We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - P55985 (TRUD_HELPY)
Protein
tRNA pseudouridine synthase D
Gene
truD
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Functioni
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
UniRule annotationCatalytic activityi
- EC:5.4.99.27UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 81 | NucleophileUniRule annotation | 1 |
GO - Molecular functioni
- pseudouridine synthase activity Source: GO_Central
- RNA binding Source: InterPro
- tRNA pseudouridine synthase activity Source: UniProtKB-EC
GO - Biological processi
- pseudouridine synthesis Source: GO_Central
- tRNA pseudouridine synthesis Source: UniProtKB-UniRule
Keywordsi
Molecular function | Isomerase |
Biological process | tRNA processing |
Names & Taxonomyi
Protein namesi | Recommended name: tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)Alternative name(s): tRNA pseudouridine(13) synthaseUniRule annotation tRNA pseudouridylate synthase DUniRule annotation tRNA-uridine isomerase DUniRule annotation |
Gene namesi | Name:truDUniRule annotation Ordered Locus Names:HP_0926 |
Organismi | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
Taxonomic identifieri | 85962 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000152502 | 1 – 381 | tRNA pseudouridine synthase DAdd BLAST | 381 |
Proteomic databases
PaxDbi | P55985 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 160 – 335 | TRUDUniRule annotationAdd BLAST | 176 |
Sequence similaritiesi
Belongs to the pseudouridine synthase TruD family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0585, Bacteria |
OMAi | LWLWVEK |
PhylomeDBi | P55985 |
Family and domain databases
Gene3Di | 3.30.2350.20, 1 hit |
HAMAPi | MF_01082, TruD, 1 hit |
InterProi | View protein in InterPro IPR020103, PsdUridine_synth_cat_dom_sf IPR001656, PsdUridine_synth_TruD IPR020119, PsdUridine_synth_TruD_CS IPR011760, PsdUridine_synth_TruD_insert IPR042214, TruD_catalytic |
Pfami | View protein in Pfam PF01142, TruD, 1 hit |
PIRSFi | PIRSF037016, Pseudouridin_synth_euk_prd, 1 hit |
SUPFAMi | SSF55120, SSF55120, 1 hit |
TIGRFAMsi | TIGR00094, tRNA_TruD_broad, 1 hit |
PROSITEi | View protein in PROSITE PS50984, TRUD, 1 hit PS01268, UPF0024, 1 hit |
i Sequence
Sequence statusi: Complete.
P55985-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNLNFMPLLH AYNHASIDFH FNSSARDFCV HEVPLYEFSN TGEHAVIQVR
60 70 80 90 100
KSGLSTLEML QIFSQILGVR IAELGYAGLK DKNALTTQFI SLPKKYAPLL
110 120 130 140 150
EKNTSNFQEK NLKILSLNYH HNKIKLGHLK GNRFFMRFKK MTPLNAQKTK
160 170 180 190 200
QVLEQIAQFG MPNYFGSQRF GKFNDNHQEG LKILQNQTKF AHQKLNAFLI
210 220 230 240 250
SSYQSYLFNA LLSKRLEISK IISAFSVKEN LEFFKQKNLS VDSDTLKTLK
260 270 280 290 300
NQAHPFKILE GDVMCHYPYG KFFDALELEK EGERFLKKEV APTGLLDGKK
310 320 330 340 350
ALYAKNLSLE IEKEFQHNLL SSHAKTLGSR RFFWVFVENV TSQYVKEKAQ
360 370 380
FELGFYLPKG SYASALLKEI KHEKGENNDE F
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000511 Genomic DNA Translation: AAD07971.1 |
PIRi | F64635 |
RefSeqi | NP_207718.1, NC_000915.1 WP_001052415.1, NC_018939.1 |
Genome annotation databases
EnsemblBacteriai | AAD07971; AAD07971; HP_0926 |
KEGGi | hpy:HP_0926 |
PATRICi | fig|85962.47.peg.991 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000511 Genomic DNA Translation: AAD07971.1 |
PIRi | F64635 |
RefSeqi | NP_207718.1, NC_000915.1 WP_001052415.1, NC_018939.1 |
3D structure databases
SMRi | P55985 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 85962.C694_04765 |
Proteomic databases
PaxDbi | P55985 |
Genome annotation databases
EnsemblBacteriai | AAD07971; AAD07971; HP_0926 |
KEGGi | hpy:HP_0926 |
PATRICi | fig|85962.47.peg.991 |
Phylogenomic databases
eggNOGi | COG0585, Bacteria |
OMAi | LWLWVEK |
PhylomeDBi | P55985 |
Family and domain databases
Gene3Di | 3.30.2350.20, 1 hit |
HAMAPi | MF_01082, TruD, 1 hit |
InterProi | View protein in InterPro IPR020103, PsdUridine_synth_cat_dom_sf IPR001656, PsdUridine_synth_TruD IPR020119, PsdUridine_synth_TruD_CS IPR011760, PsdUridine_synth_TruD_insert IPR042214, TruD_catalytic |
Pfami | View protein in Pfam PF01142, TruD, 1 hit |
PIRSFi | PIRSF037016, Pseudouridin_synth_euk_prd, 1 hit |
SUPFAMi | SSF55120, SSF55120, 1 hit |
TIGRFAMsi | TIGR00094, tRNA_TruD_broad, 1 hit |
PROSITEi | View protein in PROSITE PS50984, TRUD, 1 hit PS01268, UPF0024, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | TRUD_HELPY | |
Accessioni | P55985Primary (citable) accession number: P55985 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 105 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families