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Protein

Peroxisomal membrane protein 4

Gene

Pxmp4

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal membrane protein 4
Alternative name(s):
24 kDa peroxisomal intrinsic membrane protein
Gene namesi
Name:Pxmp4
Synonyms:Pmp24
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi628782 Pxmp4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei97 – 117HelicalSequence analysisAdd BLAST21
Transmembranei151 – 171HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00002189342 – 212Peroxisomal membrane protein 4Add BLAST211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi206N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiP59382
PRIDEiP59382

PTM databases

iPTMnetiP59382
PhosphoSitePlusiP59382

Expressioni

Tissue specificityi

Liver.

Gene expression databases

BgeeiENSRNOG00000016975
GenevisibleiP59382 RN

Interactioni

Subunit structurei

Interacts with PEX19.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000022914

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IIYG Eukaryota
ENOG410ZE52 LUCA
GeneTreeiENSGT00390000001562
HOGENOMiHOG000157771
HOVERGENiHBG053773
InParanoidiP59382
KOiK13350
OMAiYTHSRNL
OrthoDBiEOG091G0K56
PhylomeDBiP59382
TreeFamiTF105313

Family and domain databases

InterProiView protein in InterPro
IPR019531 Pmp4
PANTHERiPTHR15460 PTHR15460, 1 hit
PIRSFiPIRSF013674 PXMP4, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P59382-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPPQLRAL LQAVNKLLRQ RRYHAALAVI KGFRNGAVYG VKIRAPHALV
60 70 80 90 100
MTFLFRSGSL QEKLQAILKA TYTHSRNLAC FVFTYKSLQA LQSHVQGGTH
110 120 130 140 150
QMHSFLAAFI GGLLLFGENN NINSQINMYL TSRVLFALCR LGVEKGYIPA
160 170 180 190 200
LKWDPFPLHT AVIWGLVLWL FEYHRPTLQP SLQSSMTYLY EDSNVWHDLS
210
DFLIFNKSRP SK
Length:212
Mass (Da):24,136
Last modified:January 23, 2007 - v2
Checksum:i07D3A5F0A7841A36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY151834 mRNA Translation: AAN72218.1
BC081699 mRNA Translation: AAH81699.1
RefSeqiNP_757377.1, NM_172223.2
UniGeneiRn.7752

Genome annotation databases

EnsembliENSRNOT00000022914; ENSRNOP00000022914; ENSRNOG00000016975
GeneIDi282634
KEGGirno:282634
UCSCiRGD:628782 rat

Similar proteinsi

Entry informationi

Entry nameiPXMP4_RAT
AccessioniPrimary (citable) accession number: P59382
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 28, 2003
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 86 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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