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Protein

Actin

Gene

ACT1

Organism
Saccharomyces bayanus (Yeast) (Saccharomyces uvarum x Saccharomyces eubayanus)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

GO - Molecular functioni

Keywordsi

LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Actin
Gene namesi
Name:ACT1
OrganismiSaccharomyces bayanus (Yeast) (Saccharomyces uvarum x Saccharomyces eubayanus)
Taxonomic identifieri4931 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000890011 – 375ActinAdd BLAST375

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiP60011

Structurei

Secondary structure

1375
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi8 – 12Combined sources5
Beta strandi14 – 21Combined sources8
Beta strandi28 – 32Combined sources5
Helixi56 – 60Combined sources5
Beta strandi70 – 72Combined sources3
Helixi79 – 90Combined sources12
Turni91 – 94Combined sources4
Helixi98 – 100Combined sources3
Beta strandi103 – 107Combined sources5
Helixi113 – 125Combined sources13
Beta strandi132 – 136Combined sources5
Helixi137 – 144Combined sources8
Beta strandi148 – 155Combined sources8
Beta strandi160 – 166Combined sources7
Beta strandi176 – 179Combined sources4
Helixi182 – 194Combined sources13
Helixi206 – 215Combined sources10
Helixi223 – 231Combined sources9
Beta strandi238 – 241Combined sources4
Beta strandi247 – 250Combined sources4
Helixi253 – 256Combined sources4
Helixi258 – 261Combined sources4
Helixi264 – 267Combined sources4
Helixi274 – 282Combined sources9
Turni287 – 289Combined sources3
Helixi290 – 294Combined sources5
Beta strandi297 – 301Combined sources5
Helixi302 – 304Combined sources3
Helixi309 – 320Combined sources12
Helixi335 – 337Combined sources3
Helixi338 – 348Combined sources11
Helixi352 – 354Combined sources3
Helixi359 – 365Combined sources7
Helixi366 – 369Combined sources4
Helixi370 – 373Combined sources4

3D structure databases

ProteinModelPortaliP60011
SMRiP60011
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.Curated

Family and domain databases

InterProiView protein in InterPro
IPR004000 Actin
IPR020902 Actin/actin-like_CS
IPR004001 Actin_CS
PANTHERiPTHR11937 PTHR11937, 1 hit
PfamiView protein in Pfam
PF00022 Actin, 1 hit
PRINTSiPR00190 ACTIN
SMARTiView protein in SMART
SM00268 ACTIN, 1 hit
PROSITEiView protein in PROSITE
PS00406 ACTINS_1, 1 hit
PS00432 ACTINS_2, 1 hit
PS01132 ACTINS_ACT_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

P60011-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSEVAALVI DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGIMVGMGQK
60 70 80 90 100
DSYVGDEAQS KRGILTLRYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE
110 120 130 140 150
HPVLLTEAPM NPKSNREKMT QIMFETFNVP AFYVSIQAVL SLYSSGRTTG
160 170 180 190 200
IVLDSGDGVT HVVPIYAGFS LPHAILRIDL AGRDLTDYLM KILSERGYSF
210 220 230 240 250
STTAEREIVR DIKEKLCYVA LDFEQEMQTA AQSSSIEKSY ELPDGQVITI
260 270 280 290 300
GNERFRAPEA LFHPSVLGLE SAGIDQTTYN SIMKCDVDVR KELYGNIVMS
310 320 330 340 350
GGTTMFPGIA ERMQKEITAL APSSMKVKII APPERKYSVW IGGSILASLT
360 370
TFQQMWISKQ EYDESGPSIV HHKCF
Length:375
Mass (Da):41,690
Last modified:July 21, 1986 - v1
Checksum:i87AC19B0B0BC9E71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12534 Genomic DNA Translation: BAA02097.1

Similar proteinsi

Entry informationi

Entry nameiACT_SACBA
AccessioniPrimary (citable) accession number: P60011
Secondary accession number(s): P02579
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: November 30, 2016
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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