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Entry version 156 (16 Oct 2019)
Sequence version 3 (25 Nov 2008)
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Protein

SH3 domain-binding glutamic acid-rich protein

Gene

SH3BGR

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

It is uncertain whether Met-1 or Met-64 is the initiator.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SH3 domain-binding glutamic acid-rich protein
Short name:
SH3BGR protein
Alternative name(s):
21-glutamic acid-rich protein
Short name:
21-GARP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SH3BGR
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10822 SH3BGR

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
602230 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P55822

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
6450

Open Targets

More...
OpenTargetsi
ENSG00000185437

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA35730

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P55822

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SH3BGR

Domain mapping of disease mutations (DMDM)

More...
DMDMi
215274184

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002207431 – 239SH3 domain-binding glutamic acid-rich proteinAdd BLAST239

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P55822

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P55822

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P55822

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P55822

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P55822

PeptideAtlas

More...
PeptideAtlasi
P55822

PRoteomics IDEntifications database

More...
PRIDEi
P55822

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
56872 [P55822-1]
883

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P55822

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P55822

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in heart and skeletal muscle.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000185437 Expressed in 209 organ(s), highest expression level in vastus lateralis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P55822 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P55822 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB003685
HPA030690

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112348, 6 interactors

Protein interaction database and analysis system

More...
IntActi
P55822, 5 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000332513

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P55822

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi124 – 130SH3-bindingSequence analysis7

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi170 – 239Glu-rich (acidic)Add BLAST70

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SH3BGR family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SH3-binding

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4023 Eukaryota
ENOG4111N7M LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159847

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000037924

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P55822

Identification of Orthologs from Complete Genome Data

More...
OMAi
PLKLEWE

Database of Orthologous Groups

More...
OrthoDBi
1508713at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P55822

TreeFam database of animal gene trees

More...
TreeFami
TF105574

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03030 GRX_SH3BGR, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006993 Glut_rich_SH3-bd
IPR036249 Thioredoxin-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04908 SH3BGR, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52833 SSF52833, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P55822-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPLLLLGETE PLKLERDCRS PVDPWAAASP DLALACLCHC QDLSSGAFPD
60 70 80 90 100
RGVLGGVLFP TVEMVIKVFV ATSSGSIAIR KKQQEVVGFL EANKIDFKEL
110 120 130 140 150
DIAGDEDNRR WMRENVPGEK KPQNGIPLPP QIFNEEQYCG DFDSFFSAKE
160 170 180 190 200
ENIIYSFLGL APPPDSKGSE KAEEGGETEA QKEGSEDVGN LPEAQEKNEE
210 220 230
EGETATEETE EIAMEGAEGE AEEEEETAEG EEPGEDEDS
Length:239
Mass (Da):26,086
Last modified:November 25, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBA57B1C8034D6BBC
GO
Isoform 2 (identifier: P55822-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-111: Missing.

Note: No experimental confirmation available.
Show »
Length:128
Mass (Da):13,976
Checksum:i1E2E0AADFFAC0B28
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JJT2C9JJT2_HUMAN
SH3 domain-binding glutamic acid-ri...
SH3BGR
97Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C2G0H7C2G0_HUMAN
SH3 domain-binding glutamic acid-ri...
SH3BGR
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JX40C9JX40_HUMAN
SH3 domain-binding glutamic acid-ri...
SH3BGR
106Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C1Y8H7C1Y8_HUMAN
SH3 domain-binding glutamic acid-ri...
SH3BGR
54Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C3V3H7C3V3_HUMAN
SH3 domain-binding glutamic acid-ri...
SH3BGR
81Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti232E → EE in BM474020 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05718223D → E1 PublicationCorresponds to variant dbSNP:rs11575939Ensembl.1
Natural variantiVAR_05718350D → N2 PublicationsCorresponds to variant dbSNP:rs6517549Ensembl.1
Natural variantiVAR_028233188V → A1 PublicationCorresponds to variant dbSNP:rs9974333Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0457881 – 111Missing in isoform 2. 1 PublicationAdd BLAST111

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X93498 mRNA Translation: CAB57259.1
AL163279 Genomic DNA Translation: CAB90456.1
AL163280 Genomic DNA Translation: CAB90445.1
AF121781 Genomic DNA Translation: AAD12067.1
AF121897 Genomic DNA No translation available.
CH471079 Genomic DNA Translation: EAX09638.1
CH471079 Genomic DNA Translation: EAX09639.1
CH471079 Genomic DNA Translation: EAX09640.1
BC006371 mRNA Translation: AAH06371.1
BM474020 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13666.1 [P55822-1]
CCDS33560.1 [P55822-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001001713.1, NM_001001713.1 [P55822-2]
NP_001304671.1, NM_001317742.1 [P55822-2]
NP_031367.1, NM_007341.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000333634; ENSP00000332513; ENSG00000185437 [P55822-1]
ENST00000380631; ENSP00000370005; ENSG00000185437 [P55822-2]
ENST00000380634; ENSP00000370008; ENSG00000185437 [P55822-2]
ENST00000380637; ENSP00000370011; ENSG00000185437 [P55822-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6450

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6450

UCSC genome browser

More...
UCSCi
uc002yxz.4 human [P55822-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X93498 mRNA Translation: CAB57259.1
AL163279 Genomic DNA Translation: CAB90456.1
AL163280 Genomic DNA Translation: CAB90445.1
AF121781 Genomic DNA Translation: AAD12067.1
AF121897 Genomic DNA No translation available.
CH471079 Genomic DNA Translation: EAX09638.1
CH471079 Genomic DNA Translation: EAX09639.1
CH471079 Genomic DNA Translation: EAX09640.1
BC006371 mRNA Translation: AAH06371.1
BM474020 mRNA No translation available.
CCDSiCCDS13666.1 [P55822-1]
CCDS33560.1 [P55822-2]
RefSeqiNP_001001713.1, NM_001001713.1 [P55822-2]
NP_001304671.1, NM_001317742.1 [P55822-2]
NP_031367.1, NM_007341.2

3D structure databases

SMRiP55822
ModBaseiSearch...

Protein-protein interaction databases

BioGridi112348, 6 interactors
IntActiP55822, 5 interactors
STRINGi9606.ENSP00000332513

PTM databases

iPTMnetiP55822
PhosphoSitePlusiP55822

Polymorphism and mutation databases

BioMutaiSH3BGR
DMDMi215274184

Proteomic databases

EPDiP55822
jPOSTiP55822
MassIVEiP55822
MaxQBiP55822
PaxDbiP55822
PeptideAtlasiP55822
PRIDEiP55822
ProteomicsDBi56872 [P55822-1]
883

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6450

Genome annotation databases

EnsembliENST00000333634; ENSP00000332513; ENSG00000185437 [P55822-1]
ENST00000380631; ENSP00000370005; ENSG00000185437 [P55822-2]
ENST00000380634; ENSP00000370008; ENSG00000185437 [P55822-2]
ENST00000380637; ENSP00000370011; ENSG00000185437 [P55822-2]
GeneIDi6450
KEGGihsa:6450
UCSCiuc002yxz.4 human [P55822-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6450
DisGeNETi6450

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SH3BGR
HGNCiHGNC:10822 SH3BGR
HPAiCAB003685
HPA030690
MIMi602230 gene
neXtProtiNX_P55822
OpenTargetsiENSG00000185437
PharmGKBiPA35730

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4023 Eukaryota
ENOG4111N7M LUCA
GeneTreeiENSGT00940000159847
HOGENOMiHOG000037924
InParanoidiP55822
OMAiPLKLEWE
OrthoDBi1508713at2759
PhylomeDBiP55822
TreeFamiTF105574

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
SH3BGR

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
6450
PharosiP55822

Protein Ontology

More...
PROi
PR:P55822

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000185437 Expressed in 209 organ(s), highest expression level in vastus lateralis
ExpressionAtlasiP55822 baseline and differential
GenevisibleiP55822 HS

Family and domain databases

CDDicd03030 GRX_SH3BGR, 1 hit
InterProiView protein in InterPro
IPR006993 Glut_rich_SH3-bd
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF04908 SH3BGR, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSH3BG_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P55822
Secondary accession number(s): A6ND59, D3DSI2, Q9BRB8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 25, 2008
Last modified: October 16, 2019
This is version 156 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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