SCAND1

Functionⁱ

May regulate transcriptional activity.

GO - Molecular functionⁱ

DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
DNA-binding transcription factor activity Source: UniProtKB
identical protein binding Source: UniProtKB
transcription coactivator activity Source: Ensembl

View the complete GO annotation on QuickGO ...

Enzyme and pathway databases

SIGNORⁱ	P57086

SIGNORⁱ

P57086

Protein family/group databases

MoonDBⁱ	P57086 Predicted

MoonDBⁱ

P57086 Predicted

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: SCAN domain-containing protein 1
Gene namesⁱ	Name:SCAND1 Synonyms:SDP1
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 20

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000171222.10
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:10566 SCAND1
MIMⁱ	610416 gene
neXtProtⁱ	NX_P57086

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000171222
PharmGKBⁱ	PA34979

Polymorphism and mutation databases

BioMutaⁱ	SCAND1
DMDMⁱ	10720272

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000097632	1 – 179	SCAN domain-containing protein 1Add BLAST		179

Proteomic databases

EPDⁱ	P57086
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P57086
PaxDbⁱ	P57086
PeptideAtlas More...PeptideAtlasⁱ	P57086
PRIDEⁱ	P57086
ProteomicsDBⁱ	56995

PTM databases

iPTMnetⁱ	P57086
PhosphoSitePlusⁱ	P57086

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000171222 Expressed in 213 organ(s), highest expression level in prostate gland
CleanExⁱ	HS_SCAND1
Genevisibleⁱ	P57086 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA047138

HPAⁱ

HPA047138

Interactionⁱ

Subunit structureⁱ

Interacts with ZNF202.

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
GORASP2	Q9H8Y8	5	EBI-745846,EBI-739467
PGBD1	Q96JS3	8	EBI-745846,EBI-10290053
PNMA1	Q8ND90	3	EBI-745846,EBI-302345
ZKSCAN3	Q9BRR0	4	EBI-745846,EBI-1965777
ZKSCAN4	Q969J2	5	EBI-745846,EBI-2818641
ZKSCAN7	Q9P0L1	4	EBI-745846,EBI-743851
ZKSCAN7	Q9P0L1-2	4	EBI-745846,EBI-10698225
ZNF165	P49910	5	EBI-745846,EBI-741694
ZNF24	P17028	5	EBI-745846,EBI-707773
ZNF263	O14978	3	EBI-745846,EBI-744493
ZNF449	Q6P9G9	5	EBI-745846,EBI-10215956

GO - Molecular functionⁱ

identical protein binding Source: UniProtKB

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	119434, 30 interactors
IntActⁱ	P57086, 50 interactors
Molecular INTeraction database More...MINTⁱ	P57086
STRINGⁱ	9606.ENSP00000301995

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P57086
SMRⁱ	P57086
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	108 – 166	SCAN boxPROSITE-ProRule annotationAdd BLAST		59

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00910000144000
HOVERGENⁱ	HBG079091
InParanoidⁱ	P57086
OMAⁱ	TGQRVTP
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G16SE
PhylomeDBⁱ	P57086

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd07936 SCAN, 1 hit
Gene3Dⁱ	1.10.4020.10, 1 hit
InterProⁱ	View protein in InterPro IPR003309 SCAN_dom IPR038269 SCAN_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02023 SCAN, 1 hit
SMARTⁱ	View protein in SMART SM00431 SCAN, 1 hit
PROSITEⁱ	View protein in PROSITE PS50804 SCAN_BOX, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P57086-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAATEPILAA TGSPAAVPPE KLEGAGSSSA PERNCVGSSL PEASPPAPEP 
        60         70         80         90        100
SSPNAAVPEA IPTPRAAASA ALELPLGPAP VSVAPQAEAE ARSTPGPAGS 
       110        120        130        140        150
RLGPETFRQR FRQFRYQDAA GPREAFRQLR ELSRQWLRPD IRTKEQIVEM 
       160        170 
LVQEQLLAIL PEAARARRIR RRTDVRITG

Length:179

Mass (Da):19,082

Last modified:December 1, 2000 - v1

Checksum:ⁱ88AFEFC8E4DC9796

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF204271 mRNA Translation: AAF59839.1 CR457188 mRNA Translation: CAG33469.1 AL109965 Genomic DNA No translation available. CH471077 Genomic DNA Translation: EAW76150.1 BC000785 mRNA Translation: AAH00785.1 BC036709 mRNA Translation: AAH36709.1 BC041022 mRNA Translation: AAH41022.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS13269.1
NCBI Reference Sequences More...RefSeqⁱ	NP_057642.1, NM_016558.3
UniGeneⁱ	Hs.584909

Genome annotation databases

Ensemblⁱ	ENST00000305978; ENSP00000301995; ENSG00000171222 ENST00000373991; ENSP00000363103; ENSG00000171222 ENST00000615116; ENSP00000481289; ENSG00000171222
GeneIDⁱ	51282
KEGGⁱ	hsa:51282
UCSC genome browser More...UCSCⁱ	uc002xen.3 human

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P57086	SCAN domain-containing protein 1		GORGO		179	UniRef100_P57086
SCAN domain containing 1, isoform CRA_b		HUMAN		242
SCAN-related protein RAZ1 (Fragment)		HUMAN		217

Protein	Similar proteins		Species	Score	Length	Source
P57086	SCAN domain-containing protein 1		GORGO		179	UniRef90_P57086
SCAN domain-containing protein 1		PANPA		179
SCAN domain-containing protein 1		PANTR		179
SCAN domain containing 1, isoform CRA_b		HUMAN		242
Uncharacterized protein		PONAB		242
+21

Protein	Similar proteins		Species	Score	Length	Source
P57086	SCAN domain-containing protein 1		GORGO		179	UniRef50_P57086
SCAN domain-containing protein 1		PANPA		179
SCAN domain-containing protein 1		PANTR		179
SCAN domain containing 1, isoform CRA_b		HUMAN		242
Uncharacterized protein		PONAB		242
+43

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF204271 mRNA Translation: AAF59839.1 CR457188 mRNA Translation: CAG33469.1 AL109965 Genomic DNA No translation available. CH471077 Genomic DNA Translation: EAW76150.1 BC000785 mRNA Translation: AAH00785.1 BC036709 mRNA Translation: AAH36709.1 BC041022 mRNA Translation: AAH41022.1
CCDSⁱ	CCDS13269.1
RefSeqⁱ	NP_057642.1, NM_016558.3
UniGeneⁱ	Hs.584909

3D structure databases

ProteinModelPortalⁱ	P57086
SMRⁱ	P57086
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	119434, 30 interactors
IntActⁱ	P57086, 50 interactors
MINTⁱ	P57086
STRINGⁱ	9606.ENSP00000301995

Protein family/group databases

MoonDBⁱ	P57086 Predicted

MoonDBⁱ

P57086 Predicted

PTM databases

iPTMnetⁱ	P57086
PhosphoSitePlusⁱ	P57086

Polymorphism and mutation databases

BioMutaⁱ	SCAND1
DMDMⁱ	10720272

Proteomic databases

EPDⁱ	P57086
MaxQBⁱ	P57086
PaxDbⁱ	P57086
PeptideAtlasⁱ	P57086
PRIDEⁱ	P57086
ProteomicsDBⁱ	56995

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	51282
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000305978; ENSP00000301995; ENSG00000171222 ENST00000373991; ENSP00000363103; ENSG00000171222 ENST00000615116; ENSP00000481289; ENSG00000171222
GeneIDⁱ	51282
KEGGⁱ	hsa:51282
UCSCⁱ	uc002xen.3 human

Organism-specific databases

CTDⁱ	51282
EuPathDBⁱ	HostDB:ENSG00000171222.10
GeneCardsⁱ	SCAND1
HGNCⁱ	HGNC:10566 SCAND1
HPAⁱ	HPA047138
MIMⁱ	610416 gene
neXtProtⁱ	NX_P57086
OpenTargetsⁱ	ENSG00000171222
PharmGKBⁱ	PA34979
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00910000144000
HOVERGENⁱ	HBG079091
InParanoidⁱ	P57086
OMAⁱ	TGQRVTP
OrthoDBⁱ	EOG091G16SE
PhylomeDBⁱ	P57086

Enzyme and pathway databases

SIGNORⁱ	P57086

SIGNORⁱ

P57086

Miscellaneous databases

ChiTaRSⁱ	SCAND1 human
GeneWikiⁱ	SCAND1
GenomeRNAiⁱ	51282
Protein Ontology More...PROⁱ	PR:P57086
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000171222 Expressed in 213 organ(s), highest expression level in prostate gland
CleanExⁱ	HS_SCAND1
Genevisibleⁱ	P57086 HS

Family and domain databases

CDDⁱ	cd07936 SCAN, 1 hit
Gene3Dⁱ	1.10.4020.10, 1 hit
InterProⁱ	View protein in InterPro IPR003309 SCAN_dom IPR038269 SCAN_sf
Pfamⁱ	View protein in Pfam PF02023 SCAN, 1 hit
SMARTⁱ	View protein in SMART SM00431 SCAN, 1 hit
PROSITEⁱ	View protein in PROSITE PS50804 SCAN_BOX, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SCND1_HUMAN
Accessionⁱ	P57086Primary (citable) accession number: P57086 Secondary accession number(s): Q6IAG7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
	Last sequence update:	December 1, 2000
	Last modified:	November 7, 2018
	This is version 149 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 20
Human chromosome 20: entries, gene names and cross-references to MIM

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P57086 (SCND1_HUMAN)

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SCAN domain-containing protein 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ