: ABP97452.1
EF061298 mRNA Translation: ABP97453.1
EF061299 mRNA Translation: ABP97454.1
EF061300 mRNA Translation: ABP97455.1
EF061301 mRNA Translation: ABP97456.1
EF061302 mRNA Translation: ABP97457.1
EF061303 mRNA Translation: ABP97458.1
EF061304 mRNA Translation: ABP97459.1
AL163195 Genomic DNA No translation available.
BC130311 mRNA Translation: AAI30312.1
BC130313 mRNA Translation: AAI30314.1
CCDSiCCDS32036.1 [P60153-1]
CCDS53883.1 [P60153-2]
CCDS55904.1 [P60153-2]
RefSeqiNP_001001673.2, NM_001001673.3 [P60153-1]
NP_001103826.1, NM_001110356.1 [P60153-1]
NP_001103827.1, NM_001110357.1 [P60153-1]
NP_001103828.1, NM_001110358.1 [P60153-2]
NP_001103829.1, NM_001110359.1 [P60153-2]
NP_001103830.1, NM_001110360.1 [P60153-2]
NP_001103831.1, NM_001110361.1 [P60153-2]
NP_001276039.1, NM_001289110.1 [P60153-1]

3D structure databases

SMRiP60153
ModBaseiSearch...

Protein-protein interaction databases

BioGridi133570, 1 interactor
IntActiP60153, 1 interactor
STRINGi9606.ENSP00000384683

PTM databases

iPTMnetiP60153
PhosphoSitePlusiP60153

Polymorphism and mutation databases

BioMutaiRNASE9
DMDMi38605140

Proteomic databases

PaxDbiP60153
PRIDEiP60153
ProteomicsDBi57184 [P60153-1]
57185 [P60153-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
390443

Genome annotation databases

EnsembliENST00000338904; ENSP00000340162; ENSG00000188655 [P60153-1]
ENST00000404716; ENSP00000384683; ENSG00000188655 [P60153-2]
ENST00000429244; ENSP00000409504; ENSG00000188655 [P60153-1]
ENST00000553541; ENSP00000451285; ENSG00000188655 [P60153-1]
ENST00000553706; ENSP00000450570; ENSG00000188655 [P60153-2]
ENST00000554964; ENSP00000450599; ENSG00000188655 [P60153-1]
ENST00000555230; ENSP00000450800; ENSG00000188655 [P60153-1]
ENST00000556208; ENSP00000451160; ENSG00000188655 [P60153-2]
ENST00000557068; ENSP00000451565; ENSG00000188655 [P60153-1]
ENST00000557209; ENSP00000450987; ENSG00000188655 [P60153-2]
ENST00000611135; ENSP00000481786; ENSG00000188655 [P60153-2]
GeneIDi390443
KEGGihsa:390443
UCSCiuc001vxq.4 human [P60153-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
390443
EuPathDBiHostDB:ENSG00000188655.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RNASE9
HGNCiHGNC:20673 RNASE9
MIMi614014 gene
neXtProtiNX_P60153
OpenTargetsiENSG00000188655
PharmGKBiPA134887351

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410JD0F Eukaryota
ENOG4111BAS LUCA
GeneTreeiENSGT00390000013952
HOGENOMiHOG000236243
InParanoidiP60153
OMAiLITCRWQ
OrthoDBi1271649at2759
PhylomeDBiP60153
TreeFamiTF338401

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
390443
PharosiP60153 Tdark

Protein Ontology

More...
PROi
PR:P60153
RNActiP60153 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000188655 Expressed in 2 organ(s), highest expression level in testis
ExpressionAtlasiP60153 baseline and differential

Family and domain databases

Gene3Di3.10.130.10, 1 hit
InterProiView protein in InterPro
IPR029741 RNASE9
IPR001427 RNaseA
IPR036816 RNaseA-like_dom_sf
IPR023412 RNaseA_domain
PANTHERiPTHR11437 PTHR11437, 1 hit
PTHR11437:SF14 PTHR11437:SF14, 1 hit
PfamiView protein in Pfam
PF00074 RnaseA, 1 hit
SUPFAMiSSF54076 SSF54076, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRNAS9_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P60153
Secondary accession number(s): A2RQR8
, A8QJS1, Q5GAN7, Q6KG53
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: November 28, 2003
Last modified: December 11, 2019
This is version 128 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
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