UniProtKB - P55795 (HNRH2_HUMAN)

BLAST

>sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1
MMLSTEGREGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVE
LESEEEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPF
GCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRY
IEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGY
GGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRGLPYRA
TENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELF
LNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGY
GGGYGGQSSMSGYDQVLQENSSDYQSNLA

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History
Entry version 200 (07 Nov 2018)
Sequence version 1 (01 Nov 1997)
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Protein

Heterogeneous nuclear ribonucleoprotein H2

Gene

HNRNPH2

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).

GO - Molecular functionⁱ

RNA binding
Source: UniProtKB
Inferred from high throughput direct assayⁱ
- 22658674
- 22681889

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

mRNA splicing, via spliceosome Source: Reactome
RNA metabolic process Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Ribonucleoprotein, RNA-binding

Molecular function

Ribonucleoprotein, RNA-binding

Enzyme and pathway databases

Reactomeⁱ	R-HSA-72163 mRNA Splicing - Major Pathway R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA

Reactomeⁱ

R-HSA-72163 mRNA Splicing - Major Pathway
R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Heterogeneous nuclear ribonucleoprotein H2 Short name: hnRNP H2 Alternative name(s): FTP-3 Heterogeneous nuclear ribonucleoprotein H' Short name: hnRNP H' Cleaved into the following chain: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed
Gene namesⁱ	Name:HNRNPH2 Synonyms:FTP3, HNRPH2
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome X

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000126945.8
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:5042 HNRNPH2
MIMⁱ	300610 gene
neXtProtⁱ	NX_P55795

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Mental retardation, X-linked, syndromic, Bain type (MRXSB)1 Publication

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionA form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRXSB patients manifest developmental delay, intellectual disability, autism, hypotonia, seizures, and dysmorphic facial features. Only females are affected.

Keywords - Diseaseⁱ

Disease mutation, Mental retardation

Organism-specific databases

DisGeNET More...DisGeNETⁱ	3188
MalaCards human disease database More...MalaCardsⁱ	HNRNPH2
MIMⁱ	300986 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000126945
PharmGKBⁱ	PA162391316

Polymorphism and mutation databases

BioMutaⁱ	HNRNPH2
DMDMⁱ	2500576

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Length
ChainⁱPRO_0000081859	1 – 449	Heterogeneous nuclear ribonucleoprotein H2Add BLAST	449
Initiator methionineⁱ		Removed; alternateBy similarity
ChainⁱPRO_0000434385	2 – 449	Heterogeneous nuclear ribonucleoprotein H2, N-terminally processedAdd BLAST	448

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	1	N-acetylmethionineCombined sources1 Publication	1
Modified residueⁱ	2	N-acetylmethionine; in Heterogeneous nuclear ribonucleoprotein H2, N-terminally processedBy similarity	1
Modified residueⁱ	23	PhosphoserineBy similarity	1
Cross-linkⁱ	35	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residueⁱ	54	PhosphoserineBy similarity	1
Modified residueⁱ	63	PhosphoserineBy similarity	1
Cross-linkⁱ	87	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	90	PhosphoserineBy similarity	1
Cross-linkⁱ	98	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	233	Dimethylated arginine; alternateBy similarity	1
Modified residueⁱ	233	Omega-N-methylarginine; alternateCombined sources	1
Modified residueⁱ	246	PhosphotyrosineBy similarity	1
Modified residueⁱ	310	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	P55795
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P55795
PaxDbⁱ	P55795
PeptideAtlas More...PeptideAtlasⁱ	P55795
PRIDEⁱ	P55795
ProteomicsDBⁱ	56867

2D gel databases

REPRODUCTION-2DPAGE More...REPRODUCTION-2DPAGEⁱ	IPI00026230

REPRODUCTION-2DPAGEⁱ

IPI00026230

PTM databases

iPTMnetⁱ	P55795
PhosphoSitePlusⁱ	P55795
SwissPalmⁱ	P55795

Expressionⁱ

Tissue specificityⁱ

Expressed ubiquitously.

Gene expression databases

Bgeeⁱ	ENSG00000126945 Expressed in 238 organ(s), highest expression level in choroid plexus epithelium
CleanExⁱ	HS_HNRNPH2
Genevisibleⁱ	P55795 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB004436 HPA000914 HPA001359 HPA016884

HPAⁱ

CAB004436
HPA000914
HPA001359
HPA016884

Interactionⁱ

Subunit structureⁱ

Interacts with TXNL4/DIM1.1 Publication

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
MSI2	Q96DH6	5	EBI-352823,EBI-2462339
TEKT1	Q969V4	5	EBI-352823,EBI-10180409

Protein-protein interaction databases

BioGridⁱ	109429, 191 interactors
IntActⁱ	P55795, 95 interactors
Molecular INTeraction database More...MINTⁱ	P55795
STRINGⁱ	9606.ENSP00000361927

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	112 – 117	Combined sources	6
Helixⁱ	124 – 130	Combined sources	7
Turnⁱ	131 – 133	Combined sources	3
Beta strandⁱ	136 – 142	Combined sources	7
Beta strandⁱ	147 – 149	Combined sources	3
Beta strandⁱ	153 – 161	Combined sources	9
Helixⁱ	162 – 169	Combined sources	8
Turnⁱ	170 – 173	Combined sources	4
Beta strandⁱ	176 – 179	Combined sources	4
Beta strandⁱ	182 – 186	Combined sources	5
Turnⁱ	188 – 190	Combined sources	3
Beta strandⁱ	286 – 288	Combined sources	3
Beta strandⁱ	290 – 295	Combined sources	6
Helixⁱ	302 – 307	Combined sources	6
Beta strandⁱ	315 – 325	Combined sources	11
Beta strandⁱ	327 – 334	Combined sources	8
Beta strandⁱ	336 – 338	Combined sources	3
Helixⁱ	339 – 345	Combined sources	7
Beta strandⁱ	352 – 355	Combined sources	4
Beta strandⁱ	358 – 362	Combined sources	5

Show more details

3D structure databases

ProteinModelPortalⁱ	P55795
SMRⁱ	P55795
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ

P55795

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	11 – 90	RRM 1PROSITE-ProRule annotationAdd BLAST	80
Domainⁱ	111 – 188	RRM 2PROSITE-ProRule annotationAdd BLAST	78
Repeatⁱ	234 – 249	1-1Add BLAST	16
Domainⁱ	289 – 364	RRM 3PROSITE-ProRule annotationAdd BLAST	76
Repeatⁱ	354 – 372	2-1Add BLAST	19
Repeatⁱ	374 – 392	2-2Add BLAST	19
Repeatⁱ	418 – 433	1-2Add BLAST	16

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	234 – 433	2 X 16 AA Gly-rich approximate repeatsAdd BLAST		200
Regionⁱ	354 – 392	2 X 19 AA perfect repeatsAdd BLAST		39

Keywords - Domainⁱ

Repeat

Phylogenomic databases

eggNOGⁱ	KOG4211 Eukaryota ENOG410Z6M0 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119102
HOGENOMⁱ	HOG000220896
HOVERGENⁱ	HBG055557
InParanoidⁱ	P55795
KEGG Orthology (KO) More...KOⁱ	K12898
OMAⁱ	GTADAYF
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0CTJ
PhylomeDBⁱ	P55795
TreeFamⁱ	TF316157

Family and domain databases

Gene3Dⁱ	3.30.70.330, 3 hits
InterProⁱ	View protein in InterPro IPR012677 Nucleotide-bd_a/b_plait_sf IPR035979 RBD_domain_sf IPR000504 RRM_dom IPR012996 Znf_CHHC
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00076 RRM_1, 3 hits PF08080 zf-RNPHF, 1 hit
SMARTⁱ	View protein in SMART SM00360 RRM, 3 hits
SUPFAMⁱ	SSF54928 SSF54928, 3 hits
PROSITEⁱ	View protein in PROSITE PS50102 RRM, 3 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P55795-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MMLSTEGREG FVVKVRGLPW SCSADEVMRF FSDCKIQNGT SGIRFIYTRE 
        60         70         80         90        100
GRPSGEAFVE LESEEEVKLA LKKDRETMGH RYVEVFKSNS VEMDWVLKHT 
       110        120        130        140        150
GPNSPDTAND GFVRLRGLPF GCSKEEIVQF FSGLEIVPNG MTLPVDFQGR 
       160        170        180        190        200
STGEAFVQFA SQEIAEKALK KHKERIGHRY IEIFKSSRAE VRTHYDPPRK 
       210        220        230        240        250
LMAMQRPGPY DRPGAGRGYN SIGRGAGFER MRRGAYGGGY GGYDDYGGYN 
       260        270        280        290        300
DGYGFGSDRF GRDLNYCFSG MSDHRYGDGG SSFQSTTGHC VHMRGLPYRA 
       310        320        330        340        350
TENDIYNFFS PLNPMRVHIE IGPDGRVTGE ADVEFATHED AVAAMAKDKA 
       360        370        380        390        400
NMQHRYVELF LNSTAGTSGG AYDHSYVELF LNSTAGASGG AYGSQMMGGM 
       410        420        430        440 
GLSNQSSYGG PASQQLSGGY GGGYGGQSSM SGYDQVLQEN SSDYQSNLA

Length:449

Mass (Da):49,264

Last modified:November 1, 1997 - v1

Checksum:ⁱC892523A638F07C7

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_077233	206	R → Q in MRXSB. 1 PublicationCorresponds to variant dbSNP:rs886039764EnsemblClinVar.	1
Natural variantⁱVAR_077234	206	R → W in MRXSB. 1 PublicationCorresponds to variant dbSNP:rs886039763EnsemblClinVar.	1
Natural variantⁱVAR_077235	209	P → L in MRXSB. 1 Publication	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U01923 mRNA No translation available. U78027 Genomic DNA Translation: AAB64202.1 AL035422 Genomic DNA No translation available. CH471115 Genomic DNA Translation: EAX02864.1 BC130343 mRNA Translation: AAI30344.1 BC130345 mRNA Translation: AAI30346.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS14485.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001027565.1, NM_001032393.2 NP_062543.1, NM_019597.4
UniGeneⁱ	Hs.432485

Genome annotation databases

Ensemblⁱ	ENST00000316594; ENSP00000361927; ENSG00000126945
GeneIDⁱ	3188
KEGGⁱ	hsa:3188
UCSC genome browser More...UCSCⁱ	uc004ehm.4 human

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P55795	Heterogeneous nuclear ribonucleoprotein H2		PONAB		449	UniRef100_P55795
Heterogeneous nuclear ribonucleoprotein H2		MACMU		449
HNRNPH2 isoform 1		PANTR		449
Heterogeneous nuclear ribonucleoprotein H2		CALJA		449
UPI0005F47829		COLAP		372
+1

Protein	Similar proteins		Species	Score	Length	Source
P55795	Heterogeneous nuclear ribonucleoprotein H	)	HUMAN		449	UniRef90_P31943
Heterogeneous nuclear ribonucleoprotein H2		MOUSE		449
Heterogeneous nuclear ribonucleoprotein H		RAT		449
Heterogeneous nuclear ribonucleoprotein H2		BOVIN		449
Heterogeneous nuclear ribonucleoprotein H2		PONAB		449
+362

Protein	Similar proteins		Species	Score	Length	Source
P55795	Heterogeneous nuclear ribonucleoprotein H	)	HUMAN		449	UniRef50_P31943
Heterogeneous nuclear ribonucleoprotein H2		MOUSE		449
Heterogeneous nuclear ribonucleoprotein H2		RAT		449
Heterogeneous nuclear ribonucleoprotein H2		BOVIN		449
Heterogeneous nuclear ribonucleoprotein H2		PONAB		449
+795

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U01923 mRNA No translation available. U78027 Genomic DNA Translation: AAB64202.1 AL035422 Genomic DNA No translation available. CH471115 Genomic DNA Translation: EAX02864.1 BC130343 mRNA Translation: AAI30344.1 BC130345 mRNA Translation: AAI30346.1
CCDSⁱ	CCDS14485.1
RefSeqⁱ	NP_001027565.1, NM_001032393.2 NP_062543.1, NM_019597.4
UniGeneⁱ	Hs.432485

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1WEZ	NMR	-	A	281-369	[»]
	1WG5	NMR	-	A	103-193	[»]
	6DG1	NMR	-	A	94-194	[»]
ProteinModelPortalⁱ	P55795
SMRⁱ	P55795
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	109429, 191 interactors
IntActⁱ	P55795, 95 interactors
MINTⁱ	P55795
STRINGⁱ	9606.ENSP00000361927

PTM databases

iPTMnetⁱ	P55795
PhosphoSitePlusⁱ	P55795
SwissPalmⁱ	P55795

Polymorphism and mutation databases

BioMutaⁱ	HNRNPH2
DMDMⁱ	2500576

2D gel databases

REPRODUCTION-2DPAGEⁱ	IPI00026230

REPRODUCTION-2DPAGEⁱ

IPI00026230

Proteomic databases

EPDⁱ	P55795
MaxQBⁱ	P55795
PaxDbⁱ	P55795
PeptideAtlasⁱ	P55795
PRIDEⁱ	P55795
ProteomicsDBⁱ	56867

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	3188
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000316594; ENSP00000361927; ENSG00000126945
GeneIDⁱ	3188
KEGGⁱ	hsa:3188
UCSCⁱ	uc004ehm.4 human

Organism-specific databases

CTDⁱ	3188
DisGeNETⁱ	3188
EuPathDBⁱ	HostDB:ENSG00000126945.8
GeneCardsⁱ	HNRNPH2
HGNCⁱ	HGNC:5042 HNRNPH2
HPAⁱ	CAB004436 HPA000914 HPA001359 HPA016884
MalaCardsⁱ	HNRNPH2
MIMⁱ	300610 gene 300986 phenotype
neXtProtⁱ	NX_P55795
OpenTargetsⁱ	ENSG00000126945
PharmGKBⁱ	PA162391316
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG4211 Eukaryota ENOG410Z6M0 LUCA
GeneTreeⁱ	ENSGT00760000119102
HOGENOMⁱ	HOG000220896
HOVERGENⁱ	HBG055557
InParanoidⁱ	P55795
KOⁱ	K12898
OMAⁱ	GTADAYF
OrthoDBⁱ	EOG091G0CTJ
PhylomeDBⁱ	P55795
TreeFamⁱ	TF316157

Enzyme and pathway databases

Reactomeⁱ	R-HSA-72163 mRNA Splicing - Major Pathway R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA

Reactomeⁱ

R-HSA-72163 mRNA Splicing - Major Pathway
R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA

Miscellaneous databases

EvolutionaryTraceⁱ	P55795
GeneWikiⁱ	HNRPH2
GenomeRNAiⁱ	3188
Protein Ontology More...PROⁱ	PR:P55795
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000126945 Expressed in 238 organ(s), highest expression level in choroid plexus epithelium
CleanExⁱ	HS_HNRNPH2
Genevisibleⁱ	P55795 HS

Family and domain databases

Gene3Dⁱ	3.30.70.330, 3 hits
InterProⁱ	View protein in InterPro IPR012677 Nucleotide-bd_a/b_plait_sf IPR035979 RBD_domain_sf IPR000504 RRM_dom IPR012996 Znf_CHHC
Pfamⁱ	View protein in Pfam PF00076 RRM_1, 3 hits PF08080 zf-RNPHF, 1 hit
SMARTⁱ	View protein in SMART SM00360 RRM, 3 hits
SUPFAMⁱ	SSF54928 SSF54928, 3 hits
PROSITEⁱ	View protein in PROSITE PS50102 RRM, 3 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	HNRH2_HUMAN
Accessionⁱ	P55795Primary (citable) accession number: P55795 Secondary accession number(s): A1L400, Q9HHA7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
	Last sequence update:	November 1, 1997
	Last modified:	November 7, 2018
	This is version 200 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome X
Human chromosome X: entries, gene names and cross-references to MIM
PDB cross-references
Index of Protein Data Bank (PDB) cross-references

UniProtKB

UniParc

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Supporting data

UniProtKB - P55795 (HNRH2_HUMAN)

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Heterogeneous nuclear ribonucleoprotein H2

HNRNPH2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Cytosol

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

2D gel databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

2D gel databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Keywords - Diseaseⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ