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Entry version 162 (07 Apr 2021)
Sequence version 1 (11 Jan 2001)
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Protein

Poly(rC)-binding protein 4

Gene

PCBP4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Ribonucleoprotein, RNA-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
P57723

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6804116, TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
R-HSA-69895, Transcriptional activation of cell cycle inhibitor p21
R-HSA-9617828, FOXO-mediated transcription of cell cycle genes

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
P57723

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Poly(rC)-binding protein 4
Alternative name(s):
Alpha-CP4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PCBP4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:8652, PCBP4

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
608503, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P57723

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000090097.20

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
57060

Open Targets

More...
OpenTargetsi
ENSG00000090097

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA32991

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P57723, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PCBP4

Domain mapping of disease mutations (DMDM)

More...
DMDMi
12230429

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000500941 – 403Poly(rC)-binding protein 4Add BLAST403

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P57723

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P57723

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P57723

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P57723

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P57723

PeptideAtlas

More...
PeptideAtlasi
P57723

PRoteomics IDEntifications database

More...
PRIDEi
P57723

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
57014 [P57723-1]
57015 [P57723-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P57723

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P57723

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000090097, Expressed in right hemisphere of cerebellum and 232 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P57723, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P57723, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000090097, Tissue enhanced (skeletal)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
121351, 19 interactors

Protein interaction database and analysis system

More...
IntActi
P57723, 10 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000417196

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P57723, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P57723

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini17 – 67KH 1PROSITE-ProRule annotationAdd BLAST51
Domaini101 – 154KH 2PROSITE-ProRule annotationAdd BLAST54
Domaini241 – 293KH 3PROSITE-ProRule annotationAdd BLAST53

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2190, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159711

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_022670_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P57723

Identification of Orthologs from Complete Genome Data

More...
OMAi
HVLGTPY

Database of Orthologous Groups

More...
OrthoDBi
954970at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P57723

TreeFam database of animal gene trees

More...
TreeFami
TF318292

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1370.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004087, KH_dom
IPR004088, KH_dom_type_1
IPR036612, KH_dom_type_1_sf
IPR033088, PCBP4

The PANTHER Classification System

More...
PANTHERi
PTHR10288:SF166, PTHR10288:SF166, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00013, KH_1, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00322, KH, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54791, SSF54791, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50084, KH_TYPE_1, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 9 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P57723-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSGSDGGLEE EPELSITLTL RMLMHGKEVG SIIGKKGETV KRIREQSSAR
60 70 80 90 100
ITISEGSCPE RITTITGSTA AVFHAVSMIA FKLDEDLCAA PANGGNVSRP
110 120 130 140 150
PVTLRLVIPA SQCGSLIGKA GTKIKEIRET TGAQVQVAGD LLPNSTERAV
160 170 180 190 200
TVSGVPDAII LCVRQICAVI LESPPKGATI PYHPSLSLGT VLLSANQGFS
210 220 230 240 250
VQGQYGAVTP AEVTKLQQLS SHAVPFATPS VVPGLDPGTQ TSSQEFLVPN
260 270 280 290 300
DLIGCVIGRQ GSKISEIRQM SGAHIKIGNQ AEGAGERHVT ITGSPVSIAL
310 320 330 340 350
AQYLITACLE TAKSTSGGTP SSAPADLPAP FSPPLTALPT APPGLLGTPY
360 370 380 390 400
AISLSNFIGL KPMPFLALPP ASPGPPPGLA AYTAKMAAAN GSKKAERQKF

SPY
Length:403
Mass (Da):41,482
Last modified:January 11, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3D99F762A9471265
GO
Isoform 2 (identifier: P57723-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     130-172: Missing.

Show »
Length:360
Mass (Da):37,078
Checksum:i97B90BEC8EB3139A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9J0A4C9J0A4_HUMAN
Poly(rC)-binding protein 4
PCBP4
323Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J7A9C9J7A9_HUMAN
Poly(rC)-binding protein 4
PCBP4
86Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JSA6C9JSA6_HUMAN
Poly(rC)-binding protein 4
PCBP4
91Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JZY3C9JZY3_HUMAN
Poly(rC)-binding protein 4
PCBP4
168Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9IZV9C9IZV9_HUMAN
Poly(rC)-binding protein 4
PCBP4
74Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JTY5C9JTY5_HUMAN
Poly(rC)-binding protein 4
PCBP4
124Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WC71F8WC71_HUMAN
Poly(rC)-binding protein 4
PCBP4
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J5V4C9J5V4_HUMAN
Poly(rC)-binding protein 4
PCBP4
106Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9K0A2C9K0A2_HUMAN
Poly(rC)-binding protein 4
PCBP4
46Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_049681198G → S. Corresponds to variant dbSNP:rs323872Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_010016130 – 172Missing in isoform 2. 1 PublicationAdd BLAST43

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF176330 mRNA Translation: AAG09241.1
AK023993 mRNA Translation: BAB14761.1
BC003008 mRNA Translation: AAH03008.1
BC004153 mRNA Translation: AAH04153.1
BC017098 mRNA Translation: AAH17098.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2839.1 [P57723-1]
CCDS2840.2 [P57723-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001167571.1, NM_001174100.1 [P57723-1]
NP_065151.2, NM_020418.3 [P57723-2]
NP_127501.1, NM_033008.2 [P57723-1]
NP_127503.1, NM_033010.2 [P57723-1]
XP_005265388.1, XM_005265331.2 [P57723-1]
XP_006713331.1, XM_006713268.2
XP_006713332.1, XM_006713269.1 [P57723-1]
XP_006713333.1, XM_006713270.1 [P57723-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000322099; ENSP00000322341; ENSG00000090097 [P57723-1]
ENST00000355852; ENSP00000348111; ENSG00000090097 [P57723-1]
ENST00000428823; ENSP00000395030; ENSG00000090097 [P57723-2]
ENST00000461554; ENSP00000417196; ENSG00000090097 [P57723-1]
ENST00000484633; ENSP00000417100; ENSG00000090097 [P57723-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57060

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57060

UCSC genome browser

More...
UCSCi
uc003dcf.3, human [P57723-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF176330 mRNA Translation: AAG09241.1
AK023993 mRNA Translation: BAB14761.1
BC003008 mRNA Translation: AAH03008.1
BC004153 mRNA Translation: AAH04153.1
BC017098 mRNA Translation: AAH17098.1
CCDSiCCDS2839.1 [P57723-1]
CCDS2840.2 [P57723-2]
RefSeqiNP_001167571.1, NM_001174100.1 [P57723-1]
NP_065151.2, NM_020418.3 [P57723-2]
NP_127501.1, NM_033008.2 [P57723-1]
NP_127503.1, NM_033010.2 [P57723-1]
XP_005265388.1, XM_005265331.2 [P57723-1]
XP_006713331.1, XM_006713268.2
XP_006713332.1, XM_006713269.1 [P57723-1]
XP_006713333.1, XM_006713270.1 [P57723-2]

3D structure databases

SMRiP57723
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi121351, 19 interactors
IntActiP57723, 10 interactors
STRINGi9606.ENSP00000417196

PTM databases

iPTMnetiP57723
PhosphoSitePlusiP57723

Genetic variation databases

BioMutaiPCBP4
DMDMi12230429

Proteomic databases

EPDiP57723
jPOSTiP57723
MassIVEiP57723
MaxQBiP57723
PaxDbiP57723
PeptideAtlasiP57723
PRIDEiP57723
ProteomicsDBi57014 [P57723-1]
57015 [P57723-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
14226, 179 antibodies

Genome annotation databases

EnsembliENST00000322099; ENSP00000322341; ENSG00000090097 [P57723-1]
ENST00000355852; ENSP00000348111; ENSG00000090097 [P57723-1]
ENST00000428823; ENSP00000395030; ENSG00000090097 [P57723-2]
ENST00000461554; ENSP00000417196; ENSG00000090097 [P57723-1]
ENST00000484633; ENSP00000417100; ENSG00000090097 [P57723-2]
GeneIDi57060
KEGGihsa:57060
UCSCiuc003dcf.3, human [P57723-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57060
DisGeNETi57060

GeneCards: human genes, protein and diseases

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GeneCardsi
PCBP4
HGNCiHGNC:8652, PCBP4
HPAiENSG00000090097, Tissue enhanced (skeletal)
MIMi608503, gene
neXtProtiNX_P57723
OpenTargetsiENSG00000090097
PharmGKBiPA32991
VEuPathDBiHostDB:ENSG00000090097.20

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG2190, Eukaryota
GeneTreeiENSGT00940000159711
HOGENOMiCLU_022670_0_0_1
InParanoidiP57723
OMAiHVLGTPY
OrthoDBi954970at2759
PhylomeDBiP57723
TreeFamiTF318292

Enzyme and pathway databases

PathwayCommonsiP57723
ReactomeiR-HSA-6804116, TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
R-HSA-69895, Transcriptional activation of cell cycle inhibitor p21
R-HSA-9617828, FOXO-mediated transcription of cell cycle genes
SignaLinkiP57723

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
57060, 4 hits in 994 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
PCBP4, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
PCBP4

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
57060
PharosiP57723, Tbio

Protein Ontology

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PROi
PR:P57723
RNActiP57723, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000090097, Expressed in right hemisphere of cerebellum and 232 other tissues
ExpressionAtlasiP57723, baseline and differential
GenevisibleiP57723, HS

Family and domain databases

Gene3Di3.30.1370.10, 3 hits
InterProiView protein in InterPro
IPR004087, KH_dom
IPR004088, KH_dom_type_1
IPR036612, KH_dom_type_1_sf
IPR033088, PCBP4
PANTHERiPTHR10288:SF166, PTHR10288:SF166, 1 hit
PfamiView protein in Pfam
PF00013, KH_1, 3 hits
SMARTiView protein in SMART
SM00322, KH, 3 hits
SUPFAMiSSF54791, SSF54791, 3 hits
PROSITEiView protein in PROSITE
PS50084, KH_TYPE_1, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPCBP4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P57723
Secondary accession number(s): Q96AH7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: January 11, 2001
Last modified: April 7, 2021
This is version 162 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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