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UniProtKB - P57057 (G6PT2_HUMAN)

Entry version 153 (23 Feb 2022)
Sequence version 2 (11 Jan 2011)
Previous versions | rss
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Protein

Glucose-6-phosphate exchanger SLC37A1

Gene

SLC37A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by vanadate but not by chlorogenic acid.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAntiport, Sugar transport, Transport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P57057

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-70263, Gluconeogenesis

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		P57057

Protein family/group databases

Transport Classification Database

More...TCDBi		2.A.1.4.7, the major facilitator superfamily (mfs)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glucose-6-phosphate exchanger SLC37A11 Publication
Alternative name(s):
Glycerol-3-phosphate permease1 Publication
Short name:
G-3-P permease1 Publication
Solute carrier family 37 member 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC37A1Imported
Synonyms:G3PP1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:11024, SLC37A1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		608094, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P57057

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000160190

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei18 – 38HelicalSequence analysisAdd BLAST21
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Transmembranei129 – 149HelicalSequence analysisAdd BLAST21
Transmembranei157 – 177HelicalSequence analysisAdd BLAST21
Transmembranei222 – 242HelicalSequence analysisAdd BLAST21
Transmembranei304 – 324HelicalSequence analysisAdd BLAST21
Transmembranei334 – 354HelicalSequence analysisAdd BLAST21
Transmembranei366 – 386HelicalSequence analysisAdd BLAST21
Transmembranei394 – 414HelicalSequence analysisAdd BLAST21
Transmembranei423 – 443HelicalSequence analysisAdd BLAST21
Transmembranei466 – 486HelicalSequence analysisAdd BLAST21
Transmembranei490 – 510HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		54020

Open Targets

More...OpenTargetsi		ENSG00000160190

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA35892

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P57057, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SLC37A1

Domain mapping of disease mutations (DMDM)

More...DMDMi		317373359

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001998901 – 533Glucose-6-phosphate exchanger SLC37A1Add BLAST533

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi81N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi263N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P57057

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P57057

MaxQB - The MaxQuant DataBase

More...MaxQBi		P57057

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P57057

PeptideAtlas

More...PeptideAtlasi		P57057

PRoteomics IDEntifications database

More...PRIDEi		P57057

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		56976

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		P57057, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P57057

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P57057

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in numerous tissues, with highest expression in pancreas, kidney, bone marrow, spleen, liver, small intestine, as well as in fetal brain, liver and spleen.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000160190, Expressed in adenohypophysis and 175 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P57057, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P57057, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000160190, Tissue enhanced (intestine)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		119832, 6 interactors

Protein interaction database and analysis system

More...IntActi		P57057, 4 interactors

Molecular INTeraction database

More...MINTi		P57057

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000344648

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P57057, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2533, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159245

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_001265_31_6_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P57057

Identification of Orthologs from Complete Genome Data

More...OMAi		IQKELQC

Database of Orthologous Groups

More...OrthoDBi		964162at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P57057

TreeFam database of animal gene trees

More...TreeFami		TF314991

Family and domain databases

Conserved Domains Database

More...CDDi		cd17344, MFS_SLC37A1_2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.1250.20, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011701, MFS
IPR020846, MFS_dom
IPR036259, MFS_trans_sf
IPR044740, SLC37A1_2
IPR000849, Sugar_P_transporter

Pfam protein domain database

More...Pfami		View protein in Pfam
PF07690, MFS_1, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF002808, Hexose_phosphate_transp, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF103473, SSF103473, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50850, MFS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P57057-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARLPAGIRF IISFSRDQWY RAFIFILTFL LYASFHLSRK PISIVKGELH 
        60         70         80         90        100
KYCTAWDEAD VRFSSQNRKS GSAAPHQLPD NETDCGWAPF DKNNYQQLLG 
       110        120        130        140        150
ALDYSFLCAY AVGMYLSGII GERLPIRYYL TFGMLASGAF TALFGLGYFY 
       160        170        180        190        200
NIHSFGFYVV TQVINGLVQT TGWPSVVTCL GNWFGKGRRG LIMGVWNSHT 
       210        220        230        240        250
SVGNILGSLI AGYWVSTCWG LSFVVPGAIV AAMGIVCFLF LIEHPNDVRC 
       260        270        280        290        300
SSTLVTHSKG YENGTNRLRL QKQILKSEKN KPLDPEMQCL LLSDGKGSIH 
       310        320        330        340        350
PNHVVILPGD GGSGTAAISF TGALKIPGVI EFSLCLLFAK LVSYTFLFWL 
       360        370        380        390        400
PLYITNVDHL DAKKAGELST LFDVGGIFGG ILAGVISDRL EKRASTCGLM 
       410        420        430        440        450
LLLAAPTLYI FSTVSKMGLE ATIAMLLLSG ALVSGPYTLI TTAVSADLGT 
       460        470        480        490        500
HKSLKGNAHA LSTVTAIIDG TGSVGAALGP LLAGLLSPSG WSNVFYMLMF 
       510        520        530 
ADACALLFLI RLIHKELSCP GSATGDQVPF KEQ
Length:533
Mass (Da):57,648
Last modified:January 11, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFA978FE2943C80AA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DG69A0A0C4DG69_HUMAN
Glucose-6-phosphate exchanger SLC37...
SLC37A1
18Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti223F → L in AAG29853 (Ref. 2) Curated1
Sequence conflicti303H → Q in AAG29853 (Ref. 2) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_017110247D → N1 PublicationCorresponds to variant dbSNP:rs768541152Ensembl.1
Natural variantiVAR_017111414V → I1 PublicationCorresponds to variant dbSNP:rs228104Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AJ269529 mRNA Translation: CAB87248.1
AJ277912 mRNA Translation: CAB91985.1
AJ277913 mRNA Translation: CAB91986.1
AF311320 mRNA Translation: AAG29853.1
AP001625 Genomic DNA No translation available.
CH471079 Genomic DNA Translation: EAX09552.1
CH471079 Genomic DNA Translation: EAX09553.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS13689.1

NCBI Reference Sequences

More...RefSeqi		NP_001307466.1, NM_001320537.1
NP_061837.3, NM_018964.3
XP_016883866.1, XM_017028377.1
XP_016883867.1, XM_017028378.1
XP_016883868.1, XM_017028379.1
XP_016883869.1, XM_017028380.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000352133; ENSP00000344648; ENSG00000160190
ENST00000398341; ENSP00000381383; ENSG00000160190

Database of genes from NCBI RefSeq genomes

More...GeneIDi		54020

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:54020

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000352133.3; ENSP00000344648.2; NM_001320537.2; NP_001307466.1

UCSC genome browser

More...UCSCi		uc002zbi.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ269529 mRNA Translation: CAB87248.1
AJ277912 mRNA Translation: CAB91985.1
AJ277913 mRNA Translation: CAB91986.1
AF311320 mRNA Translation: AAG29853.1
AP001625 Genomic DNA No translation available.
CH471079 Genomic DNA Translation: EAX09552.1
CH471079 Genomic DNA Translation: EAX09553.1
CCDSiCCDS13689.1
RefSeqiNP_001307466.1, NM_001320537.1
NP_061837.3, NM_018964.3
XP_016883866.1, XM_017028377.1
XP_016883867.1, XM_017028378.1
XP_016883868.1, XM_017028379.1
XP_016883869.1, XM_017028380.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi119832, 6 interactors
IntActiP57057, 4 interactors
MINTiP57057
STRINGi9606.ENSP00000344648

Protein family/group databases

TCDBi2.A.1.4.7, the major facilitator superfamily (mfs)

PTM databases

GlyGeniP57057, 2 sites
iPTMnetiP57057
PhosphoSitePlusiP57057

Genetic variation databases

BioMutaiSLC37A1
DMDMi317373359

Proteomic databases

EPDiP57057
MassIVEiP57057
MaxQBiP57057
PaxDbiP57057
PeptideAtlasiP57057
PRIDEiP57057
ProteomicsDBi56976

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		23842, 82 antibodies from 19 providers

The DNASU plasmid repository

More...DNASUi		54020

Genome annotation databases

EnsembliENST00000352133; ENSP00000344648; ENSG00000160190
ENST00000398341; ENSP00000381383; ENSG00000160190
GeneIDi54020
KEGGihsa:54020
MANE-SelectiENST00000352133.3; ENSP00000344648.2; NM_001320537.2; NP_001307466.1
UCSCiuc002zbi.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		54020
DisGeNETi54020

GeneCards: human genes, protein and diseases

More...GeneCardsi		SLC37A1
HGNCiHGNC:11024, SLC37A1
HPAiENSG00000160190, Tissue enhanced (intestine)
MIMi608094, gene
neXtProtiNX_P57057
OpenTargetsiENSG00000160190
PharmGKBiPA35892
VEuPathDBiHostDB:ENSG00000160190

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2533, Eukaryota
GeneTreeiENSGT00940000159245
HOGENOMiCLU_001265_31_6_1
InParanoidiP57057
OMAiIQKELQC
OrthoDBi964162at2759
PhylomeDBiP57057
TreeFamiTF314991

Enzyme and pathway databases

PathwayCommonsiP57057
ReactomeiR-HSA-70263, Gluconeogenesis
SignaLinkiP57057

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		54020, 5 hits in 1045 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		SLC37A1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		54020
PharosiP57057, Tbio

Protein Ontology

More...PROi		PR:P57057
RNActiP57057, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000160190, Expressed in adenohypophysis and 175 other tissues
ExpressionAtlasiP57057, baseline and differential
GenevisibleiP57057, HS

Family and domain databases

CDDicd17344, MFS_SLC37A1_2, 1 hit
Gene3Di1.20.1250.20, 2 hits
InterProiView protein in InterPro
IPR011701, MFS
IPR020846, MFS_dom
IPR036259, MFS_trans_sf
IPR044740, SLC37A1_2
IPR000849, Sugar_P_transporter
PfamiView protein in Pfam
PF07690, MFS_1, 1 hit
PIRSFiPIRSF002808, Hexose_phosphate_transp, 1 hit
SUPFAMiSSF103473, SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850, MFS, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG6PT2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P57057
Secondary accession number(s): D3DSJ7, Q9HAQ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 11, 2011
Last modified: February 23, 2022
This is version 153 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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