Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome c oxidase subunit 5A, mitochondrial

Gene

cox-5A

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

GO - Molecular functioni

GO - Biological processi

  • mitochondrial electron transport, cytochrome c to oxygen Source: WormBase

Keywordsi

LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 5A, mitochondrial
Alternative name(s):
Cytochrome c oxidase polypeptide Va
Gene namesi
Name:cox-5AImported
Synonyms:cco-2Imported
ORF Names:Y37D8A.14Imported
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiY37D8A.14 ; CE20218 ; WBGene00012553 ; cox-5A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 29Mitochondrion1 PublicationAdd BLAST29
ChainiPRO_000000610330 – 174Cytochrome c oxidase subunit 5A, mitochondrialAdd BLAST145

Proteomic databases

EPDiP55954
PaxDbiP55954
PeptideAtlasiP55954
PRIDEiP55954

Expressioni

Gene expression databases

BgeeiWBGene00012553

Interactioni

Protein-protein interaction databases

BioGridi41880, 1 interactor
DIPiDIP-27022N
IntActiP55954, 1 interactor
STRINGi6239.Y37D8A.14.2

Structurei

3D structure databases

ProteinModelPortaliP55954
SMRiP55954
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG4077 Eukaryota
ENOG4111MPD LUCA
GeneTreeiENSGT00390000001424
HOGENOMiHOG000160656
InParanoidiP55954
KOiK02264
OMAiMEKWPAD
OrthoDBiEOG091G0FVR
PhylomeDBiP55954

Family and domain databases

CDDicd00923 Cyt_c_Oxidase_Va, 1 hit
Gene3Di1.25.40.40, 1 hit
InterProiView protein in InterPro
IPR003204 Cyt_c_oxidase_su5A/6
IPR036545 Cyt_c_oxidase_su5A/6_sf
PANTHERiPTHR14200 PTHR14200, 1 hit
PfamiView protein in Pfam
PF02284 COX5A, 1 hit
SUPFAMiSSF48479 SSF48479, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P55954-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASLTRAVTR LAIAGRQAVR TIATTTPVSG HGDDIMEKWP ADKFDNHFIN
60 70 80 90 100
YLNRPEIDGW EVRKALSELH DYDVIPDPKV VEAALRACRR VNDFALAVRF
110 120 130 140 150
LEAIKIKCGA QKNRDTVYAY IVKQVEPVLK ELGIDTPEQL GYGEPEFFVP
160 170
EPEYWWEKKW YKDYGYDKHP NIQI
Length:174
Mass (Da):20,111
Last modified:December 7, 2004 - v2
Checksum:iDAB897567143BF1C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti30G → H AA sequence (PubMed:9150941).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CAA21532.1
PIRiT26631
RefSeqiNP_499681.1, NM_067280.5
UniGeneiCel.8875

Genome annotation databases

EnsemblMetazoaiY37D8A.14; Y37D8A.14; WBGene00012553
GeneIDi176707
KEGGicel:CELE_Y37D8A.14
UCSCiY37D8A.14.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiCOX5A_CAEEL
AccessioniPrimary (citable) accession number: P55954
Secondary accession number(s): Q9XWV8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 7, 2004
Last modified: July 18, 2018
This is version 110 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health