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UniProtKB - P57086 (SCND1_HUMAN)
Protein
SCAN domain-containing protein 1
Gene
SCAND1
Organism
Homo sapiens (Human)
Status
Functioni
May regulate transcriptional activity.
GO - Biological processi
- positive regulation of transcription, DNA-templated Source: Ensembl
Enzyme and pathway databases
PathwayCommonsi | P57086 |
SignaLinki | P57086 |
SIGNORi | P57086 |
Protein family/group databases
MoonDBi | P57086, Predicted |
Names & Taxonomyi
Protein namesi | Recommended name: SCAN domain-containing protein 1 |
Gene namesi | Name:SCAND1 Synonyms:SDP1 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:10566, SCAND1 |
MIMi | 610416, gene |
neXtProti | NX_P57086 |
VEuPathDBi | HostDB:ENSG00000171222 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Nucleus
- nucleus Source: LIFEdb
Keywords - Cellular componenti
NucleusPathology & Biotechi
Organism-specific databases
DisGeNETi | 51282 |
OpenTargetsi | ENSG00000171222 |
PharmGKBi | PA34979 |
Miscellaneous databases
Pharosi | P57086, Tbio |
Genetic variation databases
BioMutai | SCAND1 |
DMDMi | 10720272 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000097632 | 1 – 179 | SCAN domain-containing protein 1Add BLAST | 179 |
Proteomic databases
EPDi | P57086 |
jPOSTi | P57086 |
MassIVEi | P57086 |
MaxQBi | P57086 |
PaxDbi | P57086 |
PeptideAtlasi | P57086 |
PRIDEi | P57086 |
ProteomicsDBi | 56995 |
PTM databases
iPTMneti | P57086 |
PhosphoSitePlusi | P57086 |
Expressioni
Gene expression databases
Bgeei | ENSG00000171222, Expressed in prostate gland and 226 other tissues |
Genevisiblei | P57086, HS |
Organism-specific databases
HPAi | ENSG00000171222, Low tissue specificity |
Interactioni
Subunit structurei
Interacts with ZNF202.
Binary interactionsi
P57086
Protein-protein interaction databases
BioGRIDi | 119434, 63 interactors |
IntActi | P57086, 57 interactors |
MINTi | P57086 |
STRINGi | 9606.ENSP00000363103 |
Miscellaneous databases
RNActi | P57086, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 108 – 166 | SCAN boxPROSITE-ProRule annotationAdd BLAST | 59 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 104 | DisorderedSequence analysisAdd BLAST | 104 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 43 – 57 | Pro residuesSequence analysisAdd BLAST | 15 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000163024 |
HOGENOMi | CLU_107409_0_0_1 |
InParanoidi | P57086 |
OMAi | QALRWCR |
PhylomeDBi | P57086 |
Family and domain databases
CDDi | cd07936, SCAN, 1 hit |
Gene3Di | 1.10.4020.10, 1 hit |
InterProi | View protein in InterPro IPR003309, SCAN_dom IPR038269, SCAN_sf |
Pfami | View protein in Pfam PF02023, SCAN, 1 hit |
SMARTi | View protein in SMART SM00431, SCAN, 1 hit |
PROSITEi | View protein in PROSITE PS50804, SCAN_BOX, 1 hit |
i Sequence
Sequence statusi: Complete.
P57086-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAATEPILAA TGSPAAVPPE KLEGAGSSSA PERNCVGSSL PEASPPAPEP
60 70 80 90 100
SSPNAAVPEA IPTPRAAASA ALELPLGPAP VSVAPQAEAE ARSTPGPAGS
110 120 130 140 150
RLGPETFRQR FRQFRYQDAA GPREAFRQLR ELSRQWLRPD IRTKEQIVEM
160 170
LVQEQLLAIL PEAARARRIR RRTDVRITG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF204271 mRNA Translation: AAF59839.1 CR457188 mRNA Translation: CAG33469.1 AL109965 Genomic DNA No translation available. CH471077 Genomic DNA Translation: EAW76150.1 BC000785 mRNA Translation: AAH00785.1 BC036709 mRNA Translation: AAH36709.1 BC041022 mRNA Translation: AAH41022.1 |
CCDSi | CCDS13269.1 |
RefSeqi | NP_057642.1, NM_016558.3 NP_361012.2, NM_033630.2 |
Genome annotation databases
Ensembli | ENST00000305978; ENSP00000301995; ENSG00000171222 ENST00000373991; ENSP00000363103; ENSG00000171222 ENST00000615116; ENSP00000481289; ENSG00000171222 |
GeneIDi | 51282 |
KEGGi | hsa:51282 |
MANE-Selecti | ENST00000305978.7; ENSP00000301995.2; NM_033630.3; NP_361012.3 |
UCSCi | uc002xen.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF204271 mRNA Translation: AAF59839.1 CR457188 mRNA Translation: CAG33469.1 AL109965 Genomic DNA No translation available. CH471077 Genomic DNA Translation: EAW76150.1 BC000785 mRNA Translation: AAH00785.1 BC036709 mRNA Translation: AAH36709.1 BC041022 mRNA Translation: AAH41022.1 |
CCDSi | CCDS13269.1 |
RefSeqi | NP_057642.1, NM_016558.3 NP_361012.2, NM_033630.2 |
3D structure databases
SMRi | P57086 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 119434, 63 interactors |
IntActi | P57086, 57 interactors |
MINTi | P57086 |
STRINGi | 9606.ENSP00000363103 |
Protein family/group databases
MoonDBi | P57086, Predicted |
PTM databases
iPTMneti | P57086 |
PhosphoSitePlusi | P57086 |
Genetic variation databases
BioMutai | SCAND1 |
DMDMi | 10720272 |
Proteomic databases
EPDi | P57086 |
jPOSTi | P57086 |
MassIVEi | P57086 |
MaxQBi | P57086 |
PaxDbi | P57086 |
PeptideAtlasi | P57086 |
PRIDEi | P57086 |
ProteomicsDBi | 56995 |
Protocols and materials databases
Antibodypediai | 11616, 232 antibodies from 27 providers |
DNASUi | 51282 |
Genome annotation databases
Ensembli | ENST00000305978; ENSP00000301995; ENSG00000171222 ENST00000373991; ENSP00000363103; ENSG00000171222 ENST00000615116; ENSP00000481289; ENSG00000171222 |
GeneIDi | 51282 |
KEGGi | hsa:51282 |
MANE-Selecti | ENST00000305978.7; ENSP00000301995.2; NM_033630.3; NP_361012.3 |
UCSCi | uc002xen.3, human |
Organism-specific databases
CTDi | 51282 |
DisGeNETi | 51282 |
GeneCardsi | SCAND1 |
HGNCi | HGNC:10566, SCAND1 |
HPAi | ENSG00000171222, Low tissue specificity |
MIMi | 610416, gene |
neXtProti | NX_P57086 |
OpenTargetsi | ENSG00000171222 |
PharmGKBi | PA34979 |
VEuPathDBi | HostDB:ENSG00000171222 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000163024 |
HOGENOMi | CLU_107409_0_0_1 |
InParanoidi | P57086 |
OMAi | QALRWCR |
PhylomeDBi | P57086 |
Enzyme and pathway databases
PathwayCommonsi | P57086 |
SignaLinki | P57086 |
SIGNORi | P57086 |
Miscellaneous databases
BioGRID-ORCSi | 51282, 28 hits in 1048 CRISPR screens |
ChiTaRSi | SCAND1, human |
GeneWikii | SCAND1 |
GenomeRNAii | 51282 |
Pharosi | P57086, Tbio |
PROi | PR:P57086 |
RNActi | P57086, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000171222, Expressed in prostate gland and 226 other tissues |
Genevisiblei | P57086, HS |
Family and domain databases
CDDi | cd07936, SCAN, 1 hit |
Gene3Di | 1.10.4020.10, 1 hit |
InterProi | View protein in InterPro IPR003309, SCAN_dom IPR038269, SCAN_sf |
Pfami | View protein in Pfam PF02023, SCAN, 1 hit |
SMARTi | View protein in SMART SM00431, SCAN, 1 hit |
PROSITEi | View protein in PROSITE PS50804, SCAN_BOX, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SCND1_HUMAN | |
Accessioni | P57086Primary (citable) accession number: P57086 Secondary accession number(s): Q6IAG7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 1, 2000 |
Last sequence update: | December 1, 2000 | |
Last modified: | February 23, 2022 | |
This is version 168 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 20
Human chromosome 20: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot