UniProtKB - P56555 (DSCR4_HUMAN)
Protein
Down syndrome critical region protein 4
Gene
DSCR4
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Down syndrome critical region protein 4Alternative name(s): Down syndrome critical region protein B |
Gene namesi | Name:DSCR4 Synonyms:DCRB, DSCRB |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000184029.9 |
HGNCi | HGNC:3045, DSCR4 |
MIMi | 604829, gene |
neXtProti | NX_P56555 |
Pathology & Biotechi
Organism-specific databases
PharmGKBi | PA27497 |
Miscellaneous databases
Pharosi | P56555, Tdark |
Polymorphism and mutation databases
BioMutai | DSCR4 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000080019 | 1 – 118 | Down syndrome critical region protein 4Add BLAST | 118 |
Proteomic databases
PaxDbi | P56555 |
PRIDEi | P56555 |
ProteomicsDBi | 56925 |
PTM databases
iPTMneti | P56555 |
PhosphoSitePlusi | P56555 |
Expressioni
Tissue specificityi
Mainly expressed in placenta.
Gene expression databases
Bgeei | ENSG00000184029, Expressed in vastus lateralis and 18 other tissues |
Genevisiblei | P56555, HS |
Interactioni
Protein-protein interaction databases
BioGRIDi | 115570, 3 interactors |
IntActi | P56555, 3 interactors |
STRINGi | 9606.ENSP00000328676 |
Miscellaneous databases
RNActi | P56555, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502TEH5, Eukaryota |
HOGENOMi | CLU_2084115_0_0_1 |
InParanoidi | P56555 |
i Sequence
Sequence statusi: Complete.
P56555-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLIILTRDD EPRIFTPDSD AASPALHSTS PLPDPASASP LHREEKILPK
60 70 80 90 100
VCNIVSCLSF SLPASPTDSG LASPTIITRE GQQFWAKCLI WKYQLYLHGL
110
HKKSDGRRDK QISASPST
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB000099 mRNA Translation: BAA25877.1 BC069729 mRNA Translation: AAH69729.1 BC096162 mRNA Translation: AAH96162.1 BC096163 mRNA Translation: AAH96163.1 BC096164 mRNA Translation: AAH96164.1 |
RefSeqi | NP_005858.1, NM_005867.3 |
Genome annotation databases
UCSCi | uc002ywp.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB000099 mRNA Translation: BAA25877.1 BC069729 mRNA Translation: AAH69729.1 BC096162 mRNA Translation: AAH96162.1 BC096163 mRNA Translation: AAH96163.1 BC096164 mRNA Translation: AAH96164.1 |
RefSeqi | NP_005858.1, NM_005867.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 115570, 3 interactors |
IntActi | P56555, 3 interactors |
STRINGi | 9606.ENSP00000328676 |
PTM databases
iPTMneti | P56555 |
PhosphoSitePlusi | P56555 |
Polymorphism and mutation databases
BioMutai | DSCR4 |
Proteomic databases
PaxDbi | P56555 |
PRIDEi | P56555 |
ProteomicsDBi | 56925 |
Protocols and materials databases
DNASUi | 10281 |
Genome annotation databases
UCSCi | uc002ywp.3, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000184029.9 |
GeneCardsi | DSCR4 |
HGNCi | HGNC:3045, DSCR4 |
MIMi | 604829, gene |
neXtProti | NX_P56555 |
PharmGKBi | PA27497 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502TEH5, Eukaryota |
HOGENOMi | CLU_2084115_0_0_1 |
InParanoidi | P56555 |
Enzyme and pathway databases
PathwayCommonsi | P56555 |
Miscellaneous databases
BioGRID-ORCSi | 10281, 354 hits in 841 CRISPR screens |
ChiTaRSi | DSCR4, human |
GenomeRNAii | 10281 |
Pharosi | P56555, Tdark |
PROi | PR:P56555 |
RNActi | P56555, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000184029, Expressed in vastus lateralis and 18 other tissues |
Genevisiblei | P56555, HS |
Family and domain databases
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DSCR4_HUMAN | |
Accessioni | P56555Primary (citable) accession number: P56555 Secondary accession number(s): Q4VB31 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | July 15, 1998 | |
Last modified: | December 2, 2020 | |
This is version 108 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - Human chromosome 21
Human chromosome 21: entries, gene names and cross-references to MIM