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Protein

Putative phosphotransferase enzyme IIB component SgcB

Gene

sgcB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei8Phosphocysteine intermediateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processPhosphotransferase system, Sugar transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-2121
MetaCyc:MONOMER0-2121

Protein family/group databases

TCDBi4.A.5.1.3 the pts galactitol (gat) family

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phosphotransferase enzyme IIB component SgcB (EC:2.7.1.-)
Alternative name(s):
Putative PTS system EIIB component
Gene namesi
Name:sgcB
Ordered Locus Names:b4565, JW5967
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14343 sgcB

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001866901 – 92Putative phosphotransferase enzyme IIB component SgcBAdd BLAST92

Proteomic databases

PaxDbiP58035
PRIDEiP58035

Interactioni

Protein-protein interaction databases

BioGridi4262742, 7 interactors
STRINGi316385.ECDH10B_4506

Structurei

3D structure databases

ProteinModelPortaliP58035
SMRiP58035
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 92PTS EIIB type-2PROSITE-ProRule annotationAdd BLAST92

Domaini

The EIIB domain is phosphorylated by phospho-EIIA on a cysteinyl or histidyl residue, depending on the transported sugar. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the EIIC domain.

Phylogenomic databases

eggNOGiENOG4105K18 Bacteria
COG3414 LUCA
HOGENOMiHOG000230475
KOiK02774
OMAiQVSMDQT
PhylomeDBiP58035

Family and domain databases

InterProiView protein in InterPro
IPR036095 PTS_EIIB-like_sf
IPR013011 PTS_EIIB_2
IPR003501 PTS_EIIB_2/3
PfamiView protein in Pfam
PF02302 PTS_IIB, 1 hit
SUPFAMiSSF52794 SSF52794, 1 hit
PROSITEiView protein in PROSITE
PS51099 PTS_EIIB_TYPE_2, 1 hit

Sequencei

Sequence statusi: Complete.

P58035-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKILVACGT GMSTSTMIAH KLQEFLTEQG ISATTAQCCL NEIPLNCNGM
60 70 80 90
DLIVTSMRTN SDYGIPTLNG AALLTGINDD ALKQQIKALL TQ
Length:92
Mass (Da):9,803
Last modified:April 27, 2001 - v1
Checksum:i371BC568AF1F0862
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: ABD18717.1
AP009048 Genomic DNA Translation: BAE78296.1
RefSeqiWP_000722973.1, NZ_LN832404.1
YP_588476.1, NC_000913.3

Genome annotation databases

EnsemblBacteriaiABD18717; ABD18717; b4565
BAE78296; BAE78296; BAE78296
GeneIDi1450295
KEGGiecj:JW5967
eco:b4565
PATRICifig|1411691.4.peg.2392

Entry informationi

Entry nameiSGCB_ECOLI
AccessioniPrimary (citable) accession number: P58035
Secondary accession number(s): Q2EEU3, Q2M610
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: March 28, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

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