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Entry version 162 (02 Dec 2020)
Sequence version 1 (01 Oct 1996)
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Protein

Microfibrillar-associated protein 2

Gene

MFAP2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the elastin-associated microfibrils.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
P55001

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-1566948, Elastic fibre formation
R-HSA-2129379, Molecules associated with elastic fibres

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
P55001

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Microfibrillar-associated protein 2
Short name:
MFAP-2
Alternative name(s):
Microfibril-associated glycoprotein 1
Short name:
MAGP
Short name:
MAGP-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MFAP2
Synonyms:MAGP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

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EuPathDBi
HostDB:ENSG00000117122.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:7033, MFAP2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
156790, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P55001

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
4237

Open Targets

More...
OpenTargetsi
ENSG00000117122

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30769

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P55001, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MFAP2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
1708914

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Or 19Sequence analysisAdd BLAST17
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001868218 – 183Microfibrillar-associated protein 2Add BLAST166

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei18Pyrrolidone carboxylic acidBy similarity1
Modified residuei47SulfotyrosineBy similarity1
Modified residuei48SulfotyrosineBy similarity1
Modified residuei50SulfotyrosineBy similarity1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi153 ↔ 183PROSITE-ProRule annotation
Disulfide bondi160 ↔ 176PROSITE-ProRule annotation
Disulfide bondi169 ↔ 180PROSITE-ProRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Forms intermolecular disulfide bonds either with other MAGP-1 molecules or with other components of the microfibrils. May form transglutaminase cross-links.
O-glycosylated.

Keywords - PTMi

Disulfide bond, Glycoprotein, Pyrrolidone carboxylic acid, Sulfation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P55001

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P55001

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P55001

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P55001

PeptideAtlas

More...
PeptideAtlasi
P55001

PRoteomics IDEntifications database

More...
PRIDEi
P55001

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
56750 [P55001-1]
56751 [P55001-2]
56752 [P55001-3]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
P55001, 2 sites, 2 O-linked glycans (2 sites)

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P55001

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P55001

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000117122, Expressed in stromal cell of endometrium and 118 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P55001, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P55001, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000117122, Tissue enhanced (placenta)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a ternary complex with BGN and ELN.

Interacts with FBN1 (via N-terminal domain) and FBN2.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
110395, 5 interactors

Protein interaction database and analysis system

More...
IntActi
P55001, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000364685

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P55001, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P55001

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini153 – 183ShKTPROSITE-ProRule annotationAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi59 – 73Gln/Glu-richAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MFAP family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RXC2, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017736

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_124750_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P55001

Identification of Orthologs from Complete Genome Data

More...
OMAi
MRAACLF

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P55001

TreeFam database of animal gene trees

More...
TreeFami
TF333418

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008673, MAGP
IPR003582, ShKT_dom

The PANTHER Classification System

More...
PANTHERi
PTHR16485, PTHR16485, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05507, MAGP, 1 hit
PF01549, ShK, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51670, SHKT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform A (identifier: P55001-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRAAYLFLLF LPAGLLAQGQ YDLDPLPPFP DHVQYTHYSD QIDNPDYYDY
60 70 80 90 100
QEVTPRPSEE QFQFQSQQQV QQEVIPAPTP EPGNAELEPT EPGPLDCREE
110 120 130 140 150
QYPCTRLYSI HRPCKQCLNE VCFYSLRRVY VINKEICVRT VCAHEELLRA
160 170 180
DLCRDKFSKC GVMASSGLCQ SVAASCARSC GSC
Length:183
Mass (Da):20,826
Last modified:October 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA75BE15DC9629B26
GO
Isoform A' (identifier: P55001-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     13-13: Missing.

Show »
Length:182
Mass (Da):20,754
Checksum:iF8179D36FF49C25B
GO
Isoform B (identifier: P55001-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     13-42: Missing.

Show »
Length:153
Mass (Da):17,444
Checksum:i949A4852012F645A
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04277913 – 42Missing in isoform B. 1 PublicationAdd BLAST30
Alternative sequenceiVSP_04278013Missing in isoform A'. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U19718 mRNA Translation: AAA79920.1
CR407678 mRNA Translation: CAG28606.1
AK222751 mRNA Translation: BAD96471.1
AL049569 Genomic DNA No translation available.
CH471134 Genomic DNA Translation: EAW94821.1
BC015039 mRNA Translation: AAH15039.1
H27217 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS174.1 [P55001-1]
CCDS44071.1 [P55001-2]

Protein sequence database of the Protein Information Resource

More...
PIRi
I38923

NCBI Reference Sequences

More...
RefSeqi
NP_001128719.1, NM_001135247.1 [P55001-2]
NP_001128720.1, NM_001135248.1 [P55001-2]
NP_002394.1, NM_002403.3 [P55001-1]
NP_059453.1, NM_017459.2 [P55001-1]
XP_011539778.1, XM_011541476.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000375534; ENSP00000364684; ENSG00000117122 [P55001-2]
ENST00000375535; ENSP00000364685; ENSG00000117122 [P55001-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4237

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:4237

UCSC genome browser

More...
UCSCi
uc001azw.4, human [P55001-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U19718 mRNA Translation: AAA79920.1
CR407678 mRNA Translation: CAG28606.1
AK222751 mRNA Translation: BAD96471.1
AL049569 Genomic DNA No translation available.
CH471134 Genomic DNA Translation: EAW94821.1
BC015039 mRNA Translation: AAH15039.1
H27217 mRNA No translation available.
CCDSiCCDS174.1 [P55001-1]
CCDS44071.1 [P55001-2]
PIRiI38923
RefSeqiNP_001128719.1, NM_001135247.1 [P55001-2]
NP_001128720.1, NM_001135248.1 [P55001-2]
NP_002394.1, NM_002403.3 [P55001-1]
NP_059453.1, NM_017459.2 [P55001-1]
XP_011539778.1, XM_011541476.2

3D structure databases

SMRiP55001
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi110395, 5 interactors
IntActiP55001, 1 interactor
STRINGi9606.ENSP00000364685

PTM databases

GlyGeniP55001, 2 sites, 2 O-linked glycans (2 sites)
iPTMnetiP55001
PhosphoSitePlusiP55001

Polymorphism and mutation databases

BioMutaiMFAP2
DMDMi1708914

Proteomic databases

jPOSTiP55001
MassIVEiP55001
MaxQBiP55001
PaxDbiP55001
PeptideAtlasiP55001
PRIDEiP55001
ProteomicsDBi56750 [P55001-1]
56751 [P55001-2]
56752 [P55001-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1230, 177 antibodies

The DNASU plasmid repository

More...
DNASUi
4237

Genome annotation databases

EnsembliENST00000375534; ENSP00000364684; ENSG00000117122 [P55001-2]
ENST00000375535; ENSP00000364685; ENSG00000117122 [P55001-1]
GeneIDi4237
KEGGihsa:4237
UCSCiuc001azw.4, human [P55001-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4237
DisGeNETi4237
EuPathDBiHostDB:ENSG00000117122.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MFAP2
HGNCiHGNC:7033, MFAP2
HPAiENSG00000117122, Tissue enhanced (placenta)
MIMi156790, gene
neXtProtiNX_P55001
OpenTargetsiENSG00000117122
PharmGKBiPA30769

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502RXC2, Eukaryota
GeneTreeiENSGT00390000017736
HOGENOMiCLU_124750_0_0_1
InParanoidiP55001
OMAiMRAACLF
PhylomeDBiP55001
TreeFamiTF333418

Enzyme and pathway databases

PathwayCommonsiP55001
ReactomeiR-HSA-1566948, Elastic fibre formation
R-HSA-2129379, Molecules associated with elastic fibres
SignaLinkiP55001

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
4237, 4 hits in 840 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
MFAP2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
4237
PharosiP55001, Tbio

Protein Ontology

More...
PROi
PR:P55001
RNActiP55001, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000117122, Expressed in stromal cell of endometrium and 118 other tissues
ExpressionAtlasiP55001, baseline and differential
GenevisibleiP55001, HS

Family and domain databases

InterProiView protein in InterPro
IPR008673, MAGP
IPR003582, ShKT_dom
PANTHERiPTHR16485, PTHR16485, 1 hit
PfamiView protein in Pfam
PF05507, MAGP, 1 hit
PF01549, ShK, 1 hit
PROSITEiView protein in PROSITE
PS51670, SHKT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMFAP2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P55001
Secondary accession number(s): Q53X60, Q5JXY0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: December 2, 2020
This is version 162 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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