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Protein

Ribosomal RNA processing protein 1 homolog A

Gene

RRP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a critical role in the generation of 28S rRNA.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • rRNA processing Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processrRNA processing

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ribosomal RNA processing protein 1 homolog A
Alternative name(s):
Novel nuclear protein 1
Short name:
NNP-1
Nucleolar protein Nop52
RRP1-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RRP1
Synonyms:D21S2056E, NNP1, NOP52, RRP1A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000160214.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18785 RRP1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610653 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P56182

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi427Q → R: Abolishes methylation by N6AMT1. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
8568

Open Targets

More...
OpenTargetsi
ENSG00000160214

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162402091

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RRP1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
2829451

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000968871 – 461Ribosomal RNA processing protein 1 homolog AAdd BLAST461

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei245PhosphoserineCombined sources1
Modified residuei247PhosphoserineCombined sources1
Modified residuei250PhosphoserineCombined sources1
Modified residuei251PhosphoserineCombined sources1
Modified residuei383PhosphoserineCombined sources1
Modified residuei412PhosphothreonineCombined sources1
Modified residuei427N5-methylglutamine1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Methylated at Gln-427 by N6AMT1.1 Publication

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P56182

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P56182

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P56182

PeptideAtlas

More...
PeptideAtlasi
P56182

PRoteomics IDEntifications database

More...
PRIDEi
P56182

ProteomicsDB human proteome resource

More...
ProteomicsDBi
56901

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...
SWISS-2DPAGEi
P56182

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P56182

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P56182

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed in fetal and adult tissues.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000160214 Expressed in 214 organ(s), highest expression level in amniotic fluid

CleanEx database of gene expression profiles

More...
CleanExi
HS_RRP1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P56182 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P56182 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA016818
HPA018166

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with C1QBP (PubMed:21536856). Interacts with RRP1B (PubMed:20926688).2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
RRP1BQ146842EBI-2880285,EBI-372051

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
114137, 36 interactors

Protein interaction database and analysis system

More...
IntActi
P56182, 15 interactors

Molecular INTeraction database

More...
MINTi
P56182

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000417464

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P56182

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P56182

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RRP1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3911 Eukaryota
ENOG4111GJ6 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011821

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG000394

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P56182

KEGG Orthology (KO)

More...
KOi
K14849

Identification of Orthologs from Complete Genome Data

More...
OMAi
QTMIREW

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0AX5

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P56182

TreeFam database of animal gene trees

More...
TreeFami
TF315294

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010301 Nop52

The PANTHER Classification System

More...
PANTHERi
PTHR13026 PTHR13026, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05997 Nop52, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P56182-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSRVQLPPE IQLAQRLAGN EQVTRDRAVR KLRKYIVART QRAAGGFTHD
60 70 80 90 100
ELLKVWKGLF YCMWMQDKPL LQEELGRTIS QLVHAFQTTE AQHLFLQAFW
110 120 130 140 150
QTMNREWTGI DRLRLDKFYM LMRMVLNESL KVLKMQGWEE RQIEELLELL
160 170 180 190 200
MTEILHPSSQ APNGVKSHFI EIFLEELTKV GAEELTADQN LKFIDPFCRI
210 220 230 240 250
AARTKDSLVL NNITRGIFET IVEQAPLAIE DLLNELDTQD EEVASDSDES
260 270 280 290 300
SEGGERGDAL SQKRSEKPPA GSICRAEPEA GEEQAGDDRD SGGPVLQFDY
310 320 330 340 350
EAVANRLFEM ASRQSTPSQN RKRLYKVIRK LQDLAGGIFP EDEIPEKACR
360 370 380 390 400
RLLEGRRQKK TKKQKRLLRL QQERGKGEKE PPSPGMERKR SRRRGVGADP
410 420 430 440 450
EARAEAGEQP GTAERALLRD QPRGRGQRGA RQRRRTPRPL TSARAKAANV
460
QEPEKKKKRR E
Length:461
Mass (Da):52,839
Last modified:November 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC6F204EF4161AEAE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RE82D6RE82_HUMAN
Ribosomal RNA-processing protein 1 ...
RRP1
45Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_053894194I → V. Corresponds to variant dbSNP:rs34224504Ensembl.1
Natural variantiVAR_053895326K → R1 PublicationCorresponds to variant dbSNP:rs915770Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U79775 mRNA Translation: AAC51625.1
AP001752 Genomic DNA Translation: BAA95542.1
BC000380 mRNA Translation: AAH00380.1
AL137757 mRNA Translation: CAB70909.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS42951.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T46485

NCBI Reference Sequences

More...
RefSeqi
NP_003674.1, NM_003683.5

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.110757

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000497547; ENSP00000417464; ENSG00000160214

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8568

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:8568

UCSC genome browser

More...
UCSCi
uc002zds.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U79775 mRNA Translation: AAC51625.1
AP001752 Genomic DNA Translation: BAA95542.1
BC000380 mRNA Translation: AAH00380.1
AL137757 mRNA Translation: CAB70909.1
CCDSiCCDS42951.1
PIRiT46485
RefSeqiNP_003674.1, NM_003683.5
UniGeneiHs.110757

3D structure databases

ProteinModelPortaliP56182
SMRiP56182
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi114137, 36 interactors
IntActiP56182, 15 interactors
MINTiP56182
STRINGi9606.ENSP00000417464

PTM databases

iPTMnetiP56182
PhosphoSitePlusiP56182

Polymorphism and mutation databases

BioMutaiRRP1
DMDMi2829451

2D gel databases

SWISS-2DPAGEiP56182

Proteomic databases

EPDiP56182
MaxQBiP56182
PaxDbiP56182
PeptideAtlasiP56182
PRIDEiP56182
ProteomicsDBi56901

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
8568
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000497547; ENSP00000417464; ENSG00000160214
GeneIDi8568
KEGGihsa:8568
UCSCiuc002zds.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8568
DisGeNETi8568
EuPathDBiHostDB:ENSG00000160214.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RRP1
HGNCiHGNC:18785 RRP1
HPAiHPA016818
HPA018166
MIMi610653 gene
neXtProtiNX_P56182
OpenTargetsiENSG00000160214
PharmGKBiPA162402091

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3911 Eukaryota
ENOG4111GJ6 LUCA
GeneTreeiENSGT00390000011821
HOVERGENiHBG000394
InParanoidiP56182
KOiK14849
OMAiQTMIREW
OrthoDBiEOG091G0AX5
PhylomeDBiP56182
TreeFamiTF315294

Enzyme and pathway databases

ReactomeiR-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RRP1 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
RRP1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
8568

Protein Ontology

More...
PROi
PR:P56182

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000160214 Expressed in 214 organ(s), highest expression level in amniotic fluid
CleanExiHS_RRP1
ExpressionAtlasiP56182 baseline and differential
GenevisibleiP56182 HS

Family and domain databases

InterProiView protein in InterPro
IPR010301 Nop52
PANTHERiPTHR13026 PTHR13026, 1 hit
PfamiView protein in Pfam
PF05997 Nop52, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRRP1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P56182
Secondary accession number(s): Q9NST5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 7, 2018
This is version 155 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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