Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Deaminated glutathione amidase

Gene

sll0601

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes deaminated glutathione (dGSH, 2-oxoglutaramate) to alpha-ketoglutarate (alpha-KG) and cysteinylglycine, alpha-ketoglutaramate (a-KGM), and no activity on glutathione or L-glutamine. May function as a metabolite repair enzyme.By similarity

Catalytic activityi

N-(4-oxoglutarate)-L-cysteinylglycine + H2O = 2-oxoglutarate + L-cysteinylglycine.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei43Proton acceptorPROSITE-ProRule annotation1
Active sitei115Proton donorPROSITE-ProRule annotation1
Active sitei158NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Deaminated glutathione amidaseCurated (EC:3.5.1.-By similarity)
Short name:
dGSH amidaseCurated
Alternative name(s):
Nitrilase homolog 1
Short name:
syNit1
Gene namesi
Ordered Locus Names:sll0601
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002132621 – 272Deaminated glutathione amidaseAdd BLAST272

Proteomic databases

PaxDbiP55175
PRIDEiP55175

Interactioni

Protein-protein interaction databases

IntActiP55175, 2 interactors
STRINGi1148.SYNGTS_2407

Structurei

3D structure databases

ProteinModelPortaliP55175
SMRiP55175
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 253CN hydrolasePROSITE-ProRule annotationAdd BLAST253

Sequence similaritiesi

Phylogenomic databases

InParanoidiP55175
KOiK11206
OMAiTGKDHWQ
PhylomeDBiP55175

Family and domain databases

Gene3Di3.60.110.10, 1 hit
InterProiView protein in InterPro
IPR003010 C-N_Hydrolase
IPR036526 C-N_Hydrolase_sf
IPR001110 UPF0012_CS
PfamiView protein in Pfam
PF00795 CN_hydrolase, 1 hit
SUPFAMiSSF56317 SSF56317, 1 hit
PROSITEiView protein in PROSITE
PS50263 CN_HYDROLASE, 1 hit
PS01227 UPF0012, 1 hit

Sequencei

Sequence statusi: Complete.

P55175-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPYLAAALQ MTSRPNLTEN LQEAEELIDL AVRQGAELVG LPENFAFLGN
60 70 80 90 100
ETEKLEQATA IATATEKFLQ TMAQRFQVTI LAGGFPFPVA GEAGKAYNTA
110 120 130 140 150
TLIAPNGQEL ARYHKVHLFD VNVPDGNTYW ESATVMAGQK YPPVYHSDSF
160 170 180 190 200
GNLGLSICYD VRFPELYRYL SRQGADVLFV PAAFTAYTGK DHWQVLLQAR
210 220 230 240 250
AIENTCYVIA PAQTGCHYER RHTHGHAMII DPWGVILADA GEKPGLAIAE
260 270
INPDRLKQVR QQMPSLQHRV FV
Length:272
Mass (Da):30,191
Last modified:October 1, 1996 - v1
Checksum:i7787BA9B2BE003A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA Translation: BAA10370.1
PIRiS76524

Genome annotation databases

EnsemblBacteriaiBAA10370; BAA10370; BAA10370
KEGGisyn:sll0601

Similar proteinsi

Entry informationi

Entry nameiNIT1_SYNY3
AccessioniPrimary (citable) accession number: P55175
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health