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Protein

Endoribonuclease YbeY

Gene

YBEY

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Single strand-specific metallo-endoribonuclease involved in rRNA maturation.1 Publication

Miscellaneous

A protein of the expected size has been detected by antibody binding and Western blot in at least one of the analyzed tissues or cells.1 Publication

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+By similarityNote: Binds 1 zinc ion.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi118Zinc; catalyticBy similarity1
Metal bindingi122Zinc; catalyticBy similarity1
Metal bindingi128Zinc; catalyticBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • endoribonuclease activity Source: UniProtKB
  • metal ion binding Source: UniProtKB-KW
  • metalloendopeptidase activity Source: InterPro

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Endoribonuclease YbeYCurated (EC:3.1.-.-1 Publication)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:YBEY
Synonyms:C21orf57
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000182362.13

Human Gene Nomenclature Database

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HGNCi
HGNC:1299 YBEY

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
617461 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P58557

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi55R → E: No endonuclease activity. 1 Publication1
Mutagenesisi90D → R: No endonuclease activity. 1 Publication1
Mutagenesisi118H → A: No endonuclease activity. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
54059

Open Targets

More...
OpenTargetsi
ENSG00000182362

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25852

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
YBEY

Domain mapping of disease mutations (DMDM)

More...
DMDMi
47117865

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001025781 – 167Endoribonuclease YbeYAdd BLAST167

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P58557

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P58557

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P58557

PeptideAtlas

More...
PeptideAtlasi
P58557

PRoteomics IDEntifications database

More...
PRIDEi
P58557

ProteomicsDB human proteome resource

More...
ProteomicsDBi
57090
57091 [P58557-2]
57092 [P58557-3]
57093 [P58557-4]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P58557-1 [P58557-1]
P58557-3 [P58557-3]

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000182362 Expressed in 200 organ(s), highest expression level in left testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_C21orf57

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P58557 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA016593
HPA018162

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119869, 75 interactors

Protein interaction database and analysis system

More...
IntActi
P58557, 3 interactors

Molecular INTeraction database

More...
MINTi
P58557

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000329614

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
P58557

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P58557

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the endoribonuclease YbeY family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IRPH Eukaryota
COG0319 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153864

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000132869

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG051234

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P58557

Identification of Orthologs from Complete Genome Data

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OMAi
AAHGLCH

Database of Orthologous Groups

More...
OrthoDBi
EOG091G148Y

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P58557

TreeFam database of animal gene trees

More...
TreeFami
TF332551

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.40.390.30, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00009 Endoribonucl_YbeY, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR023091 MetalPrtase_cat_dom_sf_prd
IPR002036 YbeY
IPR020549 YbeY_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02130 UPF0054, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00043 TIGR00043, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01306 UPF0054, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform A (identifier: P58557-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSLVIRNLQR VIPIRRAPLR SKIEIVRRIL GVQKFDLGII CVDNKNIQHI
60 70 80 90 100
NRIYRDRNVP TDVLSFPFHE HLKAGEFPQP DFPDDYNLGD IFLGVEYIFH
110 120 130 140 150
QCKENEDYND VLTVTATHGL CHLLGFTHGT EAEWQQMFQK EKAVLDELGR
160
RTGTRLQPLT RGLFGGS
Length:167
Mass (Da):19,298
Last modified:May 10, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i62C42B31B6BA5F26
GO
Isoform B (identifier: P58557-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     71-113: Missing.

Show »
Length:124
Mass (Da):14,269
Checksum:iDCCA3CE5A38A85CE
GO
Isoform C (identifier: P58557-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     26-70: Missing.

Show »
Length:122
Mass (Da):13,966
Checksum:i2CBE385901D5AA61
GO
Isoform D (identifier: P58557-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     26-113: Missing.

Show »
Length:79
Mass (Da):8,936
Checksum:iC4EB042CEBEBD619
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK74138 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated
The sequence AAK74139 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAK74140 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated
The sequence AAK74141 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_00672226 – 113Missing in isoform D. 1 PublicationAdd BLAST88
Alternative sequenceiVSP_00672126 – 70Missing in isoform C. 1 PublicationAdd BLAST45
Alternative sequenceiVSP_00672371 – 113Missing in isoform B. 1 PublicationAdd BLAST43

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY040873 mRNA Translation: AAK74138.1 Sequence problems.
AY040874 mRNA Translation: AAK74139.1 Different initiation.
AY040875 mRNA Translation: AAK74140.1 Sequence problems.
AY040876 mRNA Translation: AAK74141.1 Sequence problems.
AP000471 Genomic DNA No translation available.
CH471079 Genomic DNA Translation: EAX09288.1
CH471079 Genomic DNA Translation: EAX09290.1
CH471079 Genomic DNA Translation: EAX09291.1
CH471079 Genomic DNA Translation: EAX09293.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33591.1 [P58557-1]
CCDS82685.1 [P58557-3]
CCDS82686.1 [P58557-4]
CCDS82687.1 [P58557-2]

NCBI Reference Sequences

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RefSeqi
NP_001300951.1, NM_001314022.1 [P58557-2]
NP_001300952.1, NM_001314023.1 [P58557-3]
NP_001300953.1, NM_001314024.1 [P58557-4]
NP_001300954.1, NM_001314025.1 [P58557-1]
NP_001300955.1, NM_001314026.1
NP_478061.1, NM_058181.2 [P58557-1]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.474066

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000329319; ENSP00000329614; ENSG00000182362 [P58557-1]
ENST00000339195; ENSP00000340675; ENSG00000182362 [P58557-2]
ENST00000397691; ENSP00000380805; ENSG00000182362 [P58557-1]
ENST00000397692; ENSP00000380806; ENSG00000182362 [P58557-4]
ENST00000397694; ENSP00000380808; ENSG00000182362 [P58557-3]
ENST00000397701; ENSP00000380813; ENSG00000182362 [P58557-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
54059

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54059

UCSC genome browser

More...
UCSCi
uc002ziv.4 human [P58557-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY040873 mRNA Translation: AAK74138.1 Sequence problems.
AY040874 mRNA Translation: AAK74139.1 Different initiation.
AY040875 mRNA Translation: AAK74140.1 Sequence problems.
AY040876 mRNA Translation: AAK74141.1 Sequence problems.
AP000471 Genomic DNA No translation available.
CH471079 Genomic DNA Translation: EAX09288.1
CH471079 Genomic DNA Translation: EAX09290.1
CH471079 Genomic DNA Translation: EAX09291.1
CH471079 Genomic DNA Translation: EAX09293.1
CCDSiCCDS33591.1 [P58557-1]
CCDS82685.1 [P58557-3]
CCDS82686.1 [P58557-4]
CCDS82687.1 [P58557-2]
RefSeqiNP_001300951.1, NM_001314022.1 [P58557-2]
NP_001300952.1, NM_001314023.1 [P58557-3]
NP_001300953.1, NM_001314024.1 [P58557-4]
NP_001300954.1, NM_001314025.1 [P58557-1]
NP_001300955.1, NM_001314026.1
NP_478061.1, NM_058181.2 [P58557-1]
UniGeneiHs.474066

3D structure databases

ProteinModelPortaliP58557
SMRiP58557
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119869, 75 interactors
IntActiP58557, 3 interactors
MINTiP58557
STRINGi9606.ENSP00000329614

Polymorphism and mutation databases

BioMutaiYBEY
DMDMi47117865

Proteomic databases

EPDiP58557
MaxQBiP58557
PaxDbiP58557
PeptideAtlasiP58557
PRIDEiP58557
ProteomicsDBi57090
57091 [P58557-2]
57092 [P58557-3]
57093 [P58557-4]
TopDownProteomicsiP58557-1 [P58557-1]
P58557-3 [P58557-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000329319; ENSP00000329614; ENSG00000182362 [P58557-1]
ENST00000339195; ENSP00000340675; ENSG00000182362 [P58557-2]
ENST00000397691; ENSP00000380805; ENSG00000182362 [P58557-1]
ENST00000397692; ENSP00000380806; ENSG00000182362 [P58557-4]
ENST00000397694; ENSP00000380808; ENSG00000182362 [P58557-3]
ENST00000397701; ENSP00000380813; ENSG00000182362 [P58557-1]
GeneIDi54059
KEGGihsa:54059
UCSCiuc002ziv.4 human [P58557-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54059
DisGeNETi54059
EuPathDBiHostDB:ENSG00000182362.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
YBEY

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0027793
HGNCiHGNC:1299 YBEY
HPAiHPA016593
HPA018162
MIMi617461 gene
neXtProtiNX_P58557
OpenTargetsiENSG00000182362
PharmGKBiPA25852

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IRPH Eukaryota
COG0319 LUCA
GeneTreeiENSGT00940000153864
HOGENOMiHOG000132869
HOVERGENiHBG051234
InParanoidiP58557
OMAiAAHGLCH
OrthoDBiEOG091G148Y
PhylomeDBiP58557
TreeFamiTF332551

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
54059

Protein Ontology

More...
PROi
PR:P58557

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000182362 Expressed in 200 organ(s), highest expression level in left testis
CleanExiHS_C21orf57
GenevisibleiP58557 HS

Family and domain databases

Gene3Di3.40.390.30, 1 hit
HAMAPiMF_00009 Endoribonucl_YbeY, 1 hit
InterProiView protein in InterPro
IPR023091 MetalPrtase_cat_dom_sf_prd
IPR002036 YbeY
IPR020549 YbeY_CS
PfamiView protein in Pfam
PF02130 UPF0054, 1 hit
TIGRFAMsiTIGR00043 TIGR00043, 1 hit
PROSITEiView protein in PROSITE
PS01306 UPF0054, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYBEY_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P58557
Secondary accession number(s): B7WPA9, B7WPF7, D3DSN2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: May 10, 2004
Last modified: December 5, 2018
This is version 124 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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