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Protein

Major intrinsically disordered Notch2-binding receptor 1-like

Gene

KIAA1024L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Major intrinsically disordered Notch2-binding receptor 1-like
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000186367.6
HGNCiHGNC:33914 KIAA1024L
neXtProtiNX_P59773

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei169 – 189HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000186367

Polymorphism and mutation databases

DMDMi519668667

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001571351 – 190Major intrinsically disordered Notch2-binding receptor 1-likeAdd BLAST190

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei79PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP59773
PRIDEiP59773
ProteomicsDBi57157

PTM databases

iPTMnetiP59773
PhosphoSitePlusiP59773

Expressioni

Gene expression databases

BgeeiENSG00000186367 Expressed in 11 organ(s), highest expression level in skeletal muscle tissue
CleanExiHS_KIAA1024L

Organism-specific databases

HPAiHPA013760

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000454268

Family & Domainsi

Sequence similaritiesi

Belongs to the MINAR family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IY4A Eukaryota
ENOG4111YKQ LUCA
GeneTreeiENSGT00530000063851
InParanoidiP59773
OMAiKYCRIGL
OrthoDBiEOG091G014I

Family and domain databases

InterProiView protein in InterPro
IPR039706 MINAR1-like
IPR009626 MINAR1-like_C
PANTHERiPTHR31530 PTHR31530, 1 hit
PfamiView protein in Pfam
PF06789 UPF0258, 1 hit

Sequencei

Sequence statusi: Complete.

P59773-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLSVLPNNN HPDKFLQLDV KSLTRSSALL QASLVRFPGG NYPAAQHWQN
60 70 80 90 100
LVYSQREKKN IAAQRIRGSS ADSLVTADSP PPSMSSVMKN NPLYGDLSLE
110 120 130 140 150
EAMEERKKNP SWTIEEYDKH SLHTNLSGHL KENPNDLRFW LGDMYTPGFD
160 170 180 190
TLLKKEEKQE KHSKFCRMGL ILLVVISILV TIVTIITFFT
Length:190
Mass (Da):21,573
Last modified:June 26, 2013 - v2
Checksum:i3BC483841BB66CA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008591 Genomic DNA No translation available.
CH471062 Genomic DNA Translation: EAW62380.1
CCDSiCCDS58966.1
RefSeqiNP_001244237.1, NM_001257308.1
UniGeneiHs.582534

Genome annotation databases

EnsembliENST00000564719; ENSP00000454268; ENSG00000186367
GeneIDi100127206
KEGGihsa:100127206
UCSCiuc031skx.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008591 Genomic DNA No translation available.
CH471062 Genomic DNA Translation: EAW62380.1
CCDSiCCDS58966.1
RefSeqiNP_001244237.1, NM_001257308.1
UniGeneiHs.582534

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000454268

PTM databases

iPTMnetiP59773
PhosphoSitePlusiP59773

Polymorphism and mutation databases

DMDMi519668667

Proteomic databases

PaxDbiP59773
PRIDEiP59773
ProteomicsDBi57157

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000564719; ENSP00000454268; ENSG00000186367
GeneIDi100127206
KEGGihsa:100127206
UCSCiuc031skx.2 human

Organism-specific databases

CTDi100127206
EuPathDBiHostDB:ENSG00000186367.6
GeneCardsiKIAA1024L
HGNCiHGNC:33914 KIAA1024L
HPAiHPA013760
neXtProtiNX_P59773
OpenTargetsiENSG00000186367
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IY4A Eukaryota
ENOG4111YKQ LUCA
GeneTreeiENSGT00530000063851
InParanoidiP59773
OMAiKYCRIGL
OrthoDBiEOG091G014I

Miscellaneous databases

PROiPR:P59773

Gene expression databases

BgeeiENSG00000186367 Expressed in 11 organ(s), highest expression level in skeletal muscle tissue
CleanExiHS_KIAA1024L

Family and domain databases

InterProiView protein in InterPro
IPR039706 MINAR1-like
IPR009626 MINAR1-like_C
PANTHERiPTHR31530 PTHR31530, 1 hit
PfamiView protein in Pfam
PF06789 UPF0258, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMNARL_HUMAN
AccessioniPrimary (citable) accession number: P59773
Secondary accession number(s): H3BM78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: June 26, 2013
Last modified: November 7, 2018
This is version 83 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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