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Protein

Defensin-like protein

Gene
N/A
Organism
Pentadiplandra brazzeana
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Taste-modifying protein; sweet-tasting. It is 2000 sweeter than sucrose on a molar basis.1 Publication
Has a pH-specific antimicrobial activity against bacteria (B.subtilis, E.coli and S.aureus) and the fungus C.albicans.1 Publication

GO - Biological processi

Keywordsi

Molecular functionAntibiotic, Antimicrobial, Fungicide, Taste-modifying protein

Names & Taxonomyi

Protein namesi
Recommended name:
Defensin-like protein
Alternative name(s):
Brazzein
OrganismiPentadiplandra brazzeana
Taxonomic identifieri43545 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesPentadiplandraceaePentadiplandra

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002214271 – 54Defensin-like proteinAdd BLAST54

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1Pyrrolidone carboxylic acid1 Publication1
Disulfide bondi4 ↔ 52
Disulfide bondi16 ↔ 37
Disulfide bondi22 ↔ 47
Disulfide bondi26 ↔ 49

Keywords - PTMi

Disulfide bond, Pyrrolidone carboxylic acid

Interactioni

Subunit structurei

Monomer.

Structurei

Secondary structure

154
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

DisProtiDP00582
ProteinModelPortaliP56552
SMRiP56552
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP56552

Family & Domainsi

Sequence similaritiesi

Belongs to the DEFL family.Curated

Family and domain databases

Gene3Di3.30.30.10, 1 hit
InterProiView protein in InterPro
IPR036574 Scorpion_toxin-like_sf
SUPFAMiSSF57095 SSF57095, 1 hit

Sequencei

Sequence statusi: Complete.

P56552-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
QDKCKKVYEN YPVSKCQLAN QCNYDCKLDK HARSGECFYD EKRNLQCICD

YCEY
Length:54
Mass (Da):6,498
Last modified:July 15, 1998 - v1
Checksum:i5BAB4D7215291252
GO

Sequence databases

PIRiS51208

Cross-referencesi

Sequence databases

PIRiS51208

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BRZNMR-A2-54[»]
2BRZNMR-A2-54[»]
2KGQNMR-A2-54[»]
2KYQNMR-A3-54[»]
2LY5NMR-A2-54[»]
2LY6NMR-A2-54[»]
2N66NMR-A1-54[»]
2N69NMR-A1-54[»]
4HE7X-ray1.80A1-54[»]
DisProtiDP00582
ProteinModelPortaliP56552
SMRiP56552
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP56552

Family and domain databases

Gene3Di3.30.30.10, 1 hit
InterProiView protein in InterPro
IPR036574 Scorpion_toxin-like_sf
SUPFAMiSSF57095 SSF57095, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiDEF_PENBA
AccessioniPrimary (citable) accession number: P56552
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 15, 1998
Last modified: October 25, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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