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Protein

28S ribosomal protein S6, mitochondrial

Gene

Mrps6

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • small ribosomal subunit rRNA binding Source: GO_Central
  • structural constituent of ribosome Source: UniProtKB

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S6, mitochondrial
Short name:
MRP-S6
Short name:
S6mt
Gene namesi
Name:Mrps6
Synonyms:Rpms6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2153111 Mrps6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001768931 – 12528S ribosomal protein S6, mitochondrialAdd BLAST125

Proteomic databases

EPDiP58064
PaxDbiP58064
PeptideAtlasiP58064
PRIDEiP58064

PTM databases

iPTMnetiP58064
PhosphoSitePlusiP58064

Expressioni

Gene expression databases

BgeeiENSMUSG00000039680 Expressed in 274 organ(s), highest expression level in vestibular membrane of cochlear duct
ExpressionAtlasiP58064 baseline and differential
GenevisibleiP58064 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037631

Structurei

3D structure databases

ProteinModelPortaliP58064
SMRiP58064
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4708 Eukaryota
COG0360 LUCA
GeneTreeiENSGT00390000014606
HOGENOMiHOG000045806
HOVERGENiHBG082699
InParanoidiP58064
KOiK02990
OMAiPKSYPIA
OrthoDBiEOG091G0W0U
PhylomeDBiP58064
TreeFamiTF314045

Family and domain databases

Gene3Di3.30.70.60, 1 hit
InterProiView protein in InterPro
IPR000529 Ribosomal_S6
IPR035980 Ribosomal_S6_sf
IPR014717 Transl_elong_EF1B/ribosomal_S6
PANTHERiPTHR21011 PTHR21011, 1 hit
PfamiView protein in Pfam
PF01250 Ribosomal_S6, 1 hit
SUPFAMiSSF54995 SSF54995, 1 hit
TIGRFAMsiTIGR00166 S6, 1 hit

Sequencei

Sequence statusi: Complete.

P58064-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRYELALIL KAMRRPETAA ALKRTIESLM DRGAIVRNLE SLGERALPYR
60 70 80 90 100
ISSHSQQHSR GGYFLVDFYA PTSAVENILE HLARDIDVVR PNIVKHPLTQ
110 120
EVKECDGIVP VPLEEKLYST KRRKK
Length:125
Mass (Da):14,309
Last modified:January 23, 2007 - v3
Checksum:i8140DB0DBFDD9025
GO

Sequence cautioni

The sequence BAB40996 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049943 mRNA Translation: BAB40996.1 Different initiation.
AY061856 mRNA Translation: AAL35740.1
BC027271 mRNA Translation: AAH27271.1
CCDSiCCDS28332.1
RefSeqiNP_536704.1, NM_080456.1
UniGeneiMm.217354

Genome annotation databases

EnsembliENSMUST00000047429; ENSMUSP00000037631; ENSMUSG00000039680
GeneIDi121022
KEGGimmu:121022
UCSCiuc007zyu.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049943 mRNA Translation: BAB40996.1 Different initiation.
AY061856 mRNA Translation: AAL35740.1
BC027271 mRNA Translation: AAH27271.1
CCDSiCCDS28332.1
RefSeqiNP_536704.1, NM_080456.1
UniGeneiMm.217354

3D structure databases

ProteinModelPortaliP58064
SMRiP58064
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037631

PTM databases

iPTMnetiP58064
PhosphoSitePlusiP58064

Proteomic databases

EPDiP58064
PaxDbiP58064
PeptideAtlasiP58064
PRIDEiP58064

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000047429; ENSMUSP00000037631; ENSMUSG00000039680
GeneIDi121022
KEGGimmu:121022
UCSCiuc007zyu.1 mouse

Organism-specific databases

CTDi64968
MGIiMGI:2153111 Mrps6

Phylogenomic databases

eggNOGiKOG4708 Eukaryota
COG0360 LUCA
GeneTreeiENSGT00390000014606
HOGENOMiHOG000045806
HOVERGENiHBG082699
InParanoidiP58064
KOiK02990
OMAiPKSYPIA
OrthoDBiEOG091G0W0U
PhylomeDBiP58064
TreeFamiTF314045

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

PROiPR:P58064
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000039680 Expressed in 274 organ(s), highest expression level in vestibular membrane of cochlear duct
ExpressionAtlasiP58064 baseline and differential
GenevisibleiP58064 MM

Family and domain databases

Gene3Di3.30.70.60, 1 hit
InterProiView protein in InterPro
IPR000529 Ribosomal_S6
IPR035980 Ribosomal_S6_sf
IPR014717 Transl_elong_EF1B/ribosomal_S6
PANTHERiPTHR21011 PTHR21011, 1 hit
PfamiView protein in Pfam
PF01250 Ribosomal_S6, 1 hit
SUPFAMiSSF54995 SSF54995, 1 hit
TIGRFAMsiTIGR00166 S6, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRT06_MOUSE
AccessioniPrimary (citable) accession number: P58064
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: January 23, 2007
Last modified: September 12, 2018
This is version 129 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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