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Protein

Vitellogenin-1

Gene

vit-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development.Curated

GO - Molecular functioni

  • lipid transporter activity Source: GO_Central
  • nutrient reservoir activity Source: UniProtKB-KW

Keywordsi

Molecular functionStorage protein

Names & Taxonomyi

Protein namesi
Recommended name:
Vitellogenin-1
Gene namesi
Name:vit-1
ORF Names:K09F5.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiK09F5.2 ; CE04746 ; WBGene00006925 ; vit-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000004153220 – 1616Vitellogenin-1Add BLAST1597

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi1270N-linked (GlcNAc...) asparagine1 Publication1

Keywords - PTMi

Glycoprotein

Proteomic databases

EPDiP55155
PaxDbiP55155
PeptideAtlasiP55155
PRIDEiP55155

PTM databases

iPTMnetiP55155

Expressioni

Gene expression databases

BgeeiWBGene00006925 Expressed in 5 organ(s), highest expression level in adult organism

Interactioni

Protein-protein interaction databases

BioGridi45958, 1 interactor
IntActiP55155, 1 interactor
STRINGi6239.K09F5.2

Structurei

3D structure databases

ProteinModelPortaliP55155
SMRiP55155
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 689VitellogeninPROSITE-ProRule annotationAdd BLAST666
Domaini1310 – 1512VWFDPROSITE-ProRule annotationAdd BLAST203

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG4338 Eukaryota
ENOG411104F LUCA
GeneTreeiENSGT00530000064273
HOGENOMiHOG000004768
InParanoidiP55155
OMAiNECETEE
OrthoDBiEOG091G07SB
PhylomeDBiP55155

Family and domain databases

Gene3Di1.25.10.20, 1 hit
2.30.230.10, 1 hit
InterProiView protein in InterPro
IPR015819 Lipid_transp_b-sht_shell
IPR001747 Lipid_transpt_N
IPR011030 Lipovitellin_superhlx_dom
IPR015816 Vitellinogen_b-sht_N
IPR015255 Vitellinogen_open_b-sht
IPR001846 VWF_type-D
PfamiView protein in Pfam
PF09172 DUF1943, 1 hit
PF01347 Vitellogenin_N, 1 hit
PF00094 VWD, 1 hit
SMARTiView protein in SMART
SM01169 DUF1943, 1 hit
SM00638 LPD_N, 1 hit
SM00216 VWD, 1 hit
SUPFAMiSSF48431 SSF48431, 1 hit
SSF56968 SSF56968, 2 hits
PROSITEiView protein in PROSITE
PS51211 VITELLOGENIN, 1 hit
PS51233 VWFD, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P55155-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRSIIIASIV ALAIAFSPAF ERTFEPKIDY HYKFDGLVLS GLPTASSELS
60 70 80 90 100
QSRFSARVRI QAVDDRHIHL QLVNIHMAAS HLPESEQIPS LNSMEQRELS
110 120 130 140 150
EEYKQMLKLP LRAQLRNGLI AELQFDKEDA EWSKNMKRAV VNMISFNPIA
160 170 180 190 200
PRNEIEKIES SYDKEEQSEE NTSFFTNEKT LEGDCQVAYT VIREQKKTII
210 220 230 240 250
TKSINFDKCT ERSEIAYGLR YSSECPECEK DTVLIRPQTV YTYILENEEL
260 270 280 290 300
KESEVRSLYT VNVNGQEVMK TETRSKLVLE ENHSIKSHIE KVNGEKESII
310 320 330 340 350
YSSRWEQLVE DFFKNGDKAE FAPFEKFPLD KKMHLIKTIT EQIQEVENNI
360 370 380 390 400
PETSHFLARL VRIFRTTSTS QLKEIHETLY VKADKKIQSL MEHALAIAGT
410 420 430 440 450
KNTIQHILVH IENEDIVPLE AAQLLKSIQE TPFPSQTIAE ALIKFAESRV
460 470 480 490 500
SKNNQVVRQS AWLAAGSVVR GIVDYKNIRP LVREDKRELK EKFLRVFMQQ
510 520 530 540 550
YKDAETTYEK ILALKSIGNA GLDISVNQLN EIIVDKRQLL PVRKEAIDAL
560 570 580 590 600
RLLKDTMPRK IQKVLLPIYK NRQYEPEIRM LALWRMMHTR PEESLLVQVV
610 620 630 640 650
SQMEKETNQQ VAALTHQMIR HFAKSTNPCY QRVAIVCSKV LSFTRYQPQE
660 670 680 690 700
QMIASSYAQL PLFLQNSFSG AQFDFAAIFE KNSFLLKDLH ASLDAVFGGN
710 720 730 740 750
WNKYFAQIGF SQQHMDKYVQ MALEKLESIE KESTTVVRGR RIQTGITLLK
760 770 780 790 800
ELALKMNIRA RPANYNEKDA FAMVYLRYKD MDYAILPVDT QLIEKLIEKY
810 820 830 840 850
ISNGKVQFSE IRRLLNQEHE FETHHAAYFY EAIRKFPTTL GLPLIVSGKI
860 870 880 890 900
PTVFSAEGQF SLGLEETELR LTVEARPSVA ATHVYEMRMF TPLFEQGVKS
910 920 930 940 950
VQSVRAYTPI KIQAVVGMKR NFEIVYKVVV PENQKSIISL TTRPVVFLRF
960 970 980 990 1000
PGFSKFEYIE AEERTVVVPQ WQQKTQEIEK VFNFLGLEVS TRGNILNQHT
1010 1020 1030 1040 1050
LENWLLAEQD FEVSVENKYR PAEFTARLTV GQLEKTELSQ IKYNKIFEKE
1060 1070 1080 1090 1100
FELEQENTES RREYFTKMVK SIQKEQGYKS VVSLRLEAPR DYTMNTEVTT
1110 1120 1130 1140 1150
VCDKQVRMCQ WEVEIRRSPI LEETKEWTLR SQLLVVRPEM PSSLRQLHDQ
1160 1170 1180 1190 1200
PHREVQLSLT STWGSQKKSE VTVNAQLQQS KEQKKYERNM DRHFNGMPEY
1210 1220 1230 1240 1250
ELLIKAARLN QINAVAEYKL TRETEQVLAR YFDLVKAYNY WTVSSRPENN
1260 1270 1280 1290 1300
ENDRVVVQLT VEPMSRQYVN ITMQSPIERV ELKNVQVPRV YLPSIAQRSV
1310 1320 1330 1340 1350
KHLLNEASGS VCKVQKNQIR TFDDVLYNTP LTTCYSLIAK DCSEEPTFAV
1360 1370 1380 1390 1400
LSKKTEKNSE EMIIKVIRGE QEIVAQLQNE EIRVKVDGKK ILSEDYSAHQ
1410 1420 1430 1440 1450
IERLGESDIV IELPEGEVRF DGYTIKTQLP SYSRKNQLCG LCGNNDDEST
1460 1470 1480 1490 1500
NEFYTSDNTE TKDIEEFHRS YLLKNEECEA EEERLSEKKN YRKYDERKYE
1510 1520 1530 1540 1550
SEEYSFEETY DYEQENTNKK QKNQRSQKKS DLVEKTQIKE FSHRICFSVE
1560 1570 1580 1590 1600
PVAECRRRGY EAVEQQQRKV RFTCLPRHSS EARRLVKEAR QGTVQLDDHK
1610
ISFVHSVQVP VACVAY
Length:1,616
Mass (Da):188,063
Last modified:November 1, 1997 - v2
Checksum:iF173D7C452D123F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080893 Genomic DNA Translation: CCD67565.1
PIRiT16600
RefSeqiNP_509305.1, NM_076904.8

Genome annotation databases

EnsemblMetazoaiK09F5.2; K09F5.2; WBGene00006925
GeneIDi181034
KEGGicel:CELE_K09F5.2
UCSCiK09F5.2 c. elegans

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080893 Genomic DNA Translation: CCD67565.1
PIRiT16600
RefSeqiNP_509305.1, NM_076904.8

3D structure databases

ProteinModelPortaliP55155
SMRiP55155
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi45958, 1 interactor
IntActiP55155, 1 interactor
STRINGi6239.K09F5.2

PTM databases

iPTMnetiP55155

Proteomic databases

EPDiP55155
PaxDbiP55155
PeptideAtlasiP55155
PRIDEiP55155

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiK09F5.2; K09F5.2; WBGene00006925
GeneIDi181034
KEGGicel:CELE_K09F5.2
UCSCiK09F5.2 c. elegans

Organism-specific databases

CTDi181034
WormBaseiK09F5.2 ; CE04746 ; WBGene00006925 ; vit-1

Phylogenomic databases

eggNOGiKOG4338 Eukaryota
ENOG411104F LUCA
GeneTreeiENSGT00530000064273
HOGENOMiHOG000004768
InParanoidiP55155
OMAiNECETEE
OrthoDBiEOG091G07SB
PhylomeDBiP55155

Miscellaneous databases

PROiPR:P55155

Gene expression databases

BgeeiWBGene00006925 Expressed in 5 organ(s), highest expression level in adult organism

Family and domain databases

Gene3Di1.25.10.20, 1 hit
2.30.230.10, 1 hit
InterProiView protein in InterPro
IPR015819 Lipid_transp_b-sht_shell
IPR001747 Lipid_transpt_N
IPR011030 Lipovitellin_superhlx_dom
IPR015816 Vitellinogen_b-sht_N
IPR015255 Vitellinogen_open_b-sht
IPR001846 VWF_type-D
PfamiView protein in Pfam
PF09172 DUF1943, 1 hit
PF01347 Vitellogenin_N, 1 hit
PF00094 VWD, 1 hit
SMARTiView protein in SMART
SM01169 DUF1943, 1 hit
SM00638 LPD_N, 1 hit
SM00216 VWD, 1 hit
SUPFAMiSSF48431 SSF48431, 1 hit
SSF56968 SSF56968, 2 hits
PROSITEiView protein in PROSITE
PS51211 VITELLOGENIN, 1 hit
PS51233 VWFD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiVIT1_CAEEL
AccessioniPrimary (citable) accession number: P55155
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: November 1, 1997
Last modified: November 7, 2018
This is version 115 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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Main funding by: National Institutes of Health

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