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Entry version 123 (12 Aug 2020)
Sequence version 2 (27 Jul 2011)
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Protein

Ras and Rab interactor 3

Gene

Rin3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGTPase activation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-8876198, RAB GEFs exchange GTP for GDP on RABs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ras and Rab interactor 3
Alternative name(s):
Ras interaction/interference protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rin3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2385708, Rin3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Endosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001913231 – 980Ras and Rab interactor 3Add BLAST980

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P59729

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P59729

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P59729

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P59729

PRoteomics IDEntifications database

More...
PRIDEi
P59729

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P59729

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P59729

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000044456, Expressed in granulocyte and 188 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P59729, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P59729, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CD2AP, RAB5B, RAB31 and BIN1.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
229966, 5 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000060771

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P59729, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini63 – 158SH2Add BLAST96
Domaini700 – 843VPS9PROSITE-ProRule annotationAdd BLAST144
Domaini865 – 962Ras-associatingPROSITE-ProRule annotationAdd BLAST98

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni584 – 729Interaction with RAB5BBy similarityAdd BLAST146

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi242 – 380Pro-richAdd BLAST139
Compositional biasi719 – 722Poly-Thr4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

SH2 domain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2320, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158622

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P59729

KEGG Orthology (KO)

More...
KOi
K23687

Identification of Orthologs from Complete Genome Data

More...
OMAi
QEIRMMM

Database of Orthologous Groups

More...
OrthoDBi
251004at2759

TreeFam database of animal gene trees

More...
TreeFami
TF331067

Family and domain databases

Conserved Domains Database

More...
CDDi
cd10395, SH2_RIN3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1050.80, 1 hit
3.30.505.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000159, RA_dom
IPR035869, RIN3_SH2
IPR036860, SH2_dom_sf
IPR003123, VPS9
IPR037191, VPS9_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02204, VPS9, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00314, RA, 1 hit
SM00167, VPS9, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109993, SSF109993, 1 hit
SSF55550, SSF55550, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50200, RA, 1 hit
PS51205, VPS9, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P59729-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRAEAPSSA HPAGPIPDAG KGEGEEDEEK DGTRLGLSTT PRNCIPRRGI
60 70 80 90 100
SVLEKLVKTC PVWLQLGLGQ AEAAKILQQE MAGMFLVCRD NNLKQLVLCV
110 120 130 140 150
HFPSLKGSSA EVLEYPIKEE KAILYLEGSV LVFEDIFRLI AFYCVSRDLL
160 170 180 190 200
PFTLRLPQAI LEASSFLELE TISNLGLGFW DSSLNSRGSA EPLRSPAPGT
210 220 230 240 250
PASSSLRPTT HYANCSCEIE LSVGNDRLWF VNPIFIEDCI LPADPPPLPT
260 270 280 290 300
GSYPPRPTPA TPDATSPTSK GSPRRPPPPP PLPTVPPTGP ARPLAPPVPP
310 320 330 340 350
AGPLPNSPLT PTSHLAPHAP GPPGHSNQPP MTACESLPRP AVGLGPFGEE
360 370 380 390 400
EMKPGTTPNP LHQAPPPPLP LKKALPAAPP RRRISERVSL ESQNVGTSTD
410 420 430 440 450
RDHSGISRTA SLNLPPQSTV SSLGDRPPRT TEQSQDTEAK ASHADSIPVP
460 470 480 490 500
PGKAKQPPVP PPRKKRVSRQ LASTLLSPLE SPIQEASSEK QATGASWEGL
510 520 530 540 550
SPVRQAGMQH LQVQSSSCPQ SSPEFKGSQA SLSDSLGVPA SAADQDSYST
560 570 580 590 600
SSAEEELEFS SPNVKKKPSM ILDKARHRLS FVSFASVFHA FLSSDRKLYK
610 620 630 640 650
KVVELAQDKS SYFGSLVQDY KVYSLEMMAR QTSSTEMLQE IRTMMTQLKS
660 670 680 690 700
YLLQSTELKA LVEPTLHSEE ELEAIVESAL YKCVLKPLKE AINSSLLEIH
710 720 730 740 750
SRDGSLQQLK ENQLVVLATT TTDLGVTTSV PEVAVMEKIL QKLTSMHKAY
760 770 780 790 800
SPGKKISILL KTCKLIYDSM ALGNPGKPYG ADDFLPVLMY VLARSNLTEM
810 820 830 840 850
LLNVEYMMEL MDPALQLGEG SYYLTTTYGA LEHIKNYDKI TVTRQLSVEV
860 870 880 890 900
QDSIHRWERR RTLNKARASR SSVQDFICVS YLKPEQQSRT LASRADTAAQ
910 920 930 940 950
ALCAQCAEKF EVSQPQDYRL FVLVDGRCFQ LADEALPHRI KGYLLRSEPK
960 970 980
RDFHFVYRPQ DSGKDASSQP CIVVREPNFL
Length:980
Mass (Da):107,220
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF803A8CFEE17A7B8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3U332Q3U332_MOUSE
Ras and Rab interactor 3
Rin3
900Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3Z076D3Z076_MOUSE
Ras and Rab interactor 3
Rin3
127Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q3UZ87Q3UZ87_MOUSE
Ras and Rab interactor 3
Rin3
198Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti288T → I in BAC27757 (PubMed:16141072).Curated1
Sequence conflicti332T → K in BAC27757 (PubMed:16141072).Curated1
Sequence conflicti560S → T in BAC27757 (PubMed:16141072).Curated1
Sequence conflicti563 – 565NVK → DVE in BAC27757 (PubMed:16141072).Curated3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK032205 mRNA Translation: BAC27757.1
BC137907 mRNA Translation: AAI37908.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS26118.1

NCBI Reference Sequences

More...
RefSeqi
NP_808288.2, NM_177620.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000056950; ENSMUSP00000060771; ENSMUSG00000044456

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
217835

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:217835

UCSC genome browser

More...
UCSCi
uc007ouc.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK032205 mRNA Translation: BAC27757.1
BC137907 mRNA Translation: AAI37908.1
CCDSiCCDS26118.1
RefSeqiNP_808288.2, NM_177620.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi229966, 5 interactors
STRINGi10090.ENSMUSP00000060771

PTM databases

iPTMnetiP59729
PhosphoSitePlusiP59729

Proteomic databases

EPDiP59729
jPOSTiP59729
MaxQBiP59729
PaxDbiP59729
PRIDEiP59729

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
26773, 73 antibodies

Genome annotation databases

EnsembliENSMUST00000056950; ENSMUSP00000060771; ENSMUSG00000044456
GeneIDi217835
KEGGimmu:217835
UCSCiuc007ouc.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79890
MGIiMGI:2385708, Rin3

Phylogenomic databases

eggNOGiKOG2320, Eukaryota
GeneTreeiENSGT00940000158622
InParanoidiP59729
KOiK23687
OMAiQEIRMMM
OrthoDBi251004at2759
TreeFamiTF331067

Enzyme and pathway databases

ReactomeiR-MMU-8876198, RAB GEFs exchange GTP for GDP on RABs

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
217835, 1 hit in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Rin3, mouse

Protein Ontology

More...
PROi
PR:P59729
RNActiP59729, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000044456, Expressed in granulocyte and 188 other tissues
ExpressionAtlasiP59729, baseline and differential
GenevisibleiP59729, MM

Family and domain databases

CDDicd10395, SH2_RIN3, 1 hit
Gene3Di1.20.1050.80, 1 hit
3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR000159, RA_dom
IPR035869, RIN3_SH2
IPR036860, SH2_dom_sf
IPR003123, VPS9
IPR037191, VPS9_dom_sf
PfamiView protein in Pfam
PF02204, VPS9, 1 hit
SMARTiView protein in SMART
SM00314, RA, 1 hit
SM00167, VPS9, 1 hit
SUPFAMiSSF109993, SSF109993, 1 hit
SSF55550, SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50200, RA, 1 hit
PS51205, VPS9, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRIN3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P59729
Secondary accession number(s): B2RQF8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2003
Last sequence update: July 27, 2011
Last modified: August 12, 2020
This is version 123 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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