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Protein

60S ribosomal protein L14

Gene

RpL14

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic translation Source: FlyBase
  • negative regulation of neuron apoptotic process Source: FlyBase
  • ribosomal large subunit biogenesis Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DME-72689 Formation of a pool of free 40S subunits
R-DME-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DME-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L14
Gene namesi
Name:RpL14
ORF Names:CG6253
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0017579 RpL14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001320341 – 16660S ribosomal protein L14Add BLAST166

Proteomic databases

PaxDbiP55841
PRIDEiP55841

Expressioni

Gene expression databases

BgeeiFBgn0017579
ExpressionAtlasiP55841 baseline and differential
GenevisibleiP55841 DM

Interactioni

Protein-protein interaction databases

BioGridi64391, 30 interactors
DIPiDIP-20649N
IntActiP55841, 14 interactors
MINTiP55841
STRINGi7227.FBpp0076359

Structurei

3D structure databases

ProteinModelPortaliP55841
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3421 Eukaryota
COG2163 LUCA
InParanoidiP55841
KOiK02875
OMAiSDFERFQ
OrthoDBiEOG091G0VTN
PhylomeDBiP55841

Family and domain databases

Gene3Di2.30.30.30, 1 hit
InterProiView protein in InterPro
IPR014722 Rib_L2_dom2
IPR002784 Ribosomal_L14e_dom
IPR008991 Translation_prot_SH3-like_sf
PfamiView protein in Pfam
PF01929 Ribosomal_L14e, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit

Sequencei

Sequence statusi: Complete.

P55841-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFERFVQTG RIAKASAGPL KGRLVAIVDV IDQNRVLVDG PLTGVPRQEY
60 70 80 90 100
RLNNLHLTKY RIKFPYTAPT RIVRKAWTES DLKAQWKVSP WSVKAQNICK
110 120 130 140 150
RSSLNDFDRF KLRYAKRQRN KLLTIAFNTL KKRTKADGTP RVLKKDRRER
160
LRAEKAKGGK KAAAKK
Length:166
Mass (Da):19,174
Last modified:November 1, 1997 - v1
Checksum:i8600358A902E6A67
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10015 Genomic DNA Translation: CAA71121.1
Y10017 mRNA Translation: CAA71124.1
Y09766 mRNA Translation: CAA70905.1
AE014296 Genomic DNA Translation: AAF50393.1
RefSeqiNP_523975.1, NM_079251.4
UniGeneiDm.895

Genome annotation databases

EnsemblMetazoaiFBtr0076633; FBpp0076359; FBgn0017579
GeneIDi38983
KEGGidme:Dmel_CG6253

Similar proteinsi

Entry informationi

Entry nameiRL14_DROME
AccessioniPrimary (citable) accession number: P55841
Secondary accession number(s): Q9VSM3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 18, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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