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Entry version 151 (17 Jun 2020)
Sequence version 2 (10 Jul 2007)
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Protein

Zinc finger protein 121

Gene

ZNF121

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri88 – 110C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri116 – 138C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri144 – 166C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri172 – 194C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri200 – 222C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri228 – 250C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri256 – 278C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri284 – 306C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri312 – 334C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri340 – 362C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri368 – 390C2H2-type 11PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 121
Alternative name(s):
Zinc finger protein 20
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF121
Synonyms:ZNF20
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000197961.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:12904 ZNF121

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
194628 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P58317

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000197961

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37493

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P58317 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF121

Domain mapping of disease mutations (DMDM)

More...
DMDMi
152031766

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000474081 – 390Zinc finger protein 121Add BLAST390

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P58317

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P58317

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P58317

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P58317

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P58317

PeptideAtlas

More...
PeptideAtlasi
P58317

PRoteomics IDEntifications database

More...
PRIDEi
P58317

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
57059

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P58317

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P58317

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000197961 Expressed in material anatomical entity and 200 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P58317 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P58317 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000197961 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
113474, 16 interactors

Protein interaction database and analysis system

More...
IntActi
P58317, 21 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000326967

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P58317 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P58317

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri88 – 110C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri116 – 138C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri144 – 166C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri172 – 194C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri200 – 222C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri228 – 250C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri256 – 278C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri284 – 306C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri312 – 334C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri340 – 362C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri368 – 390C2H2-type 11PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163151

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_44_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P58317

Identification of Orthologs from Complete Genome Data

More...
OMAi
QPNRITH

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P58317

TreeFam database of animal gene trees

More...
TreeFami
TF341966

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096 zf-C2H2, 9 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355 ZnF_C2H2, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667 SSF57667, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 9 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P58317-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEIHNGGEL CDFMENGEIF SEHSCLNAHM GTENTGDTYD CDEYGENFPM
60 70 80 90 100
LHNSAPAGET LSVLNQCRKA FSLPPNVHQR TWIGDKSFEY SDCEEAFVDQ
110 120 130 140 150
SHLQANRITH NGETLYEQKQ CGRAFTYSTS HAVSVKMHTV EKPYECKECG
160 170 180 190 200
KFFRYSSYLN SHMRTHTGEK PYECKECGKC FTVSSHLVEH VRIHTGEKPY
210 220 230 240 250
QCKECGRAFA GRSGLTKHVR IHTGEKPYEC NECGKAYNRF YLLTEHFKTH
260 270 280 290 300
TEEKPFECKV CGKSFRSSSC LKNHFRIHTG IKPYKCKECG KAFTVSSSLH
310 320 330 340 350
NHVKIHTGEK PYECKDCGKA FATSSQLIEH IRTHTGEKPY ICKECGKTFR
360 370 380 390
ASSHLQKHVR IHTGEKPYIC NECGKAYNRF YLLTKHLKTH
Length:390
Mass (Da):44,694
Last modified:July 10, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5E824D279B5235EE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EQI1K7EQI1_HUMAN
Zinc finger protein 121
ZNF121
151Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti96 – 97AF → NS in M99593 (PubMed:8468057).Curated2
Sequence conflicti212R → C in M99593 (PubMed:8468057).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC008759 Genomic DNA No translation available.
M99593 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32902.1
CCDS77228.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A46017

NCBI Reference Sequences

More...
RefSeqi
NP_001008727.1, NM_001008727.3
NP_001295198.1, NM_001308269.1
XP_016882728.1, XM_017027239.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000320451; ENSP00000326967; ENSG00000197961
ENST00000586602; ENSP00000468643; ENSG00000197961

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7675

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7675

UCSC genome browser

More...
UCSCi
uc010dwt.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008759 Genomic DNA No translation available.
M99593 Genomic DNA No translation available.
CCDSiCCDS32902.1
CCDS77228.1
PIRiA46017
RefSeqiNP_001008727.1, NM_001008727.3
NP_001295198.1, NM_001308269.1
XP_016882728.1, XM_017027239.1

3D structure databases

SMRiP58317
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi113474, 16 interactors
IntActiP58317, 21 interactors
STRINGi9606.ENSP00000326967

PTM databases

iPTMnetiP58317
PhosphoSitePlusiP58317

Polymorphism and mutation databases

BioMutaiZNF121
DMDMi152031766

Proteomic databases

EPDiP58317
jPOSTiP58317
MassIVEiP58317
MaxQBiP58317
PaxDbiP58317
PeptideAtlasiP58317
PRIDEiP58317
ProteomicsDBi57059

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
25051 42 antibodies

The DNASU plasmid repository

More...
DNASUi
7675

Genome annotation databases

EnsembliENST00000320451; ENSP00000326967; ENSG00000197961
ENST00000586602; ENSP00000468643; ENSG00000197961
GeneIDi7675
KEGGihsa:7675
UCSCiuc010dwt.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7675
EuPathDBiHostDB:ENSG00000197961.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF121
HGNCiHGNC:12904 ZNF121
HPAiENSG00000197961 Low tissue specificity
MIMi194628 gene
neXtProtiNX_P58317
OpenTargetsiENSG00000197961
PharmGKBiPA37493

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000163151
HOGENOMiCLU_002678_44_0_1
InParanoidiP58317
OMAiQPNRITH
OrthoDBi1318335at2759
PhylomeDBiP58317
TreeFamiTF341966

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
7675 1 hit in 804 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF121 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
7675
PharosiP58317 Tdark

Protein Ontology

More...
PROi
PR:P58317
RNActiP58317 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000197961 Expressed in material anatomical entity and 200 other tissues
ExpressionAtlasiP58317 baseline and differential
GenevisibleiP58317 HS

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 9 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 9 hits
SUPFAMiSSF57667 SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 9 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN121_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P58317
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: July 10, 2007
Last modified: June 17, 2020
This is version 151 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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