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Protein

ATP-dependent RNA helicase DeaD

Gene

deaD

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi50 – 57ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicase, Hydrolase, RNA-binding
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent RNA helicase DeaDUniRule annotation (EC:3.6.4.13UniRule annotation)
Alternative name(s):
Cold-shock DEAD box protein AUniRule annotation
Gene namesi
Name:deaDUniRule annotation
Synonyms:csdA
Ordered Locus Names:BU372
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000001806 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000550981 – 601ATP-dependent RNA helicase DeaDAdd BLAST601

Proteomic databases

PRIDEiP57453

Interactioni

Protein-protein interaction databases

STRINGi107806.BU372

Structurei

3D structure databases

ProteinModelPortaliP57453
SMRiP57453
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 208Helicase ATP-bindingUniRule annotationAdd BLAST172
Domaini231 – 378Helicase C-terminalUniRule annotationAdd BLAST148

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi6 – 34Q motifAdd BLAST29
Motifi156 – 159DEAD box4

Sequence similaritiesi

Belongs to the DEAD box helicase family. DeaD subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1J Bacteria
COG0513 LUCA
HOGENOMiHOG000268810
KOiK05592
OMAiLPQGMPK

Family and domain databases

CDDicd00079 HELICc, 1 hit
cd12499 RRM_EcCsdA_like, 1 hit
Gene3Di3.30.70.330, 1 hit
HAMAPiMF_00964 DEAD_helicase_DeaD, 1 hit
InterProiView protein in InterPro
IPR034415 CsdA_RRM
IPR005580 DbpA/CsdA_RNA-bd_dom
IPR011545 DEAD/DEAH_box_helicase_dom
IPR028618 DEAD_helicase_DeaD
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF03880 DbpA, 1 hit
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit

Sequencei

Sequence statusi: Complete.

P57453-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTHIESTFSF LGLNPFIIQS LNEMGYVKPS PIQASCIPLL LEGRDVLGMA
60 70 80 90 100
QTGSGKTAAF SLPLLHNLNI NLKAPQILVL APTRELAVQV AEAFSDFSKY
110 120 130 140 150
MIGIHVLPLY GGQRYELQLR ALRQGPQIVV GTPGRLLDHL KRGTLNLSNL
160 170 180 190 200
HGLVLDEADE MLRMGFIEDV ETIMAQIPKE HQTALFSATM PEAIRRISKR
210 220 230 240 250
FMRNPKEIKI QSNITTRPDI KQSYWMVYGR KTDALIRFLE AEDFSATIIF
260 270 280 290 300
VRTKNATLEV SEALERNGYN SAALNGDMNQ ALREQTLERL KNGRLDILIA
310 320 330 340 350
TDVAARGLDV DRISFVINYD IPMDSESYVH RIGRTGRAGR AGRALLFVEN
360 370 380 390 400
RERRLLRNIE RTMKQSIPEV QLPKVELLCQ RRLEQFAKKV QQQLESRDLD
410 420 430 440 450
EYSALLDKLY STDDLDIKTL AAALLKMAQG ERPLIIKPDV IKRQSRDLLF
460 470 480 490 500
QDDRRREDNR NSRTRRDRRD INKDAELYRI EVGRNDGVEV RHIVGAIANE
510 520 530 540 550
GNINSRNIGN IKLFSSYSTI ELPKGMSKDL LQTFNRTRIL NKPINMKLLR
560 570 580 590 600
DSRHYENKTT HRSIFNKDKN SNRRVSDGSF NKSNSPKKTE FKSSFFRRRN

V
Length:601
Mass (Da):68,806
Last modified:December 1, 2000 - v1
Checksum:i886C237AC5E61279
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA Translation: BAB13076.1
RefSeqiNP_240190.1, NC_002528.1
WP_009874330.1, NC_002528.1

Genome annotation databases

EnsemblBacteriaiBAB13076; BAB13076; BAB13076
GeneIDi1109726
KEGGibuc:BU372
PATRICifig|107806.10.peg.386

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000003 Genomic DNA Translation: BAB13076.1
RefSeqiNP_240190.1, NC_002528.1
WP_009874330.1, NC_002528.1

3D structure databases

ProteinModelPortaliP57453
SMRiP57453
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi107806.BU372

Proteomic databases

PRIDEiP57453

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB13076; BAB13076; BAB13076
GeneIDi1109726
KEGGibuc:BU372
PATRICifig|107806.10.peg.386

Phylogenomic databases

eggNOGiENOG4105C1J Bacteria
COG0513 LUCA
HOGENOMiHOG000268810
KOiK05592
OMAiLPQGMPK

Family and domain databases

CDDicd00079 HELICc, 1 hit
cd12499 RRM_EcCsdA_like, 1 hit
Gene3Di3.30.70.330, 1 hit
HAMAPiMF_00964 DEAD_helicase_DeaD, 1 hit
InterProiView protein in InterPro
IPR034415 CsdA_RRM
IPR005580 DbpA/CsdA_RNA-bd_dom
IPR011545 DEAD/DEAH_box_helicase_dom
IPR028618 DEAD_helicase_DeaD
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF03880 DbpA, 1 hit
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiDEAD_BUCAI
AccessioniPrimary (citable) accession number: P57453
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: October 10, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
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Main funding by: National Institutes of Health

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