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Protein

Membrane-bound lytic murein transglycosylase A homolog

Gene

mltA

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity).By similarity

Catalytic activityi

Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCell wall biogenesis/degradation

Protein family/group databases

CAZyiGH102 Glycoside Hydrolase Family 102

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane-bound lytic murein transglycosylase A homolog (EC:4.2.2.n1)
Alternative name(s):
Murein hydrolase A
Gene namesi
Name:mltA
Ordered Locus Names:BU458
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000001806 Componenti: Chromosome

Subcellular locationi

    Note: In closely related bacteria this protein is attached to the outer membrane by a lipid anchor. This is apparently not the case here.

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001965661 – 359Membrane-bound lytic murein transglycosylase A homologAdd BLAST359

Interactioni

Protein-protein interaction databases

STRINGi107806.BU458

Structurei

3D structure databases

ProteinModelPortaliP57531
SMRiP57531
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105CA3 Bacteria
COG2821 LUCA
HOGENOMiHOG000278098
KOiK08304
OMAiDQNGHPY

Family and domain databases

CDDicd14485 mltA_like_LT_A, 1 hit
Gene3Di2.40.40.10, 2 hits
InterProiView protein in InterPro
IPR010611 3D_dom
IPR026044 MltA
IPR034654 MltA_3D
IPR005300 MltA_B
IPR036908 RlpA-like_sf
PANTHERiPTHR30124 PTHR30124, 1 hit
PfamiView protein in Pfam
PF06725 3D, 1 hit
PF03562 MltA, 1 hit
PIRSFiPIRSF019422 MltA, 1 hit
SMARTiView protein in SMART
SM00925 MltA, 1 hit
SUPFAMiSSF50685 SSF50685, 1 hit

Sequencei

Sequence statusi: Complete.

P57531-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQKKIIKTII FFSLFFLFEK SYAYININQG QQYEKKLIQN LTKIKQINIK
60 70 80 90 100
KKIINAESFY IQVEKIKKFS PSLYLKNEST YKTILKWLKK NSNINELNEF
110 120 130 140 150
GINLFQMKGI DNYGNVKITG YYTPIVQARK IKKNNFKYPI YSMPYHLKKN
160 170 180 190 200
EPLPKRKDIY NGVLDKKYIL AYSNSLIDNF IMEIQGSAFI DYGNKKKLIF
210 220 230 240 250
FSYAGKNGWP YKSIGQILIN RGDIEKKNMS MQAINKWFTK HTNKEIQDLF
260 270 280 290 300
EKNESFVFFK ETKKKQVYGA SAVPLIAQTS VAADNSIIKK GSVILLKIPI
310 320 330 340 350
LDQNGVFLNK YEMRLVIALD VGGAIKGHHF DIYEGIGTKA SILSGYYNHY

GYAWILNKK
Length:359
Mass (Da):41,773
Last modified:March 1, 2001 - v1
Checksum:i24E12A2778D351AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA Translation: BAB13155.1
RefSeqiNP_240269.1, NC_002528.1
WP_009874410.1, NC_002528.1

Genome annotation databases

EnsemblBacteriaiBAB13155; BAB13155; BAB13155
GeneIDi1109805
KEGGibuc:BU458
PATRICifig|107806.10.peg.467

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA Translation: BAB13155.1
RefSeqiNP_240269.1, NC_002528.1
WP_009874410.1, NC_002528.1

3D structure databases

ProteinModelPortaliP57531
SMRiP57531
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi107806.BU458

Protein family/group databases

CAZyiGH102 Glycoside Hydrolase Family 102

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB13155; BAB13155; BAB13155
GeneIDi1109805
KEGGibuc:BU458
PATRICifig|107806.10.peg.467

Phylogenomic databases

eggNOGiENOG4105CA3 Bacteria
COG2821 LUCA
HOGENOMiHOG000278098
KOiK08304
OMAiDQNGHPY

Family and domain databases

CDDicd14485 mltA_like_LT_A, 1 hit
Gene3Di2.40.40.10, 2 hits
InterProiView protein in InterPro
IPR010611 3D_dom
IPR026044 MltA
IPR034654 MltA_3D
IPR005300 MltA_B
IPR036908 RlpA-like_sf
PANTHERiPTHR30124 PTHR30124, 1 hit
PfamiView protein in Pfam
PF06725 3D, 1 hit
PF03562 MltA, 1 hit
PIRSFiPIRSF019422 MltA, 1 hit
SMARTiView protein in SMART
SM00925 MltA, 1 hit
SUPFAMiSSF50685 SSF50685, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMLTA_BUCAI
AccessioniPrimary (citable) accession number: P57531
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: March 1, 2001
Last modified: February 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
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