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Entry version 156 (12 Aug 2020)
Sequence version 1 (01 Oct 1996)
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Protein

[Protein ADP-ribosylarginine] hydrolase

Gene

ADPRH

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Specifically acts as a arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+1 PublicationNote: Binds 2 magnesium ions per subunit.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi54Magnesium 1Combined sources2 Publications1
Metal bindingi55Magnesium 1Combined sources2 Publications1
Metal bindingi56Magnesium 1Combined sources2 Publications1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei85SubstrateCombined sources1 Publication1
Binding sitei124Substrate; via carbonyl oxygenCombined sources1 Publication1 Publication1
Binding sitei130Substrate; via amide nitrogenCombined sources1 Publication1 Publication1
Metal bindingi302Magnesium 21 Publication1
Metal bindingi304Magnesium 1Combined sources2 Publications1
Metal bindingi304Magnesium 21 Publication1
Metal bindingi305Magnesium 21 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
LigandMagnesium, Metal-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
P54922

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
[Protein ADP-ribosylarginine] hydrolase (EC:3.2.2.191 Publication)
Short name:
ADP-ribosylarginine hydrolase
Short name:
hARH11 Publication
Alternative name(s):
ADP-ribose-L-arginine cleaving enzyme
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ADPRH
Synonyms:ARH1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000144843.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:269, ADPRH

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
603081, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P54922

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi54S → A: Complete loss of activity. 1 Publication1
Mutagenesisi55D → N: Complete loss of activity. 1 Publication1
Mutagenesisi56D → N: Complete loss of activity. 1 Publication1
Mutagenesisi302D → N: Complete loss of activity. 1 Publication1
Mutagenesisi305S → A: Complete loss of activity. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
141

Open Targets

More...
OpenTargetsi
ENSG00000144843

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA24590

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P54922, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ADPRH

Domain mapping of disease mutations (DMDM)

More...
DMDMi
1703392

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001572831 – 357[Protein ADP-ribosylarginine] hydrolaseAdd BLAST357

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P54922

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P54922

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P54922

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P54922

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P54922

PeptideAtlas

More...
PeptideAtlasi
P54922

PRoteomics IDEntifications database

More...
PRIDEi
P54922

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
56748

2D gel databases

USC-OGP 2-DE database

More...
OGPi
P54922

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P54922

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P54922

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000144843, Expressed in gastrocnemius and 170 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P54922, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P54922, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000144843, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
106651, 10 interactors

Protein interaction database and analysis system

More...
IntActi
P54922, 9 interactors

Molecular INTeraction database

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MINTi
P54922

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000420200

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P54922, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1357
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P54922

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P54922

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni101 – 103Substrate bindingCombined sources1 Publication3
Regioni163 – 165Substrate bindingCombined sources1 Publication1 Publication3
Regioni263 – 265Substrate bindingCombined sources1 Publication1 Publication3
Regioni269 – 270Substrate bindingCombined sources1 Publication1 Publication2

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ADP-ribosylglycohydrolase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QPMI, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063627

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_047061_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P54922

KEGG Orthology (KO)

More...
KOi
K01245

Identification of Orthologs from Complete Genome Data

More...
OMAi
NRKWEFL

Database of Orthologous Groups

More...
OrthoDBi
1112828at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P54922

TreeFam database of animal gene trees

More...
TreeFami
TF329417

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.4080.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012108, ADP-ribosylarg_hydro
IPR005502, Ribosyl_crysJ1
IPR036705, Ribosyl_crysJ1_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03747, ADP_ribosyl_GH, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF016939, ADP_ribslarg_hdr, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101478, SSF101478, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P54922-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKYVAAMVL SAAGDALGYY NGKWEFLQDG EKIHRQLAQL GGLDALDVGR
60 70 80 90 100
WRVSDDTVMH LATAEALVEA GKAPKLTQLY YLLAKHYQDC MEDMDGRAPG
110 120 130 140 150
GASVHNAMQL KPGKPNGWRI PFNSHEGGCG AAMRAMCIGL RFPHHSQLDT
160 170 180 190 200
LIQVSIESGR MTHHHPTGYL GALASALFTA YAVNSRPPLQ WGKGLMELLP
210 220 230 240 250
EAKKYIVQSG YFVEENLQHW SYFQTKWENY LKLRGILDGE SAPTFPESFG
260 270 280 290 300
VKERDQFYTS LSYSGWGGSS GHDAPMIAYD AVLAAGDSWK ELAHRAFFHG
310 320 330 340 350
GDSDSTAAIA GCWWGVMYGF KGVSPSNYEK LEYRNRLEET ARALYSLGSK

EDTVISL
Length:357
Mass (Da):39,507
Last modified:October 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4E23B12FAE84F12B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JZW7C9JZW7_HUMAN
[Protein ADP-ribosylarginine] hydro...
ADPRH
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L13291 mRNA Translation: AAA35555.1
AK313369 mRNA Translation: BAG36168.1
CH471052 Genomic DNA Translation: EAW79562.1
CH471052 Genomic DNA Translation: EAW79563.1
BC063883 mRNA Translation: AAH63883.1
BC074769 mRNA Translation: AAH74769.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2990.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B47411

NCBI Reference Sequences

More...
RefSeqi
NP_001116.1, NM_001125.3
NP_001278878.1, NM_001291949.1
NP_001278879.1, NM_001291950.1
XP_011510740.1, XM_011512438.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000357003; ENSP00000349496; ENSG00000144843
ENST00000465513; ENSP00000417430; ENSG00000144843
ENST00000478399; ENSP00000420200; ENSG00000144843
ENST00000478927; ENSP00000417528; ENSG00000144843

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
141

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:141

UCSC genome browser

More...
UCSCi
uc003ecs.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13291 mRNA Translation: AAA35555.1
AK313369 mRNA Translation: BAG36168.1
CH471052 Genomic DNA Translation: EAW79562.1
CH471052 Genomic DNA Translation: EAW79563.1
BC063883 mRNA Translation: AAH63883.1
BC074769 mRNA Translation: AAH74769.1
CCDSiCCDS2990.1
PIRiB47411
RefSeqiNP_001116.1, NM_001125.3
NP_001278878.1, NM_001291949.1
NP_001278879.1, NM_001291950.1
XP_011510740.1, XM_011512438.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3HFWX-ray1.92A1-357[»]
6G28X-ray1.23A1-357[»]
6G2AX-ray1.80A1-357[»]
6IUXX-ray1.20A2-357[»]
SMRiP54922
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi106651, 10 interactors
IntActiP54922, 9 interactors
MINTiP54922
STRINGi9606.ENSP00000420200

PTM databases

iPTMnetiP54922
PhosphoSitePlusiP54922

Polymorphism and mutation databases

BioMutaiADPRH
DMDMi1703392

2D gel databases

OGPiP54922

Proteomic databases

EPDiP54922
jPOSTiP54922
MassIVEiP54922
MaxQBiP54922
PaxDbiP54922
PeptideAtlasiP54922
PRIDEiP54922
ProteomicsDBi56748

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
32747, 130 antibodies

The DNASU plasmid repository

More...
DNASUi
141

Genome annotation databases

EnsembliENST00000357003; ENSP00000349496; ENSG00000144843
ENST00000465513; ENSP00000417430; ENSG00000144843
ENST00000478399; ENSP00000420200; ENSG00000144843
ENST00000478927; ENSP00000417528; ENSG00000144843
GeneIDi141
KEGGihsa:141
UCSCiuc003ecs.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
141
DisGeNETi141
EuPathDBiHostDB:ENSG00000144843.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ADPRH
HGNCiHGNC:269, ADPRH
HPAiENSG00000144843, Low tissue specificity
MIMi603081, gene
neXtProtiNX_P54922
OpenTargetsiENSG00000144843
PharmGKBiPA24590

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QPMI, Eukaryota
GeneTreeiENSGT00530000063627
HOGENOMiCLU_047061_0_0_1
InParanoidiP54922
KOiK01245
OMAiNRKWEFL
OrthoDBi1112828at2759
PhylomeDBiP54922
TreeFamiTF329417

Enzyme and pathway databases

PathwayCommonsiP54922

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
141, 7 hits in 871 CRISPR screens
EvolutionaryTraceiP54922

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
141
PharosiP54922, Tbio

Protein Ontology

More...
PROi
PR:P54922
RNActiP54922, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000144843, Expressed in gastrocnemius and 170 other tissues
ExpressionAtlasiP54922, baseline and differential
GenevisibleiP54922, HS

Family and domain databases

Gene3Di1.10.4080.10, 1 hit
InterProiView protein in InterPro
IPR012108, ADP-ribosylarg_hydro
IPR005502, Ribosyl_crysJ1
IPR036705, Ribosyl_crysJ1_sf
PfamiView protein in Pfam
PF03747, ADP_ribosyl_GH, 1 hit
PIRSFiPIRSF016939, ADP_ribslarg_hdr, 1 hit
SUPFAMiSSF101478, SSF101478, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiADPRH_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P54922
Secondary accession number(s): B2R8H1, D3DN83
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: August 12, 2020
This is version 156 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
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