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Entry version 145 (07 Apr 2021)
Sequence version 3 (01 May 2013)
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Protein

PAX3- and PAX7-binding protein 1

Gene

Paxbp1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processMyogenesis, Transcription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PAX3- and PAX7-binding protein 1
Short name:
PAX3/7BP
Alternative name(s):
GC-rich sequence DNA-binding factor 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Paxbp1
Synonyms:Gcfc, Gcfc1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1914617, Paxbp1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000874401 – 919PAX3- and PAX7-binding protein 1Add BLAST919

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei16PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki151Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linki151Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Modified residuei160PhosphoserineBy similarity1
Modified residuei193PhosphoserineBy similarity1
Modified residuei264PhosphoserineBy similarity1
Modified residuei297PhosphoserineCombined sources1
Modified residuei559PhosphoserineCombined sources1
Modified residuei560PhosphoserineCombined sources1
Modified residuei565PhosphothreonineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P58501

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P58501

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P58501

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P58501

PeptideAtlas

More...
PeptideAtlasi
P58501

PRoteomics IDEntifications database

More...
PRIDEi
P58501

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
287786 [P58501-1]
287787 [P58501-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P58501

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P58501

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed in all tissues tested including skeletal muscle. Expressed in primary myoblasts.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000022974, Expressed in lens of camera-type eye and 327 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P58501, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P58501, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PAX3 and PAX7.

Interacts with WDR5; associates with a histone methyltransferase (HMT) complex composed at least of RBBP5, ASH2L, SET1, SET2 and KMT2A/MLL1, KMT2D/MLL2, KMT2C/MLL3 and KMT2B/MLL4 through direct interaction with WDR5.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
212138, 19 interactors

Protein interaction database and analysis system

More...
IntActi
P58501, 2 interactors

Molecular INTeraction database

More...
MINTi
P58501

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000113835

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P58501, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P58501

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni380 – 560Necessary and sufficient for interaction with PAX71 PublicationAdd BLAST181

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GCF family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2136, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000455

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010846_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P58501

Identification of Orthologs from Complete Genome Data

More...
OMAi
STQRTKN

Database of Orthologous Groups

More...
OrthoDBi
1217358at2759

TreeFam database of animal gene trees

More...
TreeFami
TF315109

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012890, GCFC2-like
IPR022783, GCFC_dom

The PANTHER Classification System

More...
PANTHERi
PTHR12214, PTHR12214, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07842, GCFC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P58501-1) [UniParc]FASTAAdd to basket
Also known as: A

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFRKARRVNV RKRNDSEEEE RERDEEQEPP PLLPPPASGE EPGPGGGDRA
60 70 80 90 100
PAGESLLGPG PLPPPPSAHH PGLGAEAGGG ISGGAEPGNG LKPRKRPREN
110 120 130 140 150
KEVPRASLLS FQDEEEENEE VFKVKKSSYS KKIVKLLKKE YKEDLEKSKI
160 170 180 190 200
KTELNTAADS DQPLDKTCHA KDTNPEDGVV ISEHGEDEMD MESEKEEEKP
210 220 230 240 250
KAGGAFSNAL SSLNVLRPGE IPDAAFIHAA RKKRQLAREL GDFTPHDSEP
260 270 280 290 300
GKGRLVREDE NDASDDEDDD EKRRIVFSVK EKSQRQKIAE EIGIEGSDDD
310 320 330 340 350
ALVTGEQDEE LSRWEQEQIR KGINIPQVQA SQPSEVNVYY QNTYQTMPYG
360 370 380 390 400
ASYGIPYSYT AYGSSDAKSQ KTDNTVPFKT PSNEMAPVTI DLVKRQLKDR
410 420 430 440 450
LDSMKELHKT NQQQHEKHLQ SRVDSTRAIE RLEGSSGGIG ERYKFLQEMR
460 470 480 490 500
GYVQDLLECF SEKVPLINEL ESAIHQLYKQ RASRLVQRRQ DDIKDESSEF
510 520 530 540 550
SSHSNKALMA PNLDSFGRDR ALYQEHAKRR IAEREARRTR RRQAREQTGQ
560 570 580 590 600
MADHLEGLSS DDEETSTDIT NFNLEKDRIL KESSKVFEDV LESFYSIDCI
610 620 630 640 650
KAQFEAWRSK YYMSYKDAYI GLCLPKLFNP LIRLQLLTWT PLEAKCRDFE
660 670 680 690 700
TMLWFESLLF YGCEDREQEK DEADVALLPT IVEKVILPKL TVIAETMWDP
710 720 730 740 750
FSTTQTSRMV GITMKLINGY PSVVNADNKN TQVYLKALLL RMRRTLDDDV
760 770 780 790 800
FMPLYPKNVL ENKNSGPYLF FQRQFWSSVK LLGNFLQWYG IFSNKTLQEL
810 820 830 840 850
SIDGLLNRYI LMAFQNSEYG DDSIRKAQNV INCFPKQWFV NLKGERTISQ
860 870 880 890 900
LENFCRYLVH LADTIYRNSI GCSDVEKRNA RENIKQIVKL LASVRALDHA
910
ISVASDHNVK EVKSLIEGK
Length:919
Mass (Da):104,836
Last modified:May 1, 2013 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB87DB648782A1CB6
GO
Isoform 2 (identifier: P58501-2) [UniParc]FASTAAdd to basket
Also known as: D

The sequence of this isoform differs from the canonical sequence as follows:
     505-513: NKALMAPNL → SQSILKIKL
     514-919: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.Curated
Show »
Length:513
Mass (Da):57,526
Checksum:i86383AAC32552328
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6YY19F6YY19_MOUSE
PAX3- and PAX7-binding protein 1
Paxbp1 Gcfc1
450Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6YS88F6YS88_MOUSE
PAX3- and PAX7-binding protein 1
Paxbp1 Gcfc1
36Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH14838 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated
The sequence AAH27145 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence AAH27145 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated
The sequence BAB24988 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated
The sequence BAB27645 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti70H → N in AAK68725 (PubMed:11707072).Curated1
Sequence conflicti70H → N in AAK68726 (PubMed:11707072).Curated1
Sequence conflicti82S → P in AAK68725 (PubMed:11707072).Curated1
Sequence conflicti82S → P in AAK68726 (PubMed:11707072).Curated1
Sequence conflicti505 – 506NK → SQ in AAK68725 (PubMed:11707072).Curated2
Isoform 2 (identifier: P58501-2)
Sequence conflicti510K → E in BAB24988 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_004268505 – 513NKALMAPNL → SQSILKIKL in isoform 2. 3 Publications9
Alternative sequenceiVSP_004269514 – 919Missing in isoform 2. 3 PublicationsAdd BLAST406

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC141885 Genomic DNA No translation available.
AY033907 mRNA Translation: AAK68725.1
AY033908 mRNA Translation: AAK68726.1
AK007365 mRNA Translation: BAB24988.2 Sequence problems.
AK011477 mRNA Translation: BAB27645.2 Sequence problems.
BC014838 mRNA Translation: AAH14838.2 Sequence problems.
BC027145 mRNA Translation: AAH27145.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS49908.1 [P58501-1]

NCBI Reference Sequences

More...
RefSeqi
NP_080386.3, NM_026110.2 [P58501-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000118522; ENSMUSP00000113835; ENSMUSG00000022974 [P58501-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
67367

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:67367

UCSC genome browser

More...
UCSCi
uc012aih.1, mouse [P58501-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC141885 Genomic DNA No translation available.
AY033907 mRNA Translation: AAK68725.1
AY033908 mRNA Translation: AAK68726.1
AK007365 mRNA Translation: BAB24988.2 Sequence problems.
AK011477 mRNA Translation: BAB27645.2 Sequence problems.
BC014838 mRNA Translation: AAH14838.2 Sequence problems.
BC027145 mRNA Translation: AAH27145.1 Sequence problems.
CCDSiCCDS49908.1 [P58501-1]
RefSeqiNP_080386.3, NM_026110.2 [P58501-1]

3D structure databases

SMRiP58501
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi212138, 19 interactors
IntActiP58501, 2 interactors
MINTiP58501
STRINGi10090.ENSMUSP00000113835

PTM databases

iPTMnetiP58501
PhosphoSitePlusiP58501

Proteomic databases

EPDiP58501
jPOSTiP58501
MaxQBiP58501
PaxDbiP58501
PeptideAtlasiP58501
PRIDEiP58501
ProteomicsDBi287786 [P58501-1]
287787 [P58501-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
22645, 129 antibodies

The DNASU plasmid repository

More...
DNASUi
67367

Genome annotation databases

EnsembliENSMUST00000118522; ENSMUSP00000113835; ENSMUSG00000022974 [P58501-1]
GeneIDi67367
KEGGimmu:67367
UCSCiuc012aih.1, mouse [P58501-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
94104
MGIiMGI:1914617, Paxbp1

Phylogenomic databases

eggNOGiKOG2136, Eukaryota
GeneTreeiENSGT00390000000455
HOGENOMiCLU_010846_3_0_1
InParanoidiP58501
OMAiSTQRTKN
OrthoDBi1217358at2759
TreeFamiTF315109

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
67367, 6 hits in 53 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Paxbp1, mouse

Protein Ontology

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PROi
PR:P58501
RNActiP58501, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000022974, Expressed in lens of camera-type eye and 327 other tissues
ExpressionAtlasiP58501, baseline and differential
GenevisibleiP58501, MM

Family and domain databases

InterProiView protein in InterPro
IPR012890, GCFC2-like
IPR022783, GCFC_dom
PANTHERiPTHR12214, PTHR12214, 1 hit
PfamiView protein in Pfam
PF07842, GCFC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPAXB1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P58501
Secondary accession number(s): E9QNN9
, Q78XY2, Q8R2W3, Q9CRB7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 19, 2001
Last sequence update: May 1, 2013
Last modified: April 7, 2021
This is version 145 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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