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Entry version 105 (02 Jun 2021)
Sequence version 1 (27 Jan 2003)
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Protein

Cingulin

Gene

Cgn

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-2173791, TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cingulin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cgn
Synonyms:Kiaa1319
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1927237, Cgn

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Tight junction

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000897641 – 1191CingulinAdd BLAST1191

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei84PhosphoserineCombined sources1
Modified residuei89PhosphoserineCombined sources1
Modified residuei90PhosphoserineCombined sources1
Modified residuei92PhosphoserineCombined sources1
Modified residuei129PhosphoserineCombined sources1
Modified residuei131PhosphoserineCombined sources1
Modified residuei134PhosphoserineCombined sources1
Modified residuei149PhosphoserineBy similarity1
Modified residuei159PhosphoserineBy similarity1
Modified residuei208PhosphoserineBy similarity1
Modified residuei211PhosphoserineBy similarity1
Modified residuei250PhosphoserineBy similarity1
Modified residuei268PhosphoserineBy similarity1
Modified residuei326PhosphoserineCombined sources1
Modified residuei339PhosphoserineCombined sources1
Modified residuei448PhosphoserineCombined sources1
Modified residuei567N6-acetyllysineBy similarity1
Modified residuei1163PhosphoserineBy similarity1
Modified residuei1164PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P59242

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P59242

PeptideAtlas

More...
PeptideAtlasi
P59242

PRoteomics IDEntifications database

More...
PRIDEi
P59242

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
281624 [P59242-1]
281625 [P59242-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P59242

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P59242

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Lung, kidney and intestine.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer (By similarity).

Interacts with TJP1/ZO1 and SPEF1 (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000102894

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P59242, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P59242

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 345HeadAdd BLAST345
Regioni1 – 43DisorderedSequence analysisAdd BLAST43
Regioni48 – 61Interaction with TJP1/ZO1By similarityAdd BLAST14
Regioni63 – 130DisorderedSequence analysisAdd BLAST68
Regioni178 – 259DisorderedSequence analysisAdd BLAST82
Regioni872 – 898DisorderedSequence analysisAdd BLAST27
Regioni1148 – 1169DisorderedSequence analysisAdd BLAST22
Regioni1149 – 1191TailAdd BLAST43

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili343 – 1150Sequence analysisAdd BLAST808

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi42 – 56ZIMAdd BLAST15

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi68 – 109Polar residuesSequence analysisAdd BLAST42
Compositional biasi110 – 124Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi201 – 238Basic and acidic residuesSequence analysisAdd BLAST38
Compositional biasi239 – 259Polar residuesSequence analysisAdd BLAST21
Compositional biasi872 – 887Basic and acidic residuesSequence analysisAdd BLAST16

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Deletion of the TJP1/ZO1 interaction motif (ZIM) decreases but does not abolish colocalization with TJP1/ZO1.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the cingulin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R9EI, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P59242

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P59242

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002928, Myosin_tail

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01576, Myosin_tail_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P59242-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MADPRGPVDH GVQIRFITEP EGATEMGTLR RSGRRPARDA RASTYGVAVR
60 70 80 90 100
VQGIAGQPFV VLNSGEKGTD SFGVQIKGGN NRGSPGALSS DSELPENPYS
110 120 130 140 150
QVKGRPATSR SSTSDEEPKD HLNGKLIRSQ SQASLTGLAF MSPSNRSTSL
160 170 180 190 200
LELAPKPTSS INTIDTAPLS SVDSLINKFD SQKGGQVRGR TGRRTRTLPH
210 220 230 240 250
EQRKRSQSLD SRLPRDTREE REHQSANHWT RGTKYDNHVD SSKNPSQKQS
260 270 280 290 300
PFSSFSRSRQ TQDWVLQSFE ETRDPAMVQF KSTPDLLRDQ RETAPPGSAD
310 320 330 340 350
HVKATIYGIL REGSSESEAS VRRKVSLVLE QMQPLGMVSP ASTKALAGQA
360 370 380 390 400
ELTRKMEELQ KKLDEEVKKR QKLEPSRVGL ERQLEEKAEE CHRLQELLER
410 420 430 440 450
RKGEVQQSSK ELQNMKLLLG QEEGLRHGLE AQVKELQLKL KHSQSPDSGK
460 470 480 490 500
ESLLKDLLDT RELLEELLEG KQRVEEQLRL RERELTALKG ALKEEVASHD
510 520 530 540 550
QEVEHVRLQY QRDTEQLRRS MQDATQDHAA LEAERQKMSS LVRELQRELE
560 570 580 590 600
ETSEETGHWQ SMFQKNKEEL RATKQELLQL RMEKEEMEEE LGEKMEVLQR
610 620 630 640 650
DLEQARASTR DTHQVEELKK ELRRTQGELK ELQAEQQNQE VTGRHRNQVL
660 670 680 690 700
EKQLAALREE ADRGRELEQQ NLQLQKTLQQ LRQDCEEASK AKVASETEAM
710 720 730 740 750
MLGQRRATVE TTLRETQEEN DEFRRRILGL EQQLKEARGL AEGGEAVEAR
760 770 780 790 800
LRDKVHRLEV EKQQLEEALN AAQEEEGNLA AAKRALEVRL DEAQRGLARL
810 820 830 840 850
GQEQQALNRA LEEEGKQREA LRRSKAELEE QKRLLNRTVD RLNKELEQIG
860 870 880 890 900
DDSKLALQQL QAQMEDYKEK ARKEVADAQR QAKDWASEAE KNSGGLSRLQ
910 920 930 940 950
DELQRLRQAL QTSQAERDTA RLDKELLAQR LQGLEQEAEN KKRFQDDKAR
960 970 980 990 1000
QLKSLEEKVS RLEAELDEEK NTVELLTDRV NRGRDQVDQL RTELMQERSA
1010 1020 1030 1040 1050
RQDLECDKIS LERQNKDLKT RLASSEGFQK PSASLSQLES QNQLLQERLQ
1060 1070 1080 1090 1100
AEEREKTVLQ STNRKLERRV KELSIQIDDE RQHVNDQKDQ LTLRVKALKR
1110 1120 1130 1140 1150
QVDEAEEEIE RLDSLRKKAQ RELEEQHEVN EQLQARIKSL EKDAWRKASR
1160 1170 1180 1190
SAAESALKQE GLSSDEEFDN VYDPSSIASL LTESNLQTSS C
Length:1,191
Mass (Da):136,447
Last modified:January 27, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i43EA20F49AF5E7D9
GO
Isoform 2 (identifier: P59242-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     337-344: Missing.

Show »
Length:1,183
Mass (Da):135,645
Checksum:i2C04CEE9BE010EB9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A5F8MPT6A0A5F8MPT6_MOUSE
Cingulin
Cgn
1,192Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9QMC1E9QMC1_MOUSE
Cingulin
Cgn
1,191Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YUW7D3YUW7_MOUSE
Cingulin
Cgn
1,183Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JFG0A0A0G2JFG0_MOUSE
Cingulin
Cgn
403Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JEK8A0A0G2JEK8_MOUSE
Cingulin
Cgn
448Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH42459 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH52941 differs from that shown. Reason: Frameshift.Curated
The sequence AAH52941 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated
The sequence AAH64474 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAD32426 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti430E → K in AAH52941 (PubMed:15489334).Curated1
Sequence conflicti441K → M in AAH52941 (PubMed:15489334).Curated1
Sequence conflicti573T → A in AAH52941 (PubMed:15489334).Curated1
Sequence conflicti646R → Q in BAD32426 (PubMed:15368895).Curated1
Sequence conflicti701M → V in BAD32426 (PubMed:15368895).Curated1
Sequence conflicti773Q → R in BAD32426 (PubMed:15368895).Curated1
Sequence conflicti1173D → N in AAH52941 (PubMed:15489334).Curated1
Sequence conflicti1173D → N in AAH64474 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_037041337 – 344Missing in isoform 2. 1 Publication8

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK173148 mRNA Translation: BAD32426.1 Different initiation.
BC042459 mRNA Translation: AAH42459.1 Different initiation.
BC052941 mRNA Translation: AAH52941.1 Sequence problems.
BC064474 mRNA Translation: AAH64474.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS50984.2 [P59242-1]
CCDS79976.2 [P59242-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK173148 mRNA Translation: BAD32426.1 Different initiation.
BC042459 mRNA Translation: AAH42459.1 Different initiation.
BC052941 mRNA Translation: AAH52941.1 Sequence problems.
BC064474 mRNA Translation: AAH64474.1 Different initiation.
CCDSiCCDS50984.2 [P59242-1]
CCDS79976.2 [P59242-2]

3D structure databases

SMRiP59242
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000102894

PTM databases

iPTMnetiP59242
PhosphoSitePlusiP59242

Proteomic databases

MaxQBiP59242
PaxDbiP59242
PeptideAtlasiP59242
PRIDEiP59242
ProteomicsDBi281624 [P59242-1]
281625 [P59242-2]

Organism-specific databases

MGIiMGI:1927237, Cgn

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiENOG502R9EI, Eukaryota
InParanoidiP59242
PhylomeDBiP59242

Enzyme and pathway databases

ReactomeiR-MMU-2173791, TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Cgn, mouse

Protein Ontology

More...
PROi
PR:P59242
RNActiP59242, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Family and domain databases

InterProiView protein in InterPro
IPR002928, Myosin_tail
PfamiView protein in Pfam
PF01576, Myosin_tail_1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCING_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P59242
Secondary accession number(s): Q05BC4, Q69ZM0, Q6P2K0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 27, 2003
Last sequence update: January 27, 2003
Last modified: June 2, 2021
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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