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Entry version 124 (13 Feb 2019)
Sequence version 2 (06 Jun 2002)
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Protein

Oxygen-regulated protein 1

Gene

Rp1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • microtubule binding Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation, Sensory transduction, Vision

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Oxygen-regulated protein 1
Alternative name(s):
Retinitis pigmentosa RP1 protein homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rp1
Synonyms:Orp1, Rp1h
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1341105 Rp1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

As early as postnatal day 7, mice have already undergone significant molecular retinal changes. The molecular responses change dramatically during development and were distinct from responses to the disruption of the photoreceptor transcription factors Crx, Pde6b and Nrl. The JNK signaling cascades are specifically compromised in Rp1 defective retinas. Double heterozygotes of Rp1 and Rp1l1 exhibit abnormal outer segment morphology and reduced single rod photosensitivity and dark currents.2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000974111 – 2095Oxygen-regulated protein 1Add BLAST2095

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P56716

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P56716

PeptideAtlas

More...
PeptideAtlasi
P56716

PRoteomics IDEntifications database

More...
PRIDEi
P56716

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P56716

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P56716

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the cell bodies and inner segments of photoreceptors. Not found in liver, spleen, kidney, brain, thymus, muscle, heart, lung and testis.

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Gene expression is stimulated by retinal hypoxia and suppressed by relative retinal hyperoxia.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000025900 Expressed in 21 organ(s), highest expression level in retina

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P56716 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P56716 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via the doublecortin domains) with microtubules. Interacts with RP1L1. Interacts with MAK.3 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
202959, 2 interactors

Database of interacting proteins

More...
DIPi
DIP-59493N

Protein interaction database and analysis system

More...
IntActi
P56716, 3 interactors

Molecular INTeraction database

More...
MINTi
P56716

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000027032

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P56716

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P56716

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 117Doublecortin 1PROSITE-ProRule annotationAdd BLAST83
Domaini157 – 236Doublecortin 2PROSITE-ProRule annotationAdd BLAST80

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi655 – 660Poly-Lys6

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The doublecortin domains, which mediate interaction with microtubules, are required for regulation of microtubule polymerization and function in photoreceptor differentiation.By similarity

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1181 Eukaryota
KOG3757 Eukaryota
ENOG410ZE6Q LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154242

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000136857

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG018173

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P56716

KEGG Orthology (KO)

More...
KOi
K19538

Database of Orthologous Groups

More...
OrthoDBi
894392at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P56716

TreeFam database of animal gene trees

More...
TreeFami
TF318770

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01617 DCX, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.20.230, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003533 Doublecortin_dom
IPR036572 Doublecortin_dom_sf
IPR033013 Rp1
IPR040163 RP1/RP1L1

The PANTHER Classification System

More...
PANTHERi
PTHR23005 PTHR23005, 1 hit
PTHR23005:SF4 PTHR23005:SF4, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03607 DCX, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00537 DCX, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF89837 SSF89837, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50309 DC, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P56716-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDTPSTSFS MIHLTSEGQV PSPRHSNITH PVVAKRISFY KSGDPQFGGV
60 70 80 90 100
RVVVNPRSFK TFDALLDSLS RKVPLPFGVR NISTPRGRHS ITRLEELEDG
110 120 130 140 150
KSYVCSHNKK VLPVDLDKAR RRPRPWLSSR SISTHVQLCP ATANMSTMAP
160 170 180 190 200
GMLRAPRRLV VFRNGDPKNK HVVLLSRRIT QSFEAFLQYL TQVMQCPVAK
210 220 230 240 250
LYATDGRKVP SLQAVILSSG AVVAAGREPF KPGNYDIQKY LLPAKLPGIS
260 270 280 290 300
HRVHQKGKAK IEKRKMSTHM PSDLRPQTDS LISEKTYDCF SDFSVAPENY
310 320 330 340 350
LALETHESQS LSTYPSEDDV EKSIVFNQDG TMTVVMKVRF KIKEEETVKW
360 370 380 390 400
TTTVNRAGLS NNDEKNKKSS YPGKTDYGPS SLKLEACSLP EDIVDTTQQG
410 420 430 440 450
SLTEEENTQM TEQQALSCSS ASWENASMET DIQESQKQVK HFYRPPTPGP
460 470 480 490 500
RRMRQKKSVI GTVTVVSETE VQEKQFSYSE ERKGGEKSEY HMFTHSCSKM
510 520 530 540 550
SSVSNKLVQI GSDNEMESAL ERTRESGSLK SQAINAGAIE ITSQKVLKMC
560 570 580 590 600
HNNALPSTAP ENSVVEEGTD NSAVSGTATI KHFRTCGNAN DSFSSITADS
610 620 630 640 650
TPTSVNNYSN DRNISELPSV GSPVLTMRLV NEFAHCGLTE KPENRKKVLS
660 670 680 690 700
SSASKKKKKK SQQRMITSND KKKVIETKGP PNIAGKIPRA GTTAQERLLQ
710 720 730 740 750
ESDCPDKGGR VCEQGLNISP MAIESNNFFP KSNPTFSKNF YKNKLNTFQN
760 770 780 790 800
PKTQKLLAKR KSRPRKIVST ERLRKQEIGQ EDKILLHSDS KLCESHLEKQ
810 820 830 840 850
SLFHVFNILE EDQKVLHRPP FQVEKVARNL KGMAKKSLVP KVNDLHIMLR
860 870 880 890 900
NQKKQMGVKL KSGAEVSEQH VTTRADPLAS LKKPDFPEGI PHHSGKSYVK
910 920 930 940 950
RWLQNINSYP DFEHRKSGPL CQNRSDVVNY NRNGFLGNNL HTTSSKGNGF
960 970 980 990 1000
LMESNKSKTK NDNWSGNTNQ ETGKSLVAKD NGEELNKHHC ESQNGSLYDS
1010 1020 1030 1040 1050
YLVSLHDNCT LSQTTINEPS TKSHLSIEKS RPEVKLVYQE MNFATKRQSI
1060 1070 1080 1090 1100
EVAIQVDTMG ENVLKDYLPA LLLRHLEAFV PNNQKHQNGI SQIPGSLAEV
1110 1120 1130 1140 1150
VFPSVIDNSS TNLLLAWLLV LNLKRTMNSF CQSDAHKMTN RPSETAALLE
1160 1170 1180 1190 1200
VLKHVAITEE ADDLKAAVAN LMESTKTCSG SSGREQDMLP VNCTASSLHS
1210 1220 1230 1240 1250
VDECNENGSA QKTLLDEGYS VMGDCTSEMV SKSCNSSCEM HMVSKTNPPK
1260 1270 1280 1290 1300
QVDDQSDGLL TSNSCTVSQR STGACFLTDG VYSHEACAQK EGVYEGACLS
1310 1320 1330 1340 1350
DETHIPIRDC HTIHSVHSKE NKCTDDLEST EELKTVDKVP KGLSILADSM
1360 1370 1380 1390 1400
YKNDSNVSTF QNVNKLSSQR TLLSKTYLDS DKDYSPLEEF QNCPRKKIVN
1410 1420 1430 1440 1450
KKKSISSDKE ESRTSEEPRS ITNSMTSSER NAISELESFE ELESQDTSIF
1460 1470 1480 1490 1500
NMNVRAEKKS TKETMQKQSE ARMSSELINV SGRKIIEQER RNTAILETTA
1510 1520 1530 1540 1550
RGQVTPPSLA FCYDSNKNTE KEISEGETKM RVKKMVDSME NESYSESSLN
1560 1570 1580 1590 1600
FKKHHRSPGT LDWSDYGSDS ESGYPCKASS NSHNDDSGQE KEPTRGIVKR
1610 1620 1630 1640 1650
AIEKLYGKAE IIKPPFFHGS IHKSQVCPYN SVEVQCAKKT NFYESECQSL
1660 1670 1680 1690 1700
VSSEQVSRSS LIFQEFPQVD ANGMGDSFGD SSIENVTKSS AHDRVFTEKE
1710 1720 1730 1740 1750
NGKLIDNGKW LLRENHLWRV SSDNPGMYGN ADTTSVDTLI DKNSIEVPYS
1760 1770 1780 1790 1800
HFGELAPGPT MAELSSSEIE EMTQPLEVKC NYFNFPHGSD SEPFGEDFPD
1810 1820 1830 1840 1850
AQNKTCPKEK IPNHHTEEKG NYPSERLCTS VTQAFVSAGN KVHPVCSDAI
1860 1870 1880 1890 1900
KTQPLPGSNI THGALQEGDS LDKLYALCGQ HCPILTVIIQ PVNEESRGFA
1910 1920 1930 1940 1950
YRKDSDIENS LDFQLWMKIY PFMPQSKKHV FRSDGRNVSV GEEFAGNVIG
1960 1970 1980 1990 2000
DLCDQLYFKS MIDLVDQRAN SLGKEINLKK FQLYLKKSFS DPLSTSLLVV
2010 2020 2030 2040 2050
ENRNSVSLSP SSWTDNFKSI DENNNFLNRL PNSSKNPNQV VRENTNFQFH
2060 2070 2080 2090
LELFGQVYLL DICQVEKPLN IKTRSKLEMY YILEGEVLFI WEEEK
Length:2,095
Mass (Da):234,388
Last modified:June 6, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCA5301316633BD62
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A6YXU6A0A0A6YXU6_MOUSE
Oxygen-regulated protein 1
Rp1
285Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LHJ6A0A140LHJ6_MOUSE
Oxygen-regulated protein 1
Rp1
1,371Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF155141 mRNA Translation: AAD42089.2
AF291754 Genomic DNA Translation: AAM17919.1
BC120927 mRNA Translation: AAI20928.1
BC120928 mRNA Translation: AAI20929.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14804.1

NCBI Reference Sequences

More...
RefSeqi
NP_035413.1, NM_011283.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.294263

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000027032; ENSMUSP00000027032; ENSMUSG00000025900

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
19888

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:19888

UCSC genome browser

More...
UCSCi
uc007aex.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF155141 mRNA Translation: AAD42089.2
AF291754 Genomic DNA Translation: AAM17919.1
BC120927 mRNA Translation: AAI20928.1
BC120928 mRNA Translation: AAI20929.1
CCDSiCCDS14804.1
RefSeqiNP_035413.1, NM_011283.2
UniGeneiMm.294263

3D structure databases

ProteinModelPortaliP56716
SMRiP56716
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi202959, 2 interactors
DIPiDIP-59493N
IntActiP56716, 3 interactors
MINTiP56716
STRINGi10090.ENSMUSP00000027032

PTM databases

iPTMnetiP56716
PhosphoSitePlusiP56716

Proteomic databases

MaxQBiP56716
PaxDbiP56716
PeptideAtlasiP56716
PRIDEiP56716

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000027032; ENSMUSP00000027032; ENSMUSG00000025900
GeneIDi19888
KEGGimmu:19888
UCSCiuc007aex.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6101
MGIiMGI:1341105 Rp1

Phylogenomic databases

eggNOGiKOG1181 Eukaryota
KOG3757 Eukaryota
ENOG410ZE6Q LUCA
GeneTreeiENSGT00940000154242
HOGENOMiHOG000136857
HOVERGENiHBG018173
InParanoidiP56716
KOiK19538
OrthoDBi894392at2759
PhylomeDBiP56716
TreeFamiTF318770

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Cyp4a10 mouse

Protein Ontology

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PROi
PR:P56716

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000025900 Expressed in 21 organ(s), highest expression level in retina
ExpressionAtlasiP56716 baseline and differential
GenevisibleiP56716 MM

Family and domain databases

CDDicd01617 DCX, 2 hits
Gene3Di3.10.20.230, 2 hits
InterProiView protein in InterPro
IPR003533 Doublecortin_dom
IPR036572 Doublecortin_dom_sf
IPR033013 Rp1
IPR040163 RP1/RP1L1
PANTHERiPTHR23005 PTHR23005, 1 hit
PTHR23005:SF4 PTHR23005:SF4, 1 hit
PfamiView protein in Pfam
PF03607 DCX, 2 hits
SMARTiView protein in SMART
SM00537 DCX, 2 hits
SUPFAMiSSF89837 SSF89837, 2 hits
PROSITEiView protein in PROSITE
PS50309 DC, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRP1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P56716
Secondary accession number(s): Q548Q8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: June 6, 2002
Last modified: February 13, 2019
This is version 124 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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