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UniProtKB - P56108 (TAL_HELPY)
Protein
Transaldolase
Gene
tal
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Functioni
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
By similarityCatalytic activityi
- D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = β-D-fructose 6-phosphate + D-erythrose 4-phosphateEC:2.2.1.2
: pentose phosphate pathway Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage). This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 127 | Schiff-base intermediate with substrateBy similarity | 1 |
GO - Molecular functioni
- transaldolase activity Source: UniProtKB-UniRule
GO - Biological processi
- carbohydrate metabolic process Source: InterPro
- pentose-phosphate shunt Source: UniProtKB-UniRule
Keywordsi
Molecular function | Transferase |
Biological process | Pentose shunt |
Ligand | Schiff base |
Enzyme and pathway databases
UniPathwayi | UPA00115;UER00414 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:tal Ordered Locus Names:HP_1495 |
Organismi | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
Taxonomic identifieri | 85962 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm By similarity
Other locations
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000173631 | 1 – 316 | TransaldolaseAdd BLAST | 316 |
Proteomic databases
PaxDbi | P56108 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG0176, Bacteria |
OMAi | ATECYYQ |
PhylomeDBi | P56108 |
Family and domain databases
CDDi | cd00955, Transaldolase_like, 1 hit |
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_00493, Transaldolase_2, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR001585, TAL/FSA IPR004732, Transaldolase_2 IPR018225, Transaldolase_AS |
PANTHERi | PTHR10683, PTHR10683, 1 hit |
Pfami | View protein in Pfam PF00923, TAL_FSA, 1 hit |
PIRSFi | PIRSF036915, Trnald_Bac_Plnt, 1 hit |
TIGRFAMsi | TIGR00876, tal_mycobact, 1 hit |
PROSITEi | View protein in PROSITE PS01054, TRANSALDOLASE_1, 1 hit PS00958, TRANSALDOLASE_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P56108-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQEFSLWCDF IERDFLENDF LKLINKGAIC GATSNPSLFC EAITKSAFYK
60 70 80 90 100
DEIAKLKGKK AKEIYETLAL KDILQASSAL MPLYEKDPNN GYISLEIDPF
110 120 130 140 150
LEDDAAKSID EAKRLFKTLN RPNVMIKVPA SESGIEVVSA LTQASIPVNV
160 170 180 190 200
TLVFSPKIAG EIAQILAKEA QKRAVISVFV SRFDKEIDPL VPKNLQAQSG
210 220 230 240 250
IINATECYYQ INQHANKLTS TLFASTGVKS NSLAKDYYIK ALCFKNSINT
260 270 280 290 300
APLEALNAYL LDPNTECQTP LKTTEIEAFK KELKVHNIDL ENTAQKLLKE
310
GLIAFKQSFE KLLSSF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000511 Genomic DNA Translation: AAD08536.1 |
PIRi | G64706 |
RefSeqi | NP_208286.1, NC_000915.1 WP_001155041.1, NC_018939.1 |
Genome annotation databases
EnsemblBacteriai | AAD08536; AAD08536; HP_1495 |
KEGGi | hpy:HP_1495 |
PATRICi | fig|85962.47.peg.1607 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000511 Genomic DNA Translation: AAD08536.1 |
PIRi | G64706 |
RefSeqi | NP_208286.1, NC_000915.1 WP_001155041.1, NC_018939.1 |
3D structure databases
SMRi | P56108 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 85962.C694_07745 |
Proteomic databases
PaxDbi | P56108 |
Genome annotation databases
EnsemblBacteriai | AAD08536; AAD08536; HP_1495 |
KEGGi | hpy:HP_1495 |
PATRICi | fig|85962.47.peg.1607 |
Phylogenomic databases
eggNOGi | COG0176, Bacteria |
OMAi | ATECYYQ |
PhylomeDBi | P56108 |
Enzyme and pathway databases
UniPathwayi | UPA00115;UER00414 |
Family and domain databases
CDDi | cd00955, Transaldolase_like, 1 hit |
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_00493, Transaldolase_2, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR001585, TAL/FSA IPR004732, Transaldolase_2 IPR018225, Transaldolase_AS |
PANTHERi | PTHR10683, PTHR10683, 1 hit |
Pfami | View protein in Pfam PF00923, TAL_FSA, 1 hit |
PIRSFi | PIRSF036915, Trnald_Bac_Plnt, 1 hit |
TIGRFAMsi | TIGR00876, tal_mycobact, 1 hit |
PROSITEi | View protein in PROSITE PS01054, TRANSALDOLASE_1, 1 hit PS00958, TRANSALDOLASE_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | TAL_HELPY | |
Accessioni | P56108Primary (citable) accession number: P56108 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 112 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families