Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - P56470 (LEG4_HUMAN)

Entry version 179 (07 Apr 2021)
Sequence version 1 (15 Jul 1998)
Previous versions | rss
Add a publicationFeedback
Protein

Galectin-4

Gene

LGALS4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandLectin

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P56470

Protein family/group databases

UniLectin database of carbohydrate-binding proteins

More...UniLectini		P56470

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Galectin-4
Short name:
Gal-4
Alternative name(s):
Antigen NY-CO-27
L-36 lactose-binding protein
Short name:
L36LBP
Lactose-binding lectin 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LGALS4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:6565, LGALS4

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		602518, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P56470

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000171747.8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		3960

Open Targets

More...OpenTargetsi		ENSG00000171747

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA30342

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P56470, Tchem

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL1671608

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		LGALS4

Domain mapping of disease mutations (DMDM)

More...DMDMi		3024079

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000769341 – 323Galectin-4Add BLAST323

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei258PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P56470

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P56470

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P56470

PeptideAtlas

More...PeptideAtlasi		P56470

PRoteomics IDEntifications database

More...PRIDEi		P56470

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		56919

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P56470

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P56470

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000171747, Expressed in mucosa of transverse colon and 127 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P56470, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P56470, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000171747, Group enriched (gallbladder, intestine, lymphoid tissue)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		110151, 17 interactors

Protein interaction database and analysis system

More...IntActi		P56470, 16 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000302100

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		P56470

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P56470, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1323
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P56470

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P56470

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini19 – 150Galectin 1PROSITE-ProRule annotationAdd BLAST132
Domaini194 – 323Galectin 2PROSITE-ProRule annotationAdd BLAST130

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni256 – 262Beta-galactoside bindingBy similarity7

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Contains two homologous but distinct carbohydrate-binding domains.

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3587, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000160378

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_037794_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P56470

Identification of Orthologs from Complete Genome Data

More...OMAi		NPPVPYF

Database of Orthologous Groups

More...OrthoDBi		829777at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P56470

TreeFam database of animal gene trees

More...TreeFami		TF315551

Family and domain databases

Conserved Domains Database

More...CDDi		cd00070, GLECT, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR044156, Galectin-like
IPR015533, Galectin4/6
IPR001079, Galectin_CRD

The PANTHER Classification System

More...PANTHERi		PTHR11346, PTHR11346, 1 hit
PTHR11346:SF32, PTHR11346:SF32, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00337, Gal-bind_lectin, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00908, Gal-bind_lectin, 2 hits
SM00276, GLECT, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49899, SSF49899, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51304, GALECTIN, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P56470-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAYVPAPGYQ PTYNPTLPYY QPIPGGLNVG MSVYIQGVAS EHMKRFFVNF 
        60         70         80         90        100
VVGQDPGSDV AFHFNPRFDG WDKVVFNTLQ GGKWGSEERK RSMPFKKGAA 
       110        120        130        140        150
FELVFIVLAE HYKVVVNGNP FYEYGHRLPL QMVTHLQVDG DLQLQSINFI 
       160        170        180        190        200
GGQPLRPQGP PMMPPYPGPG HCHQQLNSLP TMEGPPTFNP PVPYFGRLQG 
       210        220        230        240        250
GLTARRTIII KGYVPPTGKS FAINFKVGSS GDIALHINPR MGNGTVVRNS 
       260        270        280        290        300
LLNGSWGSEE KKITHNPFGP GQFFDLSIRC GLDRFKVYAN GQHLFDFAHR 
       310        320 
LSAFQRVDTL EIQGDVTLSY VQI
Length:323
Mass (Da):35,941
Last modified:July 15, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE79EC0A9AB3990EF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QZ93M0QZ93_HUMAN
Galectin
LGALS4
218Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R349M0R349_HUMAN
Galectin-4
LGALS4
31Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R1B2M0R1B2_HUMAN
Galectin-4
LGALS4
38Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04976916T → M. Corresponds to variant dbSNP:rs8106404EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB006781 mRNA Translation: BAA22165.1
AF014838 mRNA Translation: AAC51763.1
U82953 mRNA Translation: AAB86590.1
BC003661 mRNA Translation: AAH03661.1
BC005146 mRNA Translation: AAH05146.1
BC034750 mRNA Translation: AAH34750.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12521.1

NCBI Reference Sequences

More...RefSeqi		NP_006140.1, NM_006149.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000307751; ENSP00000302100; ENSG00000171747
ENST00000634573; ENSP00000489411; ENSG00000282992

Database of genes from NCBI RefSeq genomes

More...GeneIDi		3960

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:3960

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Functional Glycomics Gateway - Glycan Binding

Galectin-4

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006781 mRNA Translation: BAA22165.1
AF014838 mRNA Translation: AAC51763.1
U82953 mRNA Translation: AAB86590.1
BC003661 mRNA Translation: AAH03661.1
BC005146 mRNA Translation: AAH05146.1
BC034750 mRNA Translation: AAH34750.1
CCDSiCCDS12521.1
RefSeqiNP_006140.1, NM_006149.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1X50NMR-A173-323[»]
4XZPX-ray1.48A1-152[»]
4YLZX-ray2.10A/B/C/D171-323[»]
4YM0X-ray2.30A/B/C/D171-323[»]
4YM1X-ray2.00A/B/C/D171-323[»]
4YM2X-ray2.10A/B/C/D171-323[»]
4YM3X-ray1.89A/B/C/D171-323[»]
5CBLX-ray1.78A/B/C/D179-323[»]
5DUUX-ray2.00A/B/C/D1-155[»]
5DUVX-ray1.90A/B/C/D1-155[»]
5DUWX-ray1.70A/B/C/D1-155[»]
5DUXX-ray1.85A/B/C/D1-155[»]
SMRiP56470
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi110151, 17 interactors
IntActiP56470, 16 interactors
STRINGi9606.ENSP00000302100

Chemistry databases

BindingDBiP56470
ChEMBLiCHEMBL1671608

Protein family/group databases

UniLectiniP56470

PTM databases

iPTMnetiP56470
PhosphoSitePlusiP56470

Genetic variation databases

BioMutaiLGALS4
DMDMi3024079

Proteomic databases

jPOSTiP56470
MassIVEiP56470
PaxDbiP56470
PeptideAtlasiP56470
PRIDEiP56470
ProteomicsDBi56919

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		30166, 360 antibodies

The DNASU plasmid repository

More...DNASUi		3960

Genome annotation databases

EnsembliENST00000307751; ENSP00000302100; ENSG00000171747
ENST00000634573; ENSP00000489411; ENSG00000282992
GeneIDi3960
KEGGihsa:3960

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		3960
DisGeNETi3960

GeneCards: human genes, protein and diseases

More...GeneCardsi		LGALS4
HGNCiHGNC:6565, LGALS4
HPAiENSG00000171747, Group enriched (gallbladder, intestine, lymphoid tissue)
MIMi602518, gene
neXtProtiNX_P56470
OpenTargetsiENSG00000171747
PharmGKBiPA30342
VEuPathDBiHostDB:ENSG00000171747.8

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3587, Eukaryota
GeneTreeiENSGT00940000160378
HOGENOMiCLU_037794_1_0_1
InParanoidiP56470
OMAiNPPVPYF
OrthoDBi829777at2759
PhylomeDBiP56470
TreeFamiTF315551

Enzyme and pathway databases

PathwayCommonsiP56470

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		3960, 7 hits in 982 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		LGALS4, human
EvolutionaryTraceiP56470

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		LGALS4

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		3960
PharosiP56470, Tchem

Protein Ontology

More...PROi		PR:P56470
RNActiP56470, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000171747, Expressed in mucosa of transverse colon and 127 other tissues
ExpressionAtlasiP56470, baseline and differential
GenevisibleiP56470, HS

Family and domain databases

CDDicd00070, GLECT, 2 hits
InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR044156, Galectin-like
IPR015533, Galectin4/6
IPR001079, Galectin_CRD
PANTHERiPTHR11346, PTHR11346, 1 hit
PTHR11346:SF32, PTHR11346:SF32, 1 hit
PfamiView protein in Pfam
PF00337, Gal-bind_lectin, 2 hits
SMARTiView protein in SMART
SM00908, Gal-bind_lectin, 2 hits
SM00276, GLECT, 2 hits
SUPFAMiSSF49899, SSF49899, 2 hits
PROSITEiView protein in PROSITE
PS51304, GALECTIN, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLEG4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P56470
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 15, 1998
Last modified: April 7, 2021
This is version 179 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again