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UniProtKB - P59644 (PI5PA_MOUSE)

Entry version 142 (07 Apr 2021)
Sequence version 2 (27 Jul 2011)
Previous versions | rss
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Protein

Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

Gene

Inpp5j

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-1660499, Synthesis of PIPs at the plasma membrane
R-MMU-1855183, Synthesis of IP2, IP, and Ins in the cytosol
R-MMU-1855204, Synthesis of IP3 and IP4 in the cytosol

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC:3.1.3.56)
Alternative name(s):
Inositol polyphosphate 5-phosphatase J
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Inpp5j
Synonyms:Pib5pa
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2158663, Inpp5j

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002097391 – 1003Phosphatidylinositol 4,5-bisphosphate 5-phosphatase AAdd BLAST1003

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei56Asymmetric dimethylarginine; alternateCombined sources1
Modified residuei56Omega-N-methylarginine; alternateCombined sources1
Modified residuei65Omega-N-methylarginineCombined sources1
Modified residuei76Asymmetric dimethylarginineCombined sources1
Modified residuei83Asymmetric dimethylarginine; alternateCombined sources1
Modified residuei83Omega-N-methylarginine; alternateCombined sources1
Modified residuei171PhosphoserineBy similarity1
Modified residuei292PhosphoserineCombined sources1
Modified residuei325PhosphoserineCombined sources1
Modified residuei900PhosphoserineBy similarity1
Modified residuei987PhosphoserineBy similarity1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		P59644

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P59644

PeptideAtlas

More...PeptideAtlasi		P59644

PRoteomics IDEntifications database

More...PRIDEi		P59644

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		289419

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P59644

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P59644

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000034570, Expressed in olfactory bulb and 267 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P59644, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P59644, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		228465, 2 interactors

Protein interaction database and analysis system

More...IntActi		P59644, 1 interactor

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000046625

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P59644, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P59644

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni422 – 725CatalyticSequence analysisAdd BLAST304
Regioni726 – 837Required for ruffle localizationAdd BLAST112

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi6 – 11RSXSXX motif 16
Motifi346 – 351SH3-bindingSequence analysis6
Motifi351 – 356RSXSXX motif 26
Motifi871 – 876RSXSXX motif 36
Motifi882 – 887RSXSXX motif 46
Motifi908 – 913RSXSXX motif 56

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi50 – 374Pro-richAdd BLAST325
Compositional biasi837 – 934Ser-richAdd BLAST98

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.Curated

Keywords - Domaini

Repeat, SH3-binding

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0565, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000156855

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_011711_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P59644

Database of Orthologous Groups

More...OrthoDBi		772410at2759

TreeFam database of animal gene trees

More...TreeFami		TF317034

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.60.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036691, Endo/exonu/phosph_ase_sf
IPR005135, Endo/exonuclease/phosphatase
IPR000300, IPPc
IPR041611, SKICH

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03372, Exo_endo_phos, 1 hit
PF17751, SKICH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00128, IPPc, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF56219, SSF56219, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

P59644-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGQTRSGSA RPGTRTGLGP LPGTHGVLQA EIPSKKVNSS FQLPAKNSGP 
        60         70         80         90        100
ASSEPRLTLA PVGPRAAVSP PSERPRLVLS SPRPVLAPLS IAGEQKRPPP 
       110        120        130        140        150
PHSSNRAAKS VGQLVVSAAA ASKPPPVASV SILAPKSLGQ LVISASAMPR 
       160        170        180        190        200
PSPAPLGSVL TPTSRDQKQL SPTSVGPKPA LATSGLSLAL ASQEQPPQSP 
       210        220        230        240        250
SSPSPVPSPV LSPSQEGHLA AASVTSTPAS ERQLPARQKD TAVPRPTPPA 
       260        270        280        290        300
DKCLYTPERA AGPATSPPRA QAFSDPRLSP SFRARPEAPR HSPEDPVLPP 
       310        320        330        340        350
PPQTLPLDVS PGLPESGTRS PGLLSPTFRP GIPSSQTVPP PLPKPPRSPS 
       360        370        380        390        400
RSPSRSPNRS PCLPPAPEVA LPKPVTQAAG SGRCPSPNLQ AQESPAAATT 
       410        420        430        440        450
TTSPTSSWSA QPTCKSDPGF RITVVTWNVG TAMPPDDVTS LLHLGSGHDN 
       460        470        480        490        500
DGADMIAIGL QEVNSMINKR LKDALFTDQW SELFMDALGP FNFVLVSTVR 
       510        520        530        540        550
MQGVILLLFA KYYHLPFLRD VQTDCTRTGL GGYWGNKGGV SVRLAAFGHM 
       560        570        580        590        600
LCFLNCHLPA HMDKAEQRKD NFQTILSLQQ FQGPGAHGIL DHDLVFWFGD 
       610        620        630        640        650
LNFRIESYDL HFVKFAIDSN QLHQLWEKDQ LNMAKNTWPI LKGFQEGPLN 
       660        670        680        690        700
FAPTFKFDVG TNKYDTSAKK RKPAWTDRIL WKVKAPSGGP SPSGRESHRL 
       710        720        730        740        750
QVTQHSYRSH MEYTVSDHKP VAAQFILQFA FRDDVPLVRL EVADEWARPE 
       760        770        780        790        800
QAVVRYRVET VFARSSWDWI GLYRVGFRHC KDYVAYVWAK HEEVDGNIYQ 
       810        820        830        840        850
VTFSEESLPK GHGDFILGYY SHHHSILIGV TEPFQISLPT SESASSSTDS 
       860        870        880        890        900
SGTSSEGEDD STLELLAPKS RSPSPGKSKR HRSRSPGLAR FPSLALHPSS 
       910        920        930        940        950
RERRGGSRSP SPQSRQLPRV APDRGHSSSS RGSSEEGPSG LPGPWAFPPS 
       960        970        980        990       1000
VPRSLGLLPA LRLETVDPGG GGSWGADQEA PDPNSLSPSP QGRLGLEEGG 

LGP
Length:1,003
Mass (Da):107,544
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3D2E1F6B3D060B4B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
V9GXL7V9GXL7_MOUSE
Inositol-polyphosphate 5-phosphatas...
Inpp5j
548Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A075B6D7A0A075B6D7_MOUSE
Inositol-polyphosphate 5-phosphatas...
Inpp5j
899Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3Z3Q0D3Z3Q0_MOUSE
Phosphatidylinositol 4,5-bisphospha...
Inpp5j
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3Z3P9D3Z3P9_MOUSE
Phosphatidylinositol 4,5-bisphospha...
Inpp5j
97Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GX61V9GX61_MOUSE
Phosphatidylinositol 4,5-bisphospha...
Inpp5j
41Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti343P → R in BAC28654 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK034272 mRNA Translation: BAC28654.1
AK170114 mRNA Translation: BAE41572.1
BC131634 mRNA Translation: AAI31635.1
BC131635 mRNA Translation: AAI31636.1
CH466574 Genomic DNA Translation: EDL40427.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS24364.1

NCBI Reference Sequences

More...RefSeqi		NP_766027.2, NM_172439.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000044507; ENSMUSP00000046625; ENSMUSG00000034570

Database of genes from NCBI RefSeq genomes

More...GeneIDi		170835

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:170835

UCSC genome browser

More...UCSCi		uc007hta.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK034272 mRNA Translation: BAC28654.1
AK170114 mRNA Translation: BAE41572.1
BC131634 mRNA Translation: AAI31635.1
BC131635 mRNA Translation: AAI31636.1
CH466574 Genomic DNA Translation: EDL40427.1
CCDSiCCDS24364.1
RefSeqiNP_766027.2, NM_172439.3

3D structure databases

SMRiP59644
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi228465, 2 interactors
IntActiP59644, 1 interactor
STRINGi10090.ENSMUSP00000046625

PTM databases

iPTMnetiP59644
PhosphoSitePlusiP59644

Proteomic databases

MaxQBiP59644
PaxDbiP59644
PeptideAtlasiP59644
PRIDEiP59644
ProteomicsDBi289419

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		5745, 201 antibodies

Genome annotation databases

EnsembliENSMUST00000044507; ENSMUSP00000046625; ENSMUSG00000034570
GeneIDi170835
KEGGimmu:170835
UCSCiuc007hta.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		27124
MGIiMGI:2158663, Inpp5j

Phylogenomic databases

eggNOGiKOG0565, Eukaryota
GeneTreeiENSGT00940000156855
HOGENOMiCLU_011711_3_0_1
InParanoidiP59644
OrthoDBi772410at2759
TreeFamiTF317034

Enzyme and pathway databases

ReactomeiR-MMU-1660499, Synthesis of PIPs at the plasma membrane
R-MMU-1855183, Synthesis of IP2, IP, and Ins in the cytosol
R-MMU-1855204, Synthesis of IP3 and IP4 in the cytosol

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		170835, 1 hit in 52 CRISPR screens

Protein Ontology

More...PROi		PR:P59644
RNActiP59644, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000034570, Expressed in olfactory bulb and 267 other tissues
ExpressionAtlasiP59644, baseline and differential
GenevisibleiP59644, MM

Family and domain databases

Gene3Di3.60.10.10, 1 hit
InterProiView protein in InterPro
IPR036691, Endo/exonu/phosph_ase_sf
IPR005135, Endo/exonuclease/phosphatase
IPR000300, IPPc
IPR041611, SKICH
PfamiView protein in Pfam
PF03372, Exo_endo_phos, 1 hit
PF17751, SKICH, 1 hit
SMARTiView protein in SMART
SM00128, IPPc, 1 hit
SUPFAMiSSF56219, SSF56219, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPI5PA_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P59644
Secondary accession number(s): Q3TDM9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: July 27, 2011
Last modified: April 7, 2021
This is version 142 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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