UniProtKB - P55735 (SEC13_HUMAN)
Protein SEC13 homolog
SEC13
Functioni
GO - Molecular functioni
- identical protein binding Source: IntAct
- structural molecule activity Source: InterPro
GO - Biological processi
- antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
- antigen processing and presentation of peptide antigen via MHC class I Source: Reactome
- COPII-coated vesicle budding Source: GO_Central
- COPII-coated vesicle cargo loading Source: UniProtKB
- COPII vesicle coating Source: Reactome
- intracellular protein transport Source: UniProtKB
- intracellular transport of virus Source: Reactome
- mRNA export from nucleus Source: Reactome
- positive regulation of TORC1 signaling Source: InterPro
- positive regulation of TOR signaling Source: SGD
- protein exit from endoplasmic reticulum Source: Ensembl
- regulation of cellular response to heat Source: Reactome
- regulation of gene silencing by miRNA Source: Reactome
- regulation of glycolytic process Source: Reactome
- tRNA export from nucleus Source: Reactome
- viral process Source: Reactome
- viral transcription Source: Reactome
Keywordsi
Biological process | ER-Golgi transport, mRNA transport, Protein transport, Translocation, Transport |
Enzyme and pathway databases
PathwayCommonsi | P55735 |
Reactomei | R-HSA-1169408, ISG15 antiviral mechanism R-HSA-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-159227, Transport of the SLBP independent Mature mRNA R-HSA-159230, Transport of the SLBP Dependant Mature mRNA R-HSA-159231, Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-165054, Rev-mediated nuclear export of HIV RNA R-HSA-168271, Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168276, NS1 Mediated Effects on Host Pathways R-HSA-168325, Viral Messenger RNA Synthesis R-HSA-168333, NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-170822, Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-180746, Nuclear import of Rev protein R-HSA-180910, Vpr-mediated nuclear import of PICs R-HSA-191859, snRNP Assembly R-HSA-204005, COPII-mediated vesicle transport R-HSA-2132295, MHC class II antigen presentation R-HSA-2467813, Separation of Sister Chromatids R-HSA-2500257, Resolution of Sister Chromatid Cohesion R-HSA-3108214, SUMOylation of DNA damage response and repair proteins R-HSA-3232142, SUMOylation of ubiquitinylation proteins R-HSA-3301854, Nuclear Pore Complex (NPC) Disassembly R-HSA-3371453, Regulation of HSF1-mediated heat shock response R-HSA-4085377, SUMOylation of SUMOylation proteins R-HSA-4551638, SUMOylation of chromatin organization proteins R-HSA-4570464, SUMOylation of RNA binding proteins R-HSA-4615885, SUMOylation of DNA replication proteins R-HSA-5578749, Transcriptional regulation by small RNAs R-HSA-5619107, Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5663220, RHO GTPases Activate Formins R-HSA-6784531, tRNA processing in the nucleus R-HSA-68877, Mitotic Prometaphase R-HSA-9609690, HCMV Early Events R-HSA-9610379, HCMV Late Events R-HSA-9615933, Postmitotic nuclear pore complex (NPC) reformation R-HSA-9639288, Amino acids regulate mTORC1 R-HSA-9648025, EML4 and NUDC in mitotic spindle formation R-HSA-983170, Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
SignaLinki | P55735 |
SIGNORi | P55735 |
Protein family/group databases
TCDBi | 1.I.1.1.3, the nuclear pore complex (npc) family |
Names & Taxonomyi
Protein namesi | Recommended name: Protein SEC13 homologCuratedAlternative name(s): GATOR complex protein SEC13Curated SEC13-like protein 1 SEC13-related protein |
Gene namesi | Name:SEC13 Synonyms:D3S1231E, SEC13A1 Publication, SEC13L1, SEC13R |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000157020.17 |
HGNCi | HGNC:10697, SEC13 |
MIMi | 600152, gene |
neXtProti | NX_P55735 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 1 Publication; Peripheral membrane protein 1 Publication; Cytoplasmic side 1 Publication
Lysosome
- Lysosome membrane 1 Publication
Nucleus
- nuclear pore complex 2 Publications
Other locations
- COPII-coated vesicle membrane 1 Publication; Peripheral membrane protein 1 Publication; Cytoplasmic side 1 Publication
Note: In interphase, localizes at both sides of the NPC.1 Publication
Cytosol
- cytosol Source: GO_Central
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: Reactome
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
Golgi apparatus
- Golgi membrane Source: GOC
Lysosome
- lysosomal membrane Source: UniProtKB
Nucleus
- nuclear envelope Source: UniProtKB
- nuclear pore outer ring Source: UniProtKB
- nucleoplasm Source: HPA
Other locations
- COPII vesicle coat Source: UniProtKB
- ER to Golgi transport vesicle membrane Source: Reactome
- GATOR2 complex Source: SGD
- host cell Source: GOC
- intracellular membrane-bounded organelle Source: HPA
Keywords - Cellular componenti
Cytoplasmic vesicle, Endoplasmic reticulum, Lysosome, Membrane, Nuclear pore complex, NucleusPathology & Biotechi
Organism-specific databases
DisGeNETi | 6396 |
OpenTargetsi | ENSG00000157020 |
PharmGKBi | PA35620 |
Miscellaneous databases
Pharosi | P55735, Tbio |
Polymorphism and mutation databases
BioMutai | SEC13 |
DMDMi | 50403748 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedCombined sources2 Publications | |||
ChainiPRO_0000051203 | 2 – 322 | Protein SEC13 homologAdd BLAST | 321 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylvalineCombined sources1 Publication | 1 | |
Modified residuei | 184 | PhosphoserineCombined sources | 1 | |
Modified residuei | 309 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | P55735 |
jPOSTi | P55735 |
MassIVEi | P55735 |
MaxQBi | P55735 |
PaxDbi | P55735 |
PeptideAtlasi | P55735 |
PRIDEi | P55735 |
ProteomicsDBi | 2150 56858 [P55735-1] |
PTM databases
iPTMneti | P55735 |
PhosphoSitePlusi | P55735 |
SwissPalmi | P55735 |
Expressioni
Gene expression databases
Bgeei | ENSG00000157020, Expressed in adenohypophysis and 247 other tissues |
ExpressionAtlasi | P55735, baseline and differential |
Genevisiblei | P55735, HS |
Organism-specific databases
HPAi | ENSG00000157020, Low tissue specificity |
Interactioni
Subunit structurei
At the nuclear pore: component of the Y-shaped Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex includes NUP160, NUP133, NUP107, NUP98, NUP85, NUP43, NUP37, SEH1 and SEC13. At the COPII coat complex: interacts with SEC31A and SEC31B. Within the GATOR complex, component of the GATOR2 subcomplex, made of MIOS, SEC13, SEH1L, WDR24 and WDR59. The GATOR complex strongly interacts with RRAGA/RRAGC and RRAGB/RRAGC heterodimers (PubMed:14517296, PubMed:16495487, PubMed:16957052, PubMed:18160040, PubMed:23723238). The GATOR2 complex interacts with CASTOR2 and CASTOR1; the interaction is negatively regulated by arginine (PubMed:26972053). The GATOR2 complex interacts with SESN1, SESN2 and SESN3; the interaction is negatively regulated by amino acids (PubMed:25263562, PubMed:25457612).
Interacts with SEC16A (PubMed:17428803, PubMed:19638414, PubMed:25201882).
Interacts with SEC16B (PubMed:22355596).
12 PublicationsBinary interactionsi
Hide detailsP55735
Isoform 1 [P55735-1]
With | #Exp. | IntAct |
---|---|---|
SEC31A - isoform 1 [O94979-1] | 9 | EBI-10045850,EBI-15564399 |
Isoform 3 [P55735-3]
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
BioGRIDi | 112296, 121 interactors |
ComplexPortali | CPX-873, Nuclear pore complex |
CORUMi | P55735 |
DIPi | DIP-39091N |
IntActi | P55735, 87 interactors |
MINTi | P55735 |
STRINGi | 9606.ENSP00000373312 |
Miscellaneous databases
RNActi | P55735, protein |
Structurei
Secondary structure
3D structure databases
SMRi | P55735 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P55735 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 11 – 50 | WD 1Add BLAST | 40 | |
Repeati | 55 – 96 | WD 2Add BLAST | 42 | |
Repeati | 101 – 144 | WD 3Add BLAST | 44 | |
Repeati | 148 – 204 | WD 4Add BLAST | 57 | |
Repeati | 210 – 253 | WD 5Add BLAST | 44 | |
Repeati | 260 – 299 | WD 6Add BLAST | 40 |
Sequence similaritiesi
Keywords - Domaini
Repeat, WD repeatPhylogenomic databases
eggNOGi | KOG1332, Eukaryota |
GeneTreei | ENSGT00940000153393 |
HOGENOMi | CLU_032441_0_1_1 |
InParanoidi | P55735 |
OMAi | REDNDRW |
OrthoDBi | 944756at2759 |
PhylomeDBi | P55735 |
TreeFami | TF300815 |
Family and domain databases
DisProti | DP01236 |
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR037596, Sec13 IPR037363, Sec13/Seh1_fam IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
PANTHERi | PTHR11024, PTHR11024, 1 hit PTHR11024:SF2, PTHR11024:SF2, 1 hit |
Pfami | View protein in Pfam PF00400, WD40, 5 hits |
SMARTi | View protein in SMART SM00320, WD40, 6 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS50082, WD_REPEATS_2, 3 hits PS50294, WD_REPEATS_REGION, 1 hit |
s (4+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 4 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 4 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MVSVINTVDT SHEDMIHDAQ MDYYGTRLAT CSSDRSVKIF DVRNGGQILI
60 70 80 90 100
ADLRGHEGPV WQVAWAHPMY GNILASCSYD RKVIIWREEN GTWEKSHEHA
110 120 130 140 150
GHDSSVNSVC WAPHDYGLIL ACGSSDGAIS LLTYTGEGQW EVKKINNAHT
160 170 180 190 200
IGCNAVSWAP AVVPGSLIDH PSGQKPNYIK RFASGGCDNL IKLWKEEEDG
210 220 230 240 250
QWKEEQKLEA HSDWVRDVAW APSIGLPTST IASCSQDGRV FIWTCDDASS
260 270 280 290 300
NTWSPKLLHK FNDVVWHVSW SITANILAVS GGDNKVTLWK ESVDGQWVCI
310 320
SDVNKGQGSV SASVTEGQQN EQ
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA8MXL6 | A8MXL6_HUMAN | GATOR complex protein SEC13 | SEC13 | 284 | Annotation score: | ||
E7ERC8 | E7ERC8_HUMAN | GATOR complex protein SEC13 | SEC13 | 86 | Annotation score: | ||
C9J0S2 | C9J0S2_HUMAN | Protein SEC13 homolog | SEC13 | 28 | Annotation score: | ||
C9JIB6 | C9JIB6_HUMAN | Protein SEC13 homolog | SEC13 | 24 | Annotation score: | ||
C9JBJ5 | C9JBJ5_HUMAN | Protein SEC13 homolog | SEC13 | 27 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 51 | A → V in L09260 (PubMed:7987303).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_053413 | 172 | S → L. Corresponds to variant dbSNP:rs34078590Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_046191 | 1 – 14 | Missing in isoform 2. 1 PublicationAdd BLAST | 14 | |
Alternative sequenceiVSP_054695 | 1 | M → MREPVLTWCVPLELLCSHPL PLSAFLKSQVKLYTYRACAG KDEMGKM in isoform 3. 1 Publication | 1 | |
Alternative sequenceiVSP_058966 | 1 | M → MGKM in isoform 4. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L09260 mRNA No translation available. AF052155 mRNA No translation available. AK301999 mRNA Translation: BAG63403.1 AC022384 Genomic DNA No translation available. BC002634 mRNA Translation: AAH02634.2 BC006167 mRNA Translation: AAH06167.1 BC091506 mRNA Translation: AAH91506.1 |
CCDSi | CCDS2599.1 [P55735-1] CCDS46751.1 [P55735-2] CCDS63540.1 [P55735-3] |
RefSeqi | NP_001129498.1, NM_001136026.2 [P55735-3] NP_001129704.1, NM_001136232.2 [P55735-2] NP_109598.2, NM_030673.3 [P55735-4] NP_899195.1, NM_183352.2 [P55735-1] XP_005265436.1, XM_005265379.2 [P55735-4] XP_016862508.1, XM_017007019.1 [P55735-3] |
Genome annotation databases
Ensembli | ENST00000337354; ENSP00000336566; ENSG00000157020 [P55735-4] ENST00000350697; ENSP00000312122; ENSG00000157020 [P55735-1] ENST00000383801; ENSP00000373312; ENSG00000157020 [P55735-3] ENST00000397109; ENSP00000380298; ENSG00000157020 [P55735-2] |
GeneIDi | 6396 |
KEGGi | hsa:6396 |
UCSCi | uc003bvm.5, human [P55735-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L09260 mRNA No translation available. AF052155 mRNA No translation available. AK301999 mRNA Translation: BAG63403.1 AC022384 Genomic DNA No translation available. BC002634 mRNA Translation: AAH02634.2 BC006167 mRNA Translation: AAH06167.1 BC091506 mRNA Translation: AAH91506.1 |
CCDSi | CCDS2599.1 [P55735-1] CCDS46751.1 [P55735-2] CCDS63540.1 [P55735-3] |
RefSeqi | NP_001129498.1, NM_001136026.2 [P55735-3] NP_001129704.1, NM_001136232.2 [P55735-2] NP_109598.2, NM_030673.3 [P55735-4] NP_899195.1, NM_183352.2 [P55735-1] XP_005265436.1, XM_005265379.2 [P55735-4] XP_016862508.1, XM_017007019.1 [P55735-3] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3BG0 | X-ray | 3.15 | A/D/E/H | 1-316 | [»] | |
3BG1 | X-ray | 3.00 | A/D/E/H | 1-316 | [»] | |
5A9Q | electron microscopy | 23.00 | 6/F/O/X | 1-322 | [»] | |
SMRi | P55735 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 112296, 121 interactors |
ComplexPortali | CPX-873, Nuclear pore complex |
CORUMi | P55735 |
DIPi | DIP-39091N |
IntActi | P55735, 87 interactors |
MINTi | P55735 |
STRINGi | 9606.ENSP00000373312 |
Protein family/group databases
TCDBi | 1.I.1.1.3, the nuclear pore complex (npc) family |
PTM databases
iPTMneti | P55735 |
PhosphoSitePlusi | P55735 |
SwissPalmi | P55735 |
Polymorphism and mutation databases
BioMutai | SEC13 |
DMDMi | 50403748 |
Proteomic databases
EPDi | P55735 |
jPOSTi | P55735 |
MassIVEi | P55735 |
MaxQBi | P55735 |
PaxDbi | P55735 |
PeptideAtlasi | P55735 |
PRIDEi | P55735 |
ProteomicsDBi | 2150 56858 [P55735-1] |
Protocols and materials databases
Antibodypediai | 25962, 235 antibodies |
DNASUi | 6396 |
Genome annotation databases
Ensembli | ENST00000337354; ENSP00000336566; ENSG00000157020 [P55735-4] ENST00000350697; ENSP00000312122; ENSG00000157020 [P55735-1] ENST00000383801; ENSP00000373312; ENSG00000157020 [P55735-3] ENST00000397109; ENSP00000380298; ENSG00000157020 [P55735-2] |
GeneIDi | 6396 |
KEGGi | hsa:6396 |
UCSCi | uc003bvm.5, human [P55735-1] |
Organism-specific databases
CTDi | 6396 |
DisGeNETi | 6396 |
EuPathDBi | HostDB:ENSG00000157020.17 |
GeneCardsi | SEC13 |
HGNCi | HGNC:10697, SEC13 |
HPAi | ENSG00000157020, Low tissue specificity |
MIMi | 600152, gene |
neXtProti | NX_P55735 |
OpenTargetsi | ENSG00000157020 |
PharmGKBi | PA35620 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1332, Eukaryota |
GeneTreei | ENSGT00940000153393 |
HOGENOMi | CLU_032441_0_1_1 |
InParanoidi | P55735 |
OMAi | REDNDRW |
OrthoDBi | 944756at2759 |
PhylomeDBi | P55735 |
TreeFami | TF300815 |
Enzyme and pathway databases
PathwayCommonsi | P55735 |
Reactomei | R-HSA-1169408, ISG15 antiviral mechanism R-HSA-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-159227, Transport of the SLBP independent Mature mRNA R-HSA-159230, Transport of the SLBP Dependant Mature mRNA R-HSA-159231, Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-165054, Rev-mediated nuclear export of HIV RNA R-HSA-168271, Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168276, NS1 Mediated Effects on Host Pathways R-HSA-168325, Viral Messenger RNA Synthesis R-HSA-168333, NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-170822, Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-180746, Nuclear import of Rev protein R-HSA-180910, Vpr-mediated nuclear import of PICs R-HSA-191859, snRNP Assembly R-HSA-204005, COPII-mediated vesicle transport R-HSA-2132295, MHC class II antigen presentation R-HSA-2467813, Separation of Sister Chromatids R-HSA-2500257, Resolution of Sister Chromatid Cohesion R-HSA-3108214, SUMOylation of DNA damage response and repair proteins R-HSA-3232142, SUMOylation of ubiquitinylation proteins R-HSA-3301854, Nuclear Pore Complex (NPC) Disassembly R-HSA-3371453, Regulation of HSF1-mediated heat shock response R-HSA-4085377, SUMOylation of SUMOylation proteins R-HSA-4551638, SUMOylation of chromatin organization proteins R-HSA-4570464, SUMOylation of RNA binding proteins R-HSA-4615885, SUMOylation of DNA replication proteins R-HSA-5578749, Transcriptional regulation by small RNAs R-HSA-5619107, Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5663220, RHO GTPases Activate Formins R-HSA-6784531, tRNA processing in the nucleus R-HSA-68877, Mitotic Prometaphase R-HSA-9609690, HCMV Early Events R-HSA-9610379, HCMV Late Events R-HSA-9615933, Postmitotic nuclear pore complex (NPC) reformation R-HSA-9639288, Amino acids regulate mTORC1 R-HSA-9648025, EML4 and NUDC in mitotic spindle formation R-HSA-983170, Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
SignaLinki | P55735 |
SIGNORi | P55735 |
Miscellaneous databases
BioGRID-ORCSi | 6396, 728 hits in 848 CRISPR screens |
ChiTaRSi | SEC13, human |
EvolutionaryTracei | P55735 |
GeneWikii | SEC13 |
GenomeRNAii | 6396 |
Pharosi | P55735, Tbio |
PROi | PR:P55735 |
RNActi | P55735, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000157020, Expressed in adenohypophysis and 247 other tissues |
ExpressionAtlasi | P55735, baseline and differential |
Genevisiblei | P55735, HS |
Family and domain databases
DisProti | DP01236 |
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR037596, Sec13 IPR037363, Sec13/Seh1_fam IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
PANTHERi | PTHR11024, PTHR11024, 1 hit PTHR11024:SF2, PTHR11024:SF2, 1 hit |
Pfami | View protein in Pfam PF00400, WD40, 5 hits |
SMARTi | View protein in SMART SM00320, WD40, 6 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS50082, WD_REPEATS_2, 3 hits PS50294, WD_REPEATS_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SEC13_HUMAN | |
Accessioni | P55735Primary (citable) accession number: P55735 Secondary accession number(s): A8MV37 Q9BUG7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 201 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human chromosome 3
Human chromosome 3: entries, gene names and cross-references to MIM - Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations