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Protein

SCAN domain-containing protein 1

Gene

SCAND1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May regulate transcriptional activity.

GO - Molecular functioni

Enzyme and pathway databases

SIGNORiP57086

Protein family/group databases

MoonDBiP57086 Predicted

Names & Taxonomyi

Protein namesi
Recommended name:
SCAN domain-containing protein 1
Gene namesi
Name:SCAND1
Synonyms:SDP1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000171222.10
HGNCiHGNC:10566 SCAND1
MIMi610416 gene
neXtProtiNX_P57086

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000171222
PharmGKBiPA34979

Polymorphism and mutation databases

BioMutaiSCAND1
DMDMi10720272

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000976321 – 179SCAN domain-containing protein 1Add BLAST179

Proteomic databases

EPDiP57086
MaxQBiP57086
PaxDbiP57086
PeptideAtlasiP57086
PRIDEiP57086
ProteomicsDBi56995

PTM databases

iPTMnetiP57086
PhosphoSitePlusiP57086

Expressioni

Gene expression databases

BgeeiENSG00000171222 Expressed in 213 organ(s), highest expression level in prostate gland
CleanExiHS_SCAND1
GenevisibleiP57086 HS

Organism-specific databases

HPAiHPA047138

Interactioni

Subunit structurei

Interacts with ZNF202.

Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

BioGridi119434, 30 interactors
IntActiP57086, 50 interactors
MINTiP57086
STRINGi9606.ENSP00000301995

Structurei

3D structure databases

ProteinModelPortaliP57086
SMRiP57086
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini108 – 166SCAN boxPROSITE-ProRule annotationAdd BLAST59

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00910000144000
HOVERGENiHBG079091
InParanoidiP57086
OMAiTGQRVTP
OrthoDBiEOG091G16SE
PhylomeDBiP57086

Family and domain databases

CDDicd07936 SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR003309 SCAN_dom
IPR038269 SCAN_sf
PfamiView protein in Pfam
PF02023 SCAN, 1 hit
SMARTiView protein in SMART
SM00431 SCAN, 1 hit
PROSITEiView protein in PROSITE
PS50804 SCAN_BOX, 1 hit

Sequencei

Sequence statusi: Complete.

P57086-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAATEPILAA TGSPAAVPPE KLEGAGSSSA PERNCVGSSL PEASPPAPEP
60 70 80 90 100
SSPNAAVPEA IPTPRAAASA ALELPLGPAP VSVAPQAEAE ARSTPGPAGS
110 120 130 140 150
RLGPETFRQR FRQFRYQDAA GPREAFRQLR ELSRQWLRPD IRTKEQIVEM
160 170
LVQEQLLAIL PEAARARRIR RRTDVRITG
Length:179
Mass (Da):19,082
Last modified:December 1, 2000 - v1
Checksum:i88AFEFC8E4DC9796
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF204271 mRNA Translation: AAF59839.1
CR457188 mRNA Translation: CAG33469.1
AL109965 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW76150.1
BC000785 mRNA Translation: AAH00785.1
BC036709 mRNA Translation: AAH36709.1
BC041022 mRNA Translation: AAH41022.1
CCDSiCCDS13269.1
RefSeqiNP_057642.1, NM_016558.3
UniGeneiHs.584909

Genome annotation databases

EnsembliENST00000305978; ENSP00000301995; ENSG00000171222
ENST00000373991; ENSP00000363103; ENSG00000171222
ENST00000615116; ENSP00000481289; ENSG00000171222
GeneIDi51282
KEGGihsa:51282
UCSCiuc002xen.3 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF204271 mRNA Translation: AAF59839.1
CR457188 mRNA Translation: CAG33469.1
AL109965 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW76150.1
BC000785 mRNA Translation: AAH00785.1
BC036709 mRNA Translation: AAH36709.1
BC041022 mRNA Translation: AAH41022.1
CCDSiCCDS13269.1
RefSeqiNP_057642.1, NM_016558.3
UniGeneiHs.584909

3D structure databases

ProteinModelPortaliP57086
SMRiP57086
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119434, 30 interactors
IntActiP57086, 50 interactors
MINTiP57086
STRINGi9606.ENSP00000301995

Protein family/group databases

MoonDBiP57086 Predicted

PTM databases

iPTMnetiP57086
PhosphoSitePlusiP57086

Polymorphism and mutation databases

BioMutaiSCAND1
DMDMi10720272

Proteomic databases

EPDiP57086
MaxQBiP57086
PaxDbiP57086
PeptideAtlasiP57086
PRIDEiP57086
ProteomicsDBi56995

Protocols and materials databases

DNASUi51282
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000305978; ENSP00000301995; ENSG00000171222
ENST00000373991; ENSP00000363103; ENSG00000171222
ENST00000615116; ENSP00000481289; ENSG00000171222
GeneIDi51282
KEGGihsa:51282
UCSCiuc002xen.3 human

Organism-specific databases

CTDi51282
EuPathDBiHostDB:ENSG00000171222.10
GeneCardsiSCAND1
HGNCiHGNC:10566 SCAND1
HPAiHPA047138
MIMi610416 gene
neXtProtiNX_P57086
OpenTargetsiENSG00000171222
PharmGKBiPA34979
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00910000144000
HOVERGENiHBG079091
InParanoidiP57086
OMAiTGQRVTP
OrthoDBiEOG091G16SE
PhylomeDBiP57086

Enzyme and pathway databases

SIGNORiP57086

Miscellaneous databases

ChiTaRSiSCAND1 human
GeneWikiiSCAND1
GenomeRNAii51282
PROiPR:P57086
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000171222 Expressed in 213 organ(s), highest expression level in prostate gland
CleanExiHS_SCAND1
GenevisibleiP57086 HS

Family and domain databases

CDDicd07936 SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR003309 SCAN_dom
IPR038269 SCAN_sf
PfamiView protein in Pfam
PF02023 SCAN, 1 hit
SMARTiView protein in SMART
SM00431 SCAN, 1 hit
PROSITEiView protein in PROSITE
PS50804 SCAN_BOX, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSCND1_HUMAN
AccessioniPrimary (citable) accession number: P57086
Secondary accession number(s): Q6IAG7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: November 7, 2018
This is version 149 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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