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Entry version 140 (07 Oct 2020)
Sequence version 1 (17 Jan 2003)
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Protein

Scavenger receptor class F member 2

Gene

Scarf2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL).

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor
Biological processCell adhesion

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Scavenger receptor class F member 2
Alternative name(s):
Scavenger receptor expressed by endothelial cells 2 protein
Short name:
SREC-II
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Scarf2
Synonyms:Srec2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1858430, Scarf2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini34 – 433ExtracellularSequence analysisAdd BLAST400
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei434 – 454HelicalSequence analysisAdd BLAST21
Topological domaini455 – 833CytoplasmicSequence analysisAdd BLAST379

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 33Sequence analysisAdd BLAST33
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000774034 – 833Scavenger receptor class F member 2Add BLAST800

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi67 ↔ 78PROSITE-ProRule annotation
Disulfide bondi72 ↔ 90PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi75N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi92 ↔ 101PROSITE-ProRule annotation
Disulfide bondi118 ↔ 126PROSITE-ProRule annotation
Disulfide bondi120 ↔ 133PROSITE-ProRule annotation
Disulfide bondi135 ↔ 144PROSITE-ProRule annotation
Disulfide bondi148 ↔ 155PROSITE-ProRule annotation
Disulfide bondi150 ↔ 162PROSITE-ProRule annotation
Disulfide bondi164 ↔ 173PROSITE-ProRule annotation
Disulfide bondi177 ↔ 185PROSITE-ProRule annotation
Disulfide bondi179 ↔ 192PROSITE-ProRule annotation
Disulfide bondi194 ↔ 203PROSITE-ProRule annotation
Disulfide bondi207 ↔ 214PROSITE-ProRule annotation
Disulfide bondi209 ↔ 221PROSITE-ProRule annotation
Disulfide bondi223 ↔ 232PROSITE-ProRule annotation
Disulfide bondi236 ↔ 243PROSITE-ProRule annotation
Disulfide bondi238 ↔ 250PROSITE-ProRule annotation
Disulfide bondi252 ↔ 261PROSITE-ProRule annotation
Glycosylationi302N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi357N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi368 ↔ 376PROSITE-ProRule annotation
Disulfide bondi371 ↔ 383PROSITE-ProRule annotation
Disulfide bondi385 ↔ 394PROSITE-ProRule annotation
Glycosylationi395N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei538PhosphoserineCombined sources1
Modified residuei600PhosphoserineBy similarity1
Modified residuei615PhosphotyrosineCombined sources1
Modified residuei638PhosphoserineCombined sources1
Modified residuei640PhosphoserineCombined sources1
Modified residuei695PhosphoserineCombined sources1
Modified residuei712PhosphothreonineCombined sources1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
non-CPTAC-3498

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P59222

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P59222

PeptideAtlas

More...
PeptideAtlasi
P59222

PRoteomics IDEntifications database

More...
PRIDEi
P59222

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
P59222, 4 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P59222

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P59222

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P59222

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000012017, Expressed in vault of skull and 194 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P59222, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P59222, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homophilic and heterophilic interaction via its extracellular domain.

Interacts with SCARF1. The heterophilic interaction with SCARF1, which is stronger than the homophilic interaction with itself, is suppressed by the presence of SCARF1 ligand such as Ac-LDL.

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
230229, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000012161

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P59222, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P59222

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini63 – 102EGF-like 1PROSITE-ProRule annotationAdd BLAST40
Domaini114 – 145EGF-like 2PROSITE-ProRule annotationAdd BLAST32
Domaini140 – 174EGF-like 3PROSITE-ProRule annotationAdd BLAST35
Domaini175 – 204EGF-like 4PROSITE-ProRule annotationAdd BLAST30
Domaini205 – 233EGF-like 5PROSITE-ProRule annotationAdd BLAST29
Domaini228 – 262EGF-like 6PROSITE-ProRule annotationAdd BLAST35
Domaini364 – 395EGF-like 7PROSITE-ProRule annotationAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi639 – 714Pro-richAdd BLAST76

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1218, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183101

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_017821_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P59222

Identification of Orthologs from Complete Genome Data

More...
OMAi
CENVCLC

Database of Orthologous Groups

More...
OrthoDBi
110992at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P59222

TreeFam database of animal gene trees

More...
TreeFami
TF332598

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000742, EGF-like_dom
IPR009030, Growth_fac_rcpt_cys_sf
IPR002049, Laminin_EGF
IPR033327, Scarf2
IPR042635, SREC1/2

The PANTHER Classification System

More...
PANTHERi
PTHR24043, PTHR24043, 1 hit
PTHR24043:SF5, PTHR24043:SF5, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181, EGF, 8 hits
SM00180, EGF_Lam, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57184, SSF57184, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022, EGF_1, 7 hits
PS01186, EGF_2, 4 hits
PS50026, EGF_3, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P59222-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGAGSRGAG PARRQGARGL GLLLLLWLLP GLAAPQDLNP RGRNVCRTPG
60 70 80 90 100
SQVLTCCAGW RQLGDECGIA VCEGNSTCSE NEVCVRPGEC RCRHGYFGAN
110 120 130 140 150
CDTKCPRQFW GPDCKERCSC HPHGQCEDVT GQCTCHARRW GARCEHACQC
160 170 180 190 200
QHGTCHPRSG ACRCEPGWWG AQCASACYCS ATSRCDPQTG ACLCHVGWWG
210 220 230 240 250
RSCNNQCACN SSPCEQQSGR CQCRERMFGA RCDRYCQCSH GRCHPVDGTC
260 270 280 290 300
ACDPGYRGKY CREPCPAGFY GPGCRRRCGQ CKGQQPCTVV EGRCLTCEPG
310 320 330 340 350
WNGTKCDQPC ATGFYGEGCG HRCPPCRDGH ACNHVTGKCT HCNAGWIGDR
360 370 380 390 400
CETKCSNGTY GEDCAFVCSD CGSGHCDFQS GRCLCSPGVH GPHCNVTCPA
410 420 430 440 450
GLHGVDCAQA CSCHEESCDP VTGACHLETN QRKGVMGAGA LLTLLLGLLL
460 470 480 490 500
SLLGCCCACR GKDSARRELT LGRKKAPQRF CGSFSRISMK LPRIPLRRQK
510 520 530 540 550
LPKVVVAHHD LDNTLNCSFL DPPSGLEQPS PSWSSRASFS SFDTTDEGPV
560 570 580 590 600
YCVPHEEATA DSRDLEATAA LTEVAAVSLE PTGTSTPGEE AAVLPASSDS
610 620 630 640 650
ERSASSVEGP SGALYARVAR REARPARTRN EAGGLSLSPS PERRKPPPPD
660 670 680 690 700
PATKPKVSWI HGKHSAAAAA PSPPPAGRKA APSPSGRKRT PSNSSVQPPG
710 720 730 740 750
LTEEAPGPAS PTPPRARARG RGLGLSEPTD AGGPPRSAPE AASMLAAELR
760 770 780 790 800
DKTRSLGRAE KPPPPQKAKR SVLPAATVRT ASASEASGSE KAAASAPAPE
810 820 830
TPRKKTPIQK PPRKKSREAA GEPSRAGTAP GAS
Length:833
Mass (Da):87,871
Last modified:January 17, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i51EADEEAACAFF005
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A338P7B2A0A338P7B2_MOUSE
Scavenger receptor class F member 2
Scarf2
566Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A338P7B0A0A338P7B0_MOUSE
Scavenger receptor class F member 2
Scarf2
141Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF522197 mRNA Translation: AAN45862.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS28010.1

NCBI Reference Sequences

More...
RefSeqi
NP_722485.1, NM_153790.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000012161; ENSMUSP00000012161; ENSMUSG00000012017

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
224024

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:224024

UCSC genome browser

More...
UCSCi
uc007ymd.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF522197 mRNA Translation: AAN45862.1
CCDSiCCDS28010.1
RefSeqiNP_722485.1, NM_153790.3

3D structure databases

SMRiP59222
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi230229, 3 interactors
STRINGi10090.ENSMUSP00000012161

PTM databases

GlyGeniP59222, 4 sites
iPTMnetiP59222
PhosphoSitePlusiP59222
SwissPalmiP59222

Proteomic databases

CPTACinon-CPTAC-3498
jPOSTiP59222
PaxDbiP59222
PeptideAtlasiP59222
PRIDEiP59222

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
51072, 100 antibodies

Genome annotation databases

EnsembliENSMUST00000012161; ENSMUSP00000012161; ENSMUSG00000012017
GeneIDi224024
KEGGimmu:224024
UCSCiuc007ymd.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
91179
MGIiMGI:1858430, Scarf2

Phylogenomic databases

eggNOGiKOG1218, Eukaryota
GeneTreeiENSGT00950000183101
HOGENOMiCLU_017821_1_0_1
InParanoidiP59222
OMAiCENVCLC
OrthoDBi110992at2759
PhylomeDBiP59222
TreeFamiTF332598

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
224024, 0 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Scarf2, mouse

Protein Ontology

More...
PROi
PR:P59222
RNActiP59222, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000012017, Expressed in vault of skull and 194 other tissues
ExpressionAtlasiP59222, baseline and differential
GenevisibleiP59222, MM

Family and domain databases

InterProiView protein in InterPro
IPR000742, EGF-like_dom
IPR009030, Growth_fac_rcpt_cys_sf
IPR002049, Laminin_EGF
IPR033327, Scarf2
IPR042635, SREC1/2
PANTHERiPTHR24043, PTHR24043, 1 hit
PTHR24043:SF5, PTHR24043:SF5, 1 hit
SMARTiView protein in SMART
SM00181, EGF, 8 hits
SM00180, EGF_Lam, 6 hits
SUPFAMiSSF57184, SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00022, EGF_1, 7 hits
PS01186, EGF_2, 4 hits
PS50026, EGF_3, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSREC2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P59222
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: January 17, 2003
Last modified: October 7, 2020
This is version 140 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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